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Jurnal MIPA dan Pembelajarannya
Published by Universitas Negeri Malang
ISSN : -     EISSN : 27980634     DOI : https://doi.org/10.17977/um067
Core Subject : Science, Education, Engineering,
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Energy Immunology & microbiology Materials Science & Nanotechnology Mathematics
Jurnal MIPA dan Pembelajarannya (JMIPAP) is a publication that focuses on education, particularly in the areas of mathematics and natural sciences. The journal publishes articles, research papers, and other relevant manuscripts related to the teaching and learning of these subjects. It provides a platform for educators, researchers, and scholars to share their ideas, insights, and innovative teaching methods that can enhance the teaching and learning experience of students in mathematics and natural sciences. JMIPAP aims to contribute to the improvement of the quality of education in these fields by providing a space for the exchange of knowledge and ideas among its readers and contributors.
Arjuna Subject : Kimia(semua kategori) - Kimia (Lain-Lain)
Articles 236 Documents
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Ethics of Genetic Engineering and Gene Editing in Humans Salim Dakhil Rashid; Ahmed Rashid Tubena; Sabah Attwan Kazi; Salim Dakhil Rashid; Ahmed Rashid Tubena; Sabah Attwan Kazi
Jurnal MIPA dan Pembelajarannya Vol. 6 No. 1 (2026): January
Publisher : Universitas Negeri Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17977/um067v6i12026p1

Abstract

The modern biotechnology and medicine have been revolutionized in a short period by genetic engineering and gene editing technologies. Due to the invention of novel and more advanced genome-editing technologies, particularly, CRISPR-Cas9 system, the manipulation of human DNA has become more accurate and efficient than ever before. This group of technologies has enormous potential in curing and perhaps a cure to a variety of hereditary diseases such as Sickle Cell Disease, Cystic Fibrosis and Huntingtons Disease. Gene editing technologies, despite being extremely promising in the field of medical science, are linked with complex ethical, social, and legal concerns of manipulating the human genome. The paper will discuss on the ethical issue of genetic engineering and gene editing, in the case of human beings, using the available academic literature, and ethical debate. The paper covers the main ethical concerns, including the risks of the safety of the technique, the germline editing, the genetic enhancement, the social inequality, and the long-term effects of human genetic modification. The other important element of the research is the importance of ethical governance and international regulation to ensure that using gene editing technologies is responsible. The conclusions made are that although gene editing technologies are potentially very useful in the field of human health and the development of medical science, their implementation requires a strict regulation to avoid their misuse and harm the dignity of human beings. The ethical systems, community engagement and international cooperation have to play a critical role in making sure that the genetic technologies are applied in a responsible and socially beneficial way.
Effect Of Some Bean Cultivars Phaseolus Vulgaris L. In The Greenhouse on Anatomical Characteristics Abrar A. Naser; Wathik A. Aziz; Abrar A. Naser; Wathik A. Aziz; Ammar H. Saeed
Jurnal MIPA dan Pembelajarannya Vol. 6 No. 5 (2026): May
Publisher : Universitas Negeri Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The experiment was taken place at the Horticulture and Landscape Engineering Department, Tikrit University, Greenhouse Unit during the period of 2022–2023 growing season to study the effect of four bean cultivars on anatomical traits. The results revealed significant differences among the cultivars. The results showed Gia Bean cultivar outperformed the others in terms of cuticle thickness on both the upper and lower leaf surfaces, as well as epidermal cell dimensions on the upper surface. Meanwhile, the Seychelles cultivar showed greater values  in epidermal cell thickness (upper and lower surfaces), mesophyll tissue thickness, stomatal dimensions on both surfaces, and lower surface epidermal cell dimensions, in addition to having the highest stomatal frequency on the lower surface and the Ferrari cultivar was differentiated by the highest stomatal frequency on the upper surface.
Stray Dogs as a Public Health Threat: A Comprehensive Review of Hydatid Cyst (Cystic Echinococcosis) Transmission and Control Rabia Ali Aboud
Jurnal MIPA dan Pembelajarannya Vol. 6 No. 3 (2026): March
Publisher : Universitas Negeri Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17977/um067v6i32026p4

