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Zahratul Aini
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INDONESIA
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia
Published by Universitas Islam Indonesia
ISSN : 20854145     EISSN : 25272950     DOI : 10.208885/JKKI.Vol10.Iss3.art5
Core Subject : Health,
Medicine & Pharmacology Public Health
JKKI: Jurnal Kedokteran dan Kesehatan Indonesia is a peer-reviewed journal in the field of medical and health sciences. This journal is designed as a place of dissemination of information and scientific knowledge, which publishes three times a year. It publishes original article, article review, and case report. These comprise of biomedical sciences, clinical medicine, public health sciences, and medical science education.
Arjuna Subject : Kedokteran - Kedokteran Keluarga
Articles 11 Documents
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Search results for , issue "JKKI, Vol 9, No 2, (2018)" : 11 Documents clear
Correlation between nurse knowledge and attitude with hand hygiene compliance Azhar Alwi Zakaria; Liena Sofiana
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 2, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss2.art3

Abstract

Background: World Health Organization (WHO) stated that nosocomial infection cause 1,4 million death every day in the world in 2010. Indonesia has a high incidence of infection nosocomial within ten public hospitals in 2010,  where the rate was between 6-16% with an average 9,8%. Nurses are expected to have the knowledge and attitude in the implementation of hand hygiene because education and behavior are the factors involved in performing hand hygiene.Objective: The purpose of this research is to determine the relationship between nurses’ knowledge and attitudes with hand hygiene compliance in Nur Hidayah Hospital, Bantul.Method: This research was an analytic observational study with the cross-sectional design. The variable of this research is knowledge, attitude, and hand hygiene compliance of nurses, with the 40 respondents. This research used questionnaire and checklist sheet. Analysis of data was done using analysis univariate and bivariate (Chi-square) test.Result: The research indicated there was a connection between knowledge and hand hygiene (P= 0,002; 95% CI) and  also there is a connection between attitude and compliance of hand hygiene (P= 0,003;95% CI) at Nur Hidayah Bantul hospital. Those show that attitude is a risk factor. Conclusion: There are connection between nurses’ knowledge and attitude with hand hygiene compliance at Nur Hidayah Bantul hospital.
The effect of co-chemotherapy of ethyl acetate fraction of Long jack roots (Eurycoma longifolia jack) on interleukin-6 expression of 7,12- dimethylbenz anthrasen breast carcinoma model Siti Salma Yusuf; Laela Hayu Nurani; Sitarina Widyarini
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 2, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss2.art7

Abstract

Background: Carcinogenic compound can cause cancer, one of which is 7,12- Dimethylbenz anthrasen (DMBA). Therapy used is chemotherapy using doxorubicin. However, doxorubicin can cause side effects and not specific enough, so it can also impair normal cells and cause resistance, so Long jack roots are needed as co- chemotherapy agent.Objective: To assess the effect of giving co-chemotherapy ethyl acetate fraction of Long jack roots and doxorubicin on the development of breast cancer through inhibition interleukin-6 expression.Methods: A total of 35 female rats SD strain were divided into 5 intervention group, each group contained 7 rats, namely Group 1 (baseline given feed and water), Group 2 (DMBA 20 mg / kg given 2x a week for 5 weeks), Group 3 (DMBA 20mg / kg + Long jack roots Ethyl acetate fraction 100 mg / kg), Group 4 (DMBA 20 mg / kg + Doxorubicin 1,17mg / kg), Group 5 (DMBA 20 mg / kg + Long jack roots ethyl acetate fraction 100 mg / kg + Doxorubicin 1,17mg / kg), then on the 16th week, surgery was done to remove animal’s mammae and organs and to conduct immunohistochemistry test with anti interleukin-6. Results: Interleukin-6 expression test result% with the average value of group I, II, III, IV and V respectively, 6.56 ± 3.50%; 47.21 ± 9.48%; 20.83 ± 10.40%; 49.39 ± 9.87% and 58.37 ± 17.32%.Conclusion: The administration of co-chemotherapy ethyl acetate fraction of longjack roots (Eurycoma longifolia Jack) and doxorubicin is effective inlowering aromatase expression, however not effective in reducing IL-6 expression compared to single regiment doxorubicin in DMBA-induced rat models.
Maternity references on the maternal mortality: decision-making pattern perpective Nur Fadjri Nilakesuma; Rizanda Machmud
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 2, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss2.art5

