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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 63 Documents
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Search results for , issue "Volume 09 Issue 12" : 63 Documents clear
Effect of NPK Compound Fertilizer Normal and Nano on Mineral and Protein Content of Three Species of a Piaceae Plants Dhafir A. Jameel
Journal of Global Pharma Technology Volume 09 Issue 12
Publisher : Journal of Global Pharma Technology

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Abstract

An experiment was conducted under the conditions of Al-Diwaniya governorate in a special nursery was specially constructed for the experiment during the autumn season (2016 - 2017) in order to determine the effect of adding the different levels of balanced NPK fertilizer (20-20-20) normal and nano to the soil of three species ‎of A piaceae (cumin, anise and sweet fennel) and their interference in mineral and protein content of seeds. The factorial experiment that consist of two factor and with three replicates was designed by Randomized Complete Blocks Design (RCBD); the first factor consisted of three species of A piaceae plant that above-mentioned, while second factor included seven levels of the NPK compound fertilizer balanced (control, normal NPK at recommended level, nano NPK at recommended level, normal NPK at double recommended level, nano NPK at double recommended level, Mixture NPK (Normal + Nano) at recommended level, Mixture NPK (Normal + Nano) at double recommended level).The means of the treatments was compared with a significant difference in the use of the least significant difference (LSD) at the probability level (p ≤ 0.05). The results showed the superiority of sweet fennel plant in seeds content of total phosphorus and potassium versus the superiority of cumin plant in total seeds content of nitrogen and protein. The significant effect of soil-additive fertilizers from normal and nano compound fertilizer in the increase of the majority of the studied traits and recording the highest mean in the NPK mixture at the double recommended or recommended level. The interference between factors gave the same significant effect to the superiority of the individual factors, as well as the improvement traits of more than double in some of them and the difference of response between plants depending on the type of fertilizer.Keywords: NPK; nano; a piaceae; mineral; protein.
Role of Testosterone on Waist to Hip Ratio in Women with Hirsutism Abdulsamie H. Alta'ee
Journal of Global Pharma Technology Volume 09 Issue 12
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Abstract

Hirsutism is a series problem faced women in the present days. It is usually associated with elevated levels of androgen hormones.  This study aims to investigate the role of testosterone in the waist-to-hip ratio (WHR), and body mass index (BMI) of 54 women with hirsutism and 54 healthy women match in age, in a case control study. Free testosterone and thyroid stimulated hormone (TSH) were determined using ELISA technique. WTR, BMI and hirsutism score were examined in the study groups. Free testosterone, TSH, WTR, BMI and hirsutism score found to be significantly increased when compared with control group. The result of the present study may hypothesize that testosterone has a central role in the path physiological changes occur in hirsutism, such as fat storage pattern and as consequence the HWR and the stimulation effect to induce TSH and its effect on hair growth. Keywords: Hirsutism, WTR, Testosterone, TSH, BMI.
Photo Catalytic Removal of Paraquat Dichloride Herbicide in Aqueous Solutions by Using TiO2 Nanoparticle Ayad F. Alkaim
Journal of Global Pharma Technology Volume 09 Issue 12
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Abstract In this work treatment of paraquat dichloride herbicide in wastewater using TiO2 nanoparticle as catalyst has been investigated.  Different parameters also investigated such as the effect of catalyst loading, the influence of initial dye concentration, and the effect of intensity of light in order to reach to the optimum operational conditions in which the best treated  of  paraquat dichloride herpicide. The highest removal efficiency of paraquat dichloride herbicide was indicated at 0.17 gm/100cm3 mass of aluminum oxide and 100 ppm of paraquat dichloride herbicide. photocatalytic degradation of paraquat dichloride herbicide was favorable in the 7.33 mW/cm2 light intensity. The percentage efficiency of removal paraquat dichloride herbicide equal 94. 77 %.Keywords: TiO2 nanoparticle, Paraquat dichloride herbicide, Photoefficiency.
Role of Sintering, Co-particles on Properties of Milled Al-Zn-Mg-Cu Matrix Produced via PM Haider T. Naeem
Journal of Global Pharma Technology Volume 09 Issue 12
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Abstract

In the current study, mechanically alloying has done to synthesizing Aluminum-Zinc-Magnesium-Copper-Cobalt powders via high-energy ball milling. The green compacts milled Al-Zn-Mg-Cu-Co powders were compacting using hydraulic press uniaxial at 300 MP a. The milled mixtures Al-compacts were conducted by the sintering treatments at various temperatures of 400-600 °C for 1-1.5 hours. Over all ball-milling route turn on: a ratio weight of ball-to-powder about 10:1, the speed of rotation 350 rpm; and the milling time of 8 hours. The assessment of the precipitates particles and intercom pounds of the milled Al-matrixes PM undergone conditions of sintering process were examined using the X-ray diffraction (XRD) and scanning 'electron microscopy-(SEM) with energy-dispersive X-ray spectroscopy (EDS).Outcomes of micro structural the sintered Al-PM alloys investigated having a precipitations and cobalt-compounds in the matrix during several treatments. The highest Vickers hardness recorded of Al-Zn-Mg-Cu-Co PM alloy under sintering at 600 °C.Keywords: Aluminium-Cobalt Alloys; Sintering; Hardness.
Treatment of Children with Immune Thrombocytopenia by High Dose Intravenous Dexamethasone: A Window for Improvement Ali Hadi Mahdi
Journal of Global Pharma Technology Volume 09 Issue 12
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Abstract

