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Asian Australasian Neuro and Health Science Journal (AANHS-J)
Published by TALENTA PUBLISHER
ISSN : 26860848     EISSN : 26860848     DOI : https://doi.org/10.32734
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience
Focus and Scope Asian Australasian Neuro and Health Science Journal (AANHSJ) provides a forum for publishing the full research articles in the area of Neurosurgery and Health related to topics from the following subject areas: Neuro-Anatomy Neuro-Physiology Neuro-oncology Neuro-Spine Neuro-Pediatric Neuro-Trauma Neuro-Vascular Neuro-Fungsional Basic Science Biomoleculer in Neurology Radiology in Neurosurgery
Arjuna Subject : Kedokteran - Neurologi Klinis
Articles 99 Documents
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C2 Lesion in An Adolescent Resembling Chordoma : Histopathological Confirmation of Rheumatoid Pannus Following Two-Stage Decompression : A Case Report Arafat, Syekh Ahmad; Ibrahim, Sabri; Hakim, Muhammad 'Azmi
Asian Australasian Neuro and Health Science Journal (AANHS-J) Vol. 7 No. 01 (2025): AANHS Journal
Publisher : Talenta Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/aanhsj.v7i01.20438

Abstract

Introduction: Chordomas prevalence peaks in men around late middle age. Mostly occur in the sacrococcygeal and around base of the skull. Chordoma of the cervical spine is observed only in 6% of all chordoma, which grows slowly in size before becoming symptomatic and encase surrounding vascular and nerve structures. Case Presentation: A 17-years-old male with weakness in all extremities since 2 months with history of falling to the ground with his back landed first after somersault. After that, he began to felt numbness in all extremities. Urinary, fecal incontinence, and decrease of libido was found. Patient undergo CT scan and MRI that show canalis stenosis C2 d/t C2 Fracture Levine classification type 1A ASIA D dd spondilitis TB C2 dd susp. Pannus ec Rheumatoid arthritis. Patient underwent the occipitocervical fusion. He underwent the second operation which was trans-oral decompression and the pathology impression was chordoma. Discussion: Chordomas are a family of primary bone tumors, originate from undifferentiated embryonic notochord remnants presenting in the midline, extending throughout the skull base and axial skeleton. Only 6% of all chordoma cases mainly affect the cervical spine, as chordomas can often be found in the cervical vertebrae, either a new primary tumor or a metastatic tumor   Conclusion: Chordoma is a malignant neoplasm and if the site lesion was in the cervical spine, the chief complaint was the effect of spaced-occupying lesion in cervical, like weakness in all extremities
Functional Surgical Resection in Glioma Patients: A Literature Review on Techniques and Outcomes Barus, Brian Jovi; Sebayang, Moriko Madadoni; Ginting, Muhammad Rafif
Asian Australasian Neuro and Health Science Journal (AANHS-J) Vol. 7 No. 01 (2025): AANHS Journal
Publisher : Talenta Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/aanhsj.v7i01.20622

Abstract

Background: Gliomas frequently invade eloquent cortical and subcortical regions, necessitating surgical strategies that optimize oncological resection while preserving neurological integrity. Functional surgical resection integrates advanced modalities to achieve maximal safe resection. Method: A structured qualitative literature review was performed, synthesizing current evidence from high-impact databases on intraoperative techniques including awake craniotomy, cortical and subcortical mapping, fluorescence-guided resection, and intraoperative imaging and their impact on surgical outcomes in glioma patients. Discussion: Functional mapping and imaging adjuncts significantly improve the extent of resection and mitigate postoperative deficits, particularly in IDH-mutant low-grade gliomas and eloquent high-grade lesions. However, limitations in fluorescence efficacy, imaging resolution, and resource availability persist across institutions. Conclusion: Functional resection techniques enhance survival and quality of life by enabling individualized, anatomically precise glioma surgery. Future directions include integration of molecular diagnostics, intraoperative tools, and global standardization to reduce outcome disparities. Keyword: Glioma, Functional Surgical Resection, Awake Craniotomy, Cortical Mapping, Neuronavigation, Electrophysiological Monitoring
A Helmet Use Reduces Injury in Mild Head Trauma with Multiple Injuries: A Case Report Kailani, Dzaka Ogan Amirudin Lutfi; Hidayati, Titiek; Briliian Wahyudi, Rizqy
Asian Australasian Neuro and Health Science Journal (AANHS-J) Vol. 7 No. 02 (2025): AANHS Journal
Publisher : Talenta Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/aanhsj.v7i02.21058