Abstract

Hydatid cyst disease, or cystic echinococcosis, is a significant zoonotic parasitic infection caused by the larval stage of Echinococcus granulosus. Dogs act as definitive hosts and play a central role in maintaining the transmission cycle, particularly in areas with large stray dog populations. Stray dogs contribute substantially to environmental contamination through the shedding of parasite eggs, increasing the risk of human infection.Humans become accidental intermediate hosts through ingestion of contaminated food, water, or direct contact with infected dogs. The disease is widely distributed in developing countries and imposes considerable health and economic burdens, especially in regions with poor slaughterhouse hygiene and limited veterinary control.This review summarizes current knowledge on the epidemiology, life cycle, transmission pathways, and risk factors of hydatid cyst infection associated with stray dogs. It also highlights clinical manifestations, diagnostic methods, and prevention strategies.Effective control requires integrated measures, including dog population management, regular deworming, improved veterinary surveillance, and public health education. The implementation of a One Health approach is essential for reducing transmission and minimizing the impact of hydatid disease on public health.
Effects of Red Light Photobiomodulation in Mitigating DNA Induced Damage Caused by Ultraviolet C in Rat Embryonic Fibroblasts Ayoob H. Obaid; Hussain S. Hasan; Marwan M. Saleh; Ayoob H. Obaid; Hussain S. Hasan; Marwan M. Saleh
Jurnal MIPA dan Pembelajarannya Vol. 6 No. 3 (2026): March
Publisher : Universitas Negeri Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17977/um067v6i32026p5

Abstract

Ultraviolet C radiation is a potent genotoxic agent that induces DNA strand breaks and cyclobutane pyrimidine dimers. Red light photobiomodulation (PBM), delivered via light-emitting diodes (LEDs) at 633–655 nm, has emerged as a promising non-invasive strategy to stimulate DNA repair. This study investigated and compared the cytoprotective efficacy of red LED irradiation applied after UVC exposure in rat embryonic fibroblast (REF) cells, using the alkaline comet assay as the primary quantitative endpoint. UVC irradiation (10 mJ/cm2) induced a significant increase in medium- and high-damage comets (p < 0.0001) relative to untreated controls. treatment strategy attenuated DNA strand breaks; however, post-irradiation PBM (UV+Red) produced a statistically significant increase in the undamaged-cell population (p = 0.0246), indicating active repair rather than mere damage mitigation. Red LED PBM holds translational potential as a safe and effective phototherapy intervention against UVC-induced genotoxicity.
Increasing The Influence of Polymers in Lithium Batteries Fahmi Yekti Waluyo; Markus Diantoro; Fahmi Yekti Waluyo; Markus Diantoro
Jurnal MIPA dan Pembelajarannya Vol. 6 No. 7 (2026): July
Publisher : Universitas Negeri Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17977/um067v6i72026p4

Abstract

Recently, there has been much innovation in the energy storage system. The famous energy storage system now is Lithium battery, due to high energy density, little capacitance lost, and efficiency. But in the way of explosion, extreme temperature, liability to explode again, and precipitate lithium that didn't evenly become bad for lithium batteries. Actually now there is much research innovation to enhance lithium batteries performance. Mostly in modification materials like synthesis, doped, and composite. And in another way, polymers also turn out to be material batteries. In 1970 some scientists discovered an innovative polymer for battery material. It's an open new view in science knowledge, especially material development of batteries. Therefore these research polymers in lithium batteries material to increase. To responses of enhancement performance of lithium batteries material, we make comparison between polymer usage and non-polymer usage (synthesis, doped, composite) for lithium batteries. The result from non-polymer usage showed composite had highest specific capacity(1349 mAh.g-1), but doped also had high specific capacity even though not more than composite methods. On the other hand, the use of polymers showed the highest specific capacity of 2237 mAh.g-1. However, the use of non-polymers was far superior, providing higher average specific capacity values. Therefore, the use of common materials modified through synthesis, doping, and composites remains the best way to improve the performance of lithium batteries today.
Efficiency Evaluation of Weibull Distribution Parameter Estimators for Failure Data: A Comparative Study Using Simulation Experiments Hayder Sami Alwan
Jurnal MIPA dan Pembelajarannya Vol. 6 No. 6 (2026): June
Publisher : Universitas Negeri Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17977/um067v6i62026p5

