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Mochamad Nashrullah
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Published by Antis Publisher
ISSN : -     EISSN : 30321085     DOI : https://doi.org/10.61796/jmgcb.v1i1
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology
The European Journal of Medical Genetics and Clinical Biology is a peer-reviewed journal that publishes articles in English on various aspects of human and medical genetics, the genetics of experimental models, and developmental anomalies. Original clinical and experimental research articles, short clinical reports and review articles are welcome on topics such as: Clinical genetics and genomics, including neurodevelopmental disorders and single or multiple malformations syndromes and dysmorphology; Inherited predisposition to cancer: rare inherited cancer predisposition syndromes and biology and pathophysiology of inherited cancers; Fetal medicine and prenatal diagnosis, including prenatal diagnosis, prenatal screening, fetal therapies and teratology; Diagnostic methods including sequencing studies (gene level), transcriptome studies, methylome and other Omics technologies, variant interpretation and functional validation; Bioinformatics and statistical methods in genetics; Personalized Medicine and therapies, including gene therapy and gene editing, non-genetic treatment of genetic disease, pharmacogenetics and genomics, theranostics and clinical trials; Molecular biology and pathophysiology of genetic and genomic diseases: biology of cell, pathways and systems, epigenetics and gene regulation, biology and pathophysiology of specific genes and non-coding DNA; Genetics and variants in populations: carrier screening, population genetics, evolutionary genetics, genetic epidemiology of diseases, genome variation and architecture in normal population;
Arjuna Subject : Biokimia, Genetika dan Biologi Molekuler - Biokimia, Genetika dan Biologi Molekuler (Lain-Lain)
Articles 223 Documents
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EVALUATING THE OUTCOMES OF POSTPARTUM INFECTIOUS COMPLICATIONS IN IRAQI WOMEN Wasan Faisal Rashid Al-Azzawi; Fadia Mijbil Abbas; Hend Raheem Abdelhamze Alkharkushi
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 6 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i6.607

Abstract

Background: In the United States, there is not enough new data about how many infections after birth happen or how likely certain problems will be if they occur. In Germany, some research shows that about 10% of women who die while giving birth are killed by blood poisoning. Objective: This study is interested to determine clinical findings of postpartum infectious complications related to Iraqi women. Patients and methods: 88 women enrolled in different hospitals in Iraq for delivery or postpartum care and they were screened for their vital signs during this period. Any woman with a fever (> 38.0 °C) or body temperature (
MODERN VIEW TO OPTIMIZATION OF DIAGNOSTICS OF PARKINSON'S DISEASE Daminova Hilola Maratovna
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 6 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i6.617

Abstract

Parkinsonism is one of the most significant problems of clinical neurology, both due to its high prevalence in the world's populations and due to the significant disability of patients. The work analyzes the diagnosis of Parkinson's disease (as well as other neurodegenerative diseases) at the prodromal stage. A review of methods for preclinical and early clinical diagnosis of PD shows that the study of prodromal markers and criteria for the premotor phase of PD will make it possible in the future to significantly change the course of the disease using neuroprotective therapy at the stage preceding the death of a significant number of dopaminergic neurons of the substantia nigra.
THE ROLE OF SENSITIVITY LEVELS IN THE PATHOGENESIS OF ALLERGIC RHINITIS AND BRONCHIAL ASTHMA OF THE GROUP UNDER STUDY Ikramova Shakhnoza Abdurasulovna
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 6 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i6.627

