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Jurnal Klinik dan Riset Kesehatan (Journal of Clinical and Health Research) Bidang Pendidikan dan Penelitian, RSUD dr. Saiful Anwar Malang Jl. Jaksa Agung No. 2, Kec. Klojen, Malang 65112 Phone/Fax: 0341 – 362101 / 0341 - 369384 Email: jkrisk.rssa@gmail.com
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INDONESIA
Jurnal Klinik dan Riset Kesehatan
Published by RSUD Dr. Saiful Anwar Malang
ISSN : 28092678     EISSN : 28090039     DOI : https://doi.org/10.11594/jk-risk
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health
Jurnal Klinik dan Riset Kesehatan (JK-RISK) – RSUD dr. Saiful Anwar Malang adalah jurnal open-access resmi yang dikelola oleh tim Penelitian dan Pendidikan Rumah Sakit Umum Daerah dr. Saiful Anwar Malang, Jawa Timur, Indonesia. JK-RISK menerbitkan satu volume yang terdiri atas tiga nomor setiap tahunnya yang diterbitkan pada bulan Oktober, Februari, dan Juni. JK-RISK hanya akan menerbitkan jurnal berbahasa Indonesia. Jurnal Klinik dan Riset Kesehatan – RSUD dr. Saiful Anwar Malang menerbitkan tulisan-tulisan ilmiah hasil penelitian, laporan kasus, tinjauan pustaka dalam bidang kedokteran dan kesehatan yang belum pernah diterbikan di jurnal manapun. Pernyataan kode etik publikasi JK-RISK merupakan pernyataan kode etik yang melibatkan pengelola jurnal, editor, mitra bestari serta penulis dalam proses publikasi jurnal ilmiah. Pernyataan kode etik didasarkan pada Peraturan Kepala LIPI Nomor 5 tahun 2014 tentang Kode Etik Publikasi Ilmiah yang menjunjung tinggi tiga nilai etik dalam publikasi, yaitu (i) Kenetralan, yang berarti terbebas dari pertentangan kepentingan dalam pengelolaan publikasi jurnal; (ii) Keadilan, dengan memberikan kebebasan hak kepengarangan kepada pengarang/penulis; dan (iii) Kejujuran, yang berarti bebas dari duplikasi, fabrikasi, falsifikasi dan plagiarisme (DF2P) dalam publikasi.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 18 Documents
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Search results for , issue "Vol 4 No 2 (2025): Edisi Februari" : 18 Documents clear
Progression Free Survival pada Pasien Kanker Paru Adenokarsinoma Wild Type dengan Kombinasi Regimen Pemetrexed dengan Cisplatin dibandingkan dengan Karboplatin Agus Setyawan, Ungky; Purnamawati, Catur; Pratiwi, Suryanti
Jurnal Klinik dan Riset Kesehatan Vol 4 No 2 (2025): Edisi Februari
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.2.2

Abstract

Pendahuluan: Progression-free survival (PFS) adalah parameter untuk mengukur perkembangan kanker paru adenokarsinoma wild type. Berbagai studi literatur telah menunjukkan bahwa kombinasi kemoterapi berbasis platinum-pemetreksed lebih efektif untuk progresivitas adenokarsinoma wild type yang berkepanjangan. Tujuan: Tujuan penelitian ini membandingkan PSF pasien adenokarsinoma wild type yang mendapat rejimen sisplatin-pemetreksed dan karboplatin-pemetreksed di Rumah Sakit Dr. Saiful Anwar tahun 2018-2021. Metode: Penelitian kohort retrospektif berdasarkan medical record pasien adenokarsinoma wild type. Hasil: Hasil penelitian menunjukkan bahwa pemberian rejimen karboplatin-pemetreksed memiliki PFS yang lebih panjang (median 4 bulan, 95% CI 2.657-5.343) dibandingkan dengan sisplatin-pemetreksed (median 2 bulan, 95% CI 0.988-3.012). Selain itu risiko progresivitas kanker paru berdasarkan PFS tidak dipengaruhi secara signifikan oleh nilai skala Karnofsky 70-80 (72,2%, HR 0,278). Sebaliknya, riwayat merokok meningkatkan risiko progresivitas kanker paru, walaupun tidak berpengaruh secara signifikan (HR 1.538). Kesimpulan: Pemberian rejimen karboplatin-pemetreksed memperpanjang PFS hingga 10-16 bulan, meskipun tidak ada perbedaan yang signifikan secara statistik bila dibandingkan dengan sisplatin-pemetreksed.
Profil Program Fisioterapi pada Pasien Stroke Berdasarkan NIHSS di Rawat Inap RSUD Dr. Saiful Anwar Malang pada Januari-Maret 2023 Izzati, Fatma; Setianto, Catur
Jurnal Klinik dan Riset Kesehatan Vol 4 No 2 (2025): Edisi Februari
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.2.3

