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Journal of Pharmaceutical and Sciences.

jps
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Published by Universitas Tjut Nyak Dhien

ISSN : - EISSN : 26563088 DOI : https://doi.org/10.36490/journal-jps.com

Core Subject : Health, Science, Agriculture, Engineering,

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, Medicinal Chemistry, Molecular Pharmacology, Novel drug delivery system, Nanotechnology, Analytical Chemistry, Organic Chemistry, Natural Chemistry, Polymer Sciences, Clinical Pharmacy, pharmaceutical management, pharmacoeconomics, pharmacoepidemiology, clinical pharmacy, community pharmacy, social pharmacy, pharmaceutical marketing, government policies related to pharmacy, pharmaceutical care, Medical Biotechnology, Biochemistry, food chemistry, health and applied sciences relevant to the field of pharmacy. Journal of Pharmaceutical and Sciences (JPS) accepts manuscripts in Indonesian Language (Bahasa Indonesia) with titles and abstracts in bilingual, both Indonesian and English. We accept article manuscripts in the form of original research, literature reviews, and systematic reviews. We do not accept articles in the form of case reports

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)

Articles 68 Documents

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Search results for , issue "JPS Volume 6 Nomor 2 (2023)" : 68 Documents clear

Article Review : Studi Potensi Tanaman Herbal indonesia Indonesia Sebagai Antidiabetes pada Penderita Diabetes Tipe 2 Vriezka Mierza; Deborah Chennia Lau; Diara Ravika Hadjami; Tiara Cinta Amelia; Mochammad Galuh Ryandha
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Pendahuluan : Diabetes merupakan penyakit degeneratif yang meningkat setiap tahunnya di dunia. Beberapa tanaman herbal di Indonesia dapat digunakan sebagai terapi antidiabetes. Tujuan: mengidentifikasi bagian tanaman herbal Indonesia yang berpotensi memberikan efek antidiabetes dengan senyawa yang berperan di dalamnya dalam penelitian in vivo. Metode: Tinjauan artikel dengan pengumpulan data dari tahun 2013 hingga 2023 menggunakan database google scholar, pubmed, dan science direct yang difilter menurut kriteria inklusi dan eksklusi oleh PRISMA. Hasil: Didapatkan 16 jurnal mengenai penelitian in vivo tanaman herbal Indonesia yang diambil dari daun, bunga, buah, dan rimpang yang digunakan sebagai terapi antidiabetes. Senyawa metabolit seperti flavonoid, tanin, saponin,triterpenoid berperan dalam memberikan efek antidiabetes dengan cara menurunkan kadar glukosa darah dan memicu pengendapan insulin. Kesimpulan: Beberapa tumbuhan herbal Indonesia secara keseluruhan mengandung flavonoid yang berperan dalam menurunkan kadar glukosa darah. Bagian tumbuhan herbal Indonesia yang paling banyak digunakan dalam hasil review jurnal tersebut adalah daunnya

Pengayaan kandungan antioksidan daging ayam melalui marinasi dengan jus buah andaliman (Zanthoxylum acanthopodium) Kurniawan Sinaga; Nur
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Andaliman fruits are known for high antioxidants and antibacterial ingredients. This herb has a high potential to pretend oxidation and contamination of foodstuffs, such as meat. The research aims to investigate the effect of marination with andaliman fruit juice on chicken meat antioxidant activity and Salmonella availability. About 12 samples of duck meat were divided into 4 groups such as 0 % andaliman fruit juice (P0), andaliman fruit juice 10 % (P1), andaliman fruit juice 15 % (P2), and andaliman fruit juice 20 % (P3). Each group consisted of 3 samples. Antioxidant activity and Salmonella availability were examined in the research. The research showed that Antioxidant activity P0 was about 18,33 %, P1 (23,46 %), P2 (9,01 %), and P3 (13,35 %). Salmonella examination showed that P0 positive, P1 positive, P2 positive, and P3 negative. E. coli test showed that all treatments were negative. The research concluded that marination with 10 % andaliman fruit juice increases the antioxidant activity of chicken meat and marination with 20 % could erase Salmonella availability in chicken meat.

Hubungan Tingkat Pengetahuan dan Ketepatan Penggunaan Obat Simvasatatin Pada Pasien Hiperkolesterolemia di Rumah Sakit Advent Medan Andre Budi; Rike Monika Sijabat
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Hypercholesterolemia is a condition when there is a disturbance in the body which is characterized by an increase in blood cholesterol levels exceeding 240 mg/dl. Pharmacological therapy that can be used to lower cholesterol levels is statin class drugs. Simvastatin is a hypercholesterolemia drug that is often used as a first-line drug compared to other statin class drugs. Based on the research that has been done, the results of the correlation test were obtained with a value 0,553, which means that there is a strong correlation between the level of knowledge and the accuracy of using simvastatin.

