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Journal of Advances in Medicine and Pharmaceutical Sciences
Published by Lamintang Education & Training Centre
ISSN : 2964268X     EISSN : 29634253     DOI : https://doi.org/10.36079/lamintang.jamaps-xxxx.xxx
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Medicine & Pharmacology Nursing Public Health
Journal of Advances in Medicine and Pharmaceutical Sciences (JAMAPS) scope are including but not limited to: ☛ Drug ☛ Chemistry ☛ Herbal Medicine ☛ Pharmaceutical Science ☛ General and Internal Medicine ☛ Pathology and Forensic Medicine ☛ Pharmacology, Toxicology and Pharmaceutics
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 38 Documents
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Components of Herbal Plants that Inhibit HIV in Public Health Welfare Efforts: Literature Review Safitri, Sella Dwi; Sofiyah, Shohebatuz
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 1 No 1: May 2022
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0101.424

Abstract

The highest number of HIV/AIDS sufferers is of childbearing age. Stigma, discrimination, and lack of knowledge about HIV and AIDS are the biggest problems in Indonesia in an effort to reduce the prevalence of PLWHA. Most people still do not know about the causes and modes of transmission of HIV/AIDS. Predisposition is a factor that causes a mother or baby with HIV/AIDS to have a great chance of contributing to maternal and infant mortality, which greatly determines the health status of a country's population. The number of people living with HIV is increasing in 50 countries, including Indonesia, with more than 1.8 million people newly infected with this deadly virus in 2017. Around 180,000 children (0-14 years) are infected with the HIV virus and 110,000 children die from related diseases with AIDS. The purpose of this study is to provide services that can improve health, especially for mothers and children infected with the HIV virus and improve the welfare of the community from HIV/Aids disease by being able to accept their condition, be sincere, and be able to maintain relationships with the community. By using the literature review method collected through national and international journals and research articles. The result of this literature review is to obtain the latest innovations in HIV/AIDS prevention by giving herbal medicines that can play an active role in suppressing the levels of the HIV virus in the prevention of HIV/AIDS in pregnant women and their babies, through the health services provided by medical personnel and government infrastructure, is expected to reduce the rate of HIV transmission to the mother and fetus.
The Effectiveness of Garlic Extract against Triglyceride Levels of Wistar Rats Induced by 50% Ethanol Kodariah, Liah; Mendrofa, Desmawaty
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 1 No 1: May 2022
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0101.425

Abstract

Alcohol affects the metabolism of triglycerides. Excessive intake of fat, carbohydrates, and protein can increase triglyceride levels. In addition to fat and carbohydrates, factors that can affect triglyceride levels are age, lifestyle, smoking, alcohol intake, hypertension, and liver disease. Triglyceride levels (> 200 mg/dL) raise the risk of atherosclerosis. The purpose of this study was to determine the levels of triglycerides of Wistar rats before and after induction of ethanol 50% and garlic extract therapy. The method was experimental, with a sample of 25 Wistar rats which were divided into 5 groups. G1, rats were given 50% ethanol from day 9-14, G2, rats were only given distilled water, G3, G4, and G5 treatment groups at doses I, II, and III, after ethanol administration 50% on the 9th – 14th day followed by the administration of garlic extract at a dose of 200 mg/gr BW, 400mg/gr BW and 600 mg/ gr BW, respectively. Rat blood was taken on the 8th day before administration of ethanol and garlic extract and taken again on the 15th day after administration of ethanol and garlic extract, then triglycerides were measured using a photometer. The results showed that there were significant differences in triglyceride levels in G1 with G2, G3, G4, and G5. Triglyceride levels in rats before treatment and after administration of 50% ethanol and garlic extract 200 mg/gramBW increased but were still within normal limits.
Formulation Test of Preparations Face Mist Combination of Pomegranate Peel Extract and Mangosteen Peel as an Antioxidants Lisyanti, Fatthiya; Budi, Setia; Zulfadhilah, Muhammad
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 1 No 1: May 2022
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0101.426

Abstract

Face mist is one of the cosmetics in the form of a spray, which functions as a refresher and moisturizer with the use of being directly sprayed onto the facial skin. Combining two antioxidants that work to increase the activity of preventing the effects of radiation and free radicals. Face mist is made from a combination of pomegranate peel extract (Punica granatum L.) and mangosteen peel (Garcinia mangostana L.).To obtain a formulation and evaluate the physical stability of apreparation with a face mist combination of pomegranate peel extract (Punica granatum L.) and mangosteen peel (Garcinia mangostana L.) as an antioxidant.Experimental research with One-Shoot Case Study design. Made three combination formulations of pomegranate peel and mangosteen peel extract. Then the formulation was seen from the results of the evaluation of its physical stability including organoleptic tests, homogeneity, pH, viscosity, facial moisture, spraying patterns, dry time, and antioxidant tests using the DPPH method. Analysis data One Way Anova showed that there was no significant difference in the pH, viscosity and skin moisture test. Evaluation and physical stability 21 days organoleptic test, homogeneity obtained all formulas meet the standards, pH test and dry time formula II most meet the standards, viscosity test formula III most meet the standards, formula I meets the standards for spraying pattern test, skin moisture and % inhibition highest in the antioxidant test. The preparation face mist most optimalis formula I with a ratio of pomegranate peel extract and mangosteen peel (10:15).
Thin Layer Chromatography of Secondary Metabolite Profiles and Determination of Total Flavonoid Levels of the Sawi Langit Extract that Growing on Peatlands Carolina, Feliya; Nastiti, Kunti; Rizali, Muhammad
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 1 No 1: May 2022
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0101.427