Abstract

The purpose of this study is to assess the efficiency of parameter estimation methods of Weibull distribution for the analysis of failure data and reliability data. This is done by comparing three approaches for estimation: Maximum Likelihood Estimation (MLE), Method of Moments (MoM) and Least Squares Method (LSM). The significance of this study lies in the fact that the Weibull distribution is widely used to model failure times because of its high flexibility and it can be used to model many failure rate patterns. The method that is used as a simulation method is carried out by applying software called Stata 17 with the programming language Mata. The two-parameter Weibull distribution was used to generate data and had different values for the shape parameter (β) and sample sizes. The performance of the estimation methods was then assessed with the help of two statistical criteria: Mean Squared Error (MSE) and Bias. The results indicate that the Mean Squared Error (MSE) and the Bias values of the Maximum Likelihood Estimation (MLE) method were smaller than the other methods in most of the cases. This means that it has a high efficiency for estimating the parameters of the Weibull distribution, especially with larger sample sizes. The results also showed that the Least Squares Method was good and close to the Maximum Likelihood Estimation method so that it can be used as an alternative method in some practical situations. The Method of Moments was found to be the least efficient method, particularly for high values of the shape parameter or for small sample sizes. This study concludes that the choice of estimation method is mainly dependent on the sample size and failure data. It also suggests that in practical applications of reliability analysis and survival data the Maximum Likelihood Estimation method should be adopted as a standard method.
Comparative Evaluation of Clove Extract and Green-Synthesized Selenium Oxide Nanoparticles for Protection Against UV-B Induced DNA Damage: A Comet Assay-Based Study Kawther Y. Mashjal; Hussain S. Hasan; Labeeb Ahmed Alzubaidi; Kawther Y. Mashjal; Hussain S. Hasan; Labeeb Ahmed Alzubaidi
Jurnal MIPA dan Pembelajarannya Vol. 6 No. 2 (2026): February
Publisher : Universitas Negeri Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17977/um067v6i22026p3

Abstract

Ultraviolet (UV) radiation is one of the major environmental factors which can be harmful for cellular DNA. It can lead to genetic mutations and damage to DNA, which can increase the risk of a variety of diseases, including cancer. The objective of the present study was to evaluate the therapeutic effects of clove extract (Syzygium aromaticum), clove-mediated selenium nanoparticles (SeNPs) and clove extract alone on UVB-induced DNA damage in mice.  UVB exposure resulted in a significant increase in DNA damage as measured by the Olive Tail Moment in the Comet assay. Post-treatment with clove extracts reduced DNA damage however, the clove mediated selenium nanoparticles showed a stronger therapeutic effect. The SeNP-treated groups, especially after 15 min exposure, showed the lowest Olive Tail Moment values, indicating a significant reduction in genotoxicity. This suggests that clove mediated selenium nanoparticles have great therapeutic potential in repairing UV induced DNA damage and improving genome stability.
Assessment of Long-Term Diabetes Medication Use and Its Effects on Osteoporosis Risk in Diabetic Patients Muayad AL-dulaimi; Muayad AL-dulaimi; Saad M. Saeed
Jurnal MIPA dan Pembelajarannya Vol. 6 No. 1 (2026): January
Publisher : Universitas Negeri Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17977/um067v6i12026p3

