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INDONESIA
Jurnal Farmanesia
Published by Universitas Sari Mutiara Indonesia
ISSN : """"     EISSN : 25282484     DOI : https://doi.org/10.51544/jf.v8i2
Core Subject : Health,
Medicine & Pharmacology
Jurnal Farmanesia dengan E-ISSN: 2528-2484 merupakan jurnal resmi yang diterbitkan oleh Program Studi S1 Farmasi Fakultas Farmasi dan Ilmu Kesehatan Universitas Sari Mutiara Indonesia, yang artikelnya dapat diakses dan diunduh secara online oleh publik (open access journal). Jurnal ini merupakan jurnal peer-review yang diterbitkan dua kali setahun dengan topik keunggulan hasil penelitian di bidang pelayanan dan praktik kefarmasian, teknologi farmasi, dan disiplin ilmu kesehatan yang berkaitan erat. Jurnal ini menerima teks bahasa Indonesia. Berikut ini adalah area penelitian yang menjadi fokus jurnal ini: 1. Farmakologi 2. Farmasetika 3. Biologi Farmasi 4. Kimia Farmasi 5. Farmakognosi 6. Fitokimia
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 248 Documents
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PEMERIKSAAN Escherichia coli PADA DEPOT AIR MINUM ISI ULANG DIKECAMATAN KOTA KUALA SIMPANG Eka Margaret Sinaga; Erly Sitompul; Elly Sitorus
Jurnal Farmanesia Vol 5 No 2 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (133.731 KB) | DOI: 10.51544/jf.v5i2.2736

Abstract

The availability of clean water is decreasing along with the development of dense population growth. Many households choose Refill Drinking Water as an alternative because the price is relatively cheap. However, no one can guarantee the pathogenic bacteria contained in Refill Drinking Water. This study aims to determine the presence of Escherichia coli bacteria in refill drinking water in Kualasimpang City. This type of research is descriptive with an observational approach. The population in this study were all Refill Drinking Water Depots (DAMIU) in Kualasimpang City in 2018, totaling 21 Refill Drinking Water Depots (DAMIU). The research sample was distributed gallon water, this sample was taken from 5 Refill Drinking Depots which were selected using the Random Sampling method. The results of the study did not show the presence of Escherichia coli bacteria in refilled drinking water but only Coliform pathogenic bacteria. The quality of the water means that it is in accordance with the standards of the Minister of Health of the Republic of Indonesia No.492/MENKES/PER/IV/2010 concerning the requirements for the quality of drinking water, where drinking water must not contain bacteria in it.
PEMERIKSAAN ZAT WARNA MERAH PADA MINUMAN BOTOL YANG BEREDAR DI SEKITAR JALAN KAPTEN MUSLIM MEDAN SECARA KROMATOGRAFI KERTAS Yosy Cinthya Eriwaty Silalahi; Dicky Yuswardi Wiratma; Artha Yuliana Sianipar
Jurnal Farmanesia Vol 5 No 2 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (327.023 KB) | DOI: 10.51544/jf.v5i2.2737

Abstract

Drinks are materials that are needed by living things, which are useful for survival. Therefore, many manufacturers are innovating with drinks, one of which is bottled drinks and adding colorants to drinks to attract buyers. The purpose of this study was to determine whether or not the use of red dye is not allowed in bottled drinks sold around Jalan Captain Muslim Medan. This study uses a descriptive method, namely by conducting examinations in the laboratory. Drinks that are red were taken as samples, namely as many as 5 samples. Samples were purified using wool absorption, followed by identification using paper chromatography compared with tables. The results of the observations showed that from the 5 samples tested, none of the bottled drinks containing red dye were prohibited.
FORMULASI SEDIAAN ANTISEPTIK DARI BUAH RIMBANG (Solanum torvum) SEBAGAI HAND SANITIZER Siti Maimunah; Yettrie Simarmata; Eka Margaret Sinaga; Kristini Siboro
Jurnal Farmanesia Vol 5 No 2 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (226.886 KB) | DOI: 10.51544/jf.v5i2.2738

Abstract

Rimbang fruit (Solanum torvum) has properties as a skin antiseptic. Rimbang fruit extract (Solanum torvum) which has been isolated has antibacterial activity against Staphylococcus aureus bacteria. This is because the Rimbang fruit extract (Solanum torvum) contains compounds such as solasonins, glucosides, saponins, and sterolins. Formulation and testing of antibacterial activity of hand sanitizer gel preparations of Rimbang fruit extract and evaluation of the physical quality of hand sanitizer preparations. Rimbang fruit extract was made by the maceration method using 70% ethanol. Then it was evaporated using a rotary evaporator and the remaining solvent was evaporated until a thick extract was formed. Testing of antibacterial activity by agar diffusion method using disc paper against Staphylococcus aureus by measuring the diameter of the zone of inhibition of bacterial growth. The concentration of Rimbang fruit extract and hand sanitizer gel formula used (F1) 0.5% and (F2) 1%; Evaluation of the physical quality of the hand sanitizer preparation includes organoleptic test, homogeneity test, and pH test. The results of the antibacterial activity test of Rimbang fruit extract against Staphylococcus aureus at a concentration of 0.5% with an inhibitory diameter of 5.2 mm. Meanwhile, the results of the gel hand sanitizer activity test of Rimbang fruit extract obtained the inhibition of Staphylococcus aureus bacteria at a concentration of 1% with a diameter of 9.0 mm.
FORMULASI KRIM ANTI-AGING DARI EKSTRAK KULIT BUAH JERUK LEMON (Citruslimon) Yosy Cinthya Eriwaty Silalahi; Zuhairiah Zuhairiah; Eka Margaret Sinaga; Isra Kristina Sitohang
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (482.568 KB)

