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Jurnal Ilmiah Kesehatan (JIKA)
Published by Sarana Ilmu Indonesia
ISSN : 23379847     EISSN : 26862883     DOI : https://doi.org/10.36590/jika
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health
Jurnal Ilmiah Kesehatan (JIKA) aims to provide forum exchanges and interfaces between researchers and related practitioners in the field of health. The journal only accepts articles from original research results (top priorities), case study articles (not priorities), and scientific studies of recent articles (not preferences). JIKA is a scientific journal that contains research papers from the field of health sciences including: Medical and clinical research, food and nutrition research, public health research, obstetrics management research, nursing management research, and pharmacy research.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 341 Documents
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Multiple Micronutrient Supplementation on Hemoglobin Levels among Second-Trimester Pregnant Women Munazah Alya Zavirah; Reny Retnaningsih; Sulistiyah Sulistiyah
Jurnal Ilmiah Kesehatan (JIKA) Vol. 8 No. 2 (2026): Volume 8 Nomor 2 Agustus 2026
Publisher : Sarana Ilmu Indonesia (Salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v8i2.2090

Abstract

Anemia during pregnancy remains a major maternal health concern, particularly in the second-trimester when physiological hemodilution may reduce hemoglobin levels. Iron-folic acid (IFA) supplementation is the standard intervention for preventing and treating maternal anemia; however, multiple micronutrient supplementation (MMS) has been proposed as a potentially more comprehensive approach due to its broader nutrient content. This study aimed to compare the effectiveness of MMS and IFA in improving hemoglobin levels among second-trimester pregnant women. A quasi-experimental pretest-posttest non-equivalent control group design was conducted among 34 pregnant women. Participants were selected using purposive sampling and assigned to either the MMS group (n=17) or the IFA group (n=17). Hemoglobin levels were measured before and after the intervention using the EasyTouch GCHb point-of-care device. Data were analyzed using paired t-tests and independent t-test/Welch’s t-test with a significance level of 0.05. Baseline hemoglobin levels were similar in both groups (9.82 g/dL). Following the intervention, mean hemoglobin levels increased to 10.47 g/dL in the IFA group and 11.38 g/dL in the MMS group. The mean increase in hemoglobin was significantly greater in the MMS group (1.56±0.59 g/dL) compared with the IFA group (0.65±0.05 g/dL), with a between-group difference of 0.91 g/dL (95% CI 0.61–1.21; p < 0.001; Hedges' g = 2.14). MMS was significantly more effective than IFA in increasing hemoglobin levels among second-trimester pregnant women. These findings suggest that MMS may provide greater benefits in addressing maternal anemia during pregnancy.

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