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All Journal Majalah Kedokteran Bandung Folia Medica Indonesiana JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Majalah Biomorfologi (Biomorphology Journal) Jurnal Layanan Masyarakat (Journal of Public Service) Cardiovascular and Cardiometabolic Journal (CCJ) Essential: Essence of Scientific Medical Journal JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Warta LPM
Sundari Indah Wiyasihati
Department Of Physiology And Biochemistry, Faculty Of Medicine, Universitas Airlangga.
Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Potensi Bayam Merah (Amaranthus tricolor L) sebagai Antioksidan pada Toksisitas Timbal yang Diinduksi pada Mencit Wiyasihati, Sundari Indah; Wigati, Kristanti Wanito
Majalah Kedokteran Bandung Vol 48, No 2 (2016)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (657.338 KB) | DOI: 10.15395/mkb.v48n2.758

Abstract

Seiring dengan peningkatan industrialisasi dan transportasi, polusi logam berat yang ditimbulkan pun semakin meningkat. Timbal merupakan toksin yang paling bermakna di antara logam berat lain yang memiliki kecenderungan untuk mengkatalisis reaksi oksidasi dan menimbulkan terbentuknya Reactive Oxygen Species (ROS). Bayam merah (Amaranthus tricolor L) mengandung komponen antioksidan yang berpotensi menurunkan kadar timbal dalam darah dan mencegah toksisitasnya. Penelitian dilaksanakan di Laboratorium Biokimia Fakultas Kedokteran Universitas Airlangga selama bulan Agustus–September 2012. Penelitian eksperimental laboratoris ini menggunakan posttest only control group design. Tiga puluh ekor mencit dibagi menjadi tiga kelompok: K0 sebagai kelompok kontrol yang diberikan akuades dan plasebo, K1 sebagai kelompok perlakuan yang diberikan timbal asetat 0,75 mg/10 gBB dan plasebo, K2 sebagai kelompok perlakuan yang diberikan timbal asetat 0,75 mg/10 gBB dan 382,2 mg/10 gBB jus bayam merah selama 28 hari. Darah diambil dari vena ekor tikus untuk pemeriksaan superoxide dismutase (SOD) dan malondialdehyde (MDA). Hasil pemeriksaan kadar SOD rata-rata darah mencit pada K0 (n=10) 55,91 ± 9,61%, K1 (n=10) 31,29 ± 12,87%, dan K2 (n=10) 34,83 ± 10,12% (p=0,000). Nilai kadar MDA rata-rata darah mencit pada K0 9,9 nmol/mL, K1 12,04 nmol/mL, dan K2 11,05 nmol/mL (p=0,002). Berdasarkan uji ANOVA, disimpulkan bahwa bayam merah dapat meningkatkan SOD dan menurunkan MDA plasma pada toksisitas yang diinduksi timbal asetat pada mencit. [MKB. 2016;48(2):63–7]Kata kunci: Amaranthus tricolor linn, antioksidan, bayam merah, toksisitas timbal The Potency of Red Spinach (Amaranthus tricolor L) as an Antioxidant for Lead-Induced Toxicities in MiceAbstractAlong with the increasing industrialization and transportation, the generated heavy metal pollution is increasing. Lead is the most significant toxin among heavy metals and has a tendency to catalyze the oxidation reaction and lead to the formation of Reactive Oxygen Species (ROS). Red spinach (Amaranthus tricolor L) contains antioxidant properties which have a potential to reduce the blood lead level and prevent the lead-induced toxicities. The study was conducted at the Laboratory of Biochemistry Faculty of Medicine, Universitas Airlangga, during August–September 2012. This laboratory experimental study used pos-ttest only control group design. Thirty mice were divided into 3 groups: K0 as the control group with aquadest and placebo; K1 as the treatment group with lead acetate 0.75 mg/10 gBW and placebo treatment; and K2 as the treatment group with  lead acetate 0.75 mg/10 gBW and 382.2 mg/10 gBW red spinach juice treatment for 28 days. Blood was drawn from the mouse’s tail vein for examination of superoxide dismutase (SOD) and malondialdehyde (MDA). Mean blood SOD value in K0 (n=10) was 55.91 ± 9.61%, K1 (n=10) was 31.29 ± 12.87%, and K2 (n=10) was 34.83 ± 10.12% (p=0.000). Mean blood MDA value for K0 was 9.9 nmol/mL, K1 was 12.04 nmol/mL, and K2 was 11.05 nmol/mL (p=0.002). Based on ANOVA test, it is concluded that the administration of red spinach can increase SOD and decrease MDA plasma on lead-induced toxicity in mice. [MKB. 2016;48(2):63–7]Key words: Amaranthus tricolor linn, antioxidant, lead-induced toxicities, red spinach
Prevalensi dan Luaran Gangguan Hemodinamik Dengue Shock Syndroma pada Anak Di Departemen Anak RSUD Dr SOetomo Fenska Seipalla; Ira Dharmawati; Sundari Indah Wiyasihati
Essence of Scientific Medical Journal Vol 18 No 1 (2020): Volume 18 No. 1 (Januari - Juni 2020) Essential: Essence of Scientific Medical J
Publisher : Kelompok Ilmiah Hippocrates Fakultas Kedokteran Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/ESTL.2020.v18.i01.p06

