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Health Dynamics
Published by Knowledge Dynamics
ISSN : -     EISSN : 30065518     DOI : https://doi.orag/10.33846/hd
Core Subject : Health, Science,
Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health
Health Dynamics (ISSN: 3006-5518, online) is an open-access journal that publishes Original Research, Case Report, Literature Reviews, Short Communications, Commentary, Opinion, Book Review, Letter to Editor, and Scientific News in the areas of public health, medicine, dentistry, human nutrition, nursing, health administration etc.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 222 Documents
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Improved Lung Cancer Prevention Knowledge Among Older Adults Through Structured Health Education Ni Wayan Prema Revina Sutami; I Wayan Mustika; Ketut Sudiantara; Agus Sri Lestari; I Wayan Suardana; Suparji Suparji
Health Dynamics Vol 3, No 5 (2026): May 2026
Publisher : Knowledge Dynamics

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hd30506

Abstract

Background: Lung cancer remains a major global public health problem and is one of the leading causes of cancer-related mortality, particularly among the elderly who are more vulnerable due to age-related physiological decline and prolonged exposure to risk factors such as smoking and environmental pollutants. Despite ongoing preventive efforts, limited knowledge and awareness regarding lung cancer prevention among older adults continue to hinder effective control strategies. This study aimed to determine the effect of booklet-based health education on the level of knowledge regarding lung cancer prevention among the elderly. Methods: This study employed a quantitative pre-experimental design using a one-group pretest–posttest approach. The study was conducted in the working area of UPTD Puskesmas I East Denpasar, Bali, Indonesia. The sample consisted of 103 elderly individuals selected through purposive sampling. Primary data were collected using a structured questionnaire measuring knowledge levels, while secondary data included respondent characteristics. Data were analyzed using descriptive statistics and the Wilcoxon signed-rank test. Results: The results showed that prior to the intervention, the majority of respondents had poor knowledge (59.2%), which decreased to 9.7% after the intervention. Conversely, the proportion of respondents with good knowledge increased from 11.7% to 47.6%. The mean knowledge score also increased from 49.26 to 74.39, with a statistically significant difference (p = 0.001). Conclusions: In conclusion, booklet-based health education was associated with a significant improvement in knowledge regarding lung cancer prevention among the elderly. This intervention can be considered a practical and effective strategy for enhancing health literacy in community settings.
Evaluation of Nutritional Awareness, Hygiene Practices, and Lifestyle Factors on Health Outcomes and Academic Concentration Among Tertiary Level Students in Chattogram, Bangladesh Zarin Tasnim; Md. Mazharul Alam; Mehnaz Mashuk Prima; Tajwar Karim; Abdur Rahman
Health Dynamics Vol 3, No 3 (2026): March 2026
Publisher : Knowledge Dynamics

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hd30305

Abstract

Background: Nutritional habits, hygiene practices, and lifestyle attitudes are recognized as important decisive factors of health and academic performance among university students. However, available literature from developing countries, particularly Bangladesh, remains limited. This study aimed to evaluate the relationship between nutritional awareness, hygiene practices, lifestyle factors, and their effects on health outcomes and academic concentration among tertiary-level students in Chattogram City, Bangladesh. Methods: A cross-sectional study was conducted among 93 tertiary-level students selected through convenience sampling. Data were collected using a structured questionnaire covering demographic characteristics, dietary habits, hygiene practices, lifestyle factors, and academic performance indicators. Composite scores for hygiene and nutrition were generated by converting ordinal variables into numerical scales. Descriptive statistics (mean ± standard deviation) were calculated, followed by correlation analysis and multiple linear regression to assess associations between independent variables and outcomes like academic concentration and grade point average (GPA). Results: The mean age of participants was 20.51 ± 1.74 years. The average sleep duration, screen time, GPA, and academic concentration scores were 6.66 ± 0.91 hours, 5.39 ± 2.17 hours, 3.41 ± 0.42, and 6.58 ± 1.60, respectively. Correlation analysis showed weak relationships among variables, with sleep duration showing a weak positive association with academic concentration (r = 0.14) and GPA (r = 0.08), while screen time revealed a weak negative correlation with GPA (r = -0.07). Regression analysis pointed out that none of the examined factors were statistically significant (p > 0.05). Conclusions:The findings suggest that individual lifestyle, nutritional, and hygiene factors have limited independent influence on academic performance and concentration among students. Academic success cannot be explained by some specific lifestyle variables in isolation, but rather through complex interactions among multiple determinants.  Future studies with larger sample sizes and longitudinal designs are recommended to better understand these relationships. 
Strengthening the Capacity of Village Communities in Handling Health Crises Due to Disasters Through Participatory Action Research: Results of Community Service in Ngelang Sunarto Sunarto; Heru Santoso Wahito Nugroho; Suparji Suparji; Aries Prasetyo; Cantika Puteri Apriliana
Health Dynamics Vol 3, No 7 (2026): July 2026
Publisher : Knowledge Dynamics

