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Journal of Diverse Medical Research: Medicosphere
Published by Universitas Pembangunan Nasional Veteran Jawa Timur
ISSN : -     EISSN : 30639433     DOI : https://doi.org/10.33005
Core Subject : Health, Science, Social, Engineering,
Immunology & microbiology Mechanical Engineering Medicine & Pharmacology Public Health Social Sciences
Journal of Diverse Medical Research is an open access and peerreviewed journal published every month by Faculty of Medicine Universitas Pembangunan Nasional Veteran Jawa Timur. This journal is a dissemination medium for research result from various areas in medical science.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 115 Documents
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Implementation Of Mobile Application-Based Health Education For Hypertension Prevention In Young Adults: A Literature Review syah ariq zaidaan najich
Journal of Diverse Medical Research : Medicosphere Vol. 3 No. 1 (2026): Journal of Diverse Medical Research : Medicosphere 2026
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v3i1.291

Abstract

Hypertension among young adults is increasing due to modern lifestyles, yet conventional health education is often ineffective for this digital-native generation. This narrative review summarizes evidence from 2020–2025 on the effectiveness of mobile application-based health education for improving hypertension prevention behaviors and lowering blood pressure in young adults. Fifteen publications (meta-analyses, RCTs, feasibility studies, and protocols) were reviewed, focusing on mHealth interventions incorporating education, self-monitoring, reminders, feedback, and behavior change techniques (BCTs). Most studies found that apps with interactive educational features, blood pressure monitoring, adaptive reminders, and personalized feedback improved sodium intake, physical activity, and medication adherence. Meta-analyses reported an average systolic blood pressure reduction of 4–6 mmHg compared to controls. The highest effectiveness was seen in multi-component interventions lasting 3–6 months that applied BCTs such as goal setting, performance feedback, and self-monitoring. In conclusion, mobile app-based education is effective for hypertension prevention in young adults when designed with BCT principles. Implementation in campus and workplace settings offers a pragmatic strategy to expand the reach of hypertension prevention for young populations.
Dash vs Medditeranean Diet: A Comparative Analysis Of Blood Pressure Reduction In Hypertension: A Literature Review Dimas Agung Prihanggara
Journal of Diverse Medical Research : Medicosphere Vol. 3 No. 1 (2026): Journal of Diverse Medical Research : Medicosphere 2026
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v3i1.293

Abstract

Hypertension is a major global public health problem, and non-pharmacological management through dietary intervention is a key strategy. The DASH diet and the Mediterranean diet are both frequently recommended, but direct comparison of their superiority requires further analysis. This literature review critically compares evidence from five major studies examining the effectiveness of both diets in various clinical contexts. The synthesis shows heterogeneous findings. High-quality randomized controlled trials indicate that the Mediterranean diet combined with salt restriction achieves greater blood pressure reduction than the DASH diet. However, cross-sectional studies among patients already on antihypertensive medication found no significant association for either diet, suggesting a possible pharmacological ceiling effect. Confounding variables such as study population (adults vs. adolescents) and study design (RCT vs. observational) play an important role in interpreting results. In conclusion, both diets effectively lower blood pressure, but the Mediterranean diet shows superiority in specific clinical contexts, particularly when combined with sodium restriction. The Mediterranean diet may also offer more holistic cardiovascular benefits. Optimal dietary choice should be tailored to the patient's clinical profile, therapeutic goals, and overall management context.
Effectiveness of Education Through TikTok Social Media in Increasing Anemia Understanding Among Adolescent Girls: A Literature Review Salsabilla Cathabell Yudinda; Aristanto Prambudi; Ahmad Syarif
Journal of Diverse Medical Research : Medicosphere Vol. 3 No. 1 (2026): Journal of Diverse Medical Research : Medicosphere 2026
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v3i1.296

Abstract

Anemia remains a common health issue among adolescent girls, affecting their quality of life and academic performance. Conventional educational methods are often ineffective for the digital generation, making TikTok a potential alternative platform for engaging health education. This systematic literature review, based on the PRISMA 2020 framework, evaluated the effectiveness of TikTok-based educational interventions in improving knowledge and attitudes regarding anemia prevention among adolescent girls. Article searches were conducted through PubMed, Google Scholar, ResearchGate, and Mendeley for publications from 2021 to 2025, yielding seven studies that met inclusion criteria. Most studies reported increased knowledge following intervention, with average improvements of 20–45%. Six of seven articles demonstrated statistically significant effects on knowledge and attitudes. Short video formats combining visual and audio elements facilitated comprehension and information retention. Integrating TikTok with supporting media such as infographics improved understanding by up to 30% compared to using a single medium. In conclusion, TikTok is an effective medium for delivering health education on anemia to adolescent girls.
THE ROLE OF FERMENTED FOODS IN REGULATING GUT MICROBIOTA AND MENTAL HEALTH: A Literature Review Kadek Ardhyani Widya Ningrum; Aristanto Prambudi
Journal of Diverse Medical Research : Medicosphere Vol. 2 No. 12 (2025): Journal of Diverse Medical Research : Medicosphere 2025
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v2i12.301