Abstract

This article will provide feedback and feedback on the role of sensitivity levels in the pathogenesis of allergic rhinitis and bronchial asthma of the group under study. Allergic rhinitis and bronchial asthma are prevalent chronic inflammatory diseases that significantly impact the quality of life of millions of individuals worldwide. Both conditions are characterized by heightened immune responses to allergens, leading to inflammation of the respiratory tract. Recent research has shed light on the crucial role of Group 2 Innate Lymphoid Cells (ILC2s) in the pathogenesis of these diseases. Understanding the mechanisms by which ILC2s contribute to allergic rhinitis and bronchial asthma offers potential for novel therapeutic interventions
EVALUATE THE EFFECT OF SALVIA OFFICINALIS AND CARDAMOM ON ANIMAL PRODUCTIVITY OF BROILER CHICKENS Sawsan Abdul Faraj Mohammed; Ruya Fareed Jasim
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 6 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i6.642

Abstract

It is in considerable demand to produce poultry meat and eggs of superior quality at affordable costs without using growth promoters or antibiotics, so the current study aimed to evaluate the effect of Salvia officinalis and Cardamom on animal productivity of broiler chickens. This experiment was carried out at the poultry field of the Agricultural Experiment Station, College of Agriculture, Tikrit University. Ninety unsexed, one-day-old Ross 308 broiler chicks were employed. The results showed that the hemoglobin concentration, RBC counts and PCV of S. officinalis boilers and cardamom boilers indicated a significant (P≤0.05) elevated compared to the standard diet boilers. While, WBC count of S. officinalis boilers and cardamom boilers indicated non-significant (P≤0.05) elevated compared to the standard diet boilers. For antioxidant enzymes, the glutathione and catalase levels of S. officinalis boilers and cardamom boilers indicated a significant (P≤0.05) elevated compared to the standard diet boilers. Finally, total protein and albumin activities of S. officinalis boilers and cardamom boilers indicated a significant (P≤0.05) reduced compared to the standard diet boilers. It is concluded from the current study that both S. offcinalis and cardamom showed a stimulating effect on blood parameters and raising protein levels. S. offcinalis and cardamom can be considered an enhancer of the performance of broiler chickens.
DEFICIENCY OF VITAMIN D IN PATIENT WITH PRIMARY HYPOTHYROIDISM AND AS RELATED RISK FACTOR FOR CARDIOVASCULAR DISEASES Sura Sudad Sami; Fatima Ayad Nemeh; Maryam Ghassan Fakhry; Hala Thaer Kamal
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 6 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i6.643

Abstract

Hypothyroidism is believed to be associated with dyslipidemia and is considered a risk factor for the development of atherosclerotic cardiovascular diseases (ASCVD). Vitamin D, due to its steroid hormone action, retains cell function and controls the metabolism of lipids. Therefore, the present study was carried out to show the association of the risk factors of ASCVD. Cardiovascular disease (CVD) is caused by both clinical and subclinical hypothyroidism by disrupting healthy endothelial function by various mechanisms such as inflam- mation, triggering lipid disorders and oxidative stress. In the present study, a strong correlation was observed between increasing TSH and the parameters of lipid profile Hypothyroidism and hypovitaminosis D are known as inde-pendent risk factors for the development of cardiovascular diseases. Hypothyroidism and hypovitaminosis D are associated and correlated with total cholesterol, triglycerides, and low-density lipoprotein in Saudi patients. It is also recom- mended that vitamin D deficiency be checked in hypothyroid patients and that appropriate supplementation may be given if needed. Furthermore, for early detection and/or prediction of cardiovascular disease, screening of thyroid hormone and vitamin D levels should be undertaken at an early stage.
PREVALENCE OF BACTERIAL VAGINITIS AMONG WOMEN USING DIFFERENT TYPES OF IUDS Marwa Najat Ahmed; Asal Aziz Tawfeeq; Khalidah Mohammed Amin
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 6 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i6.655

