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Medicina Biomedica Journal
Published by Universitas Muhammadiyah Sumatera Utara
ISSN : 28278275     EISSN : 28278275     DOI : -
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Medicina Biomedica Journal is a peer-reviewed, open-access journal that publishes original research articles, review articles, and interesting case reports in the field of biomedical research aimed to publish a high-quality scientific paper including original research papers, case reports, reviews, short communication, and technical notes. This journal welcomes the submission of articles that offering a sensible transfer of basic research to applied clinical medicine. Medicina Biomedica Journal covers the latest developments in various fields of biomedicine with special attention to medical sciences, genetics, immunology, environmental health, toxicology, bioinformatics, and biotechnology as well as multidisciplinary studies. The views of experts on current advances in biomedicals and molecular/cell biology will be also considered for publication as long as they have a direct clinical impact on human health. The journal is intended as a medium of communication for those who were interested to study health, among others, for researchers, educators, students, and the public generally who have an interest in it. The journal is trying to meet the growing need to study health and to achieve a high impact factor in the development of science and technology.
Arjuna Subject : Kedokteran - Biokimia, Kedokteran
Articles 5 Documents
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Search results for , issue "Vol 1, No 1 (2022)" : 5 Documents clear
POST-SURGICAL MEASURES DURING THE COVID-19 PANDEMIC Suhaymi, Ery
Medicina Biomedica Journal Vol 1, No 1 (2022)
Publisher : Medicina Biomedica Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/mbj.v1i1.8111

Abstract

Coronavirus Disease 2019 (COVID-19) has a very diverse clinical presentation ranging from asymptomatic, mild, moderate to severe symptoms and even death. The increase in the number of cases took place quite quickly and spread in a short time. The current COVID-19 pandemic has major consequences for healthcare services. Strict adherence to the use of Personal Protective Equipment (PPE), and environmental hygiene improves safety and prevents virus transmission. Postoperative management is an important phase for patients with suspected/confirmed COVID-19 because it can be associated with slower recovery, a longer length of stay, and more complications. Surgeons, nurses, and medical staff have equal responsibilities in postoperative management. Postoperative consultations can be carried out via telemedicine to perform follow-up surgery on patients with clinical COVID-19. The use of telemedicine-based services prevents the risk of potential exposure to medical personnel. Taking the recommended steps in general surgical services can optimize the health services provided to confirmed COVID-19 patients and reduce the risk of occupational transmission to other patients and health professionals
THE RELATIONSHIP OF GRADING AND HISTOPATHOLOGY WITH RESULTS OF HER-2 PATIENTS' IMMUNOHISTOCHEMICAL EXAMINATION BREAST CANCER AT DR PIRNGADI MEDAN REGIONAL GENERAL HOSPITAL IN 2018-2019 Mustika, Suryani Eka; Pangestuti, Dewi
Medicina Biomedica Journal Vol 1, No 1 (2022)
Publisher : Medicina Biomedica Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/mbj.v1i1.8086

Abstract

Basic Health Research Data 2019 explains that breast cancer prevalence that occurs in Indonesia is the second malignancy phenomenon that often afflicts women with a percentage of 0.5%, and ranked first cervical cancer as much as 0.8%. To choose and predict the prognosis, immunohistochemical examination becomes part of the mandatory examination effort. The general purpose of this study is to test the relationship of grading histopathology and histopathology types with the results of the HER-2 immunohistochemical examination of breast cancer patients at Dr. Pirngadi Medan Hospital in 2018-2019. This type of research is observational analytics conducted using the Cross- Sectional method. Secondary research data in the form of breast cancer patients in the Anatomical Pathology section of Dr. Pirngadi Medan Hospital year 2018-2019. How to take a sample by total sampling method. The statistical test used in the study is the Chi-square test. The study found 66 cases. Breast cancer cases are most common in the age range between 40 to 49 years (43.9%). The most common stages are in stage III (53.0%). This type of histopathology is found in invasive ductal carcinoma (84.8%). The most histopathological grading was grade II (63.6%). HER-2 test results found that the majority of patients had HER-2 +3 (positive 3) (59.1%). As for the Chi-Square test, if p ≤ 0.05 found a significant association and if p ≥ 0.05 did not have a significant association. There is no significant association between the type of histopathology and the results of HER-2 immunohistochemical examination (p = 0.208) and there is no significant association between grading histopathology results of HER-2 immunohistochemical examination (p = 0.492).
EARLOBE KELOID: A REVIEW OF TREATMENT OPTIONS Batubara, Dian Erisyawanty
Medicina Biomedica Journal Vol 1, No 1 (2022)
Publisher : Medicina Biomedica Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/mbj.v1i1.9202