Review Artikel : Potensi Berbagai Bahan Alam Sebagai Insektisida Alami Kutu Rambut (Pediculus humanus capitis) Rifani Shalsadila; Mega Nuryanti; Purwaeni Purwaeni
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

The head louse parasite (pediculus humanus capitis) is the cause of a common infection in tropical climates called pediculosis capitis. The food of head lice comes from the blood sucked on the human scalp. Various ways to deal with head lice are using lice combs and insect repellents (insecticides). Insecticidal liquid is a synthetic chemical containing permethrin, lindae, DDT malathion and carbaryl which can interfere with the human nervous system when used long-term. This study aimed to find various natural ingredients that have the potential as natural insecticides in overcoming pediculosis capitis. The method used was literature review through Google Scholar, ScienceDirect and ResearchGate websites. The results obtained are lime (Citrus hystrix), red betel (Piper ornatum), crimson (Annona squamosa), kirinyuh (Chromolaena adorate), pandan wangi (Pandanus amaryllifolius), bay leaves koja (Murraya koenigii L.), duku (Lansium domesticum corr), soursop (Annona muricata L.), eucalyptus (Melaleucalucalus L.), eucalyptus (Melaleuca cajuputi), garlic, shallots, coconut (Cocos nucifera), sembung rambat (Mikania micrantha), aloe vera (Aloe vera), jarak pagar (Jatropa curcas L.) and mengkudu (Morinda citrifolia) have the potential as natural insecticides in overcoming pediculosis capitis.

Analisis Kadar Kafein Biji Kopi Arabika Dengan Variasi Temperatur Sangrai Yang Tumbuh Di Aek Sabaon Tapanuli Selatan Mey Linda Hasibuan; Sumardi Sumardi; Nilsya Febrika Zebua; Nurmala Sari
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Roasting can change the physical properties and chemical properties of coffee beans such as the composition of the chemical compounds contained in them, namely caffeine compounds. Caffeine is one of the compounds contained in coffee beans. It is necessary to analyze the differences in the roasting profile in the roasting process of coffee beans to find out if there is a difference in caffeine levels in coffee based on variations in roasting temperature. This study was conducted to determine the caffeine content in arabica coffee grown in Aek Sabaon Village, Marancar District, South Tapanuli Regency with variations in roasting temperatures. The roasting method is carried out in a modern way using a coffee roasting device equipped with a thermometer. The extraction method used is liquid-liquid extraction using chloroform as the solvent. The determination of arabica coffee caffeine levels with variations in roasting temperatures was carried out using the UV-vis spectrophotometry method using HCl 0.1 N as solvent. The results showed caffeine content in arabica coffee samples with variations in roasting temperatures with temperatures of 180°C, 200°C and 210°C respectively; 11.23%, 11.30% and 13.92%. Statistically, the test using ANOVA showed a difference in caffeine levels in the variation in roasting temperature which was not very significant because the significance of p > 0.05 and in the t Test it met the requirements of the significance value p < 0.05 so that it showed a free variable positive and significant effect on the bound variable.

Nanotope™ sebagai Sistem penghantaran Cosmeceutical untuk Meningkatkan Intensitas Efek pada Kulit Ulma Sintia; Regina Andayani; Henny Lucida
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Nanotope™ as a monolayer nanoencapsulated vesicular delivery system, consisting of a membrane formed by phospholipids (lecithin) and cosurfactants. Nanotope™ is an Ultra-small Unilamellar Carrier (USUC) having an average globule size of 0-40 nm. The diameter of the globule size which is smaller than the size of the skin pores allows the active ingredients to penetrate the stratum corneum to reach the target. Natural active compounds such as catechin, alpha mangostin, quercetin, and ascorbic acid have great potential as active ingredients to be formulated in cosmetic preparations. However, these compounds have limited penetration into the skin. Therefore, the Nanotope™ delivery system is the best solution for encapsulating these active ingredients without reducing their effectiveness. Cosmetic serums, creams and emulgel are preparations that are most likely to be formulated with the Nanotope™ delivery system. This review article presents Nanotope™ preparation techniques along with their evaluations, as well as active compounds from natural ingredients that have the potential for cosmetic applications with the Nanotope™ delivery system.