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hd30703

Abstract

Ngelang Village in Kartoharjo District, Magetan Regency, has been designated a Disaster Resilient Village (Destana). However, its capacity to handle health crises remains limited, marked by weak coordination, the absence of an emergency command structure, and minimal training and simulation. The community service activity employed a Participatory Action Research (PAR) approach and involved 34 participants. Needs identification resulted in four priorities: establishing a command structure, developing a contingency plan, updating health vulnerability data, and creating a risk and vulnerability map. Intensive training was conducted over four days, totaling 30 training hours (JPL). The average pre-test score of 77.07 increased to 86.4 in the post-test, but decreased to 81.03 after one month, indicating challenges in knowledge retention. Participation was high, with over 59% of responses in the excellent category. Weaknesses were still evident in discussion engagement and problem-identification skills. Reflection showed that material understanding and practical skills were in the moderate category, while engagement was relatively high. The PAR intervention was effective in increasing knowledge and participation; however, the sustainability of the results requires strengthening retention strategies. Active participant involvement is crucial, but improvements are needed in discussion and problem analysis. The village government is committed to allocating the village budget (APBDes) for evacuation facilities, outreach, and regular simulations. The Destana Forum has agreed to make the training a regular biennial program and establish collaborations with health and disaster management agencies.
The Role of PD-1 and CTLA-4 Blockade in Immunotherapy: Mechanisms of Action and Therapeutic Efficacy in Overcoming Lung Cancer Immune Evasion Mojeeb Abdo Abdullah Qasem; Theresia Indah Budhy; Desak Gede Agung Suprabawati; Waode Fifin Ervina; Faheem Q. AL-Mojahid
Health Dynamics Vol 3, No 7 (2026): July 2026
Publisher : Knowledge Dynamics

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hd30702

Abstract

Lung cancer remains the leading cause of cancer-related mortality worldwide, with non-small cell lung cancer (NSCLC) accounting for approximately 85% of cases and small cell lung cancer (SCLC) representing a highly aggressive neuroendocrine subtype with a poor prognosis. Tumor cells evade immune surveillance by co-opting immune checkpoint pathways, principally programmed cell death protein 1 (PD-1) and cytotoxic T lymphocyte-associated protein 4 (CTLA-4). This review evaluates the mechanisms and therapeutic potential of PD-1 and CTLA-4 blockade in overcoming immune evasion in lung cancer. A structured narrative literature review synthesized evidence from preclinical studies, landmark clinical trials including KEYNOTE-001 and IMpower133, biomarker investigations, and mechanistic research on PD-1/PD-L1 and CTLA-4 pathways in NSCLC and SCLC. PD-1 suppresses effector T-cell activity and enhances regulatory T-cell function within the tumor microenvironment, while CTLA-4 attenuates T-cell priming through competitive B7 ligand binding. Immune escape is further mediated by HLA class I downregulation, impaired antigen presentation, immunosuppressive cytokine signaling, and tumor-infiltrating regulatory T cells. ICI monotherapy significantly improves overall survival in NSCLC with PD-L1 expression ≥50% compared with platinum-based chemotherapy. First-line atezolizumab plus chemotherapy extended median overall survival to 12.3 months, compared with 10.3 months in extensive-stage SCLC. Dual PD-1/CTLA-4 blockade produces synergistic antitumor responses; however, 70–85% of NSCLC patients develop primary or acquired resistance. PD-1 and CTLA-4 blockade has transformed the therapeutic landscape of lung cancer, yet resistance mechanisms, immune-related adverse events, and the absence of validated predictive biomarkers remain critical challenges. Future research must prioritize combination strategies, novel checkpoint targets, and multifactorial biomarker panels to broaden clinical benefit.
Analysis of Anemia Prevention Factors in Pregnant Women Based on Information-Motivation-Behavioral (IMB) Theory in the Work Area of the Kalianget Health Center Eka Mieri Kurniyati; Mujib Hannan; Zakiyah Yasin; Abd. Wahid
Health Dynamics Vol 3, No 6 (2026): June 2026
Publisher : Knowledge Dynamics

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hd30605

Abstract

Background: Anemia in pregnant women is one of the health problems that is still a challenge in Indonesia, including the Kalianget Health Center. Anemia can have a profound impact on both the mother and the fetus that is conceived. The prevention of anemia is highly dependent on pregnant women's knowledge, motivation, and behavior. This study analyzes the relationship between information and motivation for preventing anemia in pregnant women based on the theory of Information Motivation Behavior (IMB). Methods: The study used an observational design with a cross-sectional approach. The sample consisted of 35 pregnant women selected by simple random sampling. The research instrument used questionnaires and hemoglobin level checks. Results: showed that most respondents had moderate information and motivation. There was a significant relationship between information and anemia prevention (p = 0.000; r = 0.713) and between motivation and anemia prevention (p = 0.000; r = 0.743). Conclusion: It can be concluded that the higher the level of information and motivation of pregnant women, the better the anemia prevention behavior that is carried out. The IMB theoretical approach has been proven effective in supporting health promotion efforts to reduce the risk of anemia in pregnant women.
Artificial Intelligence for Precision Management of Lung Adenocarcinoma Abdullah Al Mamun
Health Dynamics Vol 3, No 6 (2026): June 2026
Publisher : Knowledge Dynamics