Introduction Immune thrombocytopenia is a hematological disorder Characterized by platelet destruction caused by auto antibodies resulting in reduction in platelet count to lower than normal range and increased bleeding tendency. Corticosteroids are considered one of the most appropriate treatment options for pediatric ITP. Methods: In this study 16 pediatric patients with acute ITP had been enrolled to evaluate their response to high pulsed dose of dexamethasone given as a 4-day course every 14 days for 4 courses by measuring their platelet counts before and after each course and along 14 months after completing the 4 courses. Results: There was a significant (p<0.0001) increase in platelet count after each cycle in comparison with platelet count before the same cycle. All the patients, at the end of fourth cycle, showed either partial or complete response and no one showed minimal or no response. Conclusion: High dose dexamethasone can be proposed as a first-line treatment for children with ITP. Repeated cycles of therapy seem to be more efficient than only one cycle to achieve a long-term response. 
Study of Histological and Histochemical Changes of Primary Visual Cerebral Cortex with Aging Process Rajaa Ali Moheiseen Al-Taee
Journal of Global Pharma Technology Volume 09 Issue 12
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Abstract

Aging has been defined as the sum of all changes produced with the passing of time, lectins are specific carbohydrate-binding proteins; they can be employed as specific probes to localize defined monosaccharide and oligosaccharides on cell surface and on cytoplasmic structures, and in an extracellular matrix. Understanding of ocular changes with aging is based on knowledge of normal ocular structure and histochemistry. For this purpose  , this study aimed : to study age-dependent histological and ultrastructural (glycoconjugates) changes in the primary visual cerebral cortex with light and fluorescence microscopy by using routine and five lectin stains  to illustrate the patterns of glycoconjugates materials during aging . This study was conducted in the department of biology /college of science, department of anatomy and histology /college of medicine of Babylon University and College of Medicine /Al-Nahrain University, with a total of 40 albino rat  .Our finding suggested: an aging appears to alter the carbohydrates components of visual cerebral cortex , The histochemical study during the preceding of age (3 , 8, 24 ,48) weeks revealed variable tempo-spatial variability of lectin bindings to the primary visual cerebral cortex  tissue, and referred that different cerebral layers have similar patterns of distribution in some aspect   , but dissimilarity in another. In conclusion, The finding of the present study clearly indicate that the lectin bindings could be an indicator for the glycoconjucate changes that play an essential role in aging process by marking cellular differentiation, cellular migration, and cellular interactions.Keywords: Aging, Lectin, Primary Visual Cerebral Cortex, Histology, Histochemistry.
High Frequency of Hemolysin Associated Genes among Staphylococcus Aureus Clinical Isolates in Iraq Ali Jaffar Saleem
Journal of Global Pharma Technology Volume 09 Issue 12
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AbstractIn current study, 120 clinical isolates of Staphylococcus aureus were collected from different hospitals in Diyala. In addtion of phenotypic method, all isolates diagnosed as S. aureus by genotypic method was done by Polymerase Chain Reaction (PCR) technique to detection nuc gene. PCR technique has been used to investigate hemolysin associated genes that encoding for hla, hlb, hlg and hld by using specific primers which showed the prevalence in percentage (95%, 79.17%, 90% and 96.67%) respectively. All isolates were found to be positive for at least two or more hemolysin genes and 69.17% of isolates were carrying all hemolysin genes.Keywords: Staphylococcus aureus, Thermo nuclease gene, Virulence genes, Alpha, Beta, Gamma and delta hemolysin.
Studying the Effect of Some Organic Sulfur Compounds as Flame Retardants for Polyester and Epoxy Resins Hanan Qais Al-Masoudi
Journal of Global Pharma Technology Volume 09 Issue 12
