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Jurnal Penyakit Dalam Indonesia
Published by Universitas Indonesia
ISSN : 24068969     EISSN : 25490621     DOI : https://doi.org/10.7454/
Core Subject : Health,
Medicine & Pharmacology
Jurnal Penyakit Dalam Indonesia contains the publication of scientific papers that can fulfill the purpose of publishing this journal, which is to disseminate original articles, case reports, evidence-based case reports, and literature reviews in the field of internal medicine for internal medicine and general practitioners throughout Indonesia. Articles should provide new information, attract interest and be able to broaden practitioners insights in the field of internal medicine, as well as provide alternative solutions to problems, diagnosis, therapy, and prevention.
Arjuna Subject : Kedokteran - Kedokteran Internal
Articles 9 Documents
 1 
Search results for , issue "Vol. 7, No. 2" : 9 Documents clear
The Correlation between Transforming Growth Factor-Beta (TGF- β) Serum Level and Beck Depression Inventory (BDI) Score in Colorectal Cancer Patients at RSMH Palembang Apriansyah, Muhammad Ali; Syahrir, Mediarty; Rosyidi, Muhammad, Kgs; Faisyar, Ahmad
Jurnal Penyakit Dalam Indonesia Vol. 7, No. 2
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Introduction. Depression not only increase the mortality rate, but also can interfere the quality of life of colorectal cancer patients during treatment. Low levels of systemic inflammation may contribute to the development of depression. The inflammatory process can be seen by measuring serum transforming growth factor-β (TGF-β) levels and depressive symptoms using the beck depression inventory (BDI) score. This study aimed to determine the correlation between TGF-β serum levels with depression in colorectal cancer patients. Methods. Analytical observational research with cross sectional design was conducted among colorectal cancer patients who underwent chemotherapy with a BDI score ≥10 (depression) in the RSMH Palembang from June 2018 to June 2019. Serum TGF-β levels were measured by the enzyme-linked immunosorbent assay (ELISA) quantitative method. Spearman analysis was used to assess the correlation of TGF-β levels and BDI score. Results. A total of 40 subjects were included in this study with mean value of TGF-β serum was 108.14 pg/mL (SD 39.97 pg/mL). Median beck depression inventory (BDI) score was 14 (range 10-28). There was a moderate positive correlation between serum TGF-β levels and BDI score (r = 0.485; p = 0.002). Conclusion. There was a moderate positive correlation between serum TGF-β levels and BDI score in colorectal cancer patients at RSMH Palembang
The Proportion of Acute Transfusion Reaction at Outpatient Blood Transfusion Unit in Tertiary Hospital in Indonesia Zein, Ahmad Fariz Malvi Zamzam; Sukrisman, Lugyanti
Jurnal Penyakit Dalam Indonesia Vol. 7, No. 2
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Introduction. Acute transfusion reaction (ATR) is an important issue related to patient safety. The prevalence of ATR at tertiary hospital in Indonesia is 0.5%. This study was aimed to determine the proportion of ATR in outpatient blood transfusion unit at tertiary hospital. Method. This retrospective study implemented data from medical records of adult patients who underwent blood transfusion in outpatient blood transfusion unit, Cipto Mangunkusumo Hospital between August – October 2014. The blood components included packed red cells (PRC), thrombocyte concentrate (TC), fresh frozen plasma (FFP), and cryoprecipitate. We recorded the administration of premedication and ATR-related symptoms/signs. The ATR report was based on WHO classification. Results. There were 1,010 blood transfusions during the study period. The distribution of blood components were PRC (n=802, 79.4%), PC (n=74, 7.3%), FFP (n=43, 4.3%), and cryoprecipitate (n=91, 9.0%). The premedication was administered in 21 transfusions (2.1%). There were 11 ATRs with WHO category 1 (1.1%), no other categories were reported. Based on blood component, the ATR occurred predominantly in PRC transfusion (0.6%), followed by FFP (0.3%), cryoprecipitate (0.1%), and TC (0.1%), respectively. Conclusion. The proportion of ATR in outpatients blood transfusion unit at Cipto Mangunkusumo Hospital was 1.1%. All reported ATR were category 1 in this study. The ATR was predominantly in PRC transfusion.
Prediction Model of 30-Day Mortality in Elderly Patients Admitted to Geriatric Acute Ward Using Comprehensive Geriatric Assessment Domain Dwimartutie, Noto; Setiati, Slti; Wahyudi, Edy Rizal; Harimurti, Kuntjoro
Jurnal Penyakit Dalam Indonesia Vol. 7, No. 2
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Factors Associated with Late Referral in End Stage Renal Disease Patients at Dr. Cipto Mangunkusumo Hospital Lydia, Aida; Rachmaningrum, Grecia; Shatri, Hamzah; Nugroho, Pringgodigdo
Jurnal Penyakit Dalam Indonesia Vol. 7, No. 2
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Relationship between Total Session of Hyperbaric Oxygen Therapy as Adjuvant Therapy with Diabetic Foot Ulcers Improvement in Dr. Mintohardjo Naval Hospital in The Year 2016−2018 Andrisha, Naufal Hilmi; Savitri, Pritha Maya; Bustamam, Nurfitri
Jurnal Penyakit Dalam Indonesia Vol. 7, No. 2
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Introduction. Diabetic foot ulcers (DFU) are a common complication of diabetes mellitus (DM). High rates of amputation risk and mortality in DM patients with DFU as well as the use of conventional therapies that often fail to improve the DFU condition cause an adjuvant therapy such as hyperbaric oxygen therapy (HBOT) to be used. HBOT is known can facilitate wound bed closure and reduce the amputation rates in diabetic gangrene foot. This study aimed to determine the relationship between total sessions of HBOT as adjuvant therapy with an improvement of DFU patients. Method. A cross-sectional study was conducted among DFU patients who were given HBOT as adjuvant therapy in Dr. Mintohardjo Naval Hospital in the year 2016–2018. Data were collected from the medical record. The statistical analysis used in this study was the Friedman test to assess whether there was a relationship between the total session of HBOT with the DFU improvement. Wilcoxon post-hoc test was performed to provide the treatment group with the best DFU improvement. Results. There were 20 subjects in this study. To assess the best treatment group in DFU improvement, a comparison between the treatment groups under 10 sessions and above 10 sessions with other treatment groups was made. Friedman test with p-value = 0,001 indicates that there was a relationship between total session of HBOT as adjuvant therapy with an improvement of DFU. Based on Wilcoxon post-hoc test, the treatment groups that were statistically significant in DFU improvement was a treatment group above 10 sessions with p-value = 0,001. Conclusion. The total session of HBOT as adjuvant therapy above 10 shows that it is the most significant improvement for DFU with a decrease in the ulcer degree and reduced wound size.
