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Contact Name
Murdani Abdullah
Contact Email
ina.jghe@gmail.com
Phone
+6285891498517
Journal Mail Official
ina.jghe@gmail.com
Editorial Address
Divisi Gastroenterologi, Departemen Ilmu Penyakit Dalam, FKUI/RSUPN Dr. Cipto Mangunkusumo, Jl. Diponegoro No. 71 Jakarta 10430 Indonesia
Location
Kota adm. jakarta pusat,
Dki jakarta
INDONESIA
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
ISSN : 14114801     EISSN : 23028181     DOI : -
Core Subject : Health,
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy is an academic journal which has been published since 2000 and owned by 3 Societies: The Indonesian Society of Gastroenterology; Indonesian Association for the Study of the Liver; The Indonesian Society for Digestive Endoscopy. The aim of our journal is to advance knowledge in Gastroenterology, Hepatology, and Digestive Endoscopy fields. We welcome authors for original articles, review articles, and case reports in the fields of Gastroenterology, Hepatology, and Digestive Endoscopy.
Articles 771 Documents
Colonoscopic Findings in Patients with Chronic Diarrhea at Mohammad Hoesin Hospital Palembang Imam Supriyanto; Suyata Suyata; Syadra Bardiman Rasyad; Fuad Bakry
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 14, NUMBER 2, August 2013
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (413.499 KB) | DOI: 10.24871/142201381-84

Abstract

Background: Chronic diarrhea is a common problem encountered by clinicians. Colonoscopy is a tool with high accuracy and sensitivity to depict abnormalities and has the advantage in distinguishing the abnormalities that cause chronic diarrhea. Nevertheless, the colonoscopic findings in patients with chronic diarrhea vary by age. The objective of this study is to observe abnormalities found in lower gastrointestinal tract in patients withchronic diarrhea who underwent colonoscopy and its relationship with age.Method: An observational analytic study, data retrieved from medical record of outpatient and inpatient with chronic diarrhea at Mohammad Hoesin Hospital Palembang from January 2011 until December 2012. Chronic diarrhea diagnosis was based on clinical findings, laboratory result, and colonoscopy procedure. Patients were then divided into groups based on age ( 40 and 40). Data were analyzed with SPSS 12.0.Results: There were 92 patients consisted of 56 (60.9%) male and 36 (39.1%) female. Mean age was 47.67 ± 16.83 with age interval 15-85 years. Group I of 35 (38%) patients, whereas group II of 57 (62%) patients. The colonoscopic findings were ulcerative colitis 33 (35.9%), normal 27 (29.3%), colon tumor 20 (21.7%), colitis tuberculosis 5 (5.4%), Crohn’s disease 3 (3.3%) and polyp 4 (4.3%). Based on age, the incidence of ulcerative colitis was most frequently encountered in both groups, whereas normal colon and colon tumors were encountered most in group II. No correlation was found between age and colon abnormality (p = 0.87).Conclusion: The most common finding was ulcerative colitis followed by normal colon and colon tumor. There was no correlation between age and colon abnormalities.Keywords: chronic diarrhea, colonoscopy, age
Procalcitonin Level Differences in Patients with Liver Cirrhosis Without Bacterial Infection Oska Mesanti; Rino Alvani Gani; Marcellus Simadibrata; Suhendro Suhendro
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 18, No 1 (2017): VOLUME 18, NUMBER 1, April 2017
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1464.807 KB) | DOI: 10.24871/181201715-19

Abstract

Background: Procalcitonin level can increase in patients with liver cirrhosis without bacterial infection. The aim of this study is to identify the role of procalcitonin in patients with liver cirrhosis without bacterial infection.Methods: Cross-sectional study was performed to patients with liver cirrhosis without bacterial infection. In patients, we performed procalcitonin level examination and bacterial infection identification. Further, we analysed them to know the procalcitonin level difference in patients with compensated and decompensated liver cirrhosis without bacterial infection.Results: We obtained 39 patients with liver cirrhosis without bacterial infection, male 61.5% with compensated condition found in 17 patients and decompensated in 22 patients. We found significant difference in the average of procalcitonin level in decompensated patients (0.738ng/mL ± 1.185) compared to compensated (0.065ng/mL ± 0.022).Conclusion: Procalcitonin level increased in patients with liver cirrhosis without bacterial infection. The level in decompensated patients were higher compared to compensated patients.
Spontaneous Bacterial Peritonitis Abimanyu Abimanyu
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 4, ISSUE 2, August 2003
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/42200343-47

