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All Journal Jurnal Klinik dan Riset Kesehatan Journal of Community Health and Preventive Medicine (JOCHAPM)
Agus Setyawan, Ungky
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Biochemistry, Genetics & Molecular Biology Environmental Science Health Professions Medicine & Pharmacology Nursing Public Health

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Karakteristik Faal Paru Berdasarkan Pemeriksaan Spirometri pada Pasien Suspek Tumor Paru dan Mediastinum Pratiwi, Suryanti; Agus Setyawan, Ungky; Listyoko, Aditya; Kirana, Intan
Jurnal Klinik dan Riset Kesehatan Vol 1 No 3 (2022): Edisi Juni
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.01.3.3

Abstract

Pendahuluan: Keganasan paru merupakan penyakit paru yang memiliki tingkat kematian tertinggi di dunia. Pemeriksaan untuk mengetahui fungsi paru dengan menggunakan spirometri. Tujuan: Penelitian ini bertujuan untuk mengetahui distribusi faal paru pasien dengan diagnosis suspek tumor paru dan mediastinum di Rumah Sakit Saiful Anwar (RSSA) Malang berdasarkan usia, jenis kelamin, indeks massa tubuh (IMT), dan diagnosis. Metode: Penelitian deskriptif analitik, pendekatan cross-sectional dengan menggunakan data rekam medis Januari 2018 – Desember 2019 kemudian dilakukan uji spearman. Hasil: Hasil penelitian menunjukkan diagnosis suspek tumor paru dan mediastinum paling banyak pada rentang usia 51-60 tahun, jenis kelamin terbanyak laki-laki, diagnosis terbanyak tumor paru. Hasil interpretasi pemeriksaan spirometri terbanyak menunjukkan restriksi, dan IMT normal. Hasil analisis hubungan gambaran faal paru memiliki p-value pada suspek tumor paru dan mediastinum (0,814), jenis kelamin (0,003), dan IMT (0,360). Kesimpulan: Terdapat hubungan yang signifikan antara gambaran faal paru dengan jenis kelamin dan tidak didapatkan hubungan yang signifikan antara gambaran faal paru dengan diagnosis dan IMT.
THE RELATIONSHIP BETWEEN THE LEVEL OF KNOWLEDGE ABOUT THE DANGERS OF CIGARETTES AND CARBON MONOXIDE LEVELS OF BREATHING AIR IN STUDENTS FROM A HIGH SCHOOL IN MALANG Dwi Pratiwi, Suryanti; Agus Setyawan, Ungky; Mafisah, Saidah; Muhammad, Iqbal; Herda Asyari, Claudia; Dini, Zata; Pratiwi, Eka; Lyono, Albert; Delfianto, Dwiroza Delfianto; Nur Hikmah, Naila Nur Hikmah; Suardana, I Made Suardana; Martha , Martha
Journal of Community Health and Preventive Medicine Vol. 4 No. 2 (2024): JOCHAPM Vol. 4 No. 2 2024
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jochapm.2024.004.02.3

Abstract

This study aims to analyze the relationship between the level of knowledge about the dangers of smoking and smoking behavior and exposure to cigarette smoke in high school students. This quantitative descriptive research with a cross-sectional design involved 114 students from one Malang Senior High School, with sampling using a simple random sampling method. Using a CO analyzer, data was collected through questionnaires to measure students' knowledge levels and measurements of carbon monoxide (CO) in breathing air. The study results showed that 62% of the respondents were women and 38% were men, with an average age of 16.8 years. As many as 80% of students do not smoke, while the other 20% are active smokers. The average CO level of the students' breath air was 3.34 PPM, with active smokers showing significantly higher CO levels (7.74 PPM) compared to passive smokers (2.06 PPM) and non-smoking students (2.61 PPM). The ANOVA statistical test showed a significant difference in CO levels between groups (p < 0.05). Although the level of students' knowledge about the dangers of smoking was relatively high (average pretest 124), no significant relationship was found between knowledge and smoking behavior (p = 0.802). The study concluded that although knowledge about the dangers of smoking is moderate, smoking behavior among male students remains high, suggesting the need for more in-depth interventions to address the social and psychological factors that support smoking behavior.
Progression Free Survival pada Pasien Kanker Paru Adenokarsinoma Wild Type dengan Kombinasi Regimen Pemetrexed dengan Cisplatin dibandingkan dengan Karboplatin Agus Setyawan, Ungky; Purnamawati, Catur; Pratiwi, Suryanti
Jurnal Klinik dan Riset Kesehatan Vol 4 No 2 (2025): Edisi Februari
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.2.2