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In this work, five additives were used, namely; Pentane -2,3,4-trione3-[(5,6-diphenyl-6H-1,3,4-thiadiazin-2-yl)hydrazine]) (Additive I).(5-[(z)-(5,6-diphenyl-6H-1,3,4-thiadiazin-2-yl)diazenyl]-4,6dimethyl-2H-1,3-thiazin-2-amine)(AdditiveII).( (4Z,6E)-6-((Z)-(5,6-diphenyl-6H-1,3,4thiadiazin-2-yl)diazenyl)-5,7-dimethyl-2,3-dihydro-1,4-thiazepine-3 carboxylic acid)(Additive III).(6-[(5,6-diphenyl-6H-1,3,4-thiadiazin-2yl)diazenyl]-5,7dimethyl-1,3,4-thiadiazepin-2-amine) (Additive IV). (2,2- (1,4-phenylene)bis (4,5-dihydro1,thiazole-4-carboxylicacid) (Additive V).The effects of these additives on flammability of unsaturated polyester and epoxy resins have been studied. Sheets of the resins with weight percentages of (0.2, 0.4, 0.6 & 0.8 %) of the additives in dimensions (150×150×3) mm were used. Two standard test methods used to measure the flame retardation are: (ASTM: D-2863) and (ASTM: D-635).Results are obtained from these tests indicated that, additive IV has high efficiency as flame retardant, self–extinguishing (S.E.) at the percentage (0.2 %) for unsaturated polyester resin and the percentage (0.4 %) for epoxy resin. Also self- extinguishing (S.E.) at the percentage (0.4%) for additives II in unsaturated polyester resin and the (0.6%) for additives II in epoxy resin Additive V show low effect on flammability in both resinsKeywords: Sulfur compounds; Organic sulfur compounds; Additives; Flame retardants; Flammability; Unsaturated polyester resin; Epoxy resin; Thermosetting polymer.
Cytological and Microbial Investigation of Cervicitisby Endocervical Cytobrushe Smear in Some Iraqi Women Patients Eman Natiq Naji
Journal of Global Pharma Technology Volume 09 Issue 12
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This study is interested with occurrence and evaluationof cervicitis by endocervical cytobrushe smearin a sample of Iraqi women (87) who attending to the obstetrics and gynaecology outpatient  clinic in AL-Numan hospital complaining from certain symptoms for a period of 6 months. Samples were obtained from cervical and endocervicl area,divided into 2 parts; cytological and microbiological tests have been curried out . Smears were prepared in order to detect inflammation and non inflammation changes in endocervical cells .Microbiological investigation has been performed to identified suspected  pathogens; bacterial isolates; Candidaspp.and Trichomonas vaginalis. Results of cytological aspectwere shown as Increasing in number of  lymphocytes and neutrophils indicating that there is an acute inflammation besides of clusters of squamous cells in many area, squamous intraepithelial cells with nuclei were increased in size and shape in addition to containing hyperchromatic ,  membrane irregularities and thickness have appeared. On the other hand, aggregation of inflammatory cells with numerous squamous cells has been noticed.Microbiological results were represented by detection of several aerobic and aeaerobic bacteria accompanied with the infection in addition to Candidaalbicance and Candidaglabrata.A total of79 samples have been tested; 44 (55.7%)  were positivefor culturedistributed between acute29 (36.7%); and chronic;15 (18.98%).Thehighest isolation percentages were for C.albicance (15.9%), followed by different bacterial spescies ; Gardnerella vaginalis (13.6%), Staphylococcus aureus(11.3) in acute cervicitis cases,the lowest was for Lactobacillus acidophilus (0%) while in chronic cervicitis ,the highest percentage was (3.6%) for each of S.aureus ,G.vaginalis,L.acidophilus and C.albicance.Keywords: Cervicitis, Endocervical cells, Aerobic & anaerobic bacteria.
Prevalence and Some Associated Factors of Stunting Among Under-Five Children in Hilla City-Babylon Province, Iraq Alwan Baiee
Journal of Global Pharma Technology Volume 09 Issue 12
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Stunting among children  under five years of age  is a serious  health problem especially in middle and low income countries including Iraq, it is associated with high morbidity and mortality among infants and young children the objective of this study was to identify the prevalence and  some correlates of  stunting  among children under 5 years of age.A cross-sectional descriptive study was conducted, to collect primary information from  mothers  of 1000 children attending  ten randomly selected primary health care centers(five rural and five from city center) in Babylon province- AL-Hilla city during the period from  Octobar,2015 through June 2016 a pre tested questionnaire, anthropometric measurements ( length/height for age) were used  to assess children's stunting  according to -2SD length/ height for age of the World Health Organization Standard Median .The results revealed that the prevalence rate of stunting among 1000 under five children included in this study were 20.6%. Significant statistical associations were found between stunting and the following independent variables; age groups: more in the age group 24>60 months, gender: highly prevalent in boys, maternal education: highly distributed in children with poorly educated mothers, breast feeding: peaked among mixed breast feeders and among children of low family income p<0.05. In conclusion Stunting ( chronic malnutrition) in the study area is still a  concern that needs intervention by governmental and non-governmental organizations, improvements in child feeding, and better maternal education are needed to maintain the children's nutritional status to prevent and control this serious health problem .Keywords: Under weight, Stunting, Children. Under-fives, Babylon, Iraq.

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