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Ivandini Tribidasari A.
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Makara Journal of Science
Published by Universitas Indonesia
ISSN : 23391995     EISSN : 23560851     DOI : https://doi.org/10.7454/mss
Core Subject :
Makara Journal of Science publishes original research or theoretical papers, notes, and minireviews on new knowledge and research or research applications on current issues in basic sciences, namely: Material Sciences (including: physics, biology, and chemistry); Biochemistry, Genetics, and Molecular Biology (including: microbiology, physiology, ecology, taxonomy and evolution); and Biotechnology.
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Articles 26 Documents
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Search results for , issue "Vol. 10, No. 1" : 26 Documents clear
PENGEMBANGAN DATABASE MIKROORGANISME INDIGENOS INDONESIA Sjamsuridzal, Wellyzar; Oetari, Ariyanti; Hertono, Gatot F.; Sitaresmi, Sitaresmi
Makara Journal of Science Vol. 10, No. 1
Publisher : UI Scholars Hub

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Abstract

Development of Database for Indigenous Indonesian Microorganisms. The objective of the research is to create and develop a database of indigenous Indonesian microorganisms based at the University of Indonesia. Development of the database of indigenous Indonesian microorganisms was carried out in several stages, i.e. data identification, database design, programming, data entry, testing and debugging, and repairing and maintenance. Development of the database utilized the licensed software of General Public License (GPL), which include Linux RedHat 9.0 (operating system), Apache ver. 2.20 (web server), MySQL ver. 4.2 (database server), and PHP ver. 4.3 (web interface programming language). The result of this research is a database named UI Bioinfo which has the following facilities: online catalog search for UICC (University of Indonesia Culture Collection) strains collection and sequence homology search utility through BLAST (Basic Local Alignment Search Tool). Integrated information on strains collection was first carried out on the yeast collection. At present, UI Bioinfo contains information for 297 strains that includes isolation data, morphological descriptions, physiology-biochemical characteristics, and images. Moreover it also contains sequence data from the large subunit (LSU) ribosomal RNA gene and the internal transcribed spacer (ITS) regions. UI Bioinfo can be accessed from the following site: http://152.118.162.250/bio/. Future development will be addition of data from the other collections in UICC
A STUDY OF CLAY-EPOXY NANOCOMPOSITES CONSISTING OF UNMODIFIED CLAY AND ORGANO CLAY Juwono, Ariadne; Edward, Graham
Makara Journal of Science Vol. 10, No. 1
Publisher : UI Scholars Hub

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Abstract

Clay-epoxy nanocomposites were synthesized from DGEBA resin and montmorillonite clay with an in-situ polymerization. One type of untreated clay and two types of organo clay were used to produce the nanocompsoites. The aims of this study were to examine the nanocomposite structure using different tools and to compare the results between the unmodified clay and modified clays as nanofillers. Although diffractogram in reflection mode did not show any apparent peak of both types of materials, the transmitted XRD (X-Ray Difraction) graphs, DSC (Differential Scanning Calorimeter) analysis and TEM (Transmission Electron Microscope) images revealed that the modified clay-epoxy and unmodified clay-epoxy provides different results. Interestingly, the micrographs showed that some of the modified clay layers possessed non-exfoliated layers in the modified clay-epoxy nanocomposites. Clay aggregates and a hackle pattern were found from E-SEM images for both types of nanocomposite materials. It is shown that different tools should be used to determine the nanocomposite structure.
PENGEMBANGAN PERANGKAT LUNAK SIMULASI KOMPUTER SEBAGAI ALAT BANTU DALAM ANALISIS FARMAKOKINETIK Handari, Bevina D; Djajadisastra, Joshita; Silaban, Denny Riama
Makara Journal of Science Vol. 10, No. 1
Publisher : UI Scholars Hub

