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Neurona
Published by Perhimpunan Dokter Spesialis Neurologi Indonesia
ISSN : 02166402     EISSN : 25023748     DOI : https://doi.org/10.52386/neurona
Core Subject : Health, Science,
Health Professions Medicine & Pharmacology Neuroscience
Neurona merupakan satu-satunya jurnal yang memuat perkembangan penelitian dan kasus terbaru bidang neurosains oleh Perhimpunan Dokter Spesialis Saraf (PERDOSSI) Pusat di Indonesia. Jurnal ini diterbitkan bulan Maret, Juni, September dan Desember. Bidang studi cakupan NEURONA meliputi: Stroke dan Pembuluh darah Neurotrauma Neuroonkologi Neuro Infeksi Neuro Behavior Neurorestorasi Neuropediatri Gangguan Tidur Nyeri Kepala Neurootologi Neuro Intervensi Neuro Intensif Neurogeriatri Gangguan Gerak Epilepsi Neuro Epidemiologi
Arjuna Subject : Kedokteran - Neurologi Klinis
Articles 14 Documents
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Search results for , issue "2026" : 14 Documents clear
GAMBARAN RADIOLOGIS GLIOBLASTOMA : LAPORAN KASUS yudhisman imran
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 42 No 3 (2026): Juni 2026
Publisher : PERDOSNI

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Abstract

ABSTRACT Background : Space Occupying Lesions (SOL) are pathological abnormalities within the intracranial space that can cause progressive neurological disorders. Intracranial SOL include cerebral contusions, hematomas, infarctions, abscesses, and tumors that grow in the intracranial space. According to the World Health Organization (WHO) 2021, glioblastoma is defined as a wild type isocitrate dehydrogenase (IDH) astrocytic tumor or grade 4 glioma, as determined by histological features and molecular markers. Glioblastoma is commonly found in the frontal, temporal, and parietal lobes. Patients with brain tumors often present as neuroemergencies due to increased intracranial pressure. Glioblastoma can be detected using a CT (Computed Tomography) scan or atau MRI (Magnetic Resonance Imaging) as the initial imaging modality. Case Description : A 43 year old man presented to the Emergency Department complaining of headaches that had persisted more than two weeks. The headaches had been persistent throughout the day and were progressively worsening. A neurological examination revealed compos mentis consciousness with left hemiparesis. A non-contrast head CT scan was performed, suggesting a cerebral abscess (DD)/cystic glioma. A contrast-enhanced CT scan revealed a diagnosis of glioblastoma multiforme. A craniotomy was performed, and the post-operative tissue section underwent pathologic examination, which concluded epithelioid glioblastoma and metastatic poorly differentiated carcinoma. Conclusions: Although brain imaging suggests glioblastoma, a definitive diagnosis cannot be made on the basis of radiographs due to their limitations in assessing the tumor's histological and molecular characteristics. In the latest WHO classification, the diagnosis of glioblastoma encompasses both histological features and molecular. These findings cannot be assessed solely on radiographs, necessitating tissue examination. Keywords: Brain Tumor, Glioblastoma,CT Scan
KERENTANAN STATUS GIZI PADA STROKE ISKEMIK AKUT: DAMPAK GABUNGAN DISFAGIA DAN GANGGUAN KOGNITIF Amriani Amriani; Ika Marlia; Nasrul Musadir
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 42 No 3 (2026): Juni 2026
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v42i3.911

Abstract

PEMILIHAN MONTASE TDCS KORTEKS MOTORIK DALAM PRAKTIK NEURORESTORASI: PERSPEKTIF PEMODELAN MEDAN LISTRIK Amanda Tiksnadi
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 42 No 3 (2026): Juni 2026
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v42i3.947

Abstract

Introduction: Various transcranial direct current stimulation (tDCS) montages have been used for primary motor cortex (M1) stimulation. However, montage selection is often based on clinical convention rather than differences in the resulting electric field distribution. Aim: To analize the electric field distribution characteristics of commonly used tDCS montages for left M1 stimulation and discuss their implications for neurorestorative practice. Electric field simulations were performed using SimNIBS based on the finite element method (FEM) and the Ernie Extended head model. Five montages were analyzed: C3–C4, C3–Fp2, C3–Fp1, C3–right deltoid (RDt), and C3–left deltoid (LDt), with the anode placed over C3 and a stimulation intensity of 2 mA. Regional analyses were conducted at C3, Cz, and C4. Distinct electric field distributions were observed across all montages. The C3–C4 montage produced the greatest involvement of the medial sensorimotor region and the contralateral hemisphere, whereas C3–Fp1 generated the most localized distribution within the target hemisphere. The C3–Fp2 montage produced the highest electric field intensity at the target region (C3). Extracephalic montages (C3–RDt and C3–LDt) demonstrated relatively lower contralateral hemispheric involvement compared with the bihemispheric montage. The location of the second electrode substantially influences electric field distribution within the sensorimotor network. Each montage exhibits distinct network recruitment characteristics, suggesting that montage selection should be tailored to the intended neuromodulatory objective and the underlying clinical condition.finite element method; FEM neuromodulation; neurorestoration; primary motor cortex; transcranial direct current stimulation; tDCS
ANGIOPLASTI BALON INTRAKRANIAL SEBAGAI PENCEGAHAN SEKUNDER STROKE ISKEMIK Yan Leo Tambunan
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 42 No 3 (2026): Juni 2026
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v42i3.956

Abstract

Background: Intracranial atherosclerotic disease (ICAD) is a major cause of recurrent ischemic stroke despite optimized aggressive medical management. Over the last decade, intracranial balloon angioplasty (IBA)—including submaximal angioplasty and drug-coated balloon (DCB)—has emerged as a “leave-nothing-behind” strategy that may lower restenosis and recurrent events compared with stenting. Objective: To evaluate the effectiveness and safety of IBA as secondary prevention for patients with symptomatic intracranial atherosclerotic stenosis (sICAS) and to compare outcomes with aggressive medical therapy and/or stenting. Method: We conducted a PRISMA-guided systematic literature review across Scopus, PubMed, and ProQuest (2015–2025). From 199 records (Scopus 78; PubMed 21; ProQuest 100), titles/abstracts were screened, full texts assessed, and data extracted in duplicate using a standardized form. Seventeen studies (RCT, prospective/retrospective cohorts, and systematic reviews/meta-analyses) were included for qualitative synthesis. Result: Across included studies, IBA—particularly submaximal angioplasty combined with modern medical therapy—reduced 30-day stroke/death and 12-month recurrent stroke versus medical therapy alone in eligible sICAS. DCB consistently showed lower restenosis and minimal residual stenosis versus conventional stenting without a safety penalty, while overall periprocedural complication rates with conservative dilation were low. Conclusion: Evidence from the 17 included publications supports IBA—both submaximal and DCB—as a safe and effective option for secondary prevention in carefully selected sICAS. Longer-term multicenter RCTs are warranted to standardize technique (target residual stenosis, inflation parameters) and confirm superiority over stenting or medical therapy alone. Keywords: intracranial balloon angioplasty; submaximal angioplasty; drug-coated balloon; secondary prevention; sICAS.

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