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Gedung A Lantai 1, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Kristen Krida Wacana Jl. Arjuna Utara No. 6, Duri Kepa, Kebon Jeruk, Jakarta Barat, Jakarta 11510
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Jurnal MedScientiae
Published by Universitas Kristen Krida Wacana
ISSN : -     EISSN : 28291166     DOI : https://doi.org/10.36452/jmedscientiae
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health
Jurnal MedScientiae adalah jurnal yang dikelola oleh Fakultas Kedokteran dan Ilmu Kesehatan Universitas Kristen Krida Wacana. Jurnal ini mempublikasikan artikel-artikel secara open access dalam lingkup bidang kedokteran dan kesehatan seperti kedokteran dasar, bioetika kedokteran, biologi sel, biologi molekuler, genetika, fisiologi, biokimia, bioinformatika, anatomi, farmakologi, kesehatan masyarakat, dan ilmu biomedik lainnya. Tim editorial menerima naskah berupa artikel penelitian, literature dan systematic review, dan laporan kasus. Naskah yang dikirimkan hendaknya belum pernah diterbitkan sebelumnya di jurnal maupun media yang lain dan disiapkan sesuai dengan template atau format yang telah ditentukan. Setiap naskah yang memenuhi kriteria jurnal akan direview oleh pakar yang sesuai (peer reviewer). Jurnal MedScientiae tidak mengenakan biaya selama proses mulai dari penerimaan naskah hingga publikasi. Jurnal MedScientiae terbit 3 kali dalam satu tahun, yaitu pada bulan April, Agustus dan Desember dengan cakupan keilmuan yang telah disebutkan di atas. Edisi pertama jurnal akan diterbikan di bulan Mei tahun 2022 dengan nomor ISSN 2829-1166.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 23 Documents
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Search results for , issue "Vol. 2 No. 2 (2023): August" : 23 Documents clear
The KARAKTERISTIK KLINIKOPATHOLOGI BERDASARKAN LOKASI KANKER KOLOREKTAL DI RUMAH SAKIT BETHESDA, YOGYAKARTA: - Elbert Hansyah Wibowo Wibowo
Jurnal MedScientiae Vol. 2 No. 2 (2023): August
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v2i2.2543

Abstract

Colorectal cancer has prevalence about 10% of all cancer that can cause death. Incident number of colorectal cancer in the US in 2021 about 104.270 colon cancer cases and 45.230 rectal cancer cases with death number was 52.980 lives. There were 1.544 patients diagnosed with colorectal cancer in RSUP Dr. Sarjito between year 2008-2017 among of them 820 male and 724 female.  This research used retrospective descriptive using medical record data of colorectal cancer patients between year 2016-2020, and data were analyzed using univariat and were displayed in the form of tabel and diagram. This research  used research variables, including: location of colorectal cancer, stage, age, gender, histopathological picture, and clinical symptoms. Colorectal cancer There were a total of 60 patients with details of right colorectal cancer patients being male (5 patients), moderate age range (4 patients), stages 3 and 4 (2 patients each), histopathological type of adenocarcinoma (4 patients), and symptoms clinical abdominal pain (4 patients).  The most common colorectal cancer is left colorectal cancer, with male gender, 40-64 years old, histopathological type of adenocarcinoma, and stage 4.
PENYEBAB DAN TATALAKSANA DALAM MENGATASI KELOID Dea Amelia Glorie; Wiwi Kertadjaya; Reni Angeline
Jurnal MedScientiae Vol. 2 No. 2 (2023): August
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v2i2.2798

Abstract

Pathological wound healing and pathological scar formation lead to functional and aesthetic losses. Keloids are excessive scars that grow beyond the boundaries of the original wound which is a fibroproliferative disorder. Keloids are difficult to treat because of the recurring nature of keloids and imperfect treatment of keloids can make keloids worse. Based on this description, this literature review was created by the author to explain the causes and treatments for keloid. The research articles reviewed are in the form of analytical reviews through the PubMed database. A total of 20 research articles were selected according to the purpose of writing this literature review. The main cause of keloids is trauma, injury or infection of the skin. Monotherapy for keloids isn’t recommended because of the higher recurrence rate compared to combination therapy. Several modalities for the treatment of keloids are surgical procedures, radiotherapy, antitumor/anticancer, calcium electroporation, corticosteroids, intermittent magnetic pressure, silicone gel, laser, Plasma Skin Regeneration, and cryotherapy. Excision is a modality that provides instant reduction in keloid size, but due to the high recurrence, other therapies must be given as combination therapy, namely corticosteroid injections or radiotherapy, which can reduce the recurrence rate after excision.
Gambaran Kadar Glukosa Darah Sewaktu pada Kalangan Biksu Buddhis di Kota Jakarta Barat dan Jakarta Pusat pada Tahun 2022 Arya Elbert Neil; Gracia J.M.T Winaktu; Rebecca Noerjani Angka; Luciana Budiati Sutanto
Jurnal MedScientiae Vol. 2 No. 2 (2023): August
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v2i2.2807

