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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 39 Documents
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Search results for , issue "Volume 10 Issue 12." : 39 Documents clear
Study of Medical and Biological Properties of Zinc Lysinate-Riboflavinate Qasim Shakir Kadhim
Journal of Global Pharma Technology Volume 10 Issue 12.
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Abstract

Biomedical houses about the Zinc-lysinitroboflavinate a new colloidal chelate structure over zinc address microelement are investigated within the case on the work. Intragastric ruler of a hundred mg/kg regarding zinc lysinate-riboflavinate in imitation of experimental animals does no longer cause signs regarding toxicological effects. Toxicological tests on zinc lysinate-riboflavinate have been conducted outdoors over the basis concerning the department about remedy and pharmacology regarding the Faculty regarding Veterinary Medicine on StSAU. The give phase arrangement about zinc lysinate-riboflavinate aqueous solutions was once investigated with the aid of the method over photon-correlation spectroscopy within the laboratories about the branch on technological know-how over Nanomaterials (NCFU, Engineering Institute).Keyword: Zinc-lysinitroboflavinate, biomedical properties, toxicological effects.
The Comparison of the Strength of the Arm Muscle between the Conventional Basket Ball Training and the Training Using the Medicine Ball Ida Ayu Kade Arisanthi Dewi
Journal of Global Pharma Technology Volume 10 Issue 12.
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Abstract

The training for athletes in the basketball sports must have the excellent biomotor skills, especially in the components of the strength of the arm muscle to be able to do the passing and shooting with the maximum movement. The basketball game uses three main elements namely passing and catching, dribling, and shooting. Until now, the training technique in order to maximize the function of the arm muscle is carried out by loading sand in the body weighing 0.5 kg. This training technique is felt to be uncomfortable when moving, thus another technique is needed to perfect it, namely the training with the medicine ball. This research is a quasi-experimental study using the randomized pre and posttest control group design. The results show that the comparison of athlete's arm muscle strength levels using the conventional training technique with the medicine ball in a row, with the result of 21.45 : 42.3, i.e., there is an increase in the strength of the arm muscle by 49.29% in the medicine ball training. The training by using the medicine ball is an exercise plan using a 1.7-kg medicine ball which can improve the conventional training method.
Impact of Pharmacokinetic Parameters Modifications of Tamsulosin Hydrochloride Controlled Release Pellets Palanisamy Vishnu
Journal of Global Pharma Technology Volume 10 Issue 12.
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Abstract

In recent years scientific and technological advancements have been made in the research and development of controlled release oral drug delivery systems by overcoming physiological adversities. There are so many oral delivery systems in that one of the advance techniques is Pellatization. Tamsulosin  controlled  release pellets prepared by pellatization method that the Tamsulosin is coated on inert suger spheres by using non perial seeds as a binder solutions and Hydroxypropylmethylcellose, Ethyl cellose, Eudragit, Triethyl citrate coating agents used for controlled release action. The prepared pellets were evaluated for Moisture content, Acid resistance Assay, and In-vitro drug release study. All the formulation exhibited assay, Moisture content with in the range given in USP. Dissolution studies revealed that formulations containing Eudragit 0.287gms coating agent Hydroxypropylmethylcellose, 0.00312gm of ethyl cellose 0.138gm Showed 100% of drug release, at the 8th hour. The concentration of coating agents Hydroxtpropylmethycellose and Ethyl cellose had an effect on in-vitro drug release had the same drug release profile when compare with US dissolution parameters, and innovator drug release. Thus, the pellets apart from fulfilling all official and other specifications and exhibited higher rate of drug release.
Technical Variables Affecting to the Production of Dried Herb Tea from Callisia Fragrans Nguyen Phuoc Minh
Journal of Global Pharma Technology Volume 10 Issue 12.
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Abstract

C. fragrans is a herbaceous plant with small white fragrant flowers and waxy leaves. C. fragrans leaves contain biologically active components such as flavonoids, neutral glycol-and phospholipids and fatty-acids.The aim of this work was to evaluate the effect of blanching, drying and preservation on the free radical scavenging activity and total phenolic content of dried Callisia fragrans. By examining on different variables of the blanching, drying; the highest phenolic and antioxidant activity inside the dried Callisia fragrans could be achieved by blanching within 10 seconds, at 95oC in the presence of citric acid 4%; size of Callisia fragrans 2.0 cm; drying at 50oC by heat pump dryer until the final moisture content 6.5%. The dried Callisia fragrans may be stable for 12 months in PET/AL/PE bag at 25oC without any deterioration. The study was of great importance to generate information about the blanching and drying process in preserving herb quality and bioactivity by avoiding the degradation of metabolites.Keywords: Callisia Fragrans, Blanching, Citric acid, Drying, Phenolic, antioxidant.
Spectrophotometry UV-Vis Technique Combined with Chemometrics for Determination Phenylbutazone and Acetaminophen In Herbal Medicines Rollando Rollando
Journal of Global Pharma Technology Volume 10 Issue 12.
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Abstract