Abstract

Background: Scientifically, fermentation is the process by which microorganisms convert sugar into alcohol and organic acids, which extends the shelf life of food. Today, the field of Nutritional Psychiatry has emerged to identify food components that are important for mental health, emphasizing that the complex interaction between nutrition and brain function highlights the need for a multidisciplinary approach. Objective: To explore the role of fermentation-based diets in regulating gut microbiota and their impact on mental health. Methods: The research method used was a literature review, with five journals reviewed. Results: Based on the five research journals reviewed, the main findings centered on the crucial and comprehensive relationship between gut microbiota, nutrition (diet), and mental health. The first journal introduced psychobiotics, specific live microorganisms that provide therapeutic benefits for mental disorders by increasing the production of important neurotransmitters such as dopamine and serotonin in the gut. The second and fourth journals explicitly show a strong correlation between a healthy diet and mental well-being. The third journal specifically discusses the role of fermented foods in Nutritional Psychiatry. The fifth journal also discusses lifestyle and nutritional neuroscience related to mental health. Conclusion: There is a close relationship between gut microbiota, diet, and mental health, which indicates the potential of nutritional and psychobiotic interventions in the prevention and treatment of mental disord
The Effectiveness of Probiotics as Adjuvant Therapy in Children with Autism Spectrum Disorder: A Literature Review FAKHIRAH NAILAH; Alya Raguan Al'Habsyi; Siti Wahyu Windarti
Journal of Diverse Medical Research : Medicosphere Vol. 3 No. 1 (2026): Journal of Diverse Medical Research : Medicosphere 2026
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v3i1.308

Abstract

Autism Spectrum Disorder (ASD) is a complex developmental disorder associated with gastrointestinal and neuropsychological disturbances. The growing understanding of the gut microbiota role via the gut–brain axis has opened opportunities for using probiotics as adjuvant therapy in managing ASD. This literature review aims to evaluate the effectiveness of  Lactobacillus probiotics as adjunct therapy in children with ASD. A systematic literature search was conducted using the PICO framework and relevant keywords for sources published between 2021 and 2025. Of 22 screened articles, eight studies met the inclusion criteria and were analyzed. Results suggest that  Lactobacillus probiotics show promising effects as adjunct therapy in ASD management. They help restore gut microbiota balance, increase beneficial species such as Bifidobacterium longum and  Lactobacillus spp., and reduce gastrointestinal symptoms including diarrhea and constipation. Neuropsychological improvements include enhanced social responsiveness and reduced anxiety, mediated by microbiota modulation, neuroactive metabolites, and immune system regulation. Additionally, probiotics support neurocognitive and behavioral enhancements via the gut–brain axis, measurable through EEG biomarkers. Minimal side effects and a high safety profile make probiotics a safe and feasible adjunct to conventional treatment. In conclusion, probiotics have potential as a sustainable supportive therapy; however, further high-quality studies with longer durations are required to confirm clinical benefits and fully understand the underlying mechanisms.
Impact of Household Waste on Public Health: A Literature Review Nayla Canthyka Yuniaf yuniaf
Journal of Diverse Medical Research : Medicosphere Vol. 3 No. 2 (2026): Journal of Diverse Medical Research : Medicosphere 2026
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v3i2.222

Abstract

Household waste has become an increasingly prominent environmental and health problem along with population growth, urbanization, and changes in people's consumption patterns. This research uses the literature review method. Household waste is a complex environmental problem, requiring an integrated approach through outreach to increase public awareness of good management. The 3R principle (Reduce, Reuse, Recycle) is applied by reducing the amount of waste, utilizing items that are still useful, and separating waste for recycling. Separation of waste from its source, reducing the use of single-use plastics, as well as support for modern technology and government policies such as Extended Producer Responsibility (EPR) are very important. Waste bank programs and community-based management encourage active community participation in creating sustainable solutions to waste problems.
The Role of Telemedicine in Managing Patients During the COVID-19 Pandemic: A Systematic Review of Clinical Applications and Challenges: A Literature Review NAUVAL LAZUARDI PRATAMA
Journal of Diverse Medical Research : Medicosphere Vol. 3 No. 2 (2026): Journal of Diverse Medical Research : Medicosphere 2026
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v3i2.226