Advanced Directives in Palliative Care Shatri, Hamzah; Faisal, Edward; Putranto, Rudi; Sampurna, Budi
Jurnal Penyakit Dalam Indonesia Vol. 7, No. 2
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Initially palliative care is emphasized at the end of life, but the right thing is to begin identifying palliative care needs when the disease is diagnosed. Palliative care is the treatment needed to improve the quality of life of patients and their families that suffering from life threatening and progressive disease such as cancer, non-cancer diseases, and HIV/AIDS (human immunodeficiency virus/acquired immunodeficiency syndrome). Palliative care decision must be in place from the beginning of treatment, so the patient’s preferences are met. The goals of this care are to reduce physical, social, psychological, and spiritual suffers. Further treatment plan is based on discussion between patient, family, and health care worker. The final result is identification and decision that can be written in advanced directives.
Pengelolaan Predialisis Pasien Penyakit Ginjal Kronik Hustrini, Ni Made
Jurnal Penyakit Dalam Indonesia Vol. 7, No. 2
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Efficacy of Argon Plasma Coagulation Treatment in Radiation Colitis Patients and Its Confounding Factors Ariadno, Aru; Makmun, Dadang; Sulaiman, Andri S; Koesnoe, Sukamto
Jurnal Penyakit Dalam Indonesia Vol. 7, No. 2
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Introduction. Argon plasma coagulation (APC) is widely used in the treatment of radiation colitis among patients with gynecology, colorectal and urology malignancy. This study aimed to measure the result of APC conducted on radiation colitis patients and its counfounding factors. Methods. An analytic descriptive study with retrospective cohort design was conducted among radiation colitis patients received APC treatment in Cipto Mangunkusumo Hospital, Jakarta. Data were collected from medical record database between April 2012 until October 2019. Results. As much as 180 radiation colitis patients received APC treatment fulfilled inclusion criteria with characteristics female patients (89.4%) and age >50 years old (83.9%) were included in this study. Types of tumor were dominated by gynecology malignancy (88.9%). As much as 81.3% subjects had successful APC treatment. Median number of efficacy of APC treatment in this study was 2 sessions. All of the subjects had anemia before the first APC treatment. There was improvement in Hb level, median Hb before the first APC treatment was 8 g/dL (3-11 g/dL) and median Hb level before the last APC treatment was 12 g/dL (10-14 g/dL). As much as 59.2% subjects who had successful APC treatment were no longer had anemia after APC treatment, improvement of anemia status was 1.628 times more likely in subjects who had successful APC treatment compared to subjects who did not have successful APC treatment (p=0.017). Age, gender, malignancy types, hypertension, and diabetes mellitus were not the confounding factors to anemia status in successful APC treatment. Conclusion. There was improvement in anemia status on radiation colitis patients receiving APC treatment in RSUPN-CM.
Anti-DFS70 as Nonsystemic Autoimmune (Primary Billiar Cholangitis) Concomitant Disease Marker in Systemic Lupus Erythematosus Putra, Yasjudan Rastrama; Mulya, Deshinta Putri; Indrarti, Fahmi
Jurnal Penyakit Dalam Indonesia Vol. 7, No. 2
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Anti-dense fine speckled 70 (DFS70) is known as a non-systemic autoimmune marker. It is only found in 1% of systemic autoimmune patients and 2–22% in healthy population. To the best of our knowledge, no anti-DFS70 positive has been reported in systemic lupus erythematosus (SLE) patients with primary billiary cholangitis (PBC) comorbidities. We reported a 40-year-old woman that was diagnosed with SLE 1-month before, came to the hospital due to seven days of fatigue, loss of appetite, icteric, arthralgia, hair loss, and unexplained fever. Total bilirubin was 9.46 mg/dl, direct bilirubin 7.73 mg/dl, gamma-glutamyl transferase (GGT) 503 U/L, alkaline phosphatase (ALP) 520 U/L, ANA-IF 1:1000, ANA-profile measurement borderline on the anti-centromere B, and three positives on the DFS70. Magnetic resonance cholangiopancreatography (MRCP) shown the PBC feature. After ursodeoxycholic acid (UDCA) therapy 250 mg twice daily, ALP and GGT backed to normal limits within two months. This case reminds the doctor that anti-DFS70 finding in SLE needs further evaluation, whether other nonsystemic autoimmune exist or not. Concomitant PBC with SLE well responded with UDCA standard therapy.

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