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3BIO: Journal of Biological Science, Technology and Management
Published by Institut Teknologi Bandung
ISSN : -     EISSN : 26558777     DOI : http://dx.doi.org/10.5614%2F3bio.2020.2.1
Core Subject : Science, Agriculture, Engineering,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Immunology & microbiology Neuroscience
3Bio: Journal of Biological Science, Technology and Management is an interdisciplinary peer-reviewed journal in a wide aspect related to the field of life sciences and other related fields of study. The journal aims to promote scientific discourse and disseminate research on various branches and applications of bio-science, biotechnology and bio-based management. This journal invites original empirical research, literature reviews, theoretical or methodological contributions, or short communications on, but not limited to, the following topics: - Ecology and Biosystematics - Microbiology - Genetics and Molecular Biology - Animal Development and Physiology - Plant Development and Physiology - Entomology - Biomedical science - Biochemistry - Agronomy - Forestry - Bioengineering - Bioethics - Management of Biological Resources The journal also invites contributions from other associated disciplines. This journal is an open-access journal. Readers may read, download, copy, distribute, print, search, or link to the full texts of these articles without any charge, provided that readers acknowledge the Creative Commons attached to the articles. All submitted papers are reviewed by at least two referees before being accepted for publication, following a double-blind review process. This journal is delivered in an academic English and rigorously edited to provide a quality standard of a scientific journal. This journal is managed by the School of Life Sciences and Technology, Institut Teknologi Bandung, Indonesia.
Arjuna Subject : Ilmu Pertanian dan Biologi (Semua) - Ilmu Pertanian dan Biologi (Lain-Lain)
Articles 68 Documents
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Optimal Feeding Frequency on the Growth Performance of Whiteleg Shrimp (Litopenaeus vannamei) during Grow-out Phase Alif Ihsanario; Ahmad Ridwan
3BIO: Journal of Biological Science, Technology and Management Vol. 3 No. 1 (2021)
Publisher : School of Life Sciences and Technology, Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/3bio.2021.3.1.5

Abstract

Whiteleg shrimp (Litopenaeus vannamei) is a fisheries commodity that has experienced a vast increase in production since the early 1970s. As one of the largest contributors to the global shrimp market, Indonesia always tried to increase its shrimp production. To fulfill the global market demand, whiteleg shrimp farmers have met with countless obstacles, e.g., sub-optimal growth problem. Optimal feed management is one of the determining factors that account for the growth and production efficiency of whiteleg shrimp. Feed management practices include feeding frequency, methods of feed monitoring, and controlling. This literature review aims to provide an insight into the optimal feeding frequency for the growth, survival, and feed efficiency of whiteleg shrimp production. The method used for this review was a narrative review approach following the PRISMA scheme for literature sorting, which includes identification, screening, eligibility test, and inclusion. There were eight primary literatures from journals with H indices of 18, 50, 55, 72, 80, and 164 (four articles from Q1 journals and three from Q2 journals) and one article without index. Data analysis revealed that the growth rate was significantly affected by the feeding frequency of on-demand feeding system (AQ1) (P < 0.05), although no significant difference was found in regards to the survival rate and the FCR (P > 0.05). The optimal feeding frequency for industrial-scale shrimp production was found in the on-demand feeding system (AQ1).
High-Fat Diets-Induced Metabolic Disorders to Study Molecular Mechanism of Hyperlipidemia in Rats harfi maulana; Ahmad Ridwan
3BIO: Journal of Biological Science, Technology and Management Vol. 3 No. 2 (2021)
Publisher : School of Life Sciences and Technology, Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/3bio.2021.3.2.5

