cover
Contact Name
Ayyub Harly Nurung
Contact Email
ayyub.harlynurung@umi.ac.id
Phone
+6282328980617
Journal Mail Official
jmic.sci@umi.ac.id
Editorial Address
Editor's Address: 3rd Floor Laboratory Faculty of Pharmacy, 2nd Campus of UMI: Jl. Urip Sumoharjo km. 5 , Makassar, South Sulawesi, Indonesia
Location
Kota makassar,
Sulawesi selatan
INDONESIA
Journal Microbiology Science
ISSN : 2808392X     EISSN : 28083911     DOI : https://doi.org/10.56711/jms
Core Subject : Health, Science,
Journal Microbiology Sciences (J. Mic. Sciences) receives writing in the form of research results, scientific studies and brief descriptions relating to Microbiology, such as Molecular and Microbial Epidemiology Clinical Microbiology Medical Microbiology Pharmaceutical Biotechnology and others related to Microbiology Sciencee
Articles 6 Documents
Search results for , issue "Vol 2, No 2 (2022)" : 6 Documents clear
ANTIBACTERIAL ACTIVITY TEST OF COMBINATION OF BETEL LEAF EXTRACT (PIPER BETLE) AND KERSEN LEAF EXTRACT (MUNTINGIA CALABURA) AGAINST ESCHERICHIA COLI BACTERIA T, Ardy Tanfil; Hermawati, Ema; Subagiyo, Ahmad
Journal Microbiology Science Vol 2, No 2 (2022)
Publisher : Fakultas Farmasi, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (142.658 KB) | DOI: 10.56711/jms.v2i2.829

Abstract

Escherichia coli or commonly referred to as E. coli is a Gram-negative bacteria that can cause various problems in the human body, the mechanism of resistance built by E.Coli to antibiotics is a reason for the need to look for compounds that have antibacterial potential. Betel leaf and cherry leaf are two types of plants that have the potential to have compounds that can be developed as antibacterial, this study tested the two types of plants using the disc diffusion method. The compounds identified in this plant are alkaloids, saponins, and flavonoids. These three compounds are thought to provide strong antibacterial activity in the samples, although further research is still needed to confirm this.
ANTIBACTERIAL ACTIVITY OF TEMBELEKAN LEAF (LANTANA CAMARA L.) EXTRACTS AGAINST ESCHERICHIA COLI AND STAPHYLOCOCCUS AUREUS Mubarak, Fhahri; Rante, Herlina; Putri, Pratami Yona
Journal Microbiology Science Vol 2, No 2 (2022)
Publisher : Fakultas Farmasi, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (210.422 KB) | DOI: 10.56711/jms.v2i2.831

Abstract

(Lantana camara L.) is one of the wild plants that can be used to treat various diseases such as skin diseases and diarrhea. The aim of the study to determine the antibacterial activity of ethanol extract of leaf (Lantana camara L.) can inhibit the growth of bacteria Escherichia coli and Staphylococcus aureus. This research was conducted in May 2019 at the Makassar College of Pharmacy. The phase of this research is weighing extracts, extract concentration variant manufacturing process and testing the antibacterial activity of the ethanol extract of tembelekan leaves. The analytical method used is the agar diffusion method. The results showed that the Tembelekan leaves taken from Tana Toraja Regency had a inhibitory effect on the growth of Escherichia coli and Staphylococcus aureus at concentrations of 5, 10 and 20%. The  inhibition zone formed in Escherichia coli bacteria was 8.61, 11.57 and 18.67 mm and in Staphylococcus aureus bacteria that was 9.42, 11.68 and 17.34 mm.
ANTIBACERIAL ACTIVITY OF ENDOPHYTIC FUNGI ISOLATE OF PAINTED NETTLE (Coleus scutellarioides L. Benth.) AGAINST SKIN INFECTION BACTERIA USING TLC-BIOAUTOGRAPH AND AGAR DIFFUSION METHODS Bonita S, Elivilia Oktaviana
Journal Microbiology Science Vol 2, No 2 (2022)
Publisher : Fakultas Farmasi, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (231.381 KB) | DOI: 10.56711/jms.v2i2.859