Abstract

Background: The Research is motivated by the high rate of maternal mortality in the city of Padang. One reason is the delay in the decision making of referral. The pattern of referrral by a midwife decision making is a complicated process that starts with the process of problem identification, problem-solving alternative search, and evaluation of these alternatives.Objective: The purpose of this study is to identify background reference maternity in cases of maternal mortality regarding decision making patterns of midwives in the city of Padang. Methods: This study was a qualitative study using phenomenology. Data collection was done in the work area of Andalas, Kuranji, Pauh, and Nanggalo from May-August 2016. The selection of informants used snowball sampling technique. Qualitative data were collected through in – depth interviews, and secondary data were collected through document review. Analyzed using a fixed comparison method according to Glaser and Strauss.Results: The result of the study shows that the identification of risk factors performed during antenatal care makes midwives decide to refer to hospitals. However, the referral was rejected by the hospital because there was no emergency alert to the mother. When an emergency occurs during labor, the midwife immediately refers to the patient but tends to be in an unstable patient state. Sothe midwife is blamed for not indicating on time. The decision patterns of midwives in referring maternal mothers to maternal mortality cases are influenced by screening of emergency risk factors, the principle of referral and post-referral impacts.Conclusion: Limitations of authority, identification of risk factors, and post-referral impacts make the midwife utterly wrong in making a referral decision.
Corpus alienum in rectosigmoid: a Case report Agung Widianto; Wahyu Kartiko Tomo; Fuad Dheni Musthofa; Ghana Hendra
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 2, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss2.art11

Abstract

A 48-year old man, a referred patient from Wonosobo Hospital, presented to our hospital with severe lower abdomen to anal discomfort since seven days before admission. It is a sudden pain without apparent causes or triggers and accompanied by blood. The patient is uncooperative when asked about the history of inserting objects into the anus and his sexual behaviour. On plain x-rays, a picture of a tubular object in the rectosigmoid region was discovered. After the operation, a foreign body in the form of a Polyvinyl Chloride (PVC) pipe was extracted.
Preliminary study of a-mangosteen nanoparticles in the sunscreen cosmeceutical product Hanny Setyowati; Wahyuning Setyani
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 2, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss2.art10

Abstract

The growing interest in the cosmeceuticals by natural products has fostered research on the screening of plant-derived raw materials for identifying new antioxidants. Fruit peels as sources of powerful natural antioxidants are often the waste parts of various fruits from daily consumption or food industry. Among the fruit peels, mangosteen peel is an essential source of natural phenolic antioxidants. The a-mangosteen, known as the first compound of Garcinia mangostana L, has the most potent antioxidant activity among the other substances. The new application into sunscreen product will be potentially based on their activity to inhibit the photo-damaged caused by free radical elements from ultraviolet A and B (UVA and UVB). Thus, this formulation into a nanoparticle product may achieve a better effect and efficacy both as cosmetics and pharmaceutics.
Correlation of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, lymphocyte-to-monocyte ratio and carcinoembrionic antigen level in colorectal cancer Oktania Candrawati; Bambang Eko Broto Hari Utomo; lmam Sofii
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 2, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss2.art4

Abstract

Background: Colorectal cancer is one of cancer that has a high mortality rate. Cancer is associated with a systemic inflammatory response. Carcinoembryonic antigen (CEA) is a colorectal cancer prognostic marker, but this examination is quite expensive and not always ubiquitously available. Therefore, systemic inflammatory markers through routine blood examination are expected as a colorectal cancer marker. Objective: The present study is to determine a correlation of neutrophil-lymphocyte ratio (NLR), the platelet-lymphocyte ratio (PLR), the lymphocyte-monocyte ratio (LMR) and CEA level in colorectal cancer patients. Methods: This retrospective cross-sectional study was conducted in November 2016-January 2017 at Dr. Sardjito Hospital, Yogyakarta. As many as 209 patients who underwent surgery in January 2015-Decemberr 2016 with colorectal cancer histopathologic diagnosis were included. Demographic, clinical, histopathology and preoperative NLR, PLR, LMR and CEA level was obtained from medical records. Correlation of NLR, PLR, LMR and CEA level was analyzed with Somer’s test. Result: As many as 51.2% of subjects were male. Most subjects (n 42.6%) were diagnosed at 45-60 years old. The most common location of the tumor is in rectum (65.1%). Histopathology examination showed well differentiation in 51.7% subjects. The Somer’s analysis showed there was correlation of NLR and CEA level (p=0.023, r=0.164), there was a correlation between PLR and CEA level (p=0.016, r=0.146). Higher NLR and PLR was proportional to higher CEA level. There was a correlation of LMR and CEA level (p=0.001, r=-0.188), lower LMR correlates to higher CEA level.Conclusion: There is significant positive correlation of NLR and CEA level, PLR and CEA level, and negative correlation of LMR and CEA level in colorectal cancer patients.
Retention of basic life support in medical students of Airlangga University Inna Maya Sufiyah; Bambang Pujo Semedi; Sundari Indah Wiyasihati
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 2, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss2.art9