Abstract

Hyperlipidemia is a lipid metabolism disorder occurring due to consumption of a high-fat diet (HFD), which contributes to atherosclerosis and cardiovascular disease development. HFD causes metabolic problems in Rodentia animals like human metabolic abnormalities, making it a popular model for studying the signaling systems involved. Hyperlipidemia is a condition in which the body's cholesterol levels elevate. In recent years, several studies have investigated the relationship between HFD feeding and hyperlipidemia and signaling pathways involved in cholesterol homeostasis. However, this signaling mechanism in lipid metabolism has not been fully explained, so additional analysis is needed. The present study aimed to investigate the mechanism that occurs from hyperlipidemia due to HFD feeding. The method used is a literature review approach following the PRISMA scheme for selecting the primary literature, including identification, screening, eligibility test, and inclusion. Eleven articles included primary literature with credibility (H-index) of 20, 33, 71, 92, 93, 162, 180, 192, and 332 (six articles from Q1 journals and five from Q2 journals). Long-term administration of HFD directly affects lipid metabolism, including an increase in the concentration of total cholesterol, triglycerides, LDL, and a decrease in HDL concentration, followed by an increase in body weight. In addition, HFD also disrupts adipose tissue and insulin resistance. The conclusion of this study is that HFD can cause hyperlipidemia either directly or indirectly by inducing insulin resistance, which contributes to lipid metabolism disorders.  
The Suitability Analysis of Kampung Pasundan Cisamaya in Mount Ciremai National Park Area as Healing Forest Site Hikmat Ramdan; Sheilla Ayu Prameswari; Angga Dwiartama
3BIO: Journal of Biological Science, Technology and Management Vol. 3 No. 2 (2021)
Publisher : School of Life Sciences and Technology, Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/3bio.2021.3.2.4

Abstract

Forests are ecosystems that are comfortable for human health. Spots from the forest ecosystem site suitable for healing forest must be identified. The research aims to analyze the suitability of Kampung Pasundan Cisamaya (KPC) for healing forest activities. The research method refers to the Draft Indonesian National Standard Number 9006:2021 concerning Forest tourism for health therapy (healing forest). The results showed that the KPC site is suitable for healing forest activities. Five reconnection activities with nature, namely invitation by air, invitation by vegetation, invitation by land, invitation by water, and release emotion, can be carried out well in several spots on KPC's healing forest track. Healing forest activities regularly and adequately has a positive impact on health.
A Review on The Production of Fermented Beverage as a Post-Harvest Processing Alternative For Mango, Banana and Purple Sweet Potato Sonia Yurista; Pingkan Aditiawati
3BIO: Journal of Biological Science, Technology and Management Vol. 3 No. 2 (2021)
Publisher : School of Life Sciences and Technology, Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/3bio.2021.3.2.3

Abstract

West Java is one of the regions in Indonesia that produces large numbers of mango, banana, and purple sweet potato. After harvesting, these commodities will undergo physical, chemical, and physiological changes so that further post-harvest processing is needed. One of the post-harvest processing that can be done is fermentation. Fermenting mango, banana, and purple sweet potato into wine is a simple and efficient method that can increase the economic value of the product. Wine is an alcoholic beverage made from grapes; however, any fruit and tuber could be used for wine-making. The article reviews the potential of mango, banana, and purple sweet potato for wine production, the microbes involved, and pretreatments of mango, banana, and purple sweet potato.
Biological, Technical, and Financial Feasibilities Study of Spirulina sp. Biomass Production with Modified Commercial Medium in Indonesia Chessandy Rilisa; Gede Suantika
3BIO: Journal of Biological Science, Technology and Management Vol. 3 No. 2 (2021)
Publisher : School of Life Sciences and Technology, Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/3bio.2021.3.2.2

Abstract

Spirulina sp. is the most common cyanobacteria commodity used in the bioindustry for functional food, source of protein, bioactive compounds, and biopigment. Production of Spirulina sp. still facing several problems such as high cost of culture medium with the less effective result, especially in developing countries. The medium was modified with commercial chemicals and fertilizers locally available in Indonesia to reduce the production cost. This study aimed to assess the biological, technical, and financial feasibility of Spirulina sp. biomass production using a modified commercial medium. Based on the biological feasibility study, the modified commercial medium (ZK1 and ZK2) gives a similar result to the standard medium, equal for growth rate and protein content. However, the result contains lower fat, carbohydrates, and biopigment. The financial feasibility analysis suggested that the system is feasible starting from 1.2-1.5 kg biomass production in a month. The best result gained on the production capacity of 5 kg biomass using ZK2 medium, with NPV of IDR 183,208,962 (US$12,769), IRR of 73%, B/C ratio of 7.8, and payback period in 7 months. It can be concluded that modified commercial medium was biologically, technically, and financially feasible to be applied in industrial biomass production of Spirulina sp.
Spatial Distributions and Model Selections of Commercial Estuarine Fish (Sciaenidae) Populations Related to Water Quality, Chl-a, and AML in Musi River mouth, South Sumatra Andriwibowo Andriwibowo; Adi Basukriadi; Erwin Nurdin
3BIO: Journal of Biological Science, Technology and Management Vol. 3 No. 2 (2021)
Publisher : School of Life Sciences and Technology, Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/3bio.2021.3.2.1