Abstract

Abstract The prevalence of Dengue infection has increased markedly worldwide. Dengue shock syndrome (DSS) is a severe manifestation of dengue virus infection. Higher mortality of DSS was found in children. This study’s aim was to portray prevalence and hemodynamic outcome in children attending the department of pediatric in Dr. Soetomo General Hospital. A Descriptive Retrospective study of children aged <15 years old with DSS was performed and evaluated from 2013-2016. The samples were divided into 5 groups, aged <1 years old, 1-2 years old, 3-5 years old 6-11 years old and 12-15 years old. Data were taken secondarily and calculated with Microsoft Excel 2010. The most common findings were prevalence of DSS in 6-11 years old group and mortality rate in <1 years old group. This can be seen as in the hemodynamic outcome; the average HR was higher in aged group 1-2 years old while RR was higher in group under 1-year-old. Meanwhile, the average blood pressure, PP, and MAP were lower in children under 2 years old. The hemodynamic outcome varies on each group based on age. Incidence of DSS remained high in older children but mortality rates were high in younger children.
Retention of basic life support in medical students of Airlangga University Inna Maya Sufiyah; Bambang Pujo Semedi; Sundari Indah Wiyasihati
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 9, No 2, (2018)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol9.Iss2.art9

Abstract

Background: Cardiac arrest is one of the leading cause of death in the world with steadily increasing number over the years. Basic life support has been proven to lower the risks of tissue damage and further complication. Several study shows that BLS skill are lacking in some doctors and nurses.Objective: Therefore, the purpose of this study is knowing the retention of basic life support in medical student of Airlangga University.Methods: This descriptive study used cross sectional design. Subjects were students at faculty of medicine in Airlangga University who trained one year ago and completed their study of Basic Life Support. Fifty two subject were asked to practice their BLS techniques then scored based on modified American Hearth Assosiation (AHA)’s Basic life support skill checklist.Results: Based on the data, the percentage of students who did the retest correctly: response checked by shouting 92.31% students, response checked by tapping 69.23% students, call for help 44.23% students, airway checked 48.08% students, breathing checked 46.15% students, correct hand placement 100% students, compression rate 78.85% students, compression ratio 75% students, position 94.23% students, and compression depth 78.85% students. Conclusion: One year post training and test, 14 from 52 students could complete all the steps in basic life support skill. Less than a half of the students successfully done 3 out of 10 points that were being tested. Meanwhile, many aspects in circulation point show higher results all above 75%.
BODY MASS INDEX WITH SYSTOLIC AND DIASTOLIC BLOOD PRESSURE AT A PUBLIC HEALTH CENTER IN SURABAYA, INDONESIA Bella Patricia Simanjorang; Florentina Sustini; Sundari Indah Wiyasihati
Majalah Biomorfologi Vol. 33 No. 1 (2023): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v33i1.2023.14-19