Objective: Indonesia is known with its natural resources, one of them is abundant herbs. The herbs are basic ingredients of herbal medicine which is called jamu. Jamu started to develop since hundred years ago and passed through generation which is trusted to cure many diseases without giving any side effect. Lately, there are many cases of combining jamu with some chemical substances. The most common chemical substances used in jamu are acetaminophen and phenylbutazone. Methods: This research develops method to detect acetaminophen and phenylbutazone by using spektrofotometric UV-Vis which is combined with chemometrics. The most common chemometrics multivariate calibration used is Partial Least Square (PLS) and Principal Component Analysis (PCA). From this method, the data analysis used is R Studio software. This research generates a regression equation. Results: Based on this research, the regression equation indicates that the result is significance which can be seen from the value of P < 0.05. Besides that, the value of correlation coefficient of acetaminophen as 0.9889, and phenylbutazone as 0,9728. Conclusion:  This method can be considered as qualified and meet the requirement.
Concordance and Validity of Urinalysis Using Sysmex UX-2000, Cobas U411 and Manual Microscopic Examination Anak Agung Wiradewi Lestari
Journal of Global Pharma Technology Volume 10 Issue 12.
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Abstract

Objective: Urinalysis is important in screening, diagnosing, and monitoring the progress of certain diseases. However, the procedure takes time to finish, special skill, and lack of standardization in certain labs. This study evaluates the concordance between manual microscopic examination results to Sysmex UX-2000, and urinalysis chemical results between Sysmex UX-2000 and Cobas U411 (Roche Diagnostic), and the validity of urine sediment results between Sysmex UX-2000 and manual microscopic examination.  Methods: Eighty urine samples were analyzed using Sysmex UX-2000, Cobas u411, and manual microscopic examination. Concordance level was measured using kappa coefficient. Then we calculated the validity of Sysmex UX-2000 in sediment tests to manual microscopic examination. Results: Chemical urinalysis of Sysmex UX-2000 possesses good and very good concordance level to Cobas u411 (*weighted κ 0.65-0.91). Urine sediment tests of Sysmes UX-2000 possesses good concordance to manual microscopic examination (**weighted κ 0.76-0.77), with 86-100% sensitivity and 73-78% specificity. Conclusion: Sysmex UX-2000 has good concordance level to Cobas u411 for chemical tests urinalysis, and also good concordance and validity between Sysmex UX-2000 to microscopic examination for erythrocyte and leucocyte sediment tests.Keywords: Analytical System, Renal Diseases, Quality Assurance and Control.
Anaerobic Threshold is Significantly Enhanced by High Intensity Interval Training (HIIT) in Balinese Athletic Students Indira Vidiari Juhanna
Journal of Global Pharma Technology Volume 10 Issue 12.
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Abstract

