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Al Makki Health Informatics Journal
Published by Al-Makki Publisher
ISSN : 30256518     EISSN : 30250501     DOI : -
Core Subject : Health,
Dentistry Health Professions Nursing Public Health Veterinary
l Makki Health Informatics Journal is an open-access scientific peer-review journal publishing. The Al Makki Health Informatics Journal focuses on exchanging information relating to intelligent computing and health informatics applied in industry, hospitals, government, and universities. All articles should include a validation of the idea presented, e.g. through case studies, experiments, or systematic comparisons with other approaches already in practice. Two types of papers are accepted: (1) A short paper that discusses a single contribution to a specific new trend or a new idea, and; (2) A long paper that provides a survey of a specific research trend using a systematic literature review (SLR) method, as well as a traditional review method. Topics of interest include, but are not limited to: Electronic health record E-Health Information Medical Image Processing & Techniques Data Mining in Healthcare Bioinformatics & Biostatistics Mobile applications for patient care Medical Image Processing & Techniques Hospital information systems Document handling systems Electronic medical record systems Standardization, and systems integration ICT in health promotion programmes e-health Guidelines and protocols E-learning & education in healthcare Telemedicine Software- Portals-Devices & Telehealth Public health & consumer informatics Data Mining & Knowledge Discovery in Medicine ICT for Patient empowerment ICT for Patient safety Medical Databanks-Databases & Knowledge Bases Healthcare Quality assurance Nursing Informatics Evaluation & Technology Assessment Home-based eHealth Health Management Issues Health Research Health Economics Issues Statistical Method for Computer Medical Decision Support Systems Medical Informatics or medicine in general Organizational, economic, social, clinical impact, ethical and cost-benefit aspects of IT applications in health care.
Arjuna Subject : Profesi Kesehatan - Terminologi Medis
Articles 10 Documents
 1 
Search results for , issue "Vol. 3 No. 3 (2025): Al Makki Health Informatics Journal" : 10 Documents clear
A Pharmacogenomic Study to Predict Reverse Remodeling Afies, Mohammad
Al Makki Health Informatics Journal Vol. 3 No. 3 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i3.51

Abstract

Cardiac remodeling refers to structural, functional, and molecular changes in the heart in response to stress or injury. These alterations, involving both cellular and interstitial changes, contribute to the progression of heart disease. Long-term activation of the autonomic nervous system (ANS) exacerbates these changes, leading to systemic vasoconstriction, sodium and water retention, and ventricular remodeling, which accelerates disease progression. Neurohormonal activation is essential in compensating for falling cardiac output in heart failure (HF), but it also plays a major role in the progression of the disease. This study explores the role of the renin-angiotensin-aldosterone system (RAA) and the sympathetic nervous system in cardiac remodeling, particularly in heart failure, and the influence of genetic factors on drug response. The research focuses on the ß2-Adrenergic Gln/Gln Receptor genotype, a key genetic variant relevant to pharmacogenomics in left ventricular hypertrophy (LVH) treatment. Using a comprehensive review of clinical and experimental data, this study highlights how genetic polymorphisms affect the pharmacokinetics and pharmacodynamics of drugs such as beta-blockers, ACE inhibitors, and ARBs. The findings indicate that while the ß2-Adrenergic Gln/Gln Receptor genotype significantly influences drug efficacy, the challenges in applying personalized treatments based on genetic data require significant time and cost investments. The study's implications emphasize the need for personalized therapies and enhanced pharmacogenomic research to improve treatment outcomes in heart failure management, particularly in drug response and disease progression.
The Effect of The Application of Head Coaching on The Work Motivation and Job Satisfaction of The Implementing Nurse at The Bandar Lampung Advent Hospital Gulo, Magdalena; Hastono, Sutanto Priyo; Wijayanti, Catharina Dwiana
Al Makki Health Informatics Journal Vol. 3 No. 3 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i3.52