Abstract

Estuary and river mouth are essential habitats for many commercial estuarine fishes, including the Sciaenidae family. While recently, estuaries have been threatened by anthropogenic marine litter (AML) transported from nearby land and river. An important type of AML is plastic litter since it takes a long degradation time. In the South Sumatra Province, Indonesia, one of the vital estuaries is the Musi estuary. This paper aims to map the spatial distributions of two Sciaenids, including Panna microdon and Otolithoides pama, and Sciaenid’s environmental covariates, including water quality, chlorophyll a, and plastic litters in Musi estuary and model the correlations of Sciaenids with their covariates. The maps were developed using GIS, and the model was validated using AIC methods. The data were collected from 3 river mouths in the west, central, and east of the Musi estuary. The data showed that the populations of both Sciaenids were higher in the east river mouth rather than in the west. Sciaenid populations were positively correlated with high salinity, DO, chlorophyll a, moderate transparency, and low temperature. A high load of AML’s frequency (7.54 items/m2) and weights (36.8 gram/m2) has reduced both Sciaenid populations in the central river mouth of the estuary. In contrast, low AML loads in the east have correlated with high Sciaenid populations. Model selection based on AIC values shows the best model for P.microdon retained an effect of AML weight with AIC values of 22.591 and 28.321 for O. pama. This concludes that the weight of plastic litter in estuary water was the main limiting factor for Sciaenid populations in Musi.
Analyzing the Changes in Land Cover and Land Surface Temperature (LST) in the North Bandung Area (NBA) Dian Rosleine; Muhammad Irfan
3BIO: Journal of Biological Science, Technology and Management Vol. 3 No. 2 (2021)
Publisher : School of Life Sciences and Technology, Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/3bio.2021.3.2.6

Abstract

North Bandung Area (NBA) was designated as a protected area to regulate the water system around Bandung City. Land conversion from vegetated land into built-up areas can decrease groundwater, increase the risk of floods, landslides, and Land Surface Temperature (LST). This study was conducted to describe LST distribution based on land cover types in specific years of 2010, 2014, and 2018. Landsat 5 and 8 Surface Reflectance (SR) Tier 1 imagery data, West Java land cover maps established by BAPPEDA West Java, and RBI administration maps at a scale of 1: 25,000 were used to generate a map of land cover and LST in this research. There are four land cover classes in NBA, i.e., vegetation, water bodies, open areas, and constructed areas. Within eight years observation (2010 to 2018), bare land decreased from 67.6% (2010) to 57.5% (2018). However, coverage of constructed areas increased within eight years of observation from 22.8% to 27.7 %. In addition, due to the reforestation program, vegetation coverage has slightly increased from 9.6% to 14.7%. LST can be classified into three classes, i.e., low, medium, and high temperature. The area with low and medium-class temperatures decreased from 19% to 16% and 61.3% to 51.7%, respectively. However, high LST increased in NBA 18.7% to 30.3%. The enhancement of 5% vegetation area did not significantly reduce land surface temperature in NBA due to forest conversion to constructed area. Therefore, vegetation coverage must be escalated by reforestation program around NBA to reduce land surface temperature.
Wheatgrass microgreen with high antioxidants content in an urban indoor farming system Myrea Chalil; Karlia Meitha; Ramadhani Eka Putra; Fathia Aulia Rahmah; Ridho R Sinatra; Anindha Ajeng Putri Winanta
3BIO: Journal of Biological Science, Technology and Management Vol. 4 No. 1 (2022)
Publisher : School of Life Sciences and Technology, Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/3bio.2022.4.1.4