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The Development of a Computer Simulation Software as a Tool in Pharmacokinetics Analisys. This research uses mammilary model (one compartment and two compartments) as compartment model in which a single drug administration is given via oral and intravenous. Mathematical modeling in differential equations can be derived from a pharmacokinetics model. The solutions are pharmacokinetics variables and parameters that can be solved using some mathematical and numerical methods such as Laplace transformation, residual method, superposition principle, trapezoidal rule and some solving methods in differential equations.To overcome manual calculation and to visualize a drug’s dynamics in the graph form, a computer simulation software based on Visual Basic has been built. The simulation results show that any particular sample data plasma can be checked whether it is given orally or injection and has a tendency to be compatible with an assumption of one compartment or two compartments. For urin data, the software capability is still limited only for one compartment. However, it can checked if the corresponding data is given via oral or injection. So the simulations show that pharmacokinetics variables and parameters will have individual effects
REACTIONS OF CISPLATIN HYDROLYTES WITH THIOLS. 3: REACTIONS OF cis-[Pt(15NH3)2(H2O)2] 2+ WITH GLUTATHIONE Hadi, Hadi
Makara Journal of Science Vol. 10, No. 1
Publisher : UI Scholars Hub

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Abstract

The reaction of cis-[Pt(15NH3)2(H2O)2] 2+ (3) with glutathione (GSH) was investigated in aqueous solution. In this reaction, the ammine in the platinum complex formed was liberated. Surprisingly two chelate rings were observed, six-membered-S,O-chelate ring complex cis-[Pt(15NH3 )2 (SG-S,O) (7) and five-membered-S,N-chelate ring complex cis-[Pt(15NH3 )2 (SG-S,N)] (8). The bis (thiolate) platinum(II) complex, cis-[Pt(15NH3 )2 (SG)2 ] (9) was always present in this reaction in any mole ratio used. The dinuclear sulphur-bridged complex (10), giving a broad peak in 15N NMR, was only present in very tiny amounts.
PENGARUH KELEMBABAN TERHADAP SIFAT OPTIK FILM GELATIN Maddu, Akhiruddin; Modjahidin, Kun; Sardy, Sar; Zain, Hamdani
Makara Journal of Science Vol. 10, No. 1
Publisher : UI Scholars Hub

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Humidity Dependence of Optical Properties of Gelatin Films. Humidity dependence of optical properties of gelatin films prepared by casting technique has been investigated. Gelatin films was investigated its optical properties to varied humidity condition. Optical responses investigated are optical transmission and absorption at visible light spectrum measured utilizing a UV-Vis (Ultraviolet – Visible) spectrophotometer. The results of optical transmittance and absorbance obtained shows an optical response of gelatin films in widely visible light spectrum within range 530 – 680 nm, with most clearly response in a spectrum band in 580 – 650 nm. Different humidity treatment cause a significantly change of optical characteristics, that is the transmittance and absorbance change in to humidity. Transmittance of gelatin films increase with increasing humidity in a range 580 – 650 nm, in contrast with absorbance that is decrease with increasing humidity. Plot of transmission and absorption intensity with varied humidity from 37%RH to 99%RH at 610 nm exhibited a good linearity. Two samples showed same characteristics
PRODUKSI BETA-1,3 GLUKAN DARI Agrobacterium DAN AKTIVITAS PENYEMBUHAN LUKA TERBUKA PADA TIKUS PUTIH Kusmiati, Kusmiati; Rachmawati, Fitria; Siregar, Syafrida; Nuswantara, Sukma; Malik, Amarila
Makara Journal of Science Vol. 10, No. 1
Publisher : UI Scholars Hub

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Production of beta-1,3 glucan from Agrobacterium and its wound healing activity on white rat. The objective of this study was to determine the activity of beta-1,3 glucan product extracted from local Agrobacterium sp Bro 1.2.1, both wild-type and mutant-type, on opened-wound healing process. Beta-1,3 glucan product was extracted by precipitation, and the purification was carried out by column chromatography as KCl gradient fractions. In this study, white Sprague Dawley rats were employed, and have been treated for opened-wound condition. Seven groups were performed in this experiment, i.e. the negative control, the positive control employing povidone iodine, the two groups of two commercial beta-1,3 glucan with 0,02 mg/4 cm2 each, and the last three groups of beta-1,3 glucan as the test group with 0,02 mg/4 cm2, 0,10 mg/4 cm2 and 0,50 mg/4 cm2, respectively. The result showed significant differences of wound-healing activity performing statistical analysis of the least significance between the negative control, the positive control, as well as the highest dose of the test group of beta-1,3 glucan, at the dose of 0,5 mg/4 cm2 (p<0.05).
DISTRIBUSI LOGAM BERAT DALAM AIR DAN SEDIMEN DI PERAIRAN MUARA SUNGAI CISADANE Rochyatun, Endang; Kaisupy, M Taufik; Rozak, Abdul
Makara Journal of Science Vol. 10, No. 1
Publisher : UI Scholars Hub