Abstract

Highlights1. The Body Mass Index (BMI) measures how much fat the body carries.2. Obesity and overweight are characterized by an excessive buildup of fat that may be detrimental to health. AbstractBackground: Body Mass Index (BMI) is an indicator of body fat. It is classified as underweight, normal, overweight, and obese. Obesity is a risk factor for hypertension (systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg). Objective: To analyze the correlation between BMI with systolic and diastolic blood pressure. Methods: This was an observational research with a cross-sectional design, and the samples consisted of 60 individuals aged 35 to 59 selected using accidental sampling. Blood pressure was the dependent variable whereas BMI was the independent variable. Data were analyzed using Pearson and Spearman correlation tests. Results: There were 44 females (73.3%) and 16 males (26.7%). The largest age groupings were between 45-49 and 50-54 years (31.7%), while the smallest was between 55-59 years (5%). Thirty-three samples (55%) were overweight (>25 kg/m2), 32 samples (53.4%) had systolic blood pressure above normal (≥120 mmHg), and 42 samples (70%) had diastolic blood pressure above normal (≥80 mmHg). The Pearson correlation test between BMI and systolic blood pressure showed a weak correlation (p=0.009 r=0.336). The Spearman correlation test between BMI and diastolic blood pressure showed a weak correlation (p=0.013 r=0.321). Conclusion: There was a weak correlation between BMI with systolic blood pressure, and there was a weak correlation between BMI with diastolic blood pressure in this study.
“LET’S MOVE!” CAMPAIGN: EDUCATION AND STIMULATION OF PHYSICAL EXERCISE IN OLDER ADULTS Sundari Indah Wiyasihati; Hayuris Kinandita Setiawan; Purwo Sri Rejeki; Irfiansyah Irwadi
Jurnal Layanan Masyarakat Vol. 7 No. 1 (2023): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jlm.v7i1.2023.123-130

Abstract

The increase in human life expectancy has led to an increase in the number of older adults worldwide, including in Indonesia. The aging population raises sarcopenia as a further problem in geriatric medicine. Sarcopenia is a syndrome characterized by progressive skeletal muscle mass and strength loss. This syndrome is associated with reduced quality of life, increased risk of falls, and even death. Physical exercise is the only effective intervention strategy. Therefore, we designed this community service program for socializing the healthy lifestyle of the elderly with one focus on physical exercise as a promotive, preventive, and curative effort on the incidence of sarcopenia in the elderly. The method chosen was socialization and educating fifty-two pre-elderly and elderly target partners regarding the healthy lifestyle for the older adults and elderly exercise activities as stimulation. The "Let's Move!" campaign that has been implemented can socialize and increase the knowledge of target partners regarding sarcopenia and physical exercise as an intervention for prevention and treatment. The formulation of the main guidelines for safe exercise for the elderly can be useful for target partners who generally already have one type of condition that limits their ability to carry out activities of daily living.
Optimalisasi Peran Kader Kesehatan dalam Edukasi dan Implementasi Gaya Hidup Sehat Lansia Sundari Indah Wiyasihati; Hayuris Kinandita Setiawan; Purwo Sri Rejeki; Lilik Herawati
Warta LPM WARTA LPM, Vol. 26, No. 2, April 2023
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (340.432 KB) | DOI: 10.23917/warta.v26i2.1443

Abstract

The health problems of the elderly in ​​the Puskesmas Industri, Gresik work area align with the Indonesian health phenomenon where the number of elderly and degenerative diseases is high. Health cadres training in the work area of ​​the Puskesmas Industri is needed to optimize the role of cadres in educating and implementing a healthy lifestyle in older adults. The Community Partnership Program, focusing on health as part of goal 3 of The Sustainable Development Goals (SDGs), was carried out on September 1, 2022, and was attended by 57 cadres from 6 villages. Health information was provided as a provision for cadres to provide education to the public about the healthy lifestyle of the elderly. The results showed that there was an increase of 17,26 points (34,76%) after training. The lowest post-test results were on the topic of BMI and its interpretation, as well as physical activity in the elderly, so further action is needed. During FGD, the Elderly Health Book from the Ministry of Health of the Republic of Indonesia was introduced. The results of the FGD showed that the introduction of the Elderly Health Book should be continued so that health cadres can consistently use it. Health cadres have a significant role in realizing the elderly health program from the Indonesian Ministry of Health. This health cadre training has proven to be very necessary because it can increase understanding as a provision for cadres in providing education to the public regarding the healthy lifestyle of the elderly.
Reperfusion Time of STEMI Patients in Indonesia and Outside Indonesia Muhammad Fachriyan Romadhona; Yudi Her Oktaviono; Sundari Indah Wiyasihati; Rosi Amrilla Fagi
Cardiovascular and Cardiometabolic Journal (CCJ) Vol. 4 No. 2 (2023): Cardiovascular and Cardiometabolic Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ccj.v4i2.2023.85-98

