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Contact Name
Indra Cahya Setia Widigda
Contact Email
indracahya933@gmail.com
Phone
+6281252438535
Journal Mail Official
kedokterankomunitas@unisma.ac.id
Editorial Address
Jl. M.T. Haryono No.193 Malang 65144, Jawa Timur
Location
Kota malang,
Jawa timur
INDONESIA
Jurnal Kedokteran Komunitas (Journal of Community Medicine)
ISSN : 23376988     EISSN : -     DOI : 10.33474
Jurnal Kedokteran Komunitas merupakan salah satu jenis jurnal akademik bidang kedokteran atau kesehatan di mana penulis mempublikasikan artikel ilmiah hasil penelitian maupun kajian. Artikel ilmiah ini juga mencangkup hasil-hasil penelitian terbaru dan tulisan ilmiah lainnya di bidang biomedis, kedokteran klinis, kedokteran komunitas, dan kesehatan masyarakat. Untuk memastikan kualitas ilmiah pada artikel yang diterbitkan, suatu artikel biasa diteliti oleh rekan-rekan sejawatnya dan direvisi oleh penulis, hal ini dikenal sebagai peer review. Jurnal Kedokteran Komunitas nomor p-ISSN 2337-6988 e-ISSN dikelola Fakultas Kedokteran Universitas Islam Malang ini diharapkan dapat menjadi media berbagi pengalaman antara berbagai kalangan dan institusi pendidikan kedokteran dan kesehatan, dengan terbit berkalah 2 kali dalam setahun yaitu bulan April dan Oktober.
Articles 14 Documents
Search results for , issue "Vol 6, No 3 (2018)" : 14 Documents clear
POTENSI SARI BIJI KEDELAI (Glycine max), RIMPANG JAHE (Zingiber officinale) DAN KOMBINASINYA TERHADAP KADAR SUPEROXIDE DISMUSTASE (SOD) DAN JUMLAH NEKROSIS SEL EPITEL GLOMERULUS GINJAL PADA TIKUS MODEL DIABETES MELLITUS Eragraditya Hardianto
Jurnal Kedokteran Komunitas Vol 6, No 3 (2018)
Publisher : Jurnal Kedokteran Komunitas (Journal of Community Medicine)

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Abstract

Introduction: the complications of nephropathy in diabetics are risk factors for renal failure. Soybean and ginger rhizomes are herbs with antioxidant and antidiabetic that are used as alternative therapies for diabetic nephropathy in diabetes, but the combined form of soy-ginger (delja) has never been studied. This study aims to determine the potential of soybeans and ginger seeds, as well as their combination of SOD levels and the number of necrosis of renal glomerular epithelial cells in diabetes.Methods: This study use 12-week-old Sprague dawley male rats were divided into normal control groups, treatment control groups (positive controls) and 4 treatment groups. The rats were induced on a multi-dose diet of 25 mg/kg of fat-rich body weight (DTLF) and streptozotocin. The rat was administrated orally with soybean extract 5 g/kgBB, ginger rhizome 500 mg/kgBB, combination of delja I and delja II. Measurements of SOD in the kidneys using a microplate reader with a wavelength of 450 nm, while necrosis of the renal glomerular epithelial cells uses the ratio formula in (%).Data analyzed by using the One Way ANOVA analysis continued with Least Significant Difference (LSD) (p <0.05).Results: The extract of ginger rhizome and combination of delja II can increase the levels of SOD by approximately 10% and 20% (p <0.05). The combination of soybean extract, ginger rhizome extract, delja I and a combination of delja II significantly decreased glomerular renal epithelial cell necrosis in rats with DM of 32 %, 33 %, 30 %, and 50 %. Induction of DTLF and STZ in the treatment control group decreased renal SOD levels and increased necrosis of renal glomerular epithelial cells about 20 % and four fold, respectively, relative to the normal control group.Conclusion: The combination of rhizome extract of ginger and delja II increased the levels of SOD in the kidney of rats with DM model. While administering soybean extract, ginger rhizome, combinations of delja I and delja II decreased necrosis of glomerular epithelial cells.
PENGARUH JUMLAH PASIEN RAWAT INAP TERHADAP JUMLAH KOLONI BAKTERI PADA GAGANG PINTU DAN TEMPAT TIDUR PASIEN DI SALAH SATU RUMAH SAKIT DI KOTA MALANG Lillah Savina
Jurnal Kedokteran Komunitas Vol 6, No 3 (2018)
Publisher : Jurnal Kedokteran Komunitas (Journal of Community Medicine)