Abstract

Peatland is a type of soil with a high organic content, typically more than 65 percent organic matter, high acidity, and low nutrient content. Vernonia cinerea, also known as Sawi Langit (Vernonia cinerea L.) in Indonesia, is one of the nutritious plants. The community uses this herb to treat fevers, wounds, discomfort, and ulcers. The secondary metabolite concentration of plants in peatlands is affected by nutrients such as carbon, nitrogen, and pH. Find out the secondary metabolite content of Sawi Langit leaf extract and the total flavonoid levels that grown on peatlands. The Rf value was estimated after the descriptive observational approach was obtained from the Thin Layer Chromatography (TLC) profile of secondary metabolites with spray reagents, and the quantitative data was determined by UV-Vis spectrophotometry. Sawi Langit plants were found growing on peatlands with a pH of 3.77, N-total of 1.51%, and C-Organic of 4.16%. The best eluent for separating compounds is chloroform: methanol: water (2:5:3) for flavonoid compounds, ethyl acetate: methanol: water (16:1:2) for alkaloid compounds, chloroform: methanol (9:1) for steroid compounds, n-hexane: ethyl acetate (12:8) for terpenoid compounds, ethyl acetic: chloroform: acetic acid (15:5:2) for tannin compounds, and chloroform: ethanol: water (10:6:1) for saponin compounds. Sawi langit leaf extract has a total flavonoid concentration of 5.527 mgQE (Quersetin Equivalent)/g. Flavonoid, alkaloids, steroids, terpenoids, tannins, and saponins compounds were found in the TLC profile of Sawi Langit leaf extract, and the total flavonoid content of the leaf extract of Sawi Langit was 5.527 mgQE (Quersetin Equivalent)/g.
Relationship of Knowledge Level on Medicine Use in Hypertension Patients in the Puskesmas Sungai Tabuk Area Latif, Akmal; Kurniawati, Darini; Dona, Sismeri
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 1 No 1: May 2022
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0101.428

Abstract

Hypertension or high blood pressure is a condition in which a person experiences an increase in blood pressure if the systolic blood pressure is more than or equal to 140 mmHg and the diastolic pressure is more than or equal to 90 mmHg. In 2018 the Province of South Kalimantan was ranked first at 44.1% at the age of >18 years, which means that there was a significant increase in the number of people with hypertension in the Province of South Kalimantan. The purpose of this study was to determine the relationship between the level of knowledge and the use of drugs in hypertensive patients in the Sungai Tabuk 3 Community Health Center. The method used was a csoss-sectional or cross-sectional design. The sample is the people who live in the Sungai Tabuk Health Center area with a sample of 60 people with the Consecutive Sampling sampling technique. Using a questionnaire as a measuring tool. Data were analyzed by Spearman rho test with 95% confidence level. The result of the level of knowledge of respondents in the good category is 41 people (68.33%) with rational use of antihypertensive drugs as many as 33 people (50.00%). The results of the Spearman rho test on the relationship between the level of knowledge and the use of antihypertensive drugs obtained a significance value of 0.000 (<0.05), the correlation coefficient was 0.532 with a positive correlation direction. There is a relationship between the level of knowledge and the use of antihypertensive drugs in the community living in the Sungai Tabuk 3 Community Health Center.
Relationship of Mother Knowledge about Contraceptive Pills and Compliance the Use of Contraceptive Pills in Medan Tuntungan Nurdiana Manurung; Rizky Andriani Bakara
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 1 No 2: November 2022
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0102.441

Abstract

Knowledge is the result of "knowing" and this occurs after people have sensed a certain object. Sensing of objects occurs through the five human senses, namely sight, hearing, smell, taste and touch by themselves. The composition of the contraceptive pill contains synthetic estrogen and progestin preparations so that pregnancy can be prevented by suppressing ovulation where the hormones LH and FSH are suppressed, thickening cervical mucus, and preventing thickening of the endometrium. The prevalence of family planning according to family planning devices from active family planning participants in Indonesia is 66.20%. The dominant contraceptive methods are injections (34%) and birth control pills (17%). This study aims to determine the relationship between knowledge of women of childbearing age about birth control pills with adherence to the use of birth control pills. The research methodology in this study used analytical observation with a cross sectional approach, 40 samples by purposive sampling, in Baru Ladang Bambu, Medan Tuntungan. Based on the results of statistical analysis obtained by 40 respondents, it can be concluded that there is a relationship between the knowledge of women of childbearing age about birth control pills with adherence to the use of birth control pills, which means that the better the knowledge of women of reproductive age couples, the more obedient in the use of birth control pills.
Effect of Foot Reflection Massage on Blood Pressure Reduction in Hypertension Patients Sri Suryaningsih; Rian Tasalim; Subhannur Rahman
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 1 No 2: November 2022
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0102.442