Abstract

Pendahuluan: Stroke merupakan salah satu penyebab disabilitas tertinggi di dunia. Indonesia sudah memiliki pedoman rehabilitasi stroke, tetapi implementasi pedoman tersebut di rumah sakit di Indonesia jarang diteliti. Tujuan: Penelitian ini bertujuan mengetahui profil program fisioterapi pada pasien stroke pasca fase akut yang dirawat inap di RSUD Dr. Saiful Anwar Malang pada Januari-Maret 2023 berdasarkan National Institutes of Health Stroke Scale (NIHSS). Metode: Studi menggunakan metode deskriptif-kuantitatif. Data diambil dari rekam medis elektronik RSUD Dr. Saiful Anwar Malang pada Januari-Maret 2023. Hasil: Didapatkan 129 pasien stroke yang memenuhi kriteria inklusi, terdiri dari 56,6 % pria dan 43,4% wanita, dengan rentang usia terbanyak 51-60 tahun (34,88%). Tingkat keparahan stroke terbanyak adalah stroke berat (NIHSS 21-42) sebanyak 34,88%, kemudian stroke sedang (NIHSS 5-15) 31,01%, stroke sedang-berat (NIHSS 16-20) 19,38%, dan stroke ringan (NIHSS 1-4) 14,73%. Hampir semua pasien dalam semua tingkat keparahan mendapatkan program proper positioning, mobilisasi bertahap, dan terapi fisik dada (persentase terkecil 73,68% pada stroke ringan). Selain tiga intervensi tersebut, pada stroke ringan, intervensi rehabilitasi yang diberikan paling banyak adalah AAROM exercise (57,89%), pada stroke sedang adalah AROM exercise (62,5%), pada stroke sedang-berat adalah PROM exercise (72%), pada stroke berat adalah PROM exercise. Kesimpulan: Semua pasien stroke pada semua tingkat keparahan mendapatkan proper positioning, mobilisasi bertahap, dan rehabilitasi fisik dada, tetapi program fisioterapi motorik, sensorik, kognitif, dan lain-lain pada pasien berbeda tergantung tingkat keparahan.
Peran Latihan Disupervisi pada Pasien dengan Penyakit Arteri Perifer Eksremitas Bawah Lestari, Defyna; Tjahjono, Cholid
Jurnal Klinik dan Riset Kesehatan Vol 4 No 2 (2025): Edisi Februari
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.2.6

Abstract

Peripheral arterial disease is a disorder caused by decreased blood flow to the extremities. The process of atherosclerosis generally causes it and manifests as claudication. In addition to optimal medical and endovascular therapy, non-pharmacological management of PAP has been proven to be effective in reducing symptoms and improving walking ability and quality of life. Walking exercise can increase blood flow, which allows oxygen and nutrients to reach the muscles more efficiently and triggers the angiogenesis process. Supervised exercise programs in PAP patients are considered important as primary therapy to improve functional capacity and quality of life for long-term management.
Penundaan Stent pada Beban Trombus Tinggi: Sebuah Laporan Kasus Kurniawan, Catur; Widito, Sasmojo; Putri, V.Y.S
Jurnal Klinik dan Riset Kesehatan Vol 4 No 2 (2025): Edisi Februari
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.2.8