Abstract

The COVID-19 pandemic has accelerated the adoption of telemedicine, improving access to remote healthcare, chronic disease management, and health education. However, its effectiveness varies, particularly for conditions requiring physical assessment. This systematic review evaluates the role of telemedicine during the pandemic, its benefits, challenges, and future implications. Telemedicine has proven effective in consultations and patient education but remains limited in physical examinations. Hybrid healthcare models integrating telemedicine and in-person visits are recommended to ensure sustainable healthcare delivery post-pandemic.
Technological Innovations for Efficient Disaster Management and Healthcare Response: A Literature Review Rika Yuliwulandari
Journal of Diverse Medical Research : Medicosphere Vol. 3 No. 2 (2026): Journal of Diverse Medical Research : Medicosphere 2026
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v3i2.230

Abstract

Disasters pose significant challenges to global health systems. Traditional methods of disaster management often struggle with efficient resource allocation and communication, especially in densely populated metropolitan areas. Technological innovations, such as GIS, UAVs, and VR, offer new opportunities to address these challenges. This study assesses the combined impact of technologies on improving healthcare service delivery and resource management during disasters, particularly in urban environments. A systematic review was conducted using the PRISMA-ScR framework. The research identified and analyzed studies from databases such as PubMed, Scopus, Sage Journals, and Google Scholar, focusing on technology-based disaster management interventions between 2020 and 2024. The review included eight studies that demonstrated significant improvements in disaster preparedness and response through the use of technologies. These technologies enhanced real-time decision-making, reduced response times, and improved the allocation of healthcare resources. However, the studies also highlighted issues with scalability, interoperability, and the lack of real-world testing. The integration of technologies has the potential to revolutionize disaster management practices. Despite the advancements, further research is needed to address the scalability and operational challenges that limit the full deployment of these technologies in real-world disaster scenarios.
Hypoxia: Adaptation Mechanisms and Their Impact on Organs Rifda El Mahroos; Shellya Puti Sudesty; Rifka Wangiana Yulia Putri
Journal of Diverse Medical Research : Medicosphere Vol. 3 No. 3 (2026): Journal of Diverse Medical Research : Medicosphere 2026
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v3i3.249

Abstract

Background: Hypoxia is a decrease in tissue oxygen that induces the activation of hypoxia-inducible factor (HIF) and cellular responses such as metabolic changes, angiogenesis, and inflammatory modulation. This initial adaptive response can become maladaptive with prolonged or repeated exposure. Methods: This article is a narrative review that examines literature from 2015–2025 from PubMed, ScienceDirect, and Google Scholar. Searches were conducted using keywords related to "hypoxia," "hypoxia-inducible factor (HIF)," "cellular adaptation," and "organ impacts," with selection based on relevance and scientific quality. Discussion: Hypoxia has various exposure patterns (acute, chronic, and intermittent) that trigger a body response through the activation of oxygen sensors and gene regulation by HIF. In the initial stages, the body attempts to maintain stable cell function. However, prolonged or repeated exposure renders this adaptive response ineffective and leads to tissue disruption. These impacts are seen in various organs, such as changes in heart structure, pulmonary vascular alterations, an increased tendency for fibrosis in the liver and kidneys, and a decreased integrity of the gastrointestinal epithelial barrier, all of which can contribute to disease. Conclusion: Hypoxia is a complex biological stimulus with dualistic effects that depend on the duration and intensity of exposure. This understanding is crucial for improving diagnostic and therapeutic strategies related to hypoxia. Keywords: hypoxia, HIF pathway, oxidative stress, organ dysfunction, inflammation
Ultra-Processed Food Consumption Patterns as an Early Risk Factor for Obesity and Cardiovascular Disease in Today's Adolescents: A Literature Review Krishna Artanto
Journal of Diverse Medical Research : Medicosphere Vol. 3 No. 2 (2026): Journal of Diverse Medical Research : Medicosphere 2026
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v3i2.290

Abstract

Modern dietary shifts have increased ultra-processed food (UPF) consumption, particularly among adolescents, raising concerns about obesity and cardiovascular disease (CVD) risk. This review analyzes the relationship between UPF intake and obesity and CVD risk in adolescents based on evidence from observational and cohort studies conducted in Korea, Brazil, Canada, and Indonesia. Key parameters included UPF contribution to total energy intake, body mass index (BMI), waist circumference, and blood pressure. The analysis found that UPF accounts for up to 40% of daily energy intake in adolescents. High UPF consumption significantly increased the risk of central adiposity (OR: 1.9) and high cardiovascular risk (OR: 3.77). Consistent associations were observed across countries for increased risk of obesity, hypertension, and diabetes. In Indonesia, over 80% of adolescents regularly consume UPF, with 29% experiencing overnutrition. In conclusion, high UPF consumption is strongly associated with increased obesity and cardiovascular risk from adolescence. Targeted nutritional interventions and public health policies to restrict UPF intake are urgently needed to mitigate long-term health impacts.

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