Abstract

Background: Cardiac arrest is one of the leading cause of death in the world with steadily increasing number over the years. Basic life support has been proven to lower the risks of tissue damage and further complication. Several study shows that BLS skill are lacking in some doctors and nurses.Objective: Therefore, the purpose of this study is knowing the retention of basic life support in medical student of Airlangga University.Methods: This descriptive study used cross sectional design. Subjects were students at faculty of medicine in Airlangga University who trained one year ago and completed their study of Basic Life Support. Fifty two subject were asked to practice their BLS techniques then scored based on modified American Hearth Assosiation (AHA)’s Basic life support skill checklist.Results: Based on the data, the percentage of students who did the retest correctly: response checked by shouting 92.31% students, response checked by tapping 69.23% students, call for help 44.23% students, airway checked 48.08% students, breathing checked 46.15% students, correct hand placement 100% students, compression rate 78.85% students, compression ratio 75% students, position 94.23% students, and compression depth 78.85% students. Conclusion: One year post training and test, 14 from 52 students could complete all the steps in basic life support skill. Less than a half of the students successfully done 3 out of 10 points that were being tested. Meanwhile, many aspects in circulation point show higher results all above 75%.
The effect of the onset of seizure on clock drawing test score of epilepsy patients Baiq Kania Kartika Yaksa; Herpan Syafii Harahap; Emmy Amalia; Yanna Indrayana
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 2, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss2.art6

Abstract

Background: Epilepsy is one of the causing factors of cognitive impairment which affects the patient’s quality of life. The most critical risk factor for cognitive impairment in epilepsy patients is the onset of seizure. Performing detection of cognitive impairment in those patients is crucial. Clock Drawing Test (CDT) is a validated instrument for the detection of cognitive impairment in epilepsy patients.Objective: This study was aimed to investigate the effect of the onset of seizure on CDT score in epilepsy patients.Methods: This study was a cross-sectional study involving 64 epilepsy patients of Mutiara Sukma Mental Hospital, West Nusa Tenggara, who met the inclusion but not exclusion criteria. The clinical and demographic characteristics data collected in this study were age, gender, type of seizure, etiology, length of education, duration of treatment, and antiepileptic drugs (AED). Cognitive function evaluation has been done by using the CDT instrument. Analysis of the effect of the beginning of seizure on CDT score was carried out by observing the influence of the clinical and demographic characteristics data.Results: There was a significant difference between the onset of seizure on CDT score (p<0.05). There were significant differences in aetiology and age in both groups of onsets of the seizure (p <0.05), but not in the characteristics of gender, type of seizure, level of education, duration of treatment and AED in both groups of onsets of the seizure (p>0.05).Conclusion: The onset of the seizure in epilepsy patients affect CDT score. This effect might be attributed to etiology and age of epilepsy patients.
Relationship between breastfeeding and the incidence of diarrhoea in children aged 6-24 months Manmeet Kaur Gurbachan Singh; Mahrani Lubis
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 2, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss2.art8

Abstract

Background: Diarrhoea is still a global problem with high mortality. Children who are malnourished or have impaired immunity have the highest risk of diarrhoea. Exclusive breastfeeding in infants is known could protect the babies against diarrhoea.Objective: This study aims to determine the relationship between exclusive breastfeeding with the incidence of diarrhoea in children aged 6-24 months.Methods: This is an observational study where the data collected during August-November 2017 at Padang Bulan Primary Health Care. The subjects are a mother who has children between 6-24 months. The primary data was obtained through interviews using a validated structured questionnaire. The relationship between exclusive breastfeeding and the incidence of diarrhoea were analysed using Chi-square. Statistical analysis was performed in 95% coefficient interval (alpha=0,05).Results: Amongst 98 children, 53.1% are female. Children who have received exclusive breastfeeding were 53 children (54.1%). The number of children who had diarrhoea was 68.4% while many diarrhoea frequencies were 49%. Only 29 children (29.6%) had diarrhoea with exclusively breastfeeding, while 38 children (38.8%) had diarrhoea without exclusive breastfeeding. There is a relationship between exclusive breastfeeding to the incidence of diarrhoea in children aged 6-24 months (p= 0,002).Conclusion: There is a significant relationship between exclusive breastfeeding and the incidence of diarrhoea in children aged 6-24 months.
Commercializing oocytes in the era of therapeutic cloning; an extension of pro-life vs pro-choice debates Teguh Haryo Sasongko
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 2, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss2.art2

Abstract

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