Abstract

Hypertension is a chronic condition caused by an increase in blood pressure above normal limits. Many non-pharmacological treatments have been found to lower blood pressure, such as foot reflexology, which has a relaxing effect to improve blood circulation. Objective: To analyze the effect of foot reflexology on reducing blood pressure in hypertensive patients. Methods: foot reflexology is given which has 3 stages of administration where each treatment is given for 15-20 minutes. This research is a pre-experimental research with an approach using the One Group Pretest Posttest Design. The population in this study were hypertension sufferers in the village of Paku Alam RT 02. In taking the sample the researchers used the purposive sampling technique with a total of 15 respondents and performed foot reflexology massage. The analysis used Paired t-test. Results: the results showed that blood pressure decreased after giving foot reflexology. After processing, based on the paired t-test, p value <0.005 (0.00<0.05) was obtained, so H0 was rejected and Ha was accepted. Conclusion: The Effect of Foot Reflexology Massage on Blood Pressure Reduction in Hypertension Patients in Paku Alam Village.
Effectiveness of Slow Stroke Back Massage Using Ylang Essential Oil on Reducing Blood Pressure Hypertension Patients Normaliyanti; Muhammad Riduansyah; Eirene Eunike Meidiana Gaghauna
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 1 No 2: November 2022
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0102.443

Abstract

Hypertension is a chronic condition when the blood pressure on the increase the blood vessels. Hypertension cases in Banjar Regency in 2021 were 15,083 cases. One of the non-pharmacological therapies that can reduce blood pressure is slow stroke back massage using ylang essential oil. Slow stroke back massage using ylang essential oil can have an effect on relaxation, blood circulation and is also useful as a lowering of blood pressure. The purpose of this study was to determine the effectiveness of slow stroke back massage using ylang essential oil on reducing blood pressure in patients with hypertension in Paku Alam village. This research method uses a one group pretest posttest design. The population in this study were patients with hypertension in the village of Paku Alam RT.03. The number of samples in this study were 10 people taken by purposive sampling technique. Data were analyzed using paired t-test. The research instrument uses Standard Operating Procedures (SOP) and observation sheets. The results of this study found that blood pressure decreased after giving slow stroke back massage using ylang essential oil. The results of the analysis test obtained that the systolic p value = 0.00 < (0.05) and the diastolic p value = 0.004 < (0.05) . So it can be concluded that there is an effectiveness of slow stroke back massage using ylang ylang essential oil on reducing blood pressure in patients with hypertension in Paku Alam Village.
Description of Anxiety, Stress and Depression Levels in Post Flood Disaster Azna Yuliana; Subhannur Rahman; Rian Tasalim
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 1 No 2: November 2022
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0102.444

Abstract

The magnitude of the impact of the floods that have almost paralyzed all activities of the local community, the number of roads that are submerged, the destruction of public facilities and residential areas and the emergence of health problems make people at the disaster site feel deep trauma. This study aims to determine the description of the level of anxiety, stress and depression after the flood disaster in the people of Paku Alam Village, Sungai Tabuk District, Banjar Regency. The design of the study used descriptive. The sample of this study was taken with an accidental sampling technique of 86 people from Paku Alam Village, Sungai Tabuk District, Banjar Regency in 2022. This study used a DASS 21 questionnaire presented in the form of frequency distribution. The results showed that as many as 56 people (65.1%) were normal, as many as 10 people (11.6%) experienced mild anxiety, as many as 19 people (22.1%) experienced moderate anxiety, and as many as 1 person (1.2%) experienced severe anxiety. A total of 76 people (88.4%) were normal, as many as 9 people (10.5%) experienced mild stress, and as many as 1 person (1.2%) experienced severe stress. A total of 73 people (84.9%) were normal, as many as 4 people (4.7%) had mild depression, as many as 8 people (9.3%) had moderate depression and as many as 1 person (1.2%) had severe depression. Most of the respondents experienced normal anxiety, stress and depression about the flood disaster that occurred in Paku Alam Village, Sungai Tabuk District, Banjar Regency.
Narrative Review: Type 2 Diabetes Causes Amanda Shelvia Savitri
Journal of Advances in Medicine and Pharmaceutical Sciences Vol 1 No 2: November 2022
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.jamaps-0102.455

Abstract

Indonesia is seventh rank from 10 countries with the highest diabetic patients based on the International Diabetes Federation in 2020. One of the research result shows that women have higher risk type 2 diabetes (T2D) than men, because there is difference in body tissues where women have more adipose tissue. The purpose of this literature review is to analyze genetic factors who caused T2D. This literature research uses a narrative review design. The keywords to search the article are type 2 diabetes, type 2 diabetes factors, genetic type 2 diabetes, and factors that affect type 2 diabetes. The conclusions of causes of T2D are heredity, obesity, age, gender, education, lifestyle, food, stress, socio economic status and physical activity.

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