Abstract

The lacto-ovo vegetarian diet (VLO) is a diet consisting of plant-based foods such as vegetables, fruit and accompanied by the consumption of eggs and milk. There are many benefits of this diet, such as maintaining blood glucose levels, body fat levels, body weight, body mass index, pancreatic beta cell performance which can maintain normal blood glucose levels. This research was conducted at the Ekayana Arama Temple in West Jakarta and the Mahayana Temple which is located in Central Jakarta. The method for this research is descriptive research with cross sectional study using purposive sampling method. The results of the study consisted of 19 men and 12 women with 21 years as the youngest age and the oldest age is 77 years. The conclusion of this study is that the hypothesis is accepted, the lacto-ovo vegetarian diet can maintain blood glucose levels remain normal, mean 115.84 mg/dL with a minimum value of 82 mg/dL and 164 mg/dL as the maximum value.
Tinjauan Pustaka Faktor Risiko Penyebab Terjadinya Hepatoseluler Karsinoma Akibat Hepatitis B Gitana Gezatania; Suzanna Ndraha; Marcel Antoni
Jurnal MedScientiae Vol. 2 No. 2 (2023): August
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v2i2.2817

Abstract

Hepatitis B is a liver infection caused by the hepatitis B virus (HBV) which has the potential to threaten a person's life. According to WHO, hepatitis B is a major global health problem that causes acute and chronic infections. Chronic hepatitis B has a very high risk of developing hepatocellular carcinoma. The purpose of writing this literature review is to determine the risk factors for the occurrence of hepatocellular carcinoma in someone who is infected with HBV. Methods of data collection through the Pubmed website, Wiley Online Library, and Springer Link from 2012-2022, 10 journals were found to be analyzed in writing this literature review. From the 10 journals analyzed, it can be concluded that type 2 diabetes mellitus in someone who is infected with HBV is an important risk factor that increases the risk of developing hepatocellular carcinoma.
Bimekizumab Sebagai Pengobatan Pilihan Psoriasis Vulgaris Tipe Plak Jenifer Putri Sianto; Rompu Roger Aruan; Grace Pudjiadi Widodo; Arini Astari Widodo
Jurnal MedScientiae Vol. 2 No. 2 (2023): August
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v2i2.2818

Abstract

Psoriasis is a chronic inflammatory skin disease which is associated with genetic predisposition and autoimmune pathogenic traits. This disease is characterized with erythematous plaque and silvery scales that is severely itchy, swells, and is painful, which causes patients to have a poor quality of life. In the last years, there has been several effective therapies that is developed to treat psoriasis, but despite this, a proportion of patients do not respond or lose respond over time towards these therapies. However, there is a novel therapy found which is Bimekizumab, it is the first monoclonal antibody that is designed to target both IL-17A and IL-17F simultaneously. Bimekizumab is proved as the choice of therapy for psoriasis that reduces psoriasis plaque patients PASI score up to 100 with a minimal and mild side effects, and no immunogenicity detected. It also works in a shorter amount of time to reach PASI 90 as early as week 4 and can maintain response up to week 52. This objective of this literature review is to discuss about the superiority of bimekizumab compared to other therapies for psoriasis vulgaris.
Uji Daya Hambat Ekstrak Teh Hijau (Camellia sinensis) Terhadap Pertumbuhan Candida albicans Secara In Vitro Chaidir Ali Paradise; Dian Ayu Fitriani; Rolly Riksanto Bahtiar
Jurnal MedScientiae Vol. 2 No. 2 (2023): August
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v2i2.2819

Abstract

Candidiasis is any  infection  caused by Candida albicans and other species of the genus Candida. Bioactive compounds such as flavonoid, tannin and saponin have antifungal activity. Several studies have investigated the bioactive compounds  in green tea leaves (Camellia sinensis). Objective is to determine the ability of  green tea leaf extract (Camellia sinensis) to combat the growth of Candida albicans. A true experimental study. Green tea leaf (Camellia sinensis) and Candida albicans extract were used as the sample. Results According to the Davis and Stout method, green tea (Camellia sinensis) extracts at concentrations of 25% and 75% showed moderate inhibition of Candida albicans growth on the first day of  Candida albicans incubation. , while 50% concentration showed strong inhibition. against the growth of Candida albicans and on the second day at concentrations of 25%, 50% and 75%  the growth of Candida albicans was not prevented. While the positive control using nystatin strongly inhibited and the negative control did not inhibit the growth of Candida albicans on the second day. first and second. Green tea leaf (Camellia sinensis) extract effectively inhibits the growth of Candida albicans during incubation.
The Potential of Adeno-associated virus Vector Gene Therapy for Achromatopsia Farianti Wiranda; Grace Marta Tanjung; Yudha Pandapotan; Santi Anugrahsari
Jurnal MedScientiae Vol. 2 No. 2 (2023): August
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v2i2.2828