Abstract

Background: A coil, also known as an intrauterine contraceptive device (IUCD or ICD), is a small birth control method that is put into the uterus to stop pregnancy. It usually starts in the endocervix and vagina and spreads up the body, causing endometritis, salpingitis, tubo-ovarian abscesses, parametritis, oophoritis, and/or pelvic peritonitis. objective: The objective of the current study was to investigate the prevalence of bacteria causing vaginitis among women using different types of intra uterine devices Materials and methods: The study was conducted in Kirkuk city from November 1, 2023, to April 30, 2024, using high vaginal swabs from 186 fertile women using intrauterine devices (IUDs). Demographic, medical, and gynecologic histories were recorded, and all patients underwent pelvic examinations. Swabs from the posterior fornix of the vagina were taken for microbiological analysis. The study included women aged 18-45 using IUDs, and excluded those who had received antibiotics, had preexisting systemic or infectious diseases, or experienced bleeding. Ethical approval was obtained, and informed consent was signed by all participants. The swabs were cultured on blood agar , MacConkey agar, Mannitol salt agar and deman rosa sharpe agar and Eosin methylene blue agar and incubated at 37°C for 24 hours. The colonies were picked, purified, and identified through a series of biochemical tests, including Gram staining, motility tests, and enzyme and fermentation tests. The Vitek 2 system was used for microbial identification and susceptibility testing. Results: In a study of 148 women using copper IUDs, 66 (44.59%) tested positive for vaginal swab cultures, while 82 (55.41%) tested negative. Similarly, among 38 women using hormonal IUDs, 17 (44.74%) had positive culture results, and 21 (55.26%) tested negative. Overall, out of 186 women tested, 83 (44.62%) had positive cultures. Among the 83 positive cases, 66 (79.52%) were in copper IUD users, and 17 (20.48%) were in hormonal IUD users. Escherichia coli was the most common bacterium, found in 40.91% of positive cultures, followed by Staphylococcus epidermidis (13.64%), and other bacteria including Staphylococcus aureus, Actinomyces israelii, and Proteus mirabilis, each at 9.09%. In women with positive cultures using copper IUDs, E. coli was most prevalent (47.06%), followed by Staphylococcus aureus and Staphylococcus epidermidis (17.65% each). Among women with positive cultures, 13.25% had diabetes, compared to 4.85% with negative cultures. Hypertension was present in 3.61% of women with positive cultures versus 1.94% with negative cultures. Duration of IUD use also showed a significant correlation with culture results. Women with positive cultures using copper IUDs had the highest percentage in the 1-2 year duration category (43.94%), while those using hormonal IUDs had the highest in the same category (47.06%). Antibiotic sensitivity testing revealed that Imipenem, Meropenem, Tigecycline, and Colistin were 100% effective against E. coli isolates from women using IUDs. However, high resistance rates were observed for Ampicillin/Sulbactam (71.79%) and Ciprofloxacin (84.62%). Ceftolozane/Tazobactam and Gentamicin had relatively high sensitivity rates, while Ceftazidime/Avibactam showed moderate sensitivity. Conclusions The study reveals a significant proportion of women with copper and hormonal IUDs tested positive for vaginal infections, with Escherichia coli being the predominant bacterium isolated,significant differences were noted in the clinical presentation and comorbidities of women with positive cultures compared to those with negative cultures.study identified antibiotics with high sensitivity rates against E. coli isolates, such as Imipenem, Meropenem, Tigecycline, and Colistin, highlighting potential treatment options for IUD-associated infections caused by multidrug-resistant strains. Conversely, antibiotics like Ampicillin/Sulbactam and Ciprofloxacin demonstrated high resistance rates
ASSESSMENT OF THE KNOWLEDGE AND ATTITUDE TOWARDS CIGARETTE SMOKING AMONG YOUTHS IN OGBIA TOWN; OGBIA LOCAL GOVERNMENT AREA OF BAYELSA STATE Obuzor, Mezewo Emerinwe (Ph.D); Emeodu, Elijah Nwabueze (Ph.D); Ariwera Dokubo
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 6 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i6.661