Abstract

Direct stent implantation is widely recommended for the management of patients who have acute myocardial infarction with ST-segment elevation. However, in situations where there is HTB in the affected artery, stenting may increase the risk of no flow phenomenon. Delaying stenting may reduce complications. A 45-year-old man presented with symptoms suggestive of acute right ventricular infarction that started 8 hours before admission. The patient underwent an echocardiogram which showed an ejection fraction of 36%. Pre-PCI pharmacotherapy was administered. Coronary angiography showed a grade IV occlusion in the mid-LAD branch as well as a thrombus in the mid-RCA with TIMI 2 flow. Thrombus aspiration and balloon inflation were performed, but HTB persisted. DS was decided, with additional Enoxaparin 0. 6 cc twice daily. Subsequent angiography after 34 hours, showed CAD in three coronary artery branches with the RCA still showing complete occlusion with HTB. A stent implantation procedure was performed in the mid-RCA segment The final result achieved was TIMI 3 blood flow, with no residual stenosis. HTB can also be diagnosed based on the TIMI thrombus risk classification. The main goal of deferred stenting is to minimize complications such as the slow-flow phenomenon of distal embolization. It is important to emphasize that a routine DS strategy has not shown clear benefit and is not recommended.
Diagnosis dan Manajemen Obstruksi Jalan Napas Atas (Jackson 1) Akibat Infeksi Difteri pada Wanita Hamil Dwikarlina, Intan; Wijaya, Rendy; Yulia Rusmayanti, Mega; Antariksa, Genta; Candradikusuma, Didi
Jurnal Klinik dan Riset Kesehatan Vol 4 No 2 (2025): Edisi Februari
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.2.9

Abstract

Diphtheria is an infectious disease caused by Corynebacterium diphtheria, which generally causes inflammation of the airways, leading to severe symptoms that can be life-threatening. Indonesia is listed as one of the ten countries with the highest cases of diphtheria worldwide. However, studies on cases of diphtheria infection, especially in the pregnant women population, have rarely been reported. A 28-year-old woman presented with shortness of breath. Complaints accompanied by difficulty swallowing and speaking. The patient had a child who died due to similar symptoms. Signs of airway obstruction are found as inspiratory stridor and suprasternal retraction, pseudomembranes in the pharynx, and subcutaneous crepitation in the colli. Diphtheria infection was confirmed through a throat swab examination with Neisser staining and culture. In addition to isolation, the patients were administered oxygen therapy, anti-diphtheria toxin, penicillin procaine, dexamethasone, and additional supportive therapy. Diphtheria infection is transmitted through direct contact, droplets or contaminated items. Manifestations of laryngeal diphtheria generally come from the extension of tonsillar-pharyngeal diphtheria symptoms, including sore throat, hoarseness, and advanced respiratory obstruction. A definite diagnosis is made by isolating the bacteria or finding an increase in serum antibodies. Therapies targeting infectious conditions and supporting obstetrics help improve the overall patient condition. Diphtheria is a highly contagious and potentially fatal disease, especially for pregnant women; thus, immediate diagnosis is needed. Isolation and appropriate management alleviate upper airway obstruction. Diphtheria management should include both curative therapy and preventive to protect the community further and prevent outbreaks from emerging.
Hubungan Kadar Trombosit dengan Gambaran Luas Lesi Tuberkulosis Paru melalui Foto Chest X-Ray Alimsjah, Yohanes Audric; Yueniwati, Yuyun; Nugroho, Rafiq Sulistyo
Jurnal Klinik dan Riset Kesehatan Vol 4 No 2 (2025): Edisi Februari
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.2.4

Abstract

Background: Pulmonary tuberculosis (TB) is a chronic inflammatory disease accompanied by changes in particular haematological parameters within the blood. The changes in the composition of blood cells can be potential biomarkers to assist tuberculosis diagnosis beside using clinical, microbiological, and radiological tools. Platelets play a vital part in chronic inflammation since they contain different sorts of mediators that are involved in lung damage which is reflected in the extent of lesions on radiological examination. Aim: The research aims to compare the platelets level between minimal/moderate versus extensive lesions in the patient with TB. Methods: The research was a retrospective, cross-sectional study of patients with pulmonary tuberculosis who were treated at Saiful Anwar Hospital from January 2022 to December 2023. The results of the research were analyzed using the Chi-Square method. Results: Patients with extensive pulmonary TB lesions have platelet levels that tend to be high, in contrast to patients with minimal/moderate pulmonary TB lesions tend to have low platelet levels. Conclusion: There was a significant relationship between platelet levels and the extent of pulmonary tuberculosis lesions.
Risiko Kardiovaskular pada Terapi Radiasi: Tinjauan Klinis tentang Penyakit Jantung yang Diinduksi oleh Radiasi Widhianto, Andre Tegar
Jurnal Klinik dan Riset Kesehatan Vol 4 No 2 (2025): Edisi Februari
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.2.5