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hd30601

Abstract

Not mandatory
Nurses' Clinical Competence as a Predictor of Patient Safety Target Compliance in Surgical Procedures Hani Tuasikal; Inge Dhamanti; Mahmudah Mahmudah; Nursalam Nursalam; Ah Yusuf; Ratna Dwi Wulandari; Hari Basuki Notobroto
Health Dynamics Vol 3, No 6 (2026): June 2026
Publisher : Knowledge Dynamics

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hd30606

Abstract

Background: The implementation of patient safety goals in hospitals, including operating rooms, is inseparable from the competence of nurses. High levels of competence also contribute to improving the quality of nursing care and enhancing patient safety. This study aims to gain a deeper understanding of the relationship between the clinical competence of operating room nurses and the achievement of patient safety goals. Methods: This study used a cross-sectional design and collected data from seven private hospitals in Ambon City, with a sample of 66 surgical nurses. The sampling technique used was simple random sampling, a method of selecting participants from a population without regard to the strata within that population. Results: The clinical competence of surgical nurses was measured using three subdomains aligned with competency areas: ethical and legal professional practice and cultural sensitivity; nursing care provision and management; and personal and professional quality development. The frequency distribution of respondents was analyzed based on these clinical competence domains. There was a significant relationship between the clinical competence of surgical nurses and patient safety goals, particularly regarding surgical procedures. Conclusions: Clinical competence is a critical component of patient safety, as it helps ensure that nurses provide safe and effective care while promoting active involvement and participation in achieving patient safety goals.
Operationalizing One Health Through Primary Healthcare Abdullah Al Mamun
Health Dynamics Vol 3, No 7 (2026): July 2026
Publisher : Knowledge Dynamics

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hd30701

Abstract

Not mandatory
Human Factors Analysis and Traffic Accident Prevention Program for Motorcycle Drivers: A Systematic Review Dani Nasirul Haqi; Endang Dwiyanti; Yustinus Denny Ardyanto Wahyudiono; Bian Shabri Putri Irwanto
Health Dynamics Vol 3, No 1 (2026): January 2026
Publisher : Knowledge Dynamics

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hd30106

Abstract

Background: The human factor is the main factor in determining the success of traffic safety. The existence of human factors needs to be analyzed in more depth to create a more appropriate accident prevention program. This systematic review aims to investigate human factors, namely motorcycle drivers, causing traffic accidents and determine more effective accident prevention programs. Methods: The method used was a systematic review on electronic data sources such as ScienceDirect, ProQuest, PubMed, and Google Scholar using the keywords “human factor, traffic accident prevention program, and two-wheeled motorcycle driver”. Using the inclusion and exclusion criteria in the final stage, nineteen articles were found. Results: Human factors are the primary cause of traffic accidents involving motorcyclists, with two main aspects standing out most prominently. First, the high rate of traffic violations, such as speeding, running red lights, failing to maintain a safe distance, and aggressive driving behavior. Second, low compliance with the use of safety equipment, such as not wearing a standard helmet, protective jacket, gloves, or other safety gear. Ongoing specialized education and training programs are the most effective strategy. Conclusion: Human factors are the leading cause of traffic accidents, particularly among motorcyclists. The most effective preventive measure is through ongoing education and training programs.
Post-Cesarean Pain Intensity and Breastfeeding Success Within the First 24 Hours Postpartum: A Cross-Sectional Study Ni Putu Novi Fridayanti; I Komang Lindayani; Listina Ade Widya Ningtyas; Ni Nyoman Suindri; Ni Made Dwi Purnamayanti; Ashriady Ashriady
Health Dynamics Vol 3, No 7 (2026): July 2026
Publisher : Knowledge Dynamics

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hd30704

Abstract

Background: The relationship between post-sectio caesarea pain levels and breastfeeding success within the first 24 hours postpartum is an important concern because postoperative pain may inhibit early breastfeeding. Mothers who undergo sectio caesarea often experience limited mobility, discomfort, and disruption of the milk ejection reflex due to pain. This study aimed to determine the relationship between post-sectio caesarea pain levels and breastfeeding success within the first 24 hours postpartum at Dharma Kerti Hospital, Tabanan, in 2026. Methods: This study used a quantitative analytic design with a cross-sectional approach. The sample consisted of 35 post-sectio caesarea mothers selected using a purposive sampling technique. Pain levels were measured using the Numeric Rating Scale (NRS), while breastfeeding success was assessed using the LATCH method. Data were analyzed using Fisher's Exact Test with a significance level of α < 0.05. Results: The results showed that most respondents experienced mild pain (48.6%), followed by moderate pain (37.1%) and severe pain (14.3%). A total of 85.7% of respondents successfully breastfed, while 14.3% were unsuccessful. Statistical analysis showed a significant relationship between post-sectio caesarea pain levels and breastfeeding success within the first 24 hours postpartum (p < 0.001). Conclusion: Higher pain levels were associated with an increased risk of breastfeeding failure.

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