Abstract

Earlobe keloids are fibrous proliferations that show high recurrency. Therefore these benign lessions become one of the challenging and frustrating problem in wound healing. This affect people worldwide with different rases. The treatment of earlobe keloid is still challenging. Many different treatment options have been used to reduce the recurrency of earlobe keloid with various results, such as surgical excision, injection of ingtralessional corticosteroid and cryotherapy, however no single treatment modalities have been given satisfying results. In this artcle, we reviewed various treatment options of earlobe keloid from many different countries.
USE OF CHLOROQUINE ON COVID-19 VIRUS INFECTION IN INDONESIA: STUDY OF LITERATURE Ansyari, Dedi
Medicina Biomedica Journal Vol 1, No 1 (2022)
Publisher : Medicina Biomedica Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/mbj.v1i1.9186

Abstract

BACKGROUND: COVID-19, which is caused by a new type of coronavirus, namely SARS-CoV-2, has become a disease that causes a public health emergency that is troubling the world. Chloroquine was initially reported as a potentially useful drug for COVID-19. The use of chloroquine has been reported in various countries in the world and also in Indonesia.AIM: This literature study aims to trace the use of chloroquine at the beginning of the COVID-19 pandemic until recently.METHODS: The method used is through searching articles published in national and international journals within the last 3 years.RESULTS AND CONCLUSION: From the search results, it can be concluded that chloroquine has not been proven to be useful in the management of COVID-19 patients and can cause severe side effects, its use is no longer recommended by WHO and also in Indonesia
THE POTENTIAL OF EPIDERMAL GROWTH FACTOR RECEPTOR MOLECULES AS PREDICTORS OF CLINICAL STAGE AND PROGNOSIS OF SQUAMOUS CELL CARCINOMA IN MEDAN CITY Hasibuan, Ariq Muflih Halim; Pramesti, Tisya Amanah; Dwiyanti, Atika
Medicina Biomedica Journal Vol 1, No 1 (2022)
Publisher : Medicina Biomedica Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/mbj.v1i1.8117

Abstract

Squamous cell carcinoma (SCC) is a non-melanoma skin malignant tumor originating from the suprabasal keratinocytes of the epidermis. Exposure to ultraviolet radiation is known to be one of the main triggers so that the place of predilection for this malignancy is an area that is often exposed to sunlight, especially the head and neck. Assessing the potential of the Epidermal Growth Factor Receptor (EGFR) molecule in predicting the clinical stage and prognosis of squamous cell carcinoma of the skin. This study used 40 samples of keratinized and non-keratinized Squamous Cell Carcinoma patients who were then given EGFR staining by immunohistochemistry. The result of staining on EGFR by immunohistochemistry is brown, whereas if it appears blue, the result is negative. The relationship of EGFR expression from 40 slides of SCC collected with EGFR immunohistochemical staining found 6 malignant tumors (15%) negative EGFR, then 14 malignant tumors (35%) showed weak grade (positive 1), 6 malignant tumors (15%) showed moderate expression level (positive 2) and 14 malignant tumors (35%) showed strong expression (positive 3). The test results showed a significant relationship between the level of EGFR with the clinical stage of squamous cell carcinoma as indicated by the value of p = 0.030 ( 0.05). The analysis was analyzed using the two-tailed Bivariate Correlation test. Expression of EGFR molecules on immunohistochemical staining of SCC of the skin can be used to determine the clinical stage of SCC of the skin.

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