Abstract

Highlights: 1. The median of door-to-ballon in handling STEMI and total ischemic time is longer in Indonesia than other countries. - Background: STEMI is a medical emergency that requires quick treatment. Several problems might arise from the improper and delayed treatment of STEMI patients. Objective: This study aimed to examine the differences in the reperfusion time of STEMI patients in Indonesia and outside Indonesia. Method: Systematic Review method is used without meta-analysis. The variables to be studied in this study are Door-to-Balloon time and Total Ischemic Time. PubMed, Science Direct, and Scopus are used as search tools using the MeSH terms and keywords that have been determined to look for articles within 2017 – 2020. The selection of the literature that has been obtained was carried out according to the PRISMA algorithm. Results: Twelve journals were used that were relevant, compatible, and following the inclusion and exclusion criteria. It was found that the median door-to-balloon in handling STEMI in Indonesia ranged from 70 to 94 minutes, while the median total ischemic time ranged from 275 to 461 minutes. Meanwhile, the median door-to-balloon time and total ischemic time outside Indonesia ranged from 41 to 87 minutes and 112 to 273 minutes, respectively. Conclusion: In conclusion, the median and average door-to-balloon time and total ischemic time in Indonesia are longer than the door-to-balloon time and total ischemic time outside Indonesia in handling STEMI.
The Relationship between Early Initiation of Breastfeeding and Exclusive Breastfeeding in the Work Area of Wiyung Public Health Center, Surabaya Nisrina, Vira Dwi; Wiyasihati, Sundari Indah; Fatmaningrum, Widati; Sulistiawati, Sulistiawati
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 10 No. 2 (2019): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (253.577 KB) | DOI: 10.20473/juxta.V10I22019.48-51

Abstract

Introduction: In Indonesia, there has been a 10% increase in the span of five years for exclusive breastfeeding, however this is still far from the national target. One of the factors that can cause low rates of national exclusive breastfeeding is that not all babies have received an early initiation of breastfeeding. The purpose of this study was to determine the relationship between early initiation of breastfeeding and exclusive breastfeeding for babies aged 7-12 months in the work area of Wiyung Public Health Center, Surabaya. Methods: This study was a quantitative research with a cross-sectional approach. The study used a questionnaire as the research instrument given to 30 respondents, namely mothers who had 7-12 month old babies in the work area of Wiyung Public Health Center, Surabaya. Results: The percentage of early initiation of breastfeeding in babies aged 7-12 months was 53.33% meanwhile the percentage of exclusive was 73.33%. Using Chi Square Fisher Exact Test, it was found that there is no relationship between early initiation of breastfeeding and exclusive breastfeeding for babies aged 7-12 months in the working area of the Wiyung Public Health Center in Surabaya. (The value of p = 0.574 with a value of α = 0.05, p>α). Conclusion: The early initiation of breastfeeding is not the only factor influencing exclusive breastfeeding for babies aged 7-12 months in the work area of the Wiyung Public Health Center in Surabaya. Further research is needed on other factors that can relate to and influence exclusive breastfeeding.
POTENCY OF CV12 ACUPUNCTURE AS OBESITY PREVENTION THROUGH MODULATION OF  AND  ESTROGEN RECEPTORS EXPRESSION ON THE ADIPOSE TISSUE OF OVARIECTOMIZED MICE Rejeki, Purwo Sri; Wiyasihati, Sundari Indah; Atika, Atika
Folia Medica Indonesiana Vol. 53 No. 1 (2017): JANUARY - MARCH 2017
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (279.58 KB) | DOI: 10.20473/fmi.v53i1.5496