Abstract

Nursing human resources today are experiencing a change in the generation of workers. The need for the role of the head nurse in carrying out coaching to support, collaborate, and facilitate nursing human resources of different generations in order to build effective working relationships, increase motivation, self-potential, and staff job satisfaction. The purpose of the study was to assess the impact of coaching training on nurses' motivation and job satisfaction. Quasi-experimental research design with one group pre-posttest design. Respondents in the research were implementing nurses, using questionnaire measuring tools. The results were obtained by the majority of respondents aged 20-30 years (42.9%), PK 2 career path (37.5%), nurse education (50.0%), and length of work 1-5 years (44.6%). Before the coaching training, the average motivation was 25.13 and job satisfaction was 23.73, while after the coaching training, the average motivation increased to 43 and job satisfaction increased to 35.98. The Paired Samples Test showed a significant effect of coaching training on motivation and job satisfaction with a p-value of 0.000, as well as an R square result of 0.838.  The need for the implementation of coaching by the head of the room to increase the motivation and work of nurses which will have an impact on the quality and effectiveness of nursing services.
Hyperosmolar Hyperglycemic State (HHS) and Diabetic Kidney Disease (DKD) as Acute and Chronic Complications of Type 2 Diabetes Mellitus in End-Stage Chronic Kidney Disease (CKD): a Case Report Premaiswari Suparthika, Ni Putu Radha; Sutarka , Nyoman
Al Makki Health Informatics Journal Vol. 3 No. 3 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i3.54

Abstract

Introduction: Hyperosmolar hyperglycemic state (HHS) is a life-threatening condition that often occurs in patients with type 1 and 2 diabetes mellitus characterized by hyperglycemic crises, hyperosmolarity, dehydration, with mild ketosis or no eketosis. Another chronic complication of Diabetes Mellitus is Diabetic Kidney Disease (DKD). Ni Putu Radha Premaiswari Suparthika1, I Nyoman Sutarka. Case Presentation: A 61-year-old male patient was referred with decreased consciousness since 5 days of SMRS. The patient has a history of type 2 diabetes mellitus since 20 years. In patients, signs were obtained in the form of decreased consciousness, severe hyperglycemia of 680 mg/dL, hyperosmolarity of 360 mOsm/kg, increase in anion gap >12, UTI complications as the trigger of HHS. In patients, moderate anemia was also found normochromic-normocyter, massive proteinuria, and decreased kidney function. Conclusion: In the 61-year-old male patient described in this case report, there are acute and chronic complications of Diabetes Mellitus that occur simultaneously and have caused high morbidity and mortality in patients.
The Relationship Between Stress And Adolescent Academic Perception Ability Based On Gender And Body Mass Index Alfiandari, A. Dhini; Ichsan, Rayhani; Aminuddin, Nurul Mutiah; Damry , Nurul Muf’idah
Al Makki Health Informatics Journal Vol. 3 No. 3 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i3.55

Abstract

Stress in adolescents has the potential to impact various aspects of physical and mental health, including perceived academic ability. Differences in gender and nutritional status such as body mass index (BMI) can affect stress levels and academic perception abilities in adolescents. Objective: To assess the relationship between stress and academic perception abilities based on gender and BMI in high school-aged adolescents. Methods: An observational analytical study with a cross-sectional approach was conducted on 53 students aged ≤18 years at SMAN 2 Parepare. Data were collected through an online questionnaire using the Indonesian version of the PSS-10 instrument and the TASES scale. BMI was calculated from weight and height. Data were analyzed using the t-test, ANOVA, and Pearson correlation. Results: There were no significant differences in stress scores or academic perception abilities based on gender and BMI category (p>0.05). There was no significant relationship between stress and academic perception abilities (r=–0.02; p=0.901). Conclusion: Gender and BMI status do not significantly influence stress and academic perception abilities. Other factors such as coping strategies and social support need further investigation.
Bioinformatics in Genomic Analysis: Opportunities and Challenges of Leveraging Big Data for Personalized Medicine Sidik, Dikdik Abdulah
Al Makki Health Informatics Journal Vol. 3 No. 3 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i3.67