Pengaruh Kerja Sama Antara Rumah Sakit dengan Badan Penyelenggara Jaminan Sosial (BPJS) Kesehatan Terhadap Jumlah Kunjungan Rumah Sakit di Indonesia Iha Nursolihah; Dian Agnesa Sembiring; Sekar Ayu Runggandini
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

According to BPJS Kesehatan data, the number of health facilities that cooperate with BPJS Kesehatan does not necessarily increase, even in 2019 the achievements of the FKRTL that work together have decreased, even though every year NHI participants have increased. BPJS Kesehatan continues to try to optimize the NHI’s system so that the benefits can be felt by participants and health facilities as providers, one of which is an increase in hospital visits. This study aims to determine the effect of cooperation with BPJS Kesehatan on the number of hospital visits in Indonesia. This type of research is analytic observational with a cross-sectional study design. The research samples were all hospitals in Indonesia that were designated as referral hospitals and other hospitals were sampled using a sample size calculation. The selected sample was 532 hospitals. The statistical test results obtained a value of p = 0.0001 for all independent variables so that there was a significant difference in the average number of emergency patients, number of inpatients, number of outpatient visits, and number of laboratory visits between hospitals cooperating with BPJS Kesehatan and hospitals that are not partners with BPJS Kesehatan. Thus, there is an influence between cooperation with BPJS Kesehatan on the number of hospital visits in Indonesia.

Review Article : Potensi Aktivitas Antioksidan Dari Berbagai Tanaman Untuk Tabir Surya Himyatul Hidayah; Mentari Mentari; Ainun Mar’atus Putri Warsito; Dinda Dinanti
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Sunscreen is a cosmetic preparation which is usually used as a treatment for the skin to prevent free radicals and protect the skin from the dangerous sunglight.. Many Activite compund in plants that have antioxidant activity are believed to be able to ward off both free radicals and exposure to sunlight. From the research of literature review, it aims to determine the relationship between potential antioxidant activity in plants for sunscreen cosmetic preparations. The method of research is searching the databases from various articles like Google Scholar, ResearchGate, PubMed. The results showed that the active substances from various plants have the potential as antioxidants that can be used as sunscreens to protect the skin from radicals and sunlight

Studi Kapabilitas Proses Tablet Thiamazole 100 mg pada Salah Satu Industri Farmasi di Jawa Barat Kaila Keyshia Mei; Holis Abdul Holik
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

The quality of a product needs to be maintained throughout its life cycle so that the quality remains consistent to the consumers. Therefore, regular quality control is needed to maintain quality according to predetermined specifications. To be able to maintain product quality, quality control is carried out using the Six Sigma method with DMAIC stages (Define, Measure, Analyze, Improve, Control). The purpose of this study was to determine the reproducibility of 10 mg Thiamazole tablet product which can be considered in determining the bypass status of the product at certain stages of testing, to determine the capability of the production process, and to analyze Thiamazole tablets. The results showed that the specification requirements and control limit range requirements. At the printing and coating stages the assay has Cpk value > 1, so that it can be considered the application of bypass status, but at the mixing and coating stages the dissolution has Cpk value < 1 which indicates that the process does not yet have a good value trend. This can be caused by several factors, for example personnel factors, machines, materials and methods at the stage of analysis of content and production.

Faktor-Faktor Resiko Terjadinya Stroke Pada Pasien Hipertensi Di Puskesmas Glugur Kota Medan Nurul Rahmah Siregar; Helmiwati Helmiwati
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Stroke is one of the major problems faced throughout the world, both in developed and developing countries. An acute attack of stroke causes physical and mental disability as well as a sudden high death rate, both in productive and old age. Hypertension is a condition where a person experiences an increase in blood pressure above normal (> 140/90 mmHg) which results in mortality and mortality. This study aims to determine the risk factors for stroke in hypertensive patients at the Glugur Health Center, Medan. The case population of the study was 150 stroke sufferers, the researchers took a sample of 20%, the results of the study showed that there were 13 (43%) healthy respondents and 17 (56%) unhealthy respondents. Thus it is expected to further improve health education to patients about the benefits of a regular lifestyle or diet and exercise as needed, because an unhealthy lifestyle can cause various diseases.

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Fakultas Farmasi Universitas Tjut Nyak Dhien Jl. Gatot Subroto Gg. Rasmi No. 28, Sei Sikambing C. II, Medan Helvetia, Kota Medan, Sumatera Utara 20123

Location
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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Salman

Contact Email salman.kimia@gmail.com

Phone +6285277011177

Journal Mail Official admin@journal-jps.com

Editorial Address Fakultas Farmasi Universitas Tjut Nyak Dhien Jl. Gatot Subroto Gg. Rasmi No. 28, Sei Sikambing C. II, Medan Helvetia, Kota Medan, Sumatera Utara 20123

Location Kota medan, Sumatera utara INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Salman

Contact Email
salman.kimia@gmail.com

Phone
+6285277011177

Journal Mail Official
admin@journal-jps.com

Editorial Address
Fakultas Farmasi Universitas Tjut Nyak Dhien Jl. Gatot Subroto Gg. Rasmi No. 28, Sei Sikambing C. II, Medan Helvetia, Kota Medan, Sumatera Utara 20123

Location
Kota medan,

Sumatera utara

INDONESIA