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Giftania Wardani Sudjarwo
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INDONESIA
Journal of Pharmacy Science and Technology
Published by Universitas Hang Tuah
ISSN : -     EISSN : 26140993     DOI : https://doi.org/10.30649/pst
Core Subject : Health,
Medicine & Pharmacology
The Journal of Pharmaceutical Science and Technology is a journal for scientific publications on all pharmaceutical aspects including pharmaceutical science (pharmaceutical technology, pharmaceutical chemistry, pharmaceutical biology, pharmacognosy, microbiology and pharmaceutical biotechnology), community pharmacy, clinical pharmacy until explore the potential of marine biota. This journal is published twice a year to provide a means for pharmacists and other health professionals to share research results to improve the science of pharmaceuticals. The Journal of Pharmaceutical Science and Technology is intended to present the best quality research articles in pharmaceutical science, community pharmacy and clinical pharmacy to become scientific guides in fields related to science and pharmaceutical technology. This journal is a peer-reviewed journal and publishes original research articles on all aspects of science and pharmaceutical technology. This journal accepts original articles as well as for other categories such as review articles and case reports for all aspects of pharmaceutical science, pharmacy clinics and community pharmacy.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 5 Documents
 1 
Search results for , issue "Volume 4 No. 1: Desember 2023" : 5 Documents clear
A PHYTOCHEMICAL STUDY OF KENCUR (Kaempferia galanga L) ETHANOL EXTRACT AS ANTI-BACTERIAL, ANTI-INFLAMMATORY, ANTI-OXIDANT, AND ANTI-FUNGAL tobing, yauwan Tobing Lukiyono; Adriansyah, Agus Aan; Setianto, Budhi; Munawwaroh, Ahsantul; Ilmia, Fadhilatul; Wulansari, Febrianti; Rahmania, Almanda Putri
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 4 No. 1: Desember 2023
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v4i2.76

Abstract

Kaempferia galanga L or kencur is widely used as a raw material for traditional medicine (herbal medicine), phytopharmaceuticals, the cosmetics industry, spices, as well as a mixture of sauces, cigarettes in the kretek cigarette industry. Kencur or Kaempferia galanga L has anti-inflammatory activity which has been tested in acute inflammation (Kumar, 2020)The writing of this article is based on a study of literature obtained online in the form of articles, journals and other research results. The purpose of writing this article was to determine the effectiveness of the ethanolic extract of Kaempferia galanga L using the diffusion method in order to show significant inhibition on the growth of various types of microbes at a concentration of 10 L / disc as antibacterial, anti-inflammatory, antioxidant and anti-herbal. The conclusion obtained is that kencur (Kaempferia galanga L) has many benefits ethnobotanically from kempferia galanga L, but regarding its bioactivity it proves the activity of Kampferia galanga L as antifungal, anti-oxidant, anti-inflammatory and anti-bacterial.
REVIEW ARTIKEL : ANALISIS KANDUNGAN ASAM ASKORBAT PADA BEBERAPA TANAMAN Lukman, Hilmia; Shofia, Vivi
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 4 No. 1: Desember 2023
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v4i2.88

Abstract

Ascorbic acid or vitamin C is an essential organic compound for the body and has many health benefits. Vitamin C cannot be produced by the body, so it must be obtained from outside the body through food consumption. The vitamin C in plants varies considerably depending on the type, the part of the plant, and the growing environment. Vitamin C analysis can be carried out using qualitative and quantitative methods. This article review aims to review qualitative and the quantitative analysis of vitamin C using plant samples. The plants used in the study are plants that are widely consumed in Indonesia, namely matoa fruit (Pometia pinnata), water spinach (Ipomoea reptana Poir), spinach (Amaranthus spinosus), cucumber (Cucumis sativus L.), enau fruit (Arenga pinnata Merr.) and katuk leaves (Sauropus Androgynus). The qualitative analysis of vitamin C used FeCl3, KMnO4, Methylene blue and AgNO3 reagents, while the qualitative analysis uses the UV-Vis spectrophotometry method and several titration methods.
GAMBARAN POLA TERAPI OBAT PASIEN GAGAL JANTUNG DI RSUP DR. M. DJAMIL PADANG PERIODE OKTOBER-DESEMBER 2023: Description of Drug Therapy Patterns for Heart Failure Patients at RSUP Dr. M. Djamil Padang October-December 2023 period elsa, elsa marsellinda; Aulia, Dea Suci
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 4 No. 1: Desember 2023
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v4i2.89