Abstract

Infected ascites is one of the complication happened in liver cirrhotic patient in ascites. There are 5 infected ascites classifications i.e. Spontaneous Ascites Infection Consist of Spontaneous Bacterial Peritonitis, Monomicrobial Non Neurocytic Bacteriascites, Culture Negative Neurocytic Ascites, Secondary Bacterial Peritonitis and Iantrogenic Polimicrobial Bacterascites. Spontaneous Bacterial Peritonitis (SBP) is the infection in ascites without unrecognized intra abdominal infection source.The normal floras in the gastrointestinal, respiratory or urinal tract are the important infection source in SBP. As we know that normal ascites has ability to kill micro organism through phagocitosis function, opsonization, but when infected occurs ; phagocitosis function, opsonization, and MPS could be worst so that the possibility of being SBP increased. The common frequently sign and symptom of SBP are fever, abdominal pain, consciousness assault, tenderness, diarrhea, paralytic ileus, hypotension and hypothermia. Some of the invasive actions like endoscopy, variceal sclerotherapy and ligation may cause intestine flora translocation to mesenteric gland, bacterimia and infected ascites also made transmural passage intestine micro organism to ascites may cause infected ascites. Cefotaxime is the antibiotic that more frequently studied to SBP patient. The dose of cefotaxime to SBP patient show that 2 gram/6 hours and 2 gram/12 hours injected produce SBP resolution and the same survival, besides that 2 gram/8 hours injected for 5 and 10 days also show the same effectively. The antibiotic prophylaxis such as quinolon group show the effective result in liver cirrhotic with the gastroentestinal tract bleeding and low total protein (1 gram/dl ) or has the SBP experience patients.
Diarrhea in HIV Infection Juferdy Kurniawan; Marcellus Simadibrata; Teguh Karyadi; Kie Chen
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 10, ISSUE 1, April 2009
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/101200923-28

Abstract

During the last decade, there has been an increase of immunocompromized patients all around the world; that mostly due to pandemic of Human Immunodeficiency Virus (HIV) infection. Chronic diarrhea as one of common symptoms in patients with HIV infection has different etiology compared to immunocompetent patients. Initial approach of diarrhea in HIV infection may be conducted by evaluating the temporal relationship between the development of diarrhea and the administration of antiretroviral, especially the protease inhibitor agents; which is then followed by fecal analysis/examination for pathogenic bacteria and protozoa as well as endoscopy examination. Biopsy examination of intestinal mucosa is necessary for HIV enteropathy or diarrhea due to microsporidia, which is confirmed further by electron microscopy. The etiology of chronic diarrhea in HIV patients may also different, depend on the cluster of differentiation count value of all patients. Based on such differences, it is necessary  to  have  adequate  approach,   recognition  and  understanding  in the management of chronic diarrhea, especially for HIV patients. Keywords: diarrhea, infection, HI
Effectiveness of Rapid Urease Diagnostic Test in Diagnosing Helicobacter Pylori Infection in Patients with Dyspepsia in Gastrointestinal Endoscopy Centre Hasan Maulahela; Ari Fahrial Syam; Murdani Abdullah
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 21, No 2 (2020): VOLUME 21, NUMBER 2, August 2020
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (230.757 KB) | DOI: 10.24871/2122020126-129

Abstract

Background: Helicobacter pylori is one of the most important infectious agents in the world. These bacteria infect 50% of the world population. Gastritis due to H. Pylori has been associated with the incidence of peptic ulcer, B cell primary lymphoma in the stomach, and gastric carcinoma. In dyspepsia, eradication of H. Pylori helps symptoms improvement and treatment cost efficiency. This study aimed to evaluate urease test in diagnosing H. Pylori infection in dyspepsia patients. It is expected that we could obtain a scientific evidence which can become the basis of routine use of urease examination in diagnosing H. Pylori  infection.Method: This study used diagnostic study design. This study was performed in adult dyspepsia patients who underwent endoscopy examination in Gastrointestinal Endoscopy Centre Cipto Mangunkusumo General Hospital in January – November 2018. One biopsy sample was intended for rapid urease test using Helicotec which was performed according to the standard procedure and was interpreted 2 hours later. Biopsy for histopathological examination was preserved in formalin solution and sent to Histopathology Department for analysis and identification of H. Pylori bacteria. Results: Prevalence of H. pylori infection based on histopathology examination was 7.2%. From seven positive results in histopathology examination, four samples were Helocitec positive. The sensitivity and specificity of Helicotec was 57.1% and 98.9%. The positive predictive value and negative predictive value were 80% and 96.7%. Conclusion: Rapid urease examination using Helicotec is one of H. pylori diagnostic tools that is good enough to diagnose faster and cheaper. Interpretation of rapid urease test also need to consider clinical condition of patients who are tested.
17 Year Old Female Patient with Systemic Lupus Erythematosus and Ulcerative Colitis Rizky Amelia; Supriono Supriono
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 15, No 1 (2014): VOLUME 15, NUMBER 1, April 2014
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (5008.048 KB) | DOI: 10.24871/151201463-6