Abstract

Anti-aging is a preparation that is useful for preventing or slowing down the effects of aging such as wrinkles, dark spots, rough skin, and enlarged pores. Lemon peel contains flavonoids, namely hesperidin which can prevent aging and can improve skin health. This study aims to formulate anti-aging cream preparations, test the anti-aging effect, and determine the best concentration of anti-aging cream from lemon peel extract. The concentration of lemon peel extract used as a cream ingredient are: 2.5%, 5%, 7.5%, 10%. The tests carried out were homogeneity test, determination of emulsion type, pH, stability observation, skin irritation test. The test was carried out for 4 weeks. The results showed that the anti-aging cream preparations produced were homogeneous and showed an o/w type. The pH test when the cream was made was: 6-7 and after 12 weeks of storage, it was: 5-7. Anti-aging cream preparations have shown a significant increase in skin effects after 1 week, 2 weeks, 3 weeks, and 4 weeks. F5 (10% cream) provides the best anti-aging effectiveness. Lemon peel extract can be formulated into an o/a cream preparation that is able to provide anti-aging effects on the skin. Formula 5 (F5) with a concentration of 10% lemon peel extract was the most.
PENGGUNAAN PATI KENTANG (Solanum tuberosum) LOKAL PREGELATINASI SEBAGAI BAHAN PENGEMBANG PADA TABLET PARASETAMOL GRANUL SECARA KEMPA LANGSUNG Agusmal Dalimunthe; Cut Masyithah Thaib; Yosy Cinthya Eriwaty Silalahi; Mira Eka Diana Br Tarigan
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (684.501 KB)

Abstract

Potatoes have a high nutritional content such as carbohydrates, starch, fat, protein, and water. Almost 90% of medicinal raw materials, both active substances and additives are obtained through imports and abroad, even though Indonesia's natural resources can be developed. This study aims to determine the effect of using pregelatinized local potato starch (Solanum tuberosum) as a developer in paracetamol tablets by direct compression. This research was conducted experimentally using five formulas with certain concentrations of F1 (4%), F2 (6%), F3 (8%), and F4 (10%). Then the tablet evaluation test was carried out, namely the weight uniformity test, tablet hardness test, tablet friability test, tablet disintegration time test. The results showed that the paracetamol tablets with local pregelatinized potato starch developer were made to meet the requirements for weight uniformity test, tablet hardness test, tablet friability test, and tablet disintegration time test. It can be concluded that local pregelatinized potato starch (Solanum tuberosum) can be used as a developer in paracetamol tablets.
PENETAPAN KADAR FLAVONOID TOTAL EKSTRAK ETANOL DAN EKSTRAK ETIL ASETAT DAUN JELATANG (Urticadioica L.) SECARA SPEKTROFOTOMETRI-VISIBLE Ahmad Gazali Sofwan; Yosy Cinthya Eriwaty Silalahi; Siti Nurbaya; Julianto Irawan
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (365.927 KB)

Abstract

Nettle (Urticadioica L.) is a dicotyledonous plant in the Urticaceae family. The nettle plant contains flavonoids. The parts of the nettle plant used as medicine are leaves, roots, and seed stotreatvene real diseases, kidney disorders, allergies, diabetes, anemia, and digestivetract diseases. Nettle leaves contain a lot of secondary metabolites which are active compounds. The purposeofthis study was to determine the appropriate solvent used to obtain nettle leaf extract (Urticadioica L.) withthehighest flavonoid contentfro methanol extract and ethylacetate extract. Determination of total flavonoid contentfrome than olextract and ethylacetate extract of nettle leafe quivalent to quercetin (Quercetin Equivalent (QE)) using aluminum chloridereagentat a wave lengthof 437 nm by Visible spectrophotometry. Base don there search conducted and determined by visible spectrophotometry, the total flavonoid content of nettle leafe than olextract using aluminum chloridereagent was 322.2494 ± 49.2828 mg QE/g extract, whilethe total flavonoid content of nettle leafe thylacetate extract using aluminum chloridereagent was 254,3651 ± 15,0245 mg QE/g extract, The right solventused to obtain nettle leaf extract (Urticadioica L.) with the highest flavonoid contentis ethanol solvent.
PENETAPAN KADAR PROTEIN DALAM SUSU FORMULA BAYI DAN ASI DI MEDAN SECARA KJELDAHL Eka Margaret Sinaga; Siti Maimunah; Erly Sitompul
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (574.669 KB) | DOI: 10.51544/jf.v6i1.2743