Abstract

Advances in bioinformatics and genomics technology have created great opportunities in realizing personalized medicine. This study aims to analyze the role of bioinformatics in the use of genomic big data, emphasizing the opportunities, challenges, and integration strategies needed. The research method used is qualitative with an exploratory approach. Data were collected through in-depth interviews, focus group discussions, and documentation studies, then analyzed using thematic analysis techniques. The results of the study show that bioinformatics offers a variety of opportunities, such as the utilization of pharmacogenomics for drug response prediction, disease biomarker identification, multi-omics data integration, machine learning algorithm development, and early detection of genetic diseases. However, a number of challenges still hinder implementation, including genomic data privacy and security issues, limited computing infrastructure, lack of interdisciplinary human resources, lack of standardization of data formats, and regulatory and policy barriers. This research also emphasizes the importance of the strategy of integrating bioinformatics and big data through strengthening technological infrastructure, global data standardization, the use of artificial intelligence, privacy protection based on adaptive regulations, international collaboration, and the development of interdisciplinary education. The implications of this research not only enrich the academic literature, but also provide a practical basis for the formulation of more precise and equitable health policies. Thus, this study confirms that the use of bioinformatics is a strategic path towards the transformation of data-based health services, which is oriented to individual needs while maintaining the ethics and sustainability of the health system.
A Pharmacogenomic Study to Predict Reverse Remodeling Afies, Mohammad
Al Makki Health Informatics Journal Vol. 3 No. 3 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i3.51

Abstract

Cardiac remodeling refers to structural, functional, and molecular changes in the heart in response to stress or injury. These alterations, involving both cellular and interstitial changes, contribute to the progression of heart disease. Long-term activation of the autonomic nervous system (ANS) exacerbates these changes, leading to systemic vasoconstriction, sodium and water retention, and ventricular remodeling, which accelerates disease progression. Neurohormonal activation is essential in compensating for falling cardiac output in heart failure (HF), but it also plays a major role in the progression of the disease. This study explores the role of the renin-angiotensin-aldosterone system (RAA) and the sympathetic nervous system in cardiac remodeling, particularly in heart failure, and the influence of genetic factors on drug response. The research focuses on the ß2-Adrenergic Gln/Gln Receptor genotype, a key genetic variant relevant to pharmacogenomics in left ventricular hypertrophy (LVH) treatment. Using a comprehensive review of clinical and experimental data, this study highlights how genetic polymorphisms affect the pharmacokinetics and pharmacodynamics of drugs such as beta-blockers, ACE inhibitors, and ARBs. The findings indicate that while the ß2-Adrenergic Gln/Gln Receptor genotype significantly influences drug efficacy, the challenges in applying personalized treatments based on genetic data require significant time and cost investments. The study's implications emphasize the need for personalized therapies and enhanced pharmacogenomic research to improve treatment outcomes in heart failure management, particularly in drug response and disease progression.
The Effect of The Application of Head Coaching on The Work Motivation and Job Satisfaction of The Implementing Nurse at The Bandar Lampung Advent Hospital Gulo, Magdalena; Hastono, Sutanto Priyo; Wijayanti, Catharina Dwiana
Al Makki Health Informatics Journal Vol. 3 No. 3 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i3.52

Abstract

Nursing human resources today are experiencing a change in the generation of workers. The need for the role of the head nurse in carrying out coaching to support, collaborate, and facilitate nursing human resources of different generations in order to build effective working relationships, increase motivation, self-potential, and staff job satisfaction. The purpose of the study was to assess the impact of coaching training on nurses' motivation and job satisfaction. Quasi-experimental research design with one group pre-posttest design. Respondents in the research were implementing nurses, using questionnaire measuring tools. The results were obtained by the majority of respondents aged 20-30 years (42.9%), PK 2 career path (37.5%), nurse education (50.0%), and length of work 1-5 years (44.6%). Before the coaching training, the average motivation was 25.13 and job satisfaction was 23.73, while after the coaching training, the average motivation increased to 43 and job satisfaction increased to 35.98. The Paired Samples Test showed a significant effect of coaching training on motivation and job satisfaction with a p-value of 0.000, as well as an R square result of 0.838.  The need for the implementation of coaching by the head of the room to increase the motivation and work of nurses which will have an impact on the quality and effectiveness of nursing services.
Hyperosmolar Hyperglycemic State (HHS) and Diabetic Kidney Disease (DKD) as Acute and Chronic Complications of Type 2 Diabetes Mellitus in End-Stage Chronic Kidney Disease (CKD): a Case Report Premaiswari Suparthika, Ni Putu Radha; Sutarka , Nyoman
Al Makki Health Informatics Journal Vol. 3 No. 3 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i3.54