Abstract

ABSTRACT Heart failure is a complex clinical syndrome due to functional or structural ventricular dysfunction, resulting in symptoms of left ventricular dysfunction. The goal of treating heart failure is to reduce morbidity and mortality and prevent the worsening of heart disease. The purpose of this study was to describe the pattern of heart failure drug therapy at Dr. M.Jamil Padang Hospital. Data were collected retrospectively from the medical records of heart failure patients admitted to the cardiac ward. period October to December 2023 analyzed descriptively. Results: In this study, furosemide (31.29%) was followed by ramipril (21.09%) and candesartan (15.65%). The most common drug combination therapy was a combination of three drugs (32.14%), followed by a combination of two drugs (30.36%) and a combination of four drugs (22.32%). Conclusion: based on the results of the study, it can be concluded that the most widely used therapy is furosemide, ACEI, and ARB. The most common drug combination used for heart failure patients is ARB/ACEI and diuretics.
SKRINING FITOKIMIA DAN UJI POTENSI ANTIKANKER EKSTRAK METANOL KULIT BATANG (Rhizophora mucronata (Lamk.)) MENGGUNAKAN METODE BSLT (Brine Shrimp Lethality Test) Asniyah, Asniyah; Mahmiah, Mahmiah; Sudjarwo, Giftania Wardani
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 4 No. 1: Desember 2023
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v4i2.101

Abstract

Cancer is one of the leading causes of death in the world. The main therapies for cancer include surgery, chemotherapy, radiotherapy. However, the use of chemotherapy drugs can cause side effects such as hair loss, bone marrow suppression, drug resistance. Based on these side effects, this study conducted research on natural ingredients as an alternative to cancer treatment. Rhizophora mucronata can be used as an anticancer, where people in coastal areas or around mangrove forests use mangroves as medicinal plants, and are believed to have minimal side effects so that they can be developed as traditional medicines. In this study, analysis of phytochemical screening and anticancer potential tests of methanol extract of Rhizophora mucronata stem bark was carried out from Pamurbaya, Surabaya, East Java. In this study, the BSLT (Brine Shrimp Lethality Test) method was used to test the anticancer potential with the LC50 (Letal Concentration) value as a parameter. The results of phytochemical screening of the methanol extract of Rhizophora mucronata stem bark contain tannins, saponins, alkaloids, steroids, flavonoids, anthraquinones and polyphenols and have anticancer potential with an LC50 value of 120.8656 ppm which falls into the toxic category.
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK AKAR BAKAU HITAM (Rhizophora mucronata (Lamk.)) DENGAN METODE DPPH (2,2-diphenyl-1-picrylhydrazyl) Sulistiorini, Indah; Mahmiah, Mahmiah; Sudjarwo, Giftania Wardan
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 4 No. 1: Desember 2023
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v4i2.102

Abstract

Indonesia is a country that has a variety of marine ecosystems that have a lot of potential, one of which is mangroves. Rhizophora mucronata is a species in the mangrove ecosystem in Indonesia. Rhizophora mucronata or black mangroves are plants that contain various kinds of compounds. Antioxidants play an important role in the prevention of degenerative diseases. This research is motivated by the presence of carcinogenic dangers caused by consuming synthetic antioxidants at high doses synthetic antioxidants can function as prooxidants which can increase oxidative stress and damage body cells, so it wants to explore the natural antioxidant potential of Rhizophora mucronata. Rhizophora mucronata root was chosen in this study because no one has examined the potential of this plant that grows in the Pamurbaya area, Surabaya - East Java as an antioxidant. This study aims to determine the content of secondary metabolites and antioxidant activity of the root extract of Rhizophora mucronata. In this study, the antioxidant activity test used the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The results showed that the antioxidant activity of the methanol extract of Rhizophora mucronata root had very weak antioxidant activity with an IC50 value of 2604.56 ppm. The antioxidant potential of the methanol extract of Rhizophora mucronata root has an IC value of 50 with a very weak antioxidant intensity

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