Abstract

Introduction : Patients with head injuries have a high risk of organ trauma. Organ trauma can occur in conjunction with head injuries, especially in cases of accidents involving violent impact. The energy of the impact usually does not affect only one area of the body. The head may be lightly impacted, but other parts of the body may also be injured. Not all parts of the body receive the same severity of impact. The head may suffer minor injuries while other parts of the body may suffer more severe injuries. Case precentation : A 22-year-old man came to the emergency department of Yogyakarta City Hospital delivered by an ambulance with complaints of lower abdominal pain, the pain felt widespread, the patient complained of not being able to eat and drink, nausea and vomiting, left leg pain when lifted. Physical examination revealed vulnus excoriation. The diagnosis of mild head injury accompanied by multiple trauma can be established by history taking, physical examination, neurological examination, and supporting examinations such as laboratory, X-ray, and abdominal ultrasonography. Discussion : Non-helmeted riders experience more severe head and facial injuries than helmeted riders. Riders who did not wear helmets had poorer mental status than those who did, and their mean GCS scores were usually lower than those who wore helmets. This suggests that there is a relationship between head protection, or helmets, and the severity of motorcyclists' injuries, and that when motorcyclists do not wear helmets, injuries and the risk of injury are greater. Conclusion : The patient suffered a mild head injury with multiple organ trauma after physical and supporting examinations. The patient's head injury can be minimized because the patient was still wearing a helmet at the time of the accident.
Efficacy of Endoscopic Lumbar Discectomy in Motor Deficit Recovery: A Meta-Analysis of Neurological and Functional Outcomes Ibrahim, Sabri; Rasyid, Fahmi
Asian Australasian Neuro and Health Science Journal (AANHS-J) Vol. 7 No. 02 (2025): AANHS Journal
Publisher : Talenta Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/aanhsj.v7i02.21661

Abstract

Background: Endoscopic Lumbar Discectomy (ELD) has gained popularity as a minimally invasive alternative for treating lumbar disc herniation. However, its safety and efficacy in patients with preoperative motor deficits remain under debate due to concerns about limited decompression and neurological recovery. This study aimed to evaluate neurological and functional outcomes following ELD in patients presenting with motor weakness. Methods: A meta-analysis were conducted on studies published between 2015 and 2025. Databases searched included PubMed, Scopus, Web of Science, and Cochrane Library. Eligible studies reported pre- and postoperative motor function (MRC scale) and/or functional disability (Oswestry Disability Index, ODI) in patients undergoing ELD. Pooled mean changes in MRC and ODI were calculated, and subgroup analysis was performed based on baseline motor strength. Results: Eight studies comprising 613 patients met inclusion criteria. The pooled mean improvement in motor strength was +1.44 on the MRC scale. Functional outcomes improved significantly, with a mean ODI reduction of −37.3 points. Patients with severe baseline deficits (MRC ≤3) demonstrated greater neurological recovery. No study reported postoperative motor deterioration, and complication rates were low. Conclusion: ELD is associated with favorable neurological and functional outcomes in patients with preoperative motor deficits. These findings suggest that motor weakness should not be considered a contraindication to ELD, and with appropriate selection and expertise, ELD offers a safe and effective surgical option.
The Arteriovenous Malformation Rupture on Posterior Cranial Fossa:Management and Treatment of 9 Children Patients at Morozovskaya Children's Hospital: Arteriovenous Malformation Rupture on Posterior Cranial Fossa:Management Zokirjon Utkurovich, Zokhidov; Encarnacion-Santos, Daniel; Chmutin, Gennady; Gordon-Gullanyi, Ayisi; Chmutin, Egor; Livshits , Matvey Igorevich; Levov , Alexander Vyacheslavovich; Berdieva , Madina Golibovna; Shlepotina, Elizaveta Andreevna; Dovran, B. Nurmyradov; Mamatkulov , Sherbek Musakulovich
Asian Australasian Neuro and Health Science Journal (AANHS-J) Vol. 7 No. 02 (2025): AANHS Journal
Publisher : Talenta Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/aanhsj.v7i02.22492