Abstract

Painted Nettle (Coleus scutellarioides L. Benth.) has properties as anti-inflammatory, antioxidant, and antibacterial. It accelerates wound healing as well. Painted nettle contains essential oils, phenols, tannins, phytosterols, alkaloids, and flavonoids. This study aimed to obtain endophytic fungi isolates that have the potential as antibacterial by TLC-Bioautography and agar diffusion methods. This research was conducted by isolating endophytic fungi of painted nettle, advanced to purification and macroscopic tests and nine pure isolates were obtained. The results of the isolate screening with the IFDI code 6 showed the highest inhibition. Furthermore, the antibacterial activity was assayed by TLC-Bioautography. The results obtained two active spots (Rf1 = 0.96; Rf2 = 0.25) against Staphylococcus aureus and Staphylococcus epidemics, three active spots (Rf1 = 0.96; Rf2 = 0.61; Rf3 = 0.25) against Psedudomonas aeruginosa. The results of the antibacterial activity assay by diffusion method obtained inhibitory zone for each bacterium, namely Staphylococcus aureus at 8.95 mm, Staphylococcus epidermidis at 8.24 mm, and Pseudomonas aeruginosa at 7.46 mm.Key words: Antibacterial, agar diffusion, endophytic fungi, skin infections, TLC Bioautography
POTENTIAL PEGAGAN LEAVES (CENTELLA ASIATICA (L.)) AS BURN HEALER AND ANTIBACTERIAL AGAINST STAPHYLOCOCCUS AUREUS Ulupalu, Fadila Fauzia Mutmaina; Azizah, Rizqi Nur; Sukmawati, Sukmawati
Journal Microbiology Science Vol 2, No 2 (2022)
Publisher : Fakultas Farmasi, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (220.995 KB) | DOI: 10.56711/jms.v2i2.862

Abstract

Pegagan leaves (Centella asiatica (L.)) in the know contain flavonoids, saponins tannin and asiaticosides which have the effect of wound healing and antibacterial. This research aims to review scientific articles related to the potential of pegagan leaves in healing burns and as an antibacterial against Staphylococcus aureus. In this study using the literature study method where articles were obtained from the Google Scholar database, then obtained 10 articles that fit the inclusion and exclusion criteria. The review results show that pegagan leaves have activity in healing burn and antibacterial activity against Staphylococcus aureus because they contain asiatic acid, saponins, flavonoids and tannins. The conclusion of this study is that pegagan leaves have the potential as wound healing of burns with an effective extract concentration of ethanol extract concentration of 25 % and ethyl acetate extract 0.33 % and pegagan leaves potentially as antibacterial to Staphylococcus aureus with effective extract concentrations, viz ethanol extract concentrations of 100 % and ethyl acetate extracts of concentrations of 70 %.
Cover Volume 2 No.2 2022 Science, Journal Microbiology
Journal Microbiology Science Vol 2, No 2 (2022)
Publisher : Fakultas Farmasi, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (384.753 KB) | DOI: 10.56711/jms.v2i2.887

Abstract

ANTIBACTERIAL ACTIVITY OF BIDARA LEAVES (Ziziphus mauritiana L.) ETHANOL EXTRACT AGAINST SOME TEST BACTERIA Nurrahma, Esti Ayu
Journal Microbiology Science Vol 2, No 2 (2022)
Publisher : Fakultas Farmasi, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (206.946 KB) | DOI: 10.56711/jms.v2i2.867

Abstract

 ABSTRACTBidara leaves (Ziziphus mauritiana L.) are one of the traditional plants that contain antibacterial compounds such as alkaloids, flavonoids, saponins, tannins and phenols. This study aimed to determine the antibacterial activity of the ethanol extract of bidara leaves (Ziziphus mauritiana L.) against several test bacteria using the agar diffusion method. This test begins with a screening test using 10 test bacteria and the result is inhibiting the growth of bacteria at a concentration of 0.1%. Then the MIC test was carried out and the result was that a concentration of 0.1% could inhibit and kill the growth of the test bacteria. Then the KBM test was carried out and the results obtained at a concentration of 12.8% could inhibit and kill Eschercia coli and Pseudomonas aeruginosa bacteria, a concentration of 6.4% could inhibit and kill Staphylococcus epidermidis and Vibrio cholerae bacteria, a concentration of 3.2% could inhibit and kill bacteria Staphylococcus aureus, Bacillus sublitis and Streptococcus mutans, a concentration of 1.6% can inhibit and kill Salmonella typhi and Propionibacterium acnes bacteria, and a concentration of 0.8% can inhibit and kill Shigella dysenteriae bacteria. Then, the antibacterial activity of the ethanol extract of bidara leaves (Ziziphus mauritiana L.) was tested using the agar diffusion method and the results showed that the ethanolic extract of bidara leaves (Ziziphus mauritiana L.) had strong potential as an antibacterial against test bacteria with the largest diameter of the inhibition zone at a concentration of 12 ,8% by 15.64 mm.Key Words: Antibacterial, Bidara Leaf (Ziziphus mauritiana L.), Agar diffusion

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