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Indian Journal of Forensic Medicine & Toxicology
ISSN : -     EISSN : -     DOI : -
Core Subject : Health,
Articles 5,497 Documents
Effect of Ginger Tea on Chemotherapy-Induced Nausea and Vomiting among Patients Attending the Oncology Teaching Hospital, Baghdad 2020 Remal Adel Kadhim; Besmah Mohammed Ali; Maysaa Adel Kadhim; Samer Jassim Mohammed
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15511

Abstract

Background: Ginger has been widely used to relieve nausea and vomiting in several settings, one ofthem, patients receiving chemotherapy. This study was done to assess the effect of ginger in controlling thechemotherapy induced nausea and vomiting (CINV) among patients. Methods: An interventional (pre-post)study design was conducted in oncology teaching hospital in Baghdad for three months. Sixty participantswere randomly assigned into intervention group (30 participants received ginger tea (1.5 g/d) with routineantiemetic regimen for the first 5 days of the chemotherapy cycle) and control group (30 participants receivedonly routine antiemetic regimen). MASCC Antiemesis Tool (MAT) was used for assessment of CINV incancer patients before and after the use of ginger tea.Results: No significant difference was observed between the intervention and control groups in the acuteand delayed phases of CINV after intervention with ginger tea(p >0.05), but difference between the studygroups was found statistically significant (p <0.05)regarding the severity of nausea postchemotherapy.Conclusions: The addition of ginger tea to routine antiemetic regimen in patients receiving chemotherapyeffectively reduced the severity of nausea. However, there is no additional role for ginger in reducing theacute and delayed phases of CINV.
Development and Assessment of New Bioactive Glass Fiber Post. Part II: Ion’s Release Akram M. A. Altamimi; Manhal A. Majeed
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15512

Abstract

Objectives: This study was designed to develop and assess the ions release property of an innovativeexperimental bioactive fiber-reinforce composite as a new material for an intra-canal post.Study Design: An in vitro studyMaterials and Methods: Surface treated unidirectional E-glass fiber were impregnated and implanted witha triple cure, self-adhesive ACTIVA BioACTIVE resin cement to fabricate an experimental bioactive glassfiber post using hand lay-up moulding technique and polytetrafluoroethylene (PTFE) moulds, The cylindricaland rectangular form specimens were prepared, for each specimen, ensure 3min for self-cure setting, thenlight-cured for the 40s. The specimens were individually immersed in a deionized (DI) water, and sodiumchloride solution to assess the fluoride ion release, and calcium-phosphate ions release sequentially. VirginACTIVA BioACTIVE cement was used as a reference group for all investigations.Statistical analysis used: Statistical analysis was achieved by means of independent variable t-test, onewayANOVA, and Bonferroni Pairwise comparisons utilizing IBM-SPSS software.Results: Experimental material recognized a significant reduction in F-, Ca+2, and PO43- release afterreinforcement compared to virgin ACTIVA BioACTIVE.Conclusions: The ACTIVA BioACTIVE cement’s reinforcement process reduced the ion release intensityof the material but not affected the releasing pattern.
Isolation of Methicillin-Resistant Coagulase-Negative Staphylococci from Hemodialysis Patients in Al-Najaf Province Oday Mitib Hadi; Ihsan Khadum Humaidy
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15513