Abstract

Pendahuluan: Progression-free survival (PFS) adalah parameter untuk mengukur perkembangan kanker paru adenokarsinoma wild type. Berbagai studi literatur telah menunjukkan bahwa kombinasi kemoterapi berbasis platinum-pemetreksed lebih efektif untuk progresivitas adenokarsinoma wild type yang berkepanjangan. Tujuan: Tujuan penelitian ini membandingkan PSF pasien adenokarsinoma wild type yang mendapat rejimen sisplatin-pemetreksed dan karboplatin-pemetreksed di Rumah Sakit Dr. Saiful Anwar tahun 2018-2021. Metode: Penelitian kohort retrospektif berdasarkan medical record pasien adenokarsinoma wild type. Hasil: Hasil penelitian menunjukkan bahwa pemberian rejimen karboplatin-pemetreksed memiliki PFS yang lebih panjang (median 4 bulan, 95% CI 2.657-5.343) dibandingkan dengan sisplatin-pemetreksed (median 2 bulan, 95% CI 0.988-3.012). Selain itu risiko progresivitas kanker paru berdasarkan PFS tidak dipengaruhi secara signifikan oleh nilai skala Karnofsky 70-80 (72,2%, HR 0,278). Sebaliknya, riwayat merokok meningkatkan risiko progresivitas kanker paru, walaupun tidak berpengaruh secara signifikan (HR 1.538). Kesimpulan: Pemberian rejimen karboplatin-pemetreksed memperpanjang PFS hingga 10-16 bulan, meskipun tidak ada perbedaan yang signifikan secara statistik bila dibandingkan dengan sisplatin-pemetreksed.
Karakteristik Faal Paru Berdasarkan Pemeriksaan Spirometri pada Pasien Suspek Tumor Paru dan Mediastinum Pratiwi, Suryanti; Agus Setyawan, Ungky; Listyoko, Aditya; Kirana, Intan
Jurnal Klinik dan Riset Kesehatan Vol 1 No 3 (2022): Edisi Juni
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.01.3.3

Abstract

Background: Lung malignancy is a lung disease that has the highest mortality rate in the world. An examination to determine the state of lung function is spirometry. Aim: This study aims to determine the distribution of lung function in patients with suspect of lung and mediastinal tumor at Saiful Anwar Hospital Malang based on age, sex, body mass index (BMI), and diagnosis. Methods: This research is a descriptive analytic, cross-sectional approach using medical record data from January 2018 to December 2019 and then the data would be processed by spearman test. Results: The results showed that patients with suspect lung and mediastinal tumors suffered the most in the age range of 51-60 years, the sexes were mostly male, the most diagnoses were lung tumors. Most of the interpretation results of the spirometry examination showed restriction, and normal body mass index. The results of the analysis of the relationship between pulmonary function descriptions had a p-value of 0.814 for diagnosis of suspected lung and mediastinal tumor, 0.003 for gender, and 0.360 for BMI. Conclusion: It can be concluded that there is a significant relationship between pulmonary function and gender and there is no significant relationship between pulmonary function with the diagnosis and BMI.
Progression Free Survival pada Pasien Kanker Paru Adenokarsinoma Wild Type dengan Kombinasi Regimen Pemetrexed dengan Cisplatin dibandingkan dengan Karboplatin Agus Setyawan, Ungky; Purnamawati, Catur; Pratiwi, Suryanti
Jurnal Klinik dan Riset Kesehatan Vol 4 No 2 (2025): Edisi Februari
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.2.2

Abstract

Background: Progression-free survival (PFS) is a parameter to measures the progression of wild type adenocarcinoma lung cancer. Literature studies have shown that the combination platinum based-pemetrexed chemotherapy is more effective to prolonged progressivity of wild type adenocarcinoma. Aim: The aim of study to compared the PSF of wild type adenocarcinoma patients receiving cisplatin-pemetrexed and pemetrexed-carboplatin regimens at Dr. Saiful Anwar Hospital in 2018-2021. Methods: A retrospective cohort study based on medical record of wild type adenocarcinoma patients. Results: The results showed that the administration of a carboplatin-pemetrexed regimen has prolonged PFS (median 4 months, 95% CI 2.657-5.343) compared to the cisplatin-pemetrexed regimen (median 2 months, 95% CI 0.988-3.012). In addition, the risk of lung cancer progression based on PFS is not significantly influenced by the Karnofsky scale value of 70-80 (72.2%, HR 0.278). On the other hand, a history of smoking increases the risk of lung cancer progression, although it does not have a significant effect (HR 1,538). Conclusion: Administration of the carboplatin-pemetrexed regimen prolongs PFS up to a range of 10-16 months, although there is no statistically significant difference compared to the cisplatin-pemetrexed.
Co-Authors Delfianto, Dwiroza Delfianto Dini, Zata Dwi Pratiwi, Suryanti Eka Pratiwi Herda Asyari, Claudia Intan Kirana Iqbal Muhammad Listyoko, Aditya Lyono, Albert Mafisah, Saidah Martha , Martha Nur Hikmah, Naila Nur Hikmah Pratiwi, Suryanti Purnamawati, Catur Suardana, I Made Suardana