Abstract

Abstract Background Posterior cranial fossa (PCF) arteriovenous malformations (AVM) in children are the least studied among vascular malformations. Mortality rates after hemorrhages from ruptured PCF AVM reach the range of up to 21-67%. The aim of this Evaluation of the treatment tactics of the arteriovenous malformation rupture in an area of the posterior cranial fossa in children. Materials and Methods The study includes 9 children admitted to the Morozovskaya Children’s City Clinical Hospital Moscow Healthcare department, Moscow, Russia, with PCF, AVM intracranial hemorrhage (ICH) during the period of 2015-2022. The age varies from 7 to 17 years old. All patients underwent clinical and neurological examination, CT, and MRI of the brain, as well as cerebral angiography. The volume of intracranial hematoma ranges from 5 to 41.1 mL. To decide on the further extent of surgical intervention, GCS, Greab, PedNIHSS, and H-H scales were used. Results The extent of surgical intervention was based on the time of the admission to the hospital, the severity of the patients’ condition, the size and location of the ICH, and its relationship to the med-stem structures. Type of operation: microsurgical intervention in 3 cases (33.3 %), endovascular embolization in 2 cases (22.2 %), combined treatment in 4 cases (44.5 %). Surgery was performed in the acute period in all patients. Conclusion Modern microsurgical and endovascular PCF AVM treatment methods allow for positive results in complete neurological symptom regression form. This considerably decreases disability rates and increases patients’ quality of life.
Global Ischemic in A 3-Months-Old Child with Hydrocephalus : A Case Report of Good Outcome Ahmad Arafat, Syekh; Rasyid Sihombing, Fahmi; Ihsan Z. Tala, Muhammad; Mouza, Abdurrahman
Asian Australasian Neuro and Health Science Journal (AANHS-J) Vol. 7 No. 03 (2025): AANHS Journal
Publisher : Talenta Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/aanhs-j.v7i03.20427

Abstract

Introduction. Ventriculomegaly causes compression within the cranial vault, which increases intracranial pressure and leads to severe brain damage. Usually progressive. if untreated, may be fatal. Case. 3-month-old male child with increasement of head circumference for 2 months. Fever, cough, cold, vomiting, seizure was not found. MRI show extensive dilatation of ventricular system wide-open foramen of Luschka and Magendie with thinning of cerebral cortex and also global ischemic hypoxia. Discussion. The CBF is regulated by the Monroe-Kellie doctrine which state that space of the cranial cavity is fixed in volume. Congenital hydrocephalus occurs in one in 500-1000 babies born in the United States. Lipid peroxides, formed by oxygen free radical damage to membranes, have been detected in hydrocephalic brains by detection of thiobarbituric acid reactive substances. The mechanism of periventricular axon damage includes calcium mediated activation of proteolytic calpains that damage cytoskeletal proteins, similar to the processes that follow acute traumatic or ischemic injury. The gold standard permanent treatment for hydrocephalus is CSF diversion by placement of a shunt. A shunt has three basic component parts: a ventricular catheter placed in the lateral ventricle, a valve regulating the flow of CSF out of the brain, and a distal catheter that terminates in a cavity. The most common shunt, a ventriculoperitoneal shunt (VPS), has been well accepted since its inaugural use. Surgical treatment is associated with a 50% reduced risk of death overall
The Cervical Spinal Epiduritis, pertaining to Diagnosis, Treatment, and Outcomes: on severe spinal cord stenosis. A Case Report and a Literature Review: Cervical Spinal Epiduritis, pertaining to Diagnosis, Treatment, and Outcomes Encarnacion-Santos, Daniel; Shestov, Eugeny; Pachev, Murat; Chmutin, Gennady; Chmutin, Egor; Rubenovich-Chikava, Dmitriy; Axenova, Marina; Chaurasia, Bipin
Asian Australasian Neuro and Health Science Journal (AANHS-J) Vol. 7 No. 03 (2025): AANHS Journal
Publisher : Talenta Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/aanhs-j.v7i03.22830