Abstract

Information about methicillin-resistant coagulase-negative staphylococci (CoNS) is unavailable in ourprovince, in comparison with methicillin-resistant Staphylococcus aureus. Two hundred and forty isolates ofStaphylococci were recovered from hemodialysis patients, from July-2019 to January-2020. Antimicrobialsusceptibility was performed for methicillin-resistant CoNS, by using the Kirby and Bauer technique.mecA gene was detected by polymerase chain reaction (PCR). The results revealed that the infections werepredominant in males (66.7%) especially in the age group more than 60 years old. Patients from urban areasoccupied the highest percent in comparison with the rural areas.Staphylococcus epidermidis was predominant among other isolated genera (63.33%), of these forty strains(26.32%) were mecA positive, while Staphylococcus saprophyticus takes only (16.67%) and six isolates wereappeared to be mecA positive. Resistant patterns illustrated that most mecA positive strains were resistant tomore than one antibiotic of none-beta lactam antibiotics especially rifampin (60.87%).In conclusion, the increase of the antibiotic-resistant by coagulase-negative staphylococci, and in particularmec A gene containing CoNS, is a risk factor for residents of the holy city of Najaf.
Effect of Zinc Supplementation on Insulin Resistance, Lipid Profile, BMI in Type II Diabetic Patients Ghusoon T. Witwit; Besmah M. Ali; Yasameen Alsaffar; Anmar D. Ghazala
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15514

Abstract

Background: Zinc is one of the most important essential trace metals in human nutrition and lifestyle withspecial role in diabetic patients mainly due to its involvement in insulin production, storage and secretion.-Objectives: to assess the effect of zinc supplementation on changing insulin resistance ,modifying lipidprofile and body mass index(BMI) in type II diabetics.-Design and Setting: A randomized controlled clinicaltrial.-Study participants: the study was carried on 50 type II diabetic patients, both gender and followed for6 weeks. the participants were randomly divided into intervention group who receives 50 mg/d elementalzinc and control group without zinc supplement.-Materials: S. zinc, fasting plasma glucose(FPG), fastingS. insulin, HbA1c, lipid profile, BMI were measured at the beginning(before supplementation and at the endof the 6 weeks duration.Results: After 6 weeks of zinc supplementation, serum zinc levels improved significantly (P=0.0001). Therewas no significant difference in BMI (P=0.092). Insulin resistance (IR), HbA1c were significantly decreased(change mean -0.75 P=0.004 and -0.72, P=0.001) respectively. HDL-C was significantly increased (changemean 3.56 mg/dl P=0.022). TG and TC were significantly decreased (change mean-10.92mg/dl P=0.001 and– 3.52mg/dl P=0.009) respectively. There was significant positive correlation between zinc intake and serumzinc level (R2=0.432).-Conclusion: Our study results revealed that supplementation of 50 mg zinc sulphateimproves insulin resistance and induces more healthy lipid profile, while it has no significant effect on BMIof type II diabetic patients after 6 weeks of supplementation.
Assessment of Neuron Specific Enolase Level and some Related Biochemical Factors in Patients with Diabetic Peripheral Nerve Disorders Zina J. Ghaib; Kadhim K. Ghudhaib; Firas Y. Mohsen
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15515

Abstract

Background: the disorder of neuron system by the action of hyperglycemia is Diabetic neuropathyconsiders a common diabetic complication which is associated with a wide scope of clinical cases. Peripheralneuropathy (PN) represents a clinical case, wherein the peripheral nervous system is damaged. Accordingly,biochemical parameters have importance to apply as good predictor factors. Accordingly we attempt toassess the biochemical factors of Neuron Specific Enolase NSE, Calpotectin CALP, Xanthine Oxidase XODin patients suffering from this type of diabetes complications as early predictors and study their correlations.Methods: Fifty eight patients are known to have diabetic mellitus, which is classified into three groups.Group I represents DPN of 30 patients, group II referred to 28 diabetic patients without DPN, in additionto 30 healthy subjects as a control group, with range age (38-70) years old. BMI was determined for all thestudied groups. Levels of FBS, lipid categories and HbA1C were estimated. NSE, CALP and XOD levelswere measured by ELISA method. hs-CRP also determine for patients and control.Results: The results revealed that levels of both FBS and HbA1C are increased significantly (p<0.05)in both patients groups rather than healthy subjects. Moreover, results recorded an important increase ofcholesterol, TGs, LDL and VLDL levels (p<0.05). in contrast the HDL decrease in the two patient groupsrelated to healthy group. Increased levels of NSE, CALP, XOD and hs-CRP in DPN group and diabeticgroup compared with control group. The results of this study showed a direct correlation between BMI andFBS, in addition to BMI and hsCRP which possess the same correlation. Analysis by ROC curve showed thatboth NSE and CALP are representing the strongest markers for diagnosis of diabetic neuropathy followedby XOD and hs-CRP respectively.Conclusion: Levels of the studied factors consider good indicators to use them as suitable markers for earlydetection of diabetic sensory neuropathy. The results of ROC curve analysis revealed that NSE and CALP isthe strongest biomarker for diagnosis of diabetic neuropathy.
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Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15517