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Heavy Metallic Element Distribution in Cisadane River Estuary’s Water and Sediment. Observation of heavy metallic elements in Cisadane River Estuary has been done in July and November 2005. The results show that heavy metallic elements content in seawater is lower and still below the treshold value stated by government for fisheries. There was an indication of heavy metallic elements on sediment. Distribution of Pb on July and of Cu on November 2005 were found higher near the coast and decrease towards the sea, and commonly were found in front of estuary such as Cisadane, Muara Saban and Tanjung Pasir. High Pb and Zn distributions on November 2005 were found only in front of Cisadane estuary. Cd distribution of Cisadane estuary was constant at all station but did not show any correlation with the distance of station and estuary. The Cd content on July and November 2005 is lower than 0,001 ppm. Generally, heavy metallic elements content have a uniform distribution at all stations inspite of its distance to estuary
BIODIVERSITAS EKHINODERMATA DI PERAIRAN PANTAI TAKOFI, PULAU MOTI – MALUKU UTARA Yusron, Eddy
Makara Journal of Science Vol. 10, No. 1
Publisher : UI Scholars Hub

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Echinoderm Biodiversity in the Takofi Coastal Waters, Moti Island, North Maluku. A total of 22 echinoderm species were found in Takofi waters, North Maluku. They were represented by 6 species of holothuroidea, 4 species of asteroidea, 5 species of echinoidea and 7 species of ophiuroidea. The Ophiuroidea were relatively common in seagrass area. The quantitative analysis on the abundance data revealed the highest diversity index of faunal assemblage at station II (H’=1.19). The highest evenness index was exhibited by the echinoderms from station III (J = 0.99), while the highest species richness was represented by them from station I (D = 1.22).
PENGEMBANGAN DATABASE MIKROORGANISME INDIGENOS INDONESIA Sjamsuridzal, Wellyzar; Oetari, Ariyanti; Hertono, Gatot F.; Sitaresmi, Sitaresmi
Makara Journal of Science Vol. 10, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Development of Database for Indigenous Indonesian Microorganisms. The objective of the research is to create and develop a database of indigenous Indonesian microorganisms based at the University of Indonesia. Development of the database of indigenous Indonesian microorganisms was carried out in several stages, i.e. data identification, database design, programming, data entry, testing and debugging, and repairing and maintenance. Development of the database utilized the licensed software of General Public License (GPL), which include Linux RedHat 9.0 (operating system), Apache ver. 2.20 (web server), MySQL ver. 4.2 (database server), and PHP ver. 4.3 (web interface programming language). The result of this research is a database named UI Bioinfo which has the following facilities: online catalog search for UICC (University of Indonesia Culture Collection) strains collection and sequence homology search utility through BLAST (Basic Local Alignment Search Tool). Integrated information on strains collection was first carried out on the yeast collection. At present, UI Bioinfo contains information for 297 strains that includes isolation data, morphological descriptions, physiology-biochemical characteristics, and images. Moreover it also contains sequence data from the large subunit (LSU) ribosomal RNA gene and the internal transcribed spacer (ITS) regions. UI Bioinfo can be accessed from the following site: http://152.118.162.250/bio/. Future development will be addition of data from the other collections in UICC
A STUDY OF CLAY-EPOXY NANOCOMPOSITES CONSISTING OF UNMODIFIED CLAY AND ORGANO CLAY Juwono, Ariadne; Edward, Graham
Makara Journal of Science Vol. 10, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Clay-epoxy nanocomposites were synthesized from DGEBA resin and montmorillonite clay with an in-situ polymerization. One type of untreated clay and two types of organo clay were used to produce the nanocompsoites. The aims of this study were to examine the nanocomposite structure using different tools and to compare the results between the unmodified clay and modified clays as nanofillers. Although diffractogram in reflection mode did not show any apparent peak of both types of materials, the transmitted XRD (X-Ray Difraction) graphs, DSC (Differential Scanning Calorimeter) analysis and TEM (Transmission Electron Microscope) images revealed that the modified clay-epoxy and unmodified clay-epoxy provides different results. Interestingly, the micrographs showed that some of the modified clay layers possessed non-exfoliated layers in the modified clay-epoxy nanocomposites. Clay aggregates and a hackle pattern were found from E-SEM images for both types of nanocomposite materials. It is shown that different tools should be used to determine the nanocomposite structure.

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