Abstract

Gastrointestinal manifestations are common in systemic lupus erythematosus (SLE). Although the relationshipbetween SLE with ulcerative colitis (UC) rarely obtained, SLE patients with gastrointestinal manifestations shouldpreferably be evaluated for the possibility of an inflammatory bowel disease (IBD). UC prognosis associatedwith SLE is usually good, whereas by proper diagnosis and management, the clinical output and a good life expectancy of patients will be obtainedA young female, 17 years old, who had previously been diagnosed with SLE for 5 years, came with complaintsof abdominal pain and chronic diarrhea. From the results of colonoscopy and biopsy of the intestinal mucosawas noted that in accordance with UC. After receiving treatment for 6 days, she no longer obtained complaintsof abdominal pain and diarrhea. Keywords: systemic lupus erythematosus, gastrointestinal, ulcerative colitis, inflammatory bowel disease ABSTRAKManifestasi gastrointestinal merupakan hal yang sering terjadi pada lupus eritematosus sistemik (LES).Meskipun hubungan antara LES dengan kolitis ulseratif (KU) jarang didapatkan, sebaiknya pada pasien LESdengan manifestasi gastrointestinal dilakukan evaluasi untuk kemungkinan adanya suatu penyakit inflamasiusus besar. Prognosis UC terkait LES biasanya baik, dimana dengan diagnosis dan penatalaksanaan yang tepatakan didapatkan keluaran klinis dan harapan hidup yang baik pada pasien.Seorang perempuan muda berusia 17 tahun yang sebelumnya telah terdiagnosa LES selama 5 tahun, datangdengan keluhan nyeri perut dan diare kronik. Dari hasil pemeriksaan kolonoskopi dan biopsi mukosa ususdidapatkan gambaran yang sesuai dengan KU. Setelah mendapat terapi selama 6 hari, tidak didapatkan lagi keluhan nyeri perut dan diare.Kata kunci: lupus eritematosus sistemik, gastrointestinal, colitis ulseratif, penyakit inflamasi usus besar
Helicobacter pylori, Induced Gastric Cells Apoptosis Putut Bayupurnama
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 5, ISSUE 3, December 2004
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/532004102-104

Abstract

Gastric epithelial cells apoptosis induced by Helicobacter pylori depends on microbial and host factors. Apoptosis on mitochondrial level by Bcl2 family protein is the main pathway for Helicobacter pylori induced gastric epithelial cells apoptosis, though there are roles for apoptosis through Fas receptors or TNF. Imbalance between proliferation and apoptosis gastric epithelial cells determines the risk for neoplastic transformation. Increase of gastric epithelial cells apoptosis seems to have an obligation for initiating secondary hyperproliferative response. If altruistic cellular death fails to oppose this process, uncontrollable cellular growth leading to neoplastic transformation will occur. Keywords: Helicobacter pylori, gastric cells, apoptosis
The Role of Biologics Agent in the Treatment of Inflammatory Bowel Disease Tri Hapsoro Guno; Marcellus Simadibrata
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 18, No 3 (2017): VOLUME 18, NUMBER 3, DECEMBER 2017
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (990.349 KB) | DOI: 10.24871/1832017184-196

Abstract

Inflammatory bowel disease (IBD), with major manifestations as Crohn’s disease (CD) and ulcerative colitis (UC), is a chronic intestinal inflammatory disorder with an unknown etiology which pathogensis involving multifactorial immune disorder characterized by chronic relapsing inflammation of the intestine. Management of IBD depends on stage and location of the inflammation consist of the classic conventional treatment and the more new treatment with biologics agent. Biologics agent refers to monoclonal antibodies with activity directed against specific targets involved in the pathogenesis of chronic inflammatory conditions. Advances in the understanding of the specific mechanisms of pathogenesis IBD led to the development of targeted treatment. Today there are six biologics agent approved and used as therapy and there still many other biologics agent on research progress. Many reports show positive report about efficacy for the biological therapy compared with placebo and conventional treatment for the IBD. Limited by their cost and adverse effect that possibly happened, biologics agent is still promising therapy that change the course of IBD treatment.
To Assess the Size of Esophageal Varices for Prediction of Variceal Bleeding Ari Fahrial Syam
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 12, NUMBER 1, April 2011
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/12120111-

Abstract

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Primary Gastrointestinal Tract Lymphoma David Reinhard Sumantri Samosir; Marcellus Simadibrata
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 11, NUMBER 1, April 2010
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/111201040-43

Abstract

Extranodular lymphomacanbe found in almostallorgan. One third of the cases found in gastrointestinal(GI) tract, whichisthemost commonformofextranodular lymphoma.All thesubtypesof lymphomamayoccurasprimarylesionalongingastrointestinaltract,butthemostcommonformis B-celldiffuse largecelllymphoma.DiseasesthatlinkedwithGItractlymphomaareinflammatorybowel disease, celiac disease,Helicobacter pylori, virus infection,collagen diseaseandionicradiation.This reportdescribed a40yearsoldmanwith recurrentbloodystoolandcolon lymphomawasblamedas the sourceofbleeding withitsmanagementoflymphoma. Keywords:lymphoma, gastrointestinaltract,extranodular 

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