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Test of ?-Amylase Inhibition Activity in Ethanol Extract of Fennel Leaves (Foeniculum vulgare Mill.) Using Elisa Reader
Dwi Bagus Pambudi;
Nuniek Nizmah Fajriyah;
Retno Aulia Maharisti
Urecol Journal. Part C: Health Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY
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DOI: 10.53017/ujhs.1
Fennel has been cultivated in Indonesia as a spice and medicinal plant. Fennel can produce fennel oil, which is the result of distillation from dry and ripe fennel fruit powder, while fennel leaves are mainly cooked to make vegetables. The ?-amylase enzyme plays an important role in the breakdown of oligosaccharides and disaccharides into monosaccharides so that they are ready for absorption. Inhibition of the ?-amylase enzyme can delay and prolong the digestion time of carbohydrates, causing a decrease in the rate of glucose absorption and preventing an increase in postpandrial plasma glucose levels. Therefore, this study aims to investigate the ethanol extract of fennel leaves (Foeniculum vulgare Mill.) Against the inhibitory activity of the ?-amylase enzyme using Elisa Reader. The experimental research method was applied to test the ethanol extract of secondary metabolite compounds from fennel leaves against the inhibition of ?-amylase enzyme activity. The results showed that the IC50 value in the fennel leaf extract was 1.432 ?g/mL while the IC50 acarbose as a comparison was 3.340 ?g/mL. In conclusion, the ethanol extract of fennel leaves can be used to reduce blood sugar levels.
Psychological and Environmental Support: An Important Complement to Controlled Antiretroviral Therapy for HIV Patients
Setiyo Budi Santoso;
Heni Lutfiyati;
Ulfahishofi Hanifah Afifi;
Shellyta Ratnafuri
Urecol Journal. Part C: Health Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY
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DOI: 10.53017/ujhs.13
This article presents a quality of life profile for HIV patients who have undergone controlled antiretroviral therapy. Specifically, researchers reviewed the unique needs of research subjects for psychological and environmental support. The research took place at the Regional General Hospital KRT Setjonegoro Wonosobo, involving 68 research subjects. All study subjects were HIV patients undergoing controlled antiretroviral therapy (outpatient) with a duration of more than six months and were aged more than 15 years. Investigation of the quality of life profile used the Indonesian version of the WHOQOL-HIV Bref questionnaire. The results showed that HIV patients who underwent controlled therapy had a higher quality of life score than general HIV patients. Antiretroviral treatment has helped them have physical qualities, independence, spiritual side, and social abilities in living life. Even so, they need psychological intervention and environmental support to have consistent quality of themselves. Health workers involved in managing HIV patients need to provide professional interventions to improve their ability to concentrate and ensure that they are always comfortable with their physical condition. Further, there is a need for cooperation by relationships (family, friends, community) and health workers to ensure that HIV patients do not experience financial difficulties, enjoy time in a relaxed manner, and feel safe as part of the environment society in general.
Product Development of Anti Acne Gel: Combination of White Turmeric Rhizome Ethanol Extract (Curcuma Mango Val) and Galangal Rhizome Ethanol Extract (Alpinia Galanga)
Imron Wahyu Hidayat;
Retna Tri Astuti;
Tiara Mega Kusuma
Urecol Journal. Part C: Health Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY
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DOI: 10.53017/ujhs.42
White turmeric rhizome (Curcuma mango Val) and galangal rhizome (Alpinia galanga) have been widely studied to have antibacterial activity. One of the causes of acne is bacteria, such as Staphylococcus epidermidis. The purpose of this study was to determine the minimum inhibitory concentration of the ethanol extract of white turmeric (Curcuma mangga Val) and galangal (Alpinia galanga) rhizome against acne-causing bacteria and its effectiveness after it was formulated in gel form. Simplicia was extracted by maceration method using ethanol 96% solvent. The extract was formulated in the form of a gel with various concentrations of CMC Na. The results of the gel antibacterial evaluation showed that the ethanol extract gel of white turmeric rhizome (Curcuma mangga Val) and galangal rhizome (Alpinia galangal) showed antibacterial activity against S. epidermidis bacteria.
