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Journal of Health Management and Pharmacy Exploration (JOHMPE)
Published by shm publisher
ISSN : 29854814     EISSN : 29855543     DOI : https://doi.org/10.52465/johmpe
Core Subject : Health,
Health Professions Medicine & Pharmacology Nursing Public Health Veterinary
Journal of Health Management and Pharmacy Exploration (JOHMPE) P-ISSN: 2985-4814 | e-ISSN: 2985-5543 is a journal that contains research material related to health management and pharmacy. Articles devoted to discussing any and all aspects of the most recent and noteworthy advancements in the fields of the development of health management science and pharmacy is possible to get the benefits of the application in life, especially from the perspective of the community, educational, and health institutions. The JOHMPE accepts manuscripts that are closely related to the health sector, including research articles, systematic reviews, and meta analyses. The Journal of Health Management and Pharmacy Exploration (JOHMPE) publishes contributions from a wide range of disciplines including: Health Policy Health Management Health Economics Health policy analysis Health policy ethics Politics of health Epidemiology Public health Phytochemistry social public policy Philosophy of health Clinical Pharmacy Community Pharmacy Pharmaceutics Pharmaceutical Chemistry Pharmacognosy
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 2 Documents
 1 
Search results for , issue "Vol. 4 No. 1 (2026): February 2026" : 2 Documents clear
Effectiveness of Extract and Fraction of Robusta Coffee Beans (Coffea Canephora) Against Streptozotosin-Nicotinamide Induced Blood Glucose Levels of Male White Mice Oklyan, Risny; Wijayanti, Tri; Widodo, Gunawan Pamudji
Journal of Health Management and Pharmacy Exploration Vol. 4 No. 1 (2026): February 2026
Publisher : Surya Hijau Manfaat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52465/johmpe.v4i1.640

Abstract

Robusta coffee bean have compounds flavonoids, alkaloids, saponins and tannins. This compound has the benefit of being an antihyperglycemic which plays a role in inhibiting absorption glucose, preventing the formation of AGEs chains, and increasing the activity of antioxidant enzymes. This research aims to determine the effectiveness of the robusta coffee bean fraction which is effective in reducing blood glucose levels in STZ-NA induced mice. Research conducted is experimental research. Using 30 mice aged 2-3 months with a body weight of 18-25 g and grouped into 6 groups, that is group I negative streptozotocin 5.6 mg/kg weight and nicotinamide 15.4 mg/kg weight, group II positive control was given glibenclamide 0.65 mg/kg weight, Group III was given robusta coffee bean extract 400 mg/kg weight Group IV was given the n-hexane fraction of 42 mg/kg weight, group V was given the ethyl acetate fraction of 38 mg/kg weight, group VI was given the water fraction of 216 mg/kg weight. The data has been analyzed and after 21 days of observation it was found that the ethyl acetate fraction and robusta coffee bean extract decreased blood glucose levels the same as the decrease in blood glucose levels in the positive group test.
Standardization of ethanol extracts from pomegranate fruit peels (Punica Granatum L.) using the reflux method Wulandari; Ardiantika, Nuri
Journal of Health Management and Pharmacy Exploration Vol. 4 No. 1 (2026): February 2026
Publisher : Surya Hijau Manfaat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52465/johmpe.v4i1.655

Abstract

Pomegranate peel (Punica granatum L.) is known to contain various active secondary metabolite compounds that have potential in the field of pharmacy. To ensure the quality, safety, and consistency of extracts as raw materials for traditional medicines, a standardization process is required that includes specific and nonspecific parameters. This study aims to standardize pomegranate peel extract and identify the active compounds it contains. Extraction was performed using the reflux method with 96% ethanol solvent. The specific parameters tested included organoleptic properties, water-soluble and ethanol-soluble extract levels, and identification of active compounds through phytochemical testing. The results showed that pomegranate peel extract met the quality standards for extracts with good specific and non-specific characteristics. The extract yield was 12.76%. The results of testing the non-specific parameters of water content, drying loss, ash content, and acid-insoluble ash content were 3.12%, 1.24%, 0.33%, and 0.19%, respectively. Specific standardization includes water-soluble extract content of 3.2% and ethanol-soluble extract content of 4.4%. Phytochemical testing of the extract showed the presence of active compounds such as alkaloids, flavonoids, saponins, tannins, quinones, and steroids.

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