Abstract

Breast milk (ASI) is the best food for babies. Breast milk has advantages compared to other milk, including guaranteed cleanliness, the composition of breast milk is also very suitable for digestion, growth, and development of babies, one of the compositions contained in breast milk is protein. Currently, many mothers cannot breastfeed their own babies, so they choose infant formula as a substitute for breast milk. The purpose of this study was to determine differences in protein levels in infant formula and breast milk. Determination of protein content was carried out using the Kjeldahl method which is a simple method for determining total nitrogen in protein and other nitrogen-containing compounds. The Kjeldahl method is carried out through 3 processes, namely: the destruction process, the distillation process, and the titration process according to the procedures and tools used in the Chemistry Laboratory of the Sari Mutiara Indonesia University. The results of the determination of protein levels using the Kjeldahl method contained a protein with average levels in infant formula brand A (10.10 ± 0.96) %, infant formula brand B (10.95 ± 2.43) %, infant formula brand C (11.0666 ± 1.6932) %, and breast milk (20.5733 ± 3.1828) %.
PENERAPAN METODE SPEKTROFOTOMETRI SERAPAN ATOM (SSA) DALAM MENGANALISIS LOGAM MERKURI (Hg) PADA KRIM PEMUTIH WAJAH Siti Nurbaya; Ahmad Gazali Safwan; Maringan Silitonga; Alan Maulana
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (175.128 KB) | DOI: 10.51544/jf.v6i1.2744

Abstract

Whitening cream is a mixture of chemicals and or other ingredients with properties that can fade dark spots on the skin. Whitening cream must be safe and must not contain harmful ingredients such as heavy metal mercury because its toxicity to the organs of the kidneys, nerves, and brain is very strong, so its use is prohibited in cosmetic preparations. The purpose of this study was to determine the levels of metallic mercury (Hg) contained in the preparation of facial whitening creams circulating in Sei Sikambing Market, Medan. The sample used in this study was a facial whitening cream that was not registered with BPOM. The method used to determine mercury levels is qualitatively using color reagents and quantitatively using AAS (Atomic Absorption Spectrophotometry). The results obtained were from 2 samples of facial whitening cream that were used positively for heavy metal mercury (Hg) characterized by the formation of a red-orange precipitate with KI reagent, yellow precipitate by NaOH reagent, white precipitate by HCl reagent. The results of the analysis showed that the highest Hg metal content in the sample with code E was 5.0241 ± 0.4064 g/g. The conclusion of this study is that two samples were positive for mercury, where the use of mercury has been prohibited by BPOM.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN SAMBUNG NYAWA (Gynura procumbens (Lour.)Merr.) TERHADAP BAKTERI Bacillus cereus ATCC 6633 Cut Masyithah Thaib; Zuhairiah Zuhairiah; Artha Yuliana Sianipar; Eta M. Br Simanullang
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (390.441 KB) | DOI: 10.51544/jf.v6i1.2745

Abstract

Life-sustaining plants are plants that are widely used by people as natural medicines. Infectious disease is one of the problems in the health sector. Infection can be caused by various microorganisms, one of which is bacteria. This research was conducted at the Microbiology Laboratory, Sari Mutiara University, Indonesia. This study was conducted to examine the antibacterial activity of the ethanolic extract of life-sustaining leaves using the paper disc diffusion method with concentration variants of 20%, 30%, 40%, 50%, and 60% and used a negative control of DMSO and positive control of chloramphenicol. From the research that has been done, the extract of the continued life leaves has antibacterial inhibitory power. At a concentration of 20% (10 mm). At a concentration of 30% (11 mm). At a concentration of 40% (12.67 mm). At a concentration of 50% (13.3 mm). At a concentration of 60% (15.3 mm). It can be concluded that the ethanolic extract of the grafted life leaves has the highest antibacterial inhibition at a concentration of 60%, which is 15.3 mm.
PENETAPAN KADAR NITRAT PADA IKAN KALENG SARDEN SECARA SPEKTROFOTOMETRI VISIBLE Yettrie Simarmata; Siti Nurbaya; Nina Paramita; Vivi Purwandari
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (571.632 KB) | DOI: 10.51544/jf.v6i1.2747

Abstract

Canned fish is a food that is synonymous with preservatives and food coloring. In the manufacturing process, manufacturers often use natural preservatives to lower production costs. This research is descriptive research. The research location is at PT. Mutifa. Aims to determine how much nitrate levels in branded canned sardines are sold at supermarkets in the city of Stabat whether they meet the requirements of SNI or not. From the results of the study, the levels of nitrate with Brand A were 0.00694% and sardines with Brand B were 0.0453% with a maximum wavelength of 435 nm. According to regulations set by the government according to SNI Number 01-35481994 nitrate levels should not be more than 0.2%. From all samples of canned sardines studied, it was found that nitrate levels were low and did not exceed SNI requirements.

Page 6 of 25 | Total Record : 248

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