Abstract

Radiotherapy, which has become a pivotal part of cancer treatment over the past 50 years, has indeed proven to increase patient cure rates. However, despite its success, radiotherapy also carries inevitable side effects on the cardiovascular system, specifi­cally radiation-induced heart disease (RIHD). RIHD encompasses a variety of heart diseases, including pericardial disease, coronary artery disease, valvular heart disease, conduction system abnormalities, cardiomyopathy, and vascular disease of medium or large vessels. These side effects can result from the direct impact of radiation on the function and structure of the heart or by accelerating the progression of pre-existing cardiovascular diseases, especially in patients with prior cardiovascular risk factors. Scientists have now developed non-invasive methods to detect RIHD. Additionally, vari­ous efforts are being made to prevent and minimize RIHD. This review delves deeper into the pathogenesis, clinical manifestations, diagnosis, management, and prevention of RIHD.
Modalitas Pencitraan Non Invasif pada Sindroma Koroner Kronis Indrihapsari, Pratiwi; Widito, Sasmojo
Jurnal Klinik dan Riset Kesehatan Vol 4 No 2 (2025): Edisi Februari
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.2.7

Abstract

Advancements in non-invasive cardiovascular imaging technology have introduced robust diagnostic modalities for managing cardiovascular diseases. Three prominent techniques in this domain are stress echocardiography, coronary computed tomography angiography (CCTA), cardiac magnetic resonance imaging (CMR), Single Photon Emission Computed Tomography (SPECT), and Positron Emission Tomography (PET). These modalities provide crucial information for accurate diagnosis and optimal therapeutic planning. Stress echocardiography occupies a strategic position in the diagnostic algorithm, particularly in suspected or confirmed cases of coronary artery disease. The strength of this modality lies in its ability to provide a comprehensive picture of myocardial functional status. Meanwhile, CCTA offers superiority in visualizing and characterizing atherosclerotic plaques in coronary vessels, enabling early detection and more precise risk stratification. This literature review aims to explore critical aspects of non-invasive cardiovascular imaging modalities in the context of diagnosing Chronic Coronary Syndrome.
Masa Depan Manajemen Penyakit Kronis Transformasi Tren Baru dari Diagnosis hingga Rehabilitasi Fatma, Siti
Jurnal Klinik dan Riset Kesehatan Vol 4 No 2 (2025): Edisi Februari
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.2.1

Abstract

Progression Free Survival pada Pasien Kanker Paru Adenokarsinoma Wild Type dengan Kombinasi Regimen Pemetrexed dengan Cisplatin dibandingkan dengan Karboplatin Agus Setyawan, Ungky; Purnamawati, Catur; Pratiwi, Suryanti
Jurnal Klinik dan Riset Kesehatan Vol 4 No 2 (2025): Edisi Februari
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.2.2

Abstract

Background: Progression-free survival (PFS) is a parameter to measures the progression of wild type adenocarcinoma lung cancer. Literature studies have shown that the combination platinum based-pemetrexed chemotherapy is more effective to prolonged progressivity of wild type adenocarcinoma. Aim: The aim of study to compared the PSF of wild type adenocarcinoma patients receiving cisplatin-pemetrexed and pemetrexed-carboplatin regimens at Dr. Saiful Anwar Hospital in 2018-2021. Methods: A retrospective cohort study based on medical record of wild type adenocarcinoma patients. Results: The results showed that the administration of a carboplatin-pemetrexed regimen has prolonged PFS (median 4 months, 95% CI 2.657-5.343) compared to the cisplatin-pemetrexed regimen (median 2 months, 95% CI 0.988-3.012). In addition, the risk of lung cancer progression based on PFS is not significantly influenced by the Karnofsky scale value of 70-80 (72.2%, HR 0.278). On the other hand, a history of smoking increases the risk of lung cancer progression, although it does not have a significant effect (HR 1,538). Conclusion: Administration of the carboplatin-pemetrexed regimen prolongs PFS up to a range of 10-16 months, although there is no statistically significant difference compared to the cisplatin-pemetrexed.

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