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Ahmed Abdillah
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Journal of Advances in Medicine and Pharmaceutical Sciences
Published by Lamintang Education & Training Centre
ISSN : 2964268X     EISSN : 29634253     DOI : https://doi.org/10.36079/lamintang.jamaps-xxxx.xxx
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Medicine & Pharmacology Nursing Public Health
Journal of Advances in Medicine and Pharmaceutical Sciences (JAMAPS) scope are including but not limited to: ☛ Drug ☛ Chemistry ☛ Herbal Medicine ☛ Pharmaceutical Science ☛ General and Internal Medicine ☛ Pathology and Forensic Medicine ☛ Pharmacology, Toxicology and Pharmaceutics
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 5 Documents
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Search results for , issue "Vol 4 No 1: May 2025" : 5 Documents clear
Transforming Peperomia pellucida into a Modern Pharmaceutical Tablet for Gout Zittelli, Eva Chiara; Pabayo, Prudente Estabaya; Julieta, Maria Eva; Chakthranont, Thanarat; Pongkarn, Busarakorn
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 4 No 1: May 2025
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0401.702

Abstract

Ulasimang Bato is a plant endemic to the Philippines, which is known in Latin as Peperomia pellucida. Ulasimang Bato has been widely used in the Philippines as a conventional treatment for gout. This study sought to assess the conversion of Ulasimang Bato into a contemporary pharmaceutical tablet for the treatment of gout, by examining its efficacy, safety, and use in the formal health care system alongside Allopurinol, a conventional therapy. The study was conducted from February to April 2025, a clinical trial was conducted with 300 participants, consisting of 150 people taking Ulasimang Bato tablets and 150 people taking Allopurinol, from rural areas of the Philippines. Laboratory tests validated the presence of active constituents, including flavonoids, tannins, and phenolic acids, which are thought to play a role in the anti-inflammatory, analgesic, and antioxidant properties. The study revealed that Ulasimang Bato tablets offered similar symptom relief to Allopurinol, with significantly fewer side effects, especially those related to gastrointestinal problems. This suggests that Ulasimang Bato could be a safer option for gout sufferers, especially those who cannot tolerate the side effects of Allopurinol. Furthermore, the integration of traditional medicine into the formal healthcare system shows significant community acceptance, although there are still obstacles in terms of regulation and training for healthcare practitioners. Future research should focus on extensive clinical trials to ensure the long-term safety and efficacy of Ulasimang Bato, while addressing the obstacles to its integration into the healthcare system.
Navigating the Rise of Cannabidiol: Trends, Challenges, and Future Directions Johansson, Erik; Quennerstedt, Joakim; Langer, Anneli Eva; Kullander, Stenberg
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 4 No 1: May 2025
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0401.771

Abstract

The use of cannabidiol (CBD) as an alternative treatment for chronic pain and anxiety is experiencing a rapid rise in Sweden. This study explores current trends, patient and healthcare provider perceptions, regulatory challenges, and barriers to broader CBD adoption. Employing a mixed-methods design, quantitative surveys and qualitative interviews are conducted with CBD users and healthcare professionals across various regions in Sweden. Findings indicate that CBD usage is highest in urban areas, driven by greater accessibility and wellness culture. Patients report moderate to high satisfaction, particularly for chronic pain management, although self-medication practices and lack of professional guidance are common. Healthcare providers exhibit cautious optimism, citing the need for further clinical validation and regulatory clarity. Safety concerns such as inaccurate product labeling and financial barriers, including the absence of insurance coverage for CBD, emerge as significant obstacles. Demographic analysis reveals differing usage patterns based on age but minimal gender differences. The study highlights the urgent need for standardized dosing guidelines, rigorous randomized controlled trials (RCTs), and stronger regulatory frameworks to ensure quality and equity in CBD treatment. Sweden’s progressive healthcare landscape positions it to play a leading role in global efforts to integrate CBD responsibly into mainstream medicine. Future research must bridge clinical, regulatory, and economic gaps to support CBD’s evolution as a legitimate therapeutic option worldwide.
Pharmacological Properties and Standardization of Ngoc Linh Ginseng using Ultrasonic-Assisted Extraction Phung-Van, Trung; Nguyễn Ngọc Mai Thảo; Tan Thuong, Nguyen
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 4 No 1: May 2025
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0401.778