Abstract

Abstract Background: Osteomyelitis coupled with immunocompromised people with drug or intravenous drug use produces infective endocarditis. Remember that atlantoaxial subluxation accompanied by infection of the pharynx or nearby tissues is termed Grisel syndrome. [2]. Epidural abscesses are sometimes surgical emergencies, depending on the type of neurological impairments. An upper cervical epidural abscess in the occiput at the level of C2 is highly rare and uncommon. At the level of the subaxial spine at C3-C6 OR C7-T1 is the cervicothoracic area. Case Presentation A 54-year-old female patient reported experiencing cough and catarrhal symptoms for three months due to a previous coronavirus infection, accompanied by shortness of breath and joint pain. The patient's neck pain intensified, radiating to the left arm (myelopathy); conservative treatment was ineffective. MRI of the cervical spine indicated purulent spondyloarthritis affecting the left C4-C6 facet joints, with severe spinal cord stenosis (Figure 1), accompanied by epiduritis in the adjacent segment and abscess formation in the posterior paravertebral muscles of the neck. The surgical intervention consisted of a left C5-C6 hemilaminectomy with a microdiscectomy with which a metal cage was placed after sanitation and drainage of the purulent epiduritis, approach to the spondyloarthritis in the C4-C6 segments, and management of an intermuscular abscess with a cage. Conclusion Our clinical case shows a cervical spinal epiduritis with spinal cord stenosis, confirmed by imaging; therefore, once the diagnosis was confirmed, the decision was to perform an eminent surgical intervention with a hemilaminectomy and microdiscectomy.
Characteristics of Neonatal Intracranial Hemorrhage at RSUP Haji Adam Malik during the Year 2022-April 2025 Alma Cahyadi, Caroline; Mousa, Abdurrahman; Muhadi Rangkuti, Deske; Yunita, Rina
Asian Australasian Neuro and Health Science Journal (AANHS-J) Vol. 7 No. 03 (2025): AANHS Journal
Publisher : Talenta Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/aanhs-j.v7i03.24097

Abstract

The neonatal state is a vulnerable period where rapid physiological transitions happen. In Indonesia, in the year 2020, the Infant Mortality Rate was 19.83 per 1,000 live births, including a Neonatal Mortality Rate of 9.30. This state is also a part of the critical period of a postnatal brain development. Disruption to the brain during this time window can cause problems in the neurodevelopmental process. One of the examples being intracranial hemorrhage in neonates, which the true prevalence and incidence rates of are unclear, but which have high mortality and morbidity rates. The objective this study is to determine the characteristics of neonatal intracranial hemorrhage at Haji Adam Malik General Hospital in 2022-April 2025. This study used a descriptive design through a retrospective cross-sectional study and a sample of neonates with intracranial hemorrhage at Haji Adam Malik General Hospital through saturated sampling. It was found that incidence rate was 6.24 per 100, with the most common bleeding location being intraventricular 25 (89.3%), the majority of neonates were premature, namely 19 (67.9%), low birth weight 19 (67.9%), the most common symptoms were seizures and respiratory distress 15 (53.6%), and 11 (39.3%) neonates made a good recovery.
Bilateral Stromal Corneal Dystrophy Mimicking Central Visual Pathway Dysfunction: A Case Report Imania; El Emir, Newi
Asian Australasian Neuro and Health Science Journal (AANHS-J) Vol. 7 No. 03 (2025): AANHS Journal
Publisher : Talenta Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/aanhs-j.v7i03.24307

Abstract

Progressive bilateral visual loss is a clinical red flag that frequently prompts evaluation for intracranial lesions involving the optic nerves, chiasm, or retrochiasmal pathways. However, anterior segment disorders such as corneal dystrophies may mimic central visual pathway pathology, especially when visual acuity loss occurs without overt ocular pain or inflammation. We report the case of a 31-year-old male presenting with progressive, symmetric visual impairment initially suspected to be neurologic in origin. Slit-lamp examination revealed bilateral mid-stromal crystalline opacities consistent with stromal corneal dystrophy. The absence of afferent pupillary defects, normal fundus findings, and lack of neurologic signs further supported a corneal etiology. This case illustrates the diagnostic challenge of distinguishing anterior segment disease from true neuro-ophthalmologic conditions. Failure to recognize corneal dystrophy may result in unnecessary neuroimaging and delayed treatment. Clinicians assessing bilateral vision loss, particularly in young adults, must include detailed anterior segment evaluation in their diagnostic algorithm to prevent mislocalization of pathology and ensure accurate management. Keyword: Cornea, corneal dystrophy, bilateral visual loss, neuro-ophthalmology, keratoplasty

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