Abstract

Urban lifestyle is identical to stressful life and sedentary habit, leading to the increase of chronic conditions such as diabetes and cardiovascular-related diseases. Antioxidants are renowned for maintaining cellular function by quenching radicals produced in stressful conditions or infection. Fresh fruits and vegetables are the primary sources of antioxidants, but the long postharvest and transport system may reduce the benefits for the urban population. Hence, we designed a cultivation method to produce wheatgrass microgreens with high antioxidants in an urban indoor farming system. Generally, plants require light at the wavelength of 663 and 642 nm (red) and 430 nm and 453 nm (blue) to allow photosynthesis and production of secondary metabolites, such as antioxidants. We applied the LED lights with an RGB ratio of 91R/9B, 83R/17B, 47R/53B, 35R/65B, and white florescent as the control. Our results showed that 91R/9B reduced fresh mass and chlorophyll content, which might be due to the suppression of photosynthesis capacity. Interestingly, we found a significant (p<0.05) increase in carotenoids and flavonoid contents due to light combinations of 35R/65B and 83R/17B, respectively. However, the total antioxidants capacity was similar among all treatments. Carotenoids and flavonoids are among the antioxidants with a significant role in decreasing the risks of chronic diseases and their potential as antiviral agents. This cultivation system of wheat microgreen could be a promising solution to routinely supply carotenoids and flavonoids to the urban population. Further, it is also considered more environmentally friendly as it could be performed in a limited amount of land (vertically) and potentially use less energy for distribution.
Autosterilization Effect of Gamma Radiation in Non-sterile Radiopharmaceuticals Widyastuti Widjaksana; Enny Lestari; Maskur Maskur; Sudarsih Sudarsih
3BIO: Journal of Biological Science, Technology and Management Vol. 4 No. 1 (2022)
Publisher : School of Life Sciences and Technology, Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/3bio.2022.4.1.3

Abstract

Gamma radiation is commonly used in sterilizing various products because of its microbial-killing property. Several radiopharmaceuticals are processed aseptically, which requires a well-managed GMP-based facility. This study aims to ensure that radiopharmaceutical can behave as an auto sterilizing agent since it contains radionuclide that emits gamma radiation. Sm-153-ethylenediaminetetramethylenephosphonate (Sm-153-EDTMP) and I-131-Hippuran were used as models in this study, in which various radioactivities of these products were added into non-sterile vials in the non-aseptic working area and tested for sterility using direct inoculation method. The result showed that samples containing 7 mCi of Sm-153-EDTMP and less than 2 mCi of I-131-orthoiodohippurate (I-131-Hippuran) changed the clarity of the media, but not for those containing higher radioactivity. The results showed that Sm-153-EDTMP and I-131-Hippuran at certain radioactivity can auto sterilize themselves, whereas the positive control sample and the products diluted with non-sterile water remained unsterile. This study showed that radiopharmaceuticals have auto sterilizing properties at relatively low radioactivity, depending on the products’ bioburden. Therefore, the usual aseptic preparation of some radiopharmaceuticals can be considered terminal sterilization.
Heterologous Production of Human Papillomavirus L1 Capsid Protein: Systematic Review and Meta-analysis Andre Hendrawan; Azzania Fibriani
3BIO: Journal of Biological Science, Technology and Management Vol. 4 No. 1 (2022)
Publisher : School of Life Sciences and Technology, Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/3bio.2022.4.1.5

Abstract

The coverage of HPV vaccination in Indonesia remains low due to the high-cost vaccination. The vaccine prices were affected by the production rate of L1, the active substance of HPV vaccines. L1 has been produced using various organisms with varying L1 production rates and immunogenicity. A systematic review and meta-analysis were conducted to determine the organism producing L1 with the highest production, treatments affecting the L1 expression rate, and immunogenicity (represented by anti-L1 IgG titer in mice). The data of L1 titer, induction period, and IgG titer were extracted from 19 articles that have passed the articles screening. The L1 titer and induction period data were used to calculate the L1 production rate, while the IgG titer was used in the immunogenicity analysis. On a 95% confidence level, the meta-analysis revealed weak evidence that E. coli produced L1 at the highest rate. The highest IgG titer was induced using L1 expressed in Saccharomyces cerevisiae, albeit insufficient evidence on 95% confidence level. Pearson’s correlation analysis showed that the concentration of glucose, IPTG, NH4+, K+, Ca2+, Mn2+, Fe2+, Zn2+, B4O72−, H2PO4−, HPO42−, Mo7O246−, and citric acid had a positive correlation with L1 production rate in E. coli. The treatment injection doses positively correlated with IgG titer in S. cerevisiae. This study reveals the mineral salts as the potential treatments to increase L1 production rates.

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