Abstract

Background; Diabetes mellitus is a metabolic and systematic disorder that requires individualized therapy. The disease leads to various consequences, resulting in the destruction of tissues and organs. The aforementioned outcomes also include bone mineral disorders, caused by medications as well as diet therapy and physical activity.  Objective; Assessment of osteoporosis risk in diabetic patients with  long-term diabetes medication use by detection some immunological and biochemical indicators. Material and methods; The current study was conducted in Baqubah city/ Diyala province for the period; 1/10/2024 to 1/3/2025. 50 blood samples were collected from diabetic patients with osteoporosis who went to Baqubah Teaching Hospital as well as to the outpatient clinics. Also, 30 blood samples were collected from healthy people and considered as a control group.  Serum levels of ACCP, CRP, CK-MP, Vitamin D3, calcium, and RF  in all samples were quantified by  AFIAS  Machine. Present data were programmed by SPSS v. 20.0 and Graph pad prism v.6 statistical software. Results; Present outcomes showed no significant differences (p>0.05) between males versus females and among age groups of patients. Also, current findings showed no significant differences between positivity of RF and study groups. Levels  of CRP and CK-MP were high in patients compared to controls , while levels of Vitamin D3 and  calcium were lowest in patients  than control . In contrast, present study showed no differences (p>0.05) between levels of ACCP and study groups. Based on gender, present research showed no differences between positivity RF and groups (male vs. female vs. control). The levels of CRP  and CK-MP scored highest mean level in males and lowest mean in females . On other hand, present findings showed the Vitamin D3  and calcium scored lowest level in males and highest mean in control . Finally, present study showed no differences (p>0.05) between levels of ACCP and groups (male vs. female vs. control). Conclusions;  The present study concluded the ACCP and RF indicator not play role in assessment osteoporosis in DM patients due to it isn’t levels affected by diseases, while CRP, calcium, CK-MB and vitamin D3 indicators have major role in assessment due to it is levels high affected by disease. Based on gender, present findings revealed there is variation in levels of CRP, calcium, CK-MB and vitamin D3 between males versus females due to hormonal and genetic disorders. 
Biochar-Based Materials for Water Purification: A Comprehensive Review Zeena Razaq Katoof; Noor Ulhuda Sabah Hussein; Zeena Razaq Katoof; Noor Ulhuda Sabah Hussein; Thaqeef Murtada Jawad
Jurnal MIPA dan Pembelajarannya Vol. 6 No. 1 (2026): January
Publisher : Universitas Negeri Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17977/um067v6i12026p4

Abstract

With the rapid industrialization, urbanization and agricultural developments, water pollution has emerged as one of the most critical environmental issues of the world. The traditional water treatment technologies are also costly, inefficient and have secondary pollutants. Biochar is a carbon rich material generated by thermochemical conversion of biomass in the absence of oxygen and has shown promise as a sustainable, economical adsorbent for water purification. The porous structure, high specific surface area, and large number of functional groups on the surface and tunable physicochemical properties make biochar a material that has proven to have very high potential to remove a wide range of contaminants from an aqueous environment. This review summarizes the technologies of biochar production, physicochemical properties and modification methods to improve adsorption performance. The mechanisms involved in pollutant removal, such as electrostatic interaction, ion exchange, filling the pore volume, surface complexation, and π–π interaction are critically discussed. Moreover, the application of pristine and engineered materials of biochar for heavy metal, dye, pharmaceuticals, nutrients and emerging contaminant remediation is systematically reviewed. Current problems with the large scale implementation, regeneration, environmental safety and economic feasibility are also discussed. Finally, future research directions are suggested to help the development of high-performance biochar based materials in sustainable water treatment technologies.
Laser Ablation Synthesis and Characterization of Gold-Zirconium Oxide Nanoparticles Ali Fadhil Abdulaali
Jurnal MIPA dan Pembelajarannya Vol. 6 No. 1 (2026): January
Publisher : Universitas Negeri Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17977/um067v6i12026p5

Abstract

The synthesis and characterization of gold-zirconium oxide (Au-ZrO₂) nanoparticles by Pulsed Laser Ablation in Liquid (PLAL) technique is presented. The stable colloidal suspensions of gold and zirconium nanoparticles were generated by ablation of targets made of high purity gold and zirconium, respectively, in deionized water at different laser energies. The obtained nanomaterials were deposited onto the substrates by drop-casting and then subjected to calcination to improve the crystallinity and bonding at the interface. UV–Vis spectroscopy was utilized to investigate the optical properties, which showed prominent surface plasmon resonance (SPR) peaks for Au nanoparticles and broad absorbance range characteristic of the ZrO₂ wide band gap. The crystallite size of the Au and ZrO₂ phases was determined to be ~ 14.2–14.4 nm, respectively, by X-ray diffraction (XRD) analysis, and the phases formed were found to be face-centered cubic (FCC) Au and cubic ZrO₂. The images obtained by Field Emission Scanning Electron Microscopy (FESEM) showed uniformity in morphology, the nanometric particle size and possibility of core–shell structures. Overall, the Au-ZrO₂ nanocomposites synthesized by PLAL demonstrate structural and optical properties suitable for various applications, including gas sensing, photocatalysis, and optoelectronics, highlighting the potential of PLAL for producing high-performance advanced nanomaterials.

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