Abstract

This study investigated the assessment of the knowledge and attitude towards cigarette smoking among youths in Ogbia Town; Ogbia Local Government Area of Bayelsa State. The population of the study consisted of three hundred (300) Youths, and one hundred and fifty 150 (50%) were selected as the sample size for the study. The simple random sampling technique and systematic sampling techniques were adopted to select the sample for the study. Three research questions and objectives were used. The instrument used for data collection was a well-structured questionnaire; simple percentage was used to answer the research questions. The results showed that; 95.3% of the respondents knew the negative effect of cigarettes on health; 96.7% of the respondents said smoking should be strictly prohibited in public areas. 96.0% of the respondents indicated that Smoking is a disgusting behavior; 90.0% of the respondents indicated that smoking is hazardous to the health of others, while 19.3% of the respondents did not accept that smoking is a personal freedom. Again, 84.0% of the respondents indicated that peer groups influenced the cigarette smoking habits among youths. In light of the findings of the study, it was therefore recommended that; policies prohibiting the advertisement and use of tobacco in public places be properly enforced by the government, parents, and educational management; and finally that religious leaders should be good role models that will help youths in quitting cigarettes smoking
BIRTH PHOTOGRAPHY AS A NORMAL MATERNITY FACILITY AT PMB Desi Latifatul Hasanah; Yanik Purwanti
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 6 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i6.662

Abstract

Birth photography is a new form of birth art, the emergence of birth photography as an expression of a woman's birth experience that is centered on women. Photos become a means of imaginative adventure for human experience, communication between humans and themselves, between people and even between generations. This birth memoir is a form of celebration and gift for future children, parents, or anyone else for the moment of childbirth which only happens once in a woman's life even if there are subsequent births. With current technological advances, birth documentation as a medium for capturing beautiful memories of childbirth can be easily done, using a camera or a smartphone. The data source in this study uses a literature review method which comes from several sources, both national and international journals, using published articles from Google Scholar, Radiation Oncology Journal, PubMed, and Elsevier. In this research, birth photography is used as a facility for mothers going through normal childbirth. The aim is to entice mothers to become more interested and brave in going through natural childbirth with professional midwives at PMB
GROWTH AND DEVELOPMENT OF BLUEBERRY VARIETIES PLANTS INTRODUCED IN THE CLIMATIC CONDITIONS OF TASHKENT REGION Kurbanmuradov Akbar Choriyevich-Ph.D.; Namozov Ikhtiyor Choriyevich
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 6 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i6.672

Abstract

The duration of the growing season of blueberry varieties, which are introduced into the conditions of the central climate of Uzbekistan, is in the range of 213-221 days. In this case, the shortest period is 213 days in the Toro and Darrou varieties, the longest period is 220-221 days in the Patriot and Legasi varieties, and the duration of the growing season of the remaining varieties is in the range of 215-218 days
IMPACT OF MICRONUTRIENT DEFICIENCIES ON CHILD DEVELOPMENT Fatima Martoub Mohsen Abdel Reda; Fatima Qasim is an ignorant Hindu; Muhammad Baqir Abdel Hassan Abdel Zaid; Hawraa Ali Abdul Amir Saleh; Louay Qusay Reda Kazem
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 6 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i6.674

Abstract

Micronutrient deficiencies pose a significant threat to child development, affecting millions of children globally. This paper explores the critical role of essential vitamins and minerals in the physical, cognitive, and emotional growth of children. It highlights the prevalence and impact of deficiencies in key micronutrients such as iron, vitamin A, iodine, and zinc. The study examines how these deficiencies can lead to severe developmental issues, including impaired cognitive function, stunted growth, and weakened immune systems. By analyzing various case studies and intervention programs, the paper underscores the importance of addressing micronutrient deficiencies through comprehensive public health strategies. It advocates for policy initiatives aimed at improving nutrition education, fortifying foods, and ensuring equitable access to supplements, particularly in low- and middle-income countries. The findings emphasize that mitigating micronutrient deficiencies is crucial for fostering healthy development and unlocking the full potential of children worldwide

Page 13 of 23 | Total Record : 223

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