Abstract

Introduction: Hyperosmolar hyperglycemic state (HHS) is a life-threatening condition that often occurs in patients with type 1 and 2 diabetes mellitus characterized by hyperglycemic crises, hyperosmolarity, dehydration, with mild ketosis or no eketosis. Another chronic complication of Diabetes Mellitus is Diabetic Kidney Disease (DKD). Ni Putu Radha Premaiswari Suparthika1, I Nyoman Sutarka. Case Presentation: A 61-year-old male patient was referred with decreased consciousness since 5 days of SMRS. The patient has a history of type 2 diabetes mellitus since 20 years. In patients, signs were obtained in the form of decreased consciousness, severe hyperglycemia of 680 mg/dL, hyperosmolarity of 360 mOsm/kg, increase in anion gap >12, UTI complications as the trigger of HHS. In patients, moderate anemia was also found normochromic-normocyter, massive proteinuria, and decreased kidney function. Conclusion: In the 61-year-old male patient described in this case report, there are acute and chronic complications of Diabetes Mellitus that occur simultaneously and have caused high morbidity and mortality in patients.
The Relationship Between Stress And Adolescent Academic Perception Ability Based On Gender And Body Mass Index Alfiandari, A. Dhini; Ichsan, Rayhani; Aminuddin, Nurul Mutiah; Damry , Nurul Muf’idah
Al Makki Health Informatics Journal Vol. 3 No. 3 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i3.55

Abstract

Stress in adolescents has the potential to impact various aspects of physical and mental health, including perceived academic ability. Differences in gender and nutritional status such as body mass index (BMI) can affect stress levels and academic perception abilities in adolescents. Objective: To assess the relationship between stress and academic perception abilities based on gender and BMI in high school-aged adolescents. Methods: An observational analytical study with a cross-sectional approach was conducted on 53 students aged ≤18 years at SMAN 2 Parepare. Data were collected through an online questionnaire using the Indonesian version of the PSS-10 instrument and the TASES scale. BMI was calculated from weight and height. Data were analyzed using the t-test, ANOVA, and Pearson correlation. Results: There were no significant differences in stress scores or academic perception abilities based on gender and BMI category (p>0.05). There was no significant relationship between stress and academic perception abilities (r=–0.02; p=0.901). Conclusion: Gender and BMI status do not significantly influence stress and academic perception abilities. Other factors such as coping strategies and social support need further investigation.
Bioinformatics in Genomic Analysis: Opportunities and Challenges of Leveraging Big Data for Personalized Medicine Sidik, Dikdik Abdulah
Al Makki Health Informatics Journal Vol. 3 No. 3 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i3.67

Abstract

Advances in bioinformatics and genomics technology have created great opportunities in realizing personalized medicine. This study aims to analyze the role of bioinformatics in the use of genomic big data, emphasizing the opportunities, challenges, and integration strategies needed. The research method used is qualitative with an exploratory approach. Data were collected through in-depth interviews, focus group discussions, and documentation studies, then analyzed using thematic analysis techniques. The results of the study show that bioinformatics offers a variety of opportunities, such as the utilization of pharmacogenomics for drug response prediction, disease biomarker identification, multi-omics data integration, machine learning algorithm development, and early detection of genetic diseases. However, a number of challenges still hinder implementation, including genomic data privacy and security issues, limited computing infrastructure, lack of interdisciplinary human resources, lack of standardization of data formats, and regulatory and policy barriers. This research also emphasizes the importance of the strategy of integrating bioinformatics and big data through strengthening technological infrastructure, global data standardization, the use of artificial intelligence, privacy protection based on adaptive regulations, international collaboration, and the development of interdisciplinary education. The implications of this research not only enrich the academic literature, but also provide a practical basis for the formulation of more precise and equitable health policies. Thus, this study confirms that the use of bioinformatics is a strategic path towards the transformation of data-based health services, which is oriented to individual needs while maintaining the ethics and sustainability of the health system.

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