Abstract

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Effects of Vitex Agnus Castus Leave Extract on Induced Retinal Angiogenesis in Rabbit Sara Wathiq Hadi; Shihab Abdulrahman Shihab
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15519

Abstract

Retinal pathologic angiogenesis is the leading cause of blindness in human generate from age-relatedmacular degeneration (AMD), diabetic retinopathy and premature retinopathy (ROP).The aim of this studyis to investigate the effect of vitex agnus castus leave extract on induced retinal angiogenesis in rabbitsby intravitreal injection of VEGF. Alcoholic extract of vitex agnus castus prepared and formulated forintravitreal injection. Twenty four pigmented rabbits included in this study and allocated into four equalgroups(6 rabbits in each group): Retinal angiogenesis induced group, group treated by bevacizumab, grouptreated by 100mcg of Vitex agnus castus leave extract, and group treated by 50mcg of Vitex agnus castusleave extract as intravitreal injection. Parameters include matrixmetalloproteinase-9, intracellular adhesionmolecule-1. The result of the current study revealed that intravitreal injection of Vitex agnus castus leaveextract was reduced the level of MMP-9 and ICAM-1 in comparison with retinal angiogenesis inducedgroup after one week of retinal angiogenesis induction , although it was non-significant (P>0.05).
Forensic Assessment of Genotoxic Effects of Lead Metal on leaf Phragmites australis Using Random Amplified Polymorphic DNA (RAPD-PCR) Markers Ahmed Ghalib Ibraheem; Reyam Naji Ajmi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15520

Abstract

The influence lead metal on DNA integrity in leaf plant can measure by potential effects of pollutantsaccumulation metal, Pb in leaf plant Phragmites australis was subjected to RAPD analysis, have been foundmetal at concentrations of S1, S2,S3 (0.045 , 2.97, 0.93) Respectively. polymorphisms became evident asthe presence and absence of DNA fragments in affected samples compared to effect samples. Five primewas selected OP-L05, OP-M14, OP-M20, OP-V09 and OP-M05 were used , the genomic DNA of leaf didnot appear polymorphic band at OP-L05 except molecular weight 600bp and presence of polymorphic band,OP-M20 show only polymorphic band at 850bp,OP-M05 did not show any polymorphisms and OP-M14,OP-V09 primers appeared polymorphisms when compare unexposed in control, this study confirmed RAPDmarkers a fast and simple technique can be used detection of forensic environmental.
Immunologial Study of IL32-gamma in Different Hepatitis B Virus Patient Groups at Alnajaf City Ayat Hussein Shubbar; Fahem M. D
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15521

Abstract

Hepatitis B virus is a member of the Hepadnaviridae family and responsible for causing acute and chronichepatitis in humans. This review deals with our current understanding of the virology, life cycle andimmunopathology effecting of this very important pathogen. the present study show the relationship betweenHBV infection and the rule of IL32 gamma against it ,all of which are considered essential for current andfuture approaches to antiviral treatment. The study was conducted on 159 patients [ 43(53.75%) males and37(46.25%) females] during December ,2019 to July 2020 at AL-Najaf province. They suffering from signsand symptoms of liver diseases.
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Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15523

Abstract

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