Abstract

Achromatopsia, also known as color blindness, is the inability to distinguish certain colors. Where this is the inability of the eye cone cells to capture a certain color spectrum due to genetic factors and certain diseases. Abnormalities in the anatomical structure of the eye located on the retina and inherited recessively. These mutations lead to functional loss and slowly progressive degeneration of the cone photoreceptors. Treatment for color blindness is currently limited to genetic counseling, glasses or colored contact lenses. Genetic therapy methods are currently being developed targeting the retinal organs using recombinant adenovirus vectors. The results of research conducted on animals found an improvement in the function of cone cells so that gene therapy is a promising modality in the future.
Tinjauan Pustaka terhadap Tatalaksana Terkini Ulkus Kornea Jamur Akibat Salah Penggunaan Lensa Kontak Satrio Arief Setiawan; Muhamad; Santi Anugrahsari Anugrahsari
Jurnal MedScientiae Vol. 2 No. 2 (2023): August
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v2i2.2842

Abstract

Microbial keratitis can cause corneal ulcers that can threaten vision. Keratitis is the leading cause of global corneal blindness with an estimated incidence of 2.5-799 cases per 100,000 population/year. Corneal ulcers contribute 5% of blindness worldwide and are the most common cause of corneal blindness in the developing countries. This is a review over articles from electronic databases which focuses on the topic relevance, research methods, subjects, and the results. The data were collected from NCBI, AAOJournalt and Google Scholar with keywords “Fungal”, “Corneal Ulcer”, “Treatment”, “Contact Lens”, “Jamur”, “Ulkus Kornea”, “Terapi”, and “Lensa Kontak”. The inclusion criteria are published from January 2012 to July 2022, a study of humans, available in full text, written English or Indonesian. Natamycin 5% is effective in the treatment of fungal keratitis, voriconazole is more effective against fungal keratitis, and oral posaconazole can serve as an effective treatment for refractory Paecilomyces keratitis, which is resistant to conventional therapy. If the use of drugs that are not enough to treat fungal keratitis, requires action intervention. In treatment with action there is novelty in the action of the combination of CLX and acellular porcine corneal stroma (APCS). Keywords: literature review, management, microbial keratitis
Mekanisme Kerja Prostaglandin Analog Terhadap Jalur Uveosklera dan Efeknya Untuk Menurunkan Tekanan Intra Okular Julian Tanri; Daberto Andrias; Edgar Christoffer Hasoloan; Yunia Gracia Sesa; Santi Anugrahsari
Jurnal MedScientiae Vol. 2 No. 2 (2023): August
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v2i2.2844

Abstract

High Intraocular Pressure (IOP) which is > 21 mmHg could damage optical nerves which could results in blindness. High IOP is often caused by an obstruction of the eye ball fluid circulation which is called the Aquoeus Humour. In this era, decreasing IOP is still a main focus during therapy. The application of this therapy however is still a challenge because of the lack of drug obedience especially because of the side effects. This review is intended to provide patient a complementary medication to fulfill their therapy. Literature references are acquired through online science database search engine using Google Scholar, Science Direct, and Pubmed. This review includes 9 journals, with all articles conlcuded that prostaglandin analogues are the best choice in order to decrease IOP. Prostaglandin analogue functions as to repair the outflow of the uveoscleral pathway. Latanoprost 0.005% and latanoprostene bunod 0.024% are the best choice of prostaglandin analogue as a therapy for glaucoma, ocular hypertension, and many other diseases that increases IOP. The side effects of the prostaglandin analogue don’t appear often in patients and the side effects were shown to be mild which is considered preferable and safe decision for therapy.
Prevalensi Hipertensi pada Aplikator Pestisida dan Faktor yang Berkontribusi: Studi Potong Lintang Jen Fuk Liem; Apricylia Gloria Elizabeth Lumanauw; Yosephin Sri Sutanti; Johannes Hudyono
Jurnal MedScientiae Vol. 2 No. 2 (2023): August
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Ukrida

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v2i2.2855

Abstract

The purpose of this study is to determine the prevalence of high blood pressure (HBP) and the contributing factors in pesticide applicators in Cibodas Village, where chemical pesticides are widely utilized. This cross-sectional study included 90 pesticide applicators in total. The information on individual and occupational characteristics was gathered using a structured interview-administered questionnaire. An upper-arm digital blood pressure monitor was used to measure blood pressure. Data were presented descriptively, and statistical analysis was performed using the chi-square and multiple logistic regression. The majority of participants were men. 94% of individuals used a combination of pesticides on a regular basis. In this study, the prevalence of HBP was 48.9%. High BP was associated with age > 44 years, and a high exposure group. These results support the idea of the importance of multisectoral collaboration in providing knowledge about the potential health effects of exposure to pesticides and comprehensive training on the proper handling of pesticides in agriculture.

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