The Effect of Balance Exercise (Forward Stepping) on The Risk of Falling in the Elderly
Esri Rusminingsih;
Marwanti Marwanti;
Endang Sawitri;
Apriliana Dwi Cahyani
Urecol Journal. Part C: Health Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY
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DOI: 10.53017/ujhs.43
Falling is a common occurrence in the elderly and the risk of falling increases with age. The elderly will experience a physical deterioration in the musculoskeletal system, which causes a decrease in balance, making them prone to falling. Impaired balance is the main cause of the risk of falls in the elderly because of visual, vestibular and somatosensory disorders. The risk of falling in the elderly can lead to complications of fractures and even death. Elderly balance exercise can be used as an effort to improve the quality of life of the elderly in the community. This study aims to determine the effect of balance training (forward stepping) on ??the level of risk of falling in the elderly. The research design used a pre-experiment with the One-Group Pretest-Posttest Design. The sampling technique used random sampling with a total of 16 respondents with criteria over 65 years of age, independent mobility and not experiencing hearing and vision problems. The intervention was given in the form of forward stepping balance exercises 3 times a week for 4 weeks with a duration of 15 minutes. Measuring the risk of falling using the Time Up and Go Test (TUGT). The results showed that the mean age of the elderly was 72.38 ± 3.46 years, with 12 more elderly women (75%) than men. The risk of falling before being given training in the elderly was included in the light category with an average TUGT value of 17.06 seconds and after training there was a decrease to an average of 13.24 seconds. The Wilcoxon Test shows the effect of balance training (forward stepping) on ??the risk of falling in the elderly with p-value = 0.000 <0.05. Conclusion: The results of this study indicate that balance training (forward stepping) can reduce the risk of falls in the elderly.
The Effect of Core Stabilization Exercise on Chronic Low Back Pain Reduction: Critical Review
Wahyuni Wahyuni;
Muhammad Afif Robiatul Azis
Urecol Journal. Part C: Health Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY
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DOI: 10.53017/ujhs.45
Background: Low back pain (LBP) is a condition of low back pain. Pain that occurs in low back pain is not a disease or a diagnosis but a term for pain that is felt in the affected anatomic area with various variations in the pain duration. In some instances, the initial pain may continue over three months and eventually progress to chronic low back pain (CLBP). Objective: This study was to determine the effect of pain reduction after core stabilization exercise (CSE) on chronic low back pain based on the available literature and to determine the type of core stabilization exercise on chronic low back pain based on the existing literature. Methods: This study used a critical review study. Results: From the results of this study, eight out of 148 articles matched the inclusion criteria. Eight articles were used as the basis for the study, which was continued for the appraisal stage. The appraisal results show that six articles have a Quartile 1 (Q1) value and two articles have a Quartile 2 (Q2) value. The PEDro scale assessment gets seven articles with a low bias (the PEDro score> 5), and 1 article has a high bias (the PEDro score?5). Conclusion: Based on the results of studies that have been conducted on the effect of core stabilization exercise on pain reduction in chronic low back pain, based on studies in the existing literature, it can be concluded that core stabilization exercise affects reducing pain in chronic low back pain.
Test of ?-Amylase Inhibition Activity in Ethanol Extract of Fennel Leaves (Foeniculum vulgare Mill.) Using Elisa Reader
Dwi Bagus Pambudi;
Nuniek Nizmah Fajriyah;
Retno Aulia Maharisti
Urecol Journal. Part C: Health Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY
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DOI: 10.53017/ujhs.1
Fennel has been cultivated in Indonesia as a spice and medicinal plant. Fennel can produce fennel oil, which is the result of distillation from dry and ripe fennel fruit powder, while fennel leaves are mainly cooked to make vegetables. The ?-amylase enzyme plays an important role in the breakdown of oligosaccharides and disaccharides into monosaccharides so that they are ready for absorption. Inhibition of the ?-amylase enzyme can delay and prolong the digestion time of carbohydrates, causing a decrease in the rate of glucose absorption and preventing an increase in postpandrial plasma glucose levels. Therefore, this study aims to investigate the ethanol extract of fennel leaves (Foeniculum vulgare Mill.) Against the inhibitory activity of the ?-amylase enzyme using Elisa Reader. The experimental research method was applied to test the ethanol extract of secondary metabolite compounds from fennel leaves against the inhibition of ?-amylase enzyme activity. The results showed that the IC50 value in the fennel leaf extract was 1.432 ?g/mL while the IC50 acarbose as a comparison was 3.340 ?g/mL. In conclusion, the ethanol extract of fennel leaves can be used to reduce blood sugar levels.
Psychological and Environmental Support: An Important Complement to Controlled Antiretroviral Therapy for HIV Patients
Setiyo Budi Santoso;
Heni Lutfiyati;
Ulfahishofi Hanifah Afifi;
Shellyta Ratnafuri
Urecol Journal. Part C: Health Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY
Show Abstract
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Download Original
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Original Source
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Check in Google Scholar
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DOI: 10.53017/ujhs.13
This article presents a quality of life profile for HIV patients who have undergone controlled antiretroviral therapy. Specifically, researchers reviewed the unique needs of research subjects for psychological and environmental support. The research took place at the Regional General Hospital KRT Setjonegoro Wonosobo, involving 68 research subjects. All study subjects were HIV patients undergoing controlled antiretroviral therapy (outpatient) with a duration of more than six months and were aged more than 15 years. Investigation of the quality of life profile used the Indonesian version of the WHOQOL-HIV Bref questionnaire. The results showed that HIV patients who underwent controlled therapy had a higher quality of life score than general HIV patients. Antiretroviral treatment has helped them have physical qualities, independence, spiritual side, and social abilities in living life. Even so, they need psychological intervention and environmental support to have consistent quality of themselves. Health workers involved in managing HIV patients need to provide professional interventions to improve their ability to concentrate and ensure that they are always comfortable with their physical condition. Further, there is a need for cooperation by relationships (family, friends, community) and health workers to ensure that HIV patients do not experience financial difficulties, enjoy time in a relaxed manner, and feel safe as part of the environment society in general.