Abstract

This study aims to evaluate the pharmacological potential and standardize the bioactive compounds of Ngoc Linh Ginseng (Panax vietnamensis) as a candidate phytopharmaceutical. The study was conducted throughout 2024 using a multidisciplinary approach, including ultrasonic extraction, chemical analysis, and pharmacological tests. Samples were collected from the Kon Tum and Quang Nam mountains, Vietnam, then extracted by the Ultrasonic-Assisted Extraction (UAE) method using ethanol-water solvents. The total saponin content obtained was analyzed using High Performance Liquid Chromatography (HPLC), resulting in a level of 28.5% with the identification of the main ginsenosides Rg1 and Re. Pharmacological activity was tested in vitro on LPS-induced RAW 264.7 cells, showing a decrease in pro-inflammatory cytokine production by up to 50% and strong antioxidant activity with an IC50 value of 25 µg/mL. In vivo tests on Wistar rats showed a hepatoprotective effect against liver damage caused by a high-fat diet. These results support the potential of Ngoc Linh Ginseng as a candidate for plant-based therapy. Further studies are recommended to explore the pharmacokinetics, clinical efficacy, and optimization of extraction techniques to expand its therapeutic applications.
Effectiveness of Balance Exercise in Reducing Fall Risk Among the Elderly Putri, Melly Anisa; Nurwanto, Ahmad; Rezkyati, Fauziyah
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 4 No 1: May 2025
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0401.814

Abstract

As individuals enter old age, they typically experience a decline in physical condition, characterized by reduced muscle strength that subsequently impairs bodily movement and functionality. These age-related physical changes often result in mobility impairments, limiting the elderly’s ability to maintain postural stability necessary for performing daily activities, and thereby increasing the risk of falls. Balance disorders are among the primary factors contributing to the elderly’s vulnerability to physical injuries from falls. This study, presented in the form of a literature review, aims to explore strategies for enhancing postural stability as a means to mitigate fall risk among older adults. Employing a scoping review methodology, this research investigates the effectiveness of balance exercise interventions in fall prevention. The literature search was conducted systematically following the PRISMA 2020 Flow Diagram guidelines and utilized three primary databases: PubMed, ScienceDirect, and SAGE Journals. The findings indicate that several exercise-based interventions, such as the Balance-Enhancing Exercise Program (BEEP), Walking Meditation, and Multi-system Physical Exercise (MPE) are effective in reducing the likelihood of falls in the elderly. It is concluded that fall risk is a significant concern among older individuals; however, this risk can be managed, particularly in those who engage in regular physical training and possess sound mental health. Among the evaluated interventions, the Self-Administered Balance-Enhancing Exercise Program (BEEP) appears to be the most effective in minimizing fall risk in elderly populations.
Acupuncture as a Complementary Therapy for Stroke Risk Reduction in Rheumatoid Arthritis Torhild, Hilde Juzeniene; Carlet, Kjennerud; Torhild, Linda Juzeniene
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 4 No 1: May 2025
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0401.818

Abstract

Rheumatoid arthritis (RA) is a chronic autoimmune disease associated with increased inflammation and increased risk of stroke. In Norway, where acupuncture is widely practiced, there is growing interest in its potential role in reducing cardiovascular complications. This study explored the effectiveness of acupuncture in reducing stroke risk factors among RA patients and its potential integration into healthcare practice. Conducted in 2024 in Oslo, Bergen, and Trondheim, the study included 200 RA patients aged 18–75 years who met the 2010 ACR/EULAR criteria and received regular acupuncture treatment. Quantitative data were collected through clinical evaluation of blood pressure, inflammatory markers (CRP, TNF-α), and stroke risk indicators at baseline and post-treatment, while qualitative data were obtained through semi-structured interviews. The findings showed significant reductions in inflammatory markers and improved blood pressure regulation following acupuncture therapy. Participants also reported improved quality of life, supporting the role of acupuncture as a complementary therapy. These findings are in line with similar studies in Sweden but offer local insights specific to Norway. Mechanistically, acupuncture appears to reduce inflammation and improve vascular health through modulation of the autonomic nervous system. This study underscores the importance of integrating acupuncture into RA management to reduce cardiovascular risk. Future studies should focus on long-term effects, larger sample sizes, and explore a wider range of cardiovascular markers. Cost-effectiveness studies and assessment of cultural acceptability are also recommended to support its inclusion in the public health care system.

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