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Abstract

Introduction: Nosocomial infection is an infection that is obtained by the patient during treatment in a hospital or other health facility that is not found when the patient is hospitalized and arises after 48 hours. The density of a room can affect the number of bacteria that exist, especially on objects that are often touched by patients, medical personnel, or visitors, for example such as patient beds and door handles. This study aims to look at the effect of the number of patients on the number of bacterial colonies on patient beds and door handles.Methods: This research is an in vitro study using observational analytic research design post test only by comparing the type and number of bacteria in the door handles and patient beds in a room with the number of patients. Bacteria are cultured on Nutrient Agar, MacConkey, and Blood Agar media to determine the number and characteristics of bacterial colonies. Data analysis using Mann-Whitney Test. The results are said to be significant if (p <0.05).Result: On nutrient agar media, bacterial colonies were obtained which were suspected to be Bacillus sp. and Staphylococcus sp. Macconkey media obtained colonies of Enterobacteriaceae and Salmonella sp. bacteria. or shigella sp. The blood agar media obtained colonies of Streptococcus sp. bacteria. and Pseudomonas aeruginosa. The number of bacterial colonies on the doors in the classroom I room compared to the doors of class II showed no significant differences (p> 0.05). Comparison of the number of bacterial colonies in beds in class I and class II rooms did not differ significantly (p> 0.05). The number of patients did not correlate with the number of bacterial colonies on the door and bed (p <0.05).Conclusion: There is no effect of the number of patients on increasing the number of bacterial colonies.
Efek Paparan Subkronik Dekokta Daun Nimba (Azadirachta indica) terhadap Hiperplasia Lamela Insang dan Perubahan Kecepatan Berenang Ikan Zebra (Danio rerio) Juvenile Ineke Romadina Evi N
Jurnal Kedokteran Komunitas Vol 6, No 3 (2018)
Publisher : Jurnal Kedokteran Komunitas (Journal of Community Medicine)

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Abstract

Introduction: Neem leaves (Azadirachta indica) has many benefits including antibacterial, antifungal and antimalarial. Toxicity tests need to be carried out to determine the effects and safety of using neem during growth and development. Exposure neem 60 mg / L in the early stages of Cyprinus carpio L life induces focal separation and gill lamellae edema. The aim of this study is to determine the effect of neem leaves subchronic exposure to gill lamellar hyperplasia and swimming speed of D.rerio juvenilee.Method: Juvenilee zebrafish of 1.5 months old were exposed to Neem leaf decoction (DDN). To observe gill lamella hyperplasia, D.rerio juvenilee was exposed for 15 days to DDN dose of 50 mg / L, 132 mg / L, and 410 mg / L. On the 16th day, gill tissue was taken and stained them using Hematoxylin Eosin (HE). Gill lamella cell was counted using binocular microscope with 1000x magnification. To observe swimming speed changes, D.rerio juvenilee was exposed to DDN for 30 minutes and analyzed using tracker software. Data were analyzed using One-way analysis of variance (ANOVA) continued with Least Significant Difference (p <0.05).Results: Subchronic exposure of D.rerio juvenilee to DDN doses 132 mg / L and 410 mg / L increase gill secondary lamella hyperplasia significantly compared to controls (p <0.05) but insignificant in dose 50 mg / L. All three doses do not induce swimming speed change compared to the control group (p> 0.05).Conclusion: Subchronic exposing of D.rerio juvenilee to DDN doses of 132 mg / L and 410 mg / L did not induce changes in the swimming speed of D.rerio juvenilee. The three doses were able to increase hyperplasia of gill lamellae.
EFEK INFUSA KOMBINASI JATI BELANDA, KEMUNING, MURBEI, DAN BANGLE TERHADAP LDL DAN HDL SERUM TIKUS HIPERLIPIDEMIA Ika Rakhma Ningtyas Ayu Prasetiyo
Jurnal Kedokteran Komunitas Vol 6, No 3 (2018)
Publisher : Jurnal Kedokteran Komunitas (Journal of Community Medicine)

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Abstract

Introduction: High-fat diet (HFD) may lead to hyperlipidemic condition increasing the risk of atherosclerosis. Jati belanda, kemuning, murbei and bangle (JKMB) contain active compounds such as flavonoid, saponin, tannin, and triterpenoid which empirically used as antihyperlipidemia. This study aim to examine the effect of JKMB water extract combination on serum level of LDL and HDL in male wistar rats receiving high fat diet (HFD).Methods: Experimental laboratory, in vivo with control group post test only design. Twenty five male wistar rats were divided into 5 groups namely: a negative control (KN), a positive control (KP), and three treated groups (D1, D2, D3). The groups of KP, D1, D2, D3 treated with HFD for 12 weeks. The groups of D1, D2, D3 simultaneously received doses of 189 mg/200gBB, 378 mg/200gBB, and 756 mg/200gBB respectively everyday for 12 weeks peroral. Serum level of LDL and HDL were measured by homogeneous enzymatic colorimetric assay. Data HDLwere statistically analyzed with One-way ANOVA followed by Least Significant Difference (LSD) test. Data LDL were statistically analyzed with kruskall walis test followed by mann whitney test.Results: Levels of LDL in the KP group was higher than KN group (p<0,05). LDL dose group 378 mg / 200gBB and 756 mg / 200gBB lower than the KP group but not significant (p> 0.05) The levels of HDL in the KP group was lower than the KN group, but not significantly (p>0,05). All the doses of the given water extract JKMB did not significantly increase HDL (p>0,05).Conclusion: Administration of JKMB infusion has no effect on LDL reduction and HDL increase in HFD-treated mice.

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