Abstract

This study aims to determine the potency of CV 12 acupuncture as prevention of weight gain in ovariectomizedmice (OVX). Female mice strain BALB/c, 28 mice, 3-4 weeks, 25-35 grams were divided into four groups; namely K1 (n = 8, sham and vehiculum injection), K2 (n = 8, OVX and vehiculum injection), K3 (n = 7, OVX and injection of estrogen intraperitoneal 10 mg/kg/day) and K4 (n = 6, OVX and CV12 acupuncture with a frequency of 2 Hz in 10 mA of continuous spike current wave).Injection and acupuncture given every day for four weeks. Weight change in K1 (0.75 ± 2.8) grams, K2 (2.71 ± 2.4) grams, K3 (0.71 ± 0.95) g and K4 (0.93 ± 2.40) gram with a significant difference in the K2 and K4 (p = 0.011). a receptor expression in K1 (12.25 ± 2.96), K2 (5.43 ± 2.64), K3 (18.86 ± 1.57), K4 (17 ± 2.00) with a significant difference to the K2 K1, K3 and K4 with p<0.05. b receptor expression in K1 (11.38 ± 1.92), K2 (4 ± 1.41), K3 (16.86 ± 1.86), K4 (14.17 ± 5.24) with significantly different a receptor expression in visceral fat mass on the group K2 to K1, K3 and K4 with p<0.05. CV 12 acupuncture increases the expression of a and b estrogen receptor in visceral adipose tissue of OVX mice equivalently and able to prevent the increase of weight due to the estrogen withdrawal. This point could potentially be used as one of the management ofobesity prevention in menopause.
INITIATION OF THE FORMATION OF FIT VILLAGE AS AN EFFORT TO PREVENT METABOLIC DISEASES IN SINGOTRUNAN VILLAGE, BANYUWANGI Herawati, Lilik; Argarini, Raden; Irwadi, Irfiansyah; Setiawan, Hayuris Kinandita; Wiyasihati, Sundari Indah; Azmy, Ulul
Jurnal Layanan Masyarakat (Journal of Public Services) Vol. 8 No. 2 (2024): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jlm.v8i2.2024.270-278

Abstract

Metabolic disease is an epidemic phenomenon that affects both men and women from various ages, ethnic, and socio-economic groups. The term metabolic disease itself is an umbrella term that includes, among others: hypertension, type 2 diabetes mellitus, hyperlipidemia, obesity, and non-alcoholic fatty liver disease. Lifestyles such as poor nutrition, physical activity, and habits are risk factors that can increase the incidence of metabolic disease. Therefore, prevention of metabolic diseases is necessary, including for ordinary people. Metabolic disease, namely hypertension, is in 3rd place and diabetes is in 10th place, the most common disease suffered by residents of Singotrunan Village, Banyuwangi. In this regard, it is important to make efforts to prevent metabolic disease and even death due to complications from metabolic disease. This community service program is designed to create a fit village as a sustainable healthy lifestyle, initiated through health checks for screening, exercise training, education and discussions as encouragement to do regular exercise. The participants' pre-test and post-test results showed a significant increase in their level of knowledge (p=0.01). The results of the participant satisfaction test showed that 80.9% of participants said they were very satisfied and the rest (19.1%) said they were satisfied. It is hoped that the PKM activity to initiate a fit village in Singotrunan Village, Banyuwangi will provide motivation for residents to exercise regularly and can become a model village for residents of other areas.
Co-Authors Atika Atika Azmy, Ulul Bella Patricia Simanjorang Deshinta Fitrianti Syahida Dharmawati, Ira Fenska Seipalla Florentina Sustini HERAWATI, LILIK Imam Susilo Inna Maya Sufiyah Irwadi, Irfiansyah Muhammad Fachriyan Romadhona Nisrina, Vira Dwi Raden Argarini Rejeki, Purwo Sri Rosi Amrilla Fagi Semedi, Bambang Pujo Setiawan, Hayuris Kinandita Sulistiawati Sulistiawati Widati Fatmaningrum Wigati, Kristanti Wanito Yudi Her Oktaviono, Yudi Her