Introduction: Anaerobic threshold is a physiological point when lactate production begins to exceed the lactate spent via oxidation process resulting in increasing amount of lactate in the circulation. It is an important aspect of sports physiology and several methods have been developed to enhance it. However, little study had conducted to evaluate the effectiveness of high intensity interval training (HIIT) in enhancing the anaerobic threshold. Method: A quasi experimental study with pre test and post test group design was conducted at Ngurah Rai Sports Building Square from January to February 2017. The subjects were randomly divided into two groups in which the first group received HIIT and the second one was the Steady State Training group performed for 2 minutes of sprint and 2 minutes of jogging for 6 weeks. Results: 24 male students were enrolled in this study with mean age 13.92±1.165 years for the first group (HIIT) and 14±1.128 years old in the second one (SST). The anaerobic threshold was significantly after the intervention (HIIT [before vs after]: 178.17±2.368 vs 197.83±3.460; SST: 177.17±1.586 vs 185.25±1.288; p: <0.05). The value difference (after-before) comparison between both groups also proved to be significantly different (HIIT vs SST: 19.67± 2.309 vs 8.08 ± 1.311; p<0.05). Conclusion: Both HIIT and SST were proved to significantly enhance the anaerobic threshold in male highschool students. However, HIIT had significantly higher enhancement compared to SST.Keywords: Anaerobic threshold, Steady State Training, lactate, high intensity interval training.
Analysis of National Lists of Essential Medicines in Ukraine and the Who Model List of Essential Medicines in the Dynamics of the Year Hanna Panfilova
Journal of Global Pharma Technology Volume 10 Issue 12.
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The article contains results of dynamic of changes of National lists of Essential medicines in Ukraine during 2001-2017 and the WHO Model list of essential medicines (1977-2017). During a long period of time the WHO International concept of model list of essential medicines was considered to have a complicated dynamic of changes of medicines. In 1977 as compared to 2017, the number of medicines increased twice. Maximum increase (455 drugs) was observed in 2011 and minimum (204 drugs) – as in 1977. The fluctuation of chain increase of the number of medicines, which were included in the WHO Model list of essential medicines from –8,0% (2013) to +22,0% (1979). In the last edition (2017) the WHO Model list of essential medicines was changed significantly, which meet up-to-date requirements of practical medicines development, and the requirements of the society as to the efficiency of medical and pharmaceutical aid. A significant fluctuations of qualitative indicators of the WHO National list of Essential medicines in Ukraine (from 215 to 780 drugs) allow us to state about the absence of a systematic approach and a relevant policy to the implementation of the WHO International concept of Essential medicines in our country to practical health protection and pharmacy. Thus, in 2008 the number of medicines included in the WHO National list of Essential medicines had 780 names, which exceeded the number of medicines of existing edition of the WHO 15th Model list of essential medicines by 1,8. We proved that the last edition (2017) of the National list of Essential medicines, which was confirmed in Ukraine based on the government program “Available medicines”, meets international requirements.Keywords: National Drug Policy, National list of Essential Medicines of Ukraine, Model list of Еessential medicines, рarmaceutical market of Ukraine, Ukraine, World Health Organization.
Biomedical and Psychosocial Treatments in Pediatrics Khudhair Khalaf Shallal
Journal of Global Pharma Technology Volume 10 Issue 12.
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Abstract

Over the past 20 years our talents about evidence-based psychological interventions for pediatric chronic pain has dramatically increased. Overall, the evidence between assist about psychological interventions because pediatric persistent discipline is strong, demonstrating fantastic psychological and behavioral effects because a range over youngsters along a thoroughness over judgment conditions. However, wide range get admission to according to tremendous psychologically-based judgment administration treatments remains a challenge for deep kids anybody go through with pain. Increasing get admission to in accordance with care then lowering chronic biomedical biases to that amount break prosperity over psychological purposes are an interior center of attention over contemporary judgment treatment interventions. Additionally, so the variety regarding evidence-based redress increase, tailoring redress according to a toddler or family’s precise wishes is increasingly more possible. This thesis intention (1) discuss the theoretical frameworks namely nicely as the particular psychological advantage yet techniques so presently preserve story as like effective retailers over change; (2) criticism and shorten tendencies within the development concerning well-researched outpatient interventions above the previous public years; yet (3) discuss after instructions for intervention lookup over pediatric chronic pain.Keywords: Chronic pain, Pediatric, Psychological intervention, Parent, Child, Evidence-based, Empirically supported.
Awareness, Attitude and Practice of Infection Control Among Clinical Year Medical Students of a Private Medical School in Malaysia Sandheep Sugathan
Journal of Global Pharma Technology Volume 10 Issue 12.
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Abstract

Objectives: The current research was planned to evaluate the awareness, attitude and practice of infection control among the clinical year medical students of a private medical school in Ipoh city, Perak State of Malaysia. This study was also aimed at any need for improving the curriculum in relation to infection control measures with an eye on reducing hospital acquired infections in future. Methods: This cross-sectional descriptive study on the awareness, attitude and practice on infection control was conducted among clinical year medical students from a private medical school in Malaysia, using a self-administered questionnaire. Results: Our study revealed that those clinical students with higher levels of attitude showed a significantly higher level of practice (p-value <0.001). The respondents having good knowledge, good attitude and correct practice were 66.7%, 57.6% and 51.5% respectively. Conclusion: Awareness of clinical medical students on infection control was quite good in this research, but it was not reflecting on attitude level and practice levels of students. There was a significant association between attitude level and practice. Gender and years of exposure in clinical practice were not significant predictors.

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