Product Development of Anti Acne Gel: Combination of White Turmeric Rhizome Ethanol Extract (Curcuma Mango Val) and Galangal Rhizome Ethanol Extract (Alpinia Galanga)
Imron Wahyu Hidayat;
Retna Tri Astuti;
Tiara Mega Kusuma
Urecol Journal. Part C: Health Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY
Show Abstract
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Download Original
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Original Source
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Check in Google Scholar
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DOI: 10.53017/ujhs.42
White turmeric rhizome (Curcuma mango Val) and galangal rhizome (Alpinia galanga) have been widely studied to have antibacterial activity. One of the causes of acne is bacteria, such as Staphylococcus epidermidis. The purpose of this study was to determine the minimum inhibitory concentration of the ethanol extract of white turmeric (Curcuma mangga Val) and galangal (Alpinia galanga) rhizome against acne-causing bacteria and its effectiveness after it was formulated in gel form. Simplicia was extracted by maceration method using ethanol 96% solvent. The extract was formulated in the form of a gel with various concentrations of CMC Na. The results of the gel antibacterial evaluation showed that the ethanol extract gel of white turmeric rhizome (Curcuma mangga Val) and galangal rhizome (Alpinia galangal) showed antibacterial activity against S. epidermidis bacteria.
The Effect of Balance Exercise (Forward Stepping) on The Risk of Falling in the Elderly
Esri Rusminingsih;
Marwanti Marwanti;
Endang Sawitri;
Apriliana Dwi Cahyani
Urecol Journal. Part C: Health Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY
Show Abstract
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Download Original
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Original Source
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DOI: 10.53017/ujhs.43
Falling is a common occurrence in the elderly and the risk of falling increases with age. The elderly will experience a physical deterioration in the musculoskeletal system, which causes a decrease in balance, making them prone to falling. Impaired balance is the main cause of the risk of falls in the elderly because of visual, vestibular and somatosensory disorders. The risk of falling in the elderly can lead to complications of fractures and even death. Elderly balance exercise can be used as an effort to improve the quality of life of the elderly in the community. This study aims to determine the effect of balance training (forward stepping) on ??the level of risk of falling in the elderly. The research design used a pre-experiment with the One-Group Pretest-Posttest Design. The sampling technique used random sampling with a total of 16 respondents with criteria over 65 years of age, independent mobility and not experiencing hearing and vision problems. The intervention was given in the form of forward stepping balance exercises 3 times a week for 4 weeks with a duration of 15 minutes. Measuring the risk of falling using the Time Up and Go Test (TUGT). The results showed that the mean age of the elderly was 72.38 ± 3.46 years, with 12 more elderly women (75%) than men. The risk of falling before being given training in the elderly was included in the light category with an average TUGT value of 17.06 seconds and after training there was a decrease to an average of 13.24 seconds. The Wilcoxon Test shows the effect of balance training (forward stepping) on ??the risk of falling in the elderly with p-value = 0.000 <0.05. Conclusion: The results of this study indicate that balance training (forward stepping) can reduce the risk of falls in the elderly.
The Effect of Core Stabilization Exercise on Chronic Low Back Pain Reduction: Critical Review
Wahyuni Wahyuni;
Muhammad Afif Robiatul Azis
Urecol Journal. Part C: Health Sciences Vol. 1 No. 1 (2021): January - June
Publisher : Konsorsium LPPM Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY
Show Abstract
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Download Original
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Original Source
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Check in Google Scholar
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DOI: 10.53017/ujhs.45
Background: Low back pain (LBP) is a condition of low back pain. Pain that occurs in low back pain is not a disease or a diagnosis but a term for pain that is felt in the affected anatomic area with various variations in the pain duration. In some instances, the initial pain may continue over three months and eventually progress to chronic low back pain (CLBP). Objective: This study was to determine the effect of pain reduction after core stabilization exercise (CSE) on chronic low back pain based on the available literature and to determine the type of core stabilization exercise on chronic low back pain based on the existing literature. Methods: This study used a critical review study. Results: From the results of this study, eight out of 148 articles matched the inclusion criteria. Eight articles were used as the basis for the study, which was continued for the appraisal stage. The appraisal results show that six articles have a Quartile 1 (Q1) value and two articles have a Quartile 2 (Q2) value. The PEDro scale assessment gets seven articles with a low bias (the PEDro score> 5), and 1 article has a high bias (the PEDro score?5). Conclusion: Based on the results of studies that have been conducted on the effect of core stabilization exercise on pain reduction in chronic low back pain, based on studies in the existing literature, it can be concluded that core stabilization exercise affects reducing pain in chronic low back pain.