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Fakultas Farmasi UMI, Kampus II UMI, Jl. Urip Sumoharjo No.225, Panaikang, Panakkukang, Kota, Makassar,, Panaikang, Kec. Panakkukang, Macassar, Sulawesi Selatan 90231
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MPSJ
Published by Universitas Muslim Indonesia
ISSN : -     EISSN : 29870887     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Makassar Pharmaceutical Science Journal merupakan salah satu jurnal yang dikelola oleh Fakultas Farmasi Universitas Muslim Indonesia yang terbit pertama kali pada bulan Maret 2023. Makassar Pharmaceutical Science Journal merupakan jurnal ilmiah yang terbit secara on-line dan menerbitkan artikel atau karya ilmiah hasil penelitian dalam bidang farmasi sains.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 14 Documents
 1   2 
Search results for , issue "Vol 2 No 3 (2024)" : 14 Documents clear
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL AKAR BAJAKAH TAMPALA (Spatholobus Littoralis Hassk) MENGGUNAKAN METODE PEREDAMAN RADIKAL BEBAS DPPH Sari, Wina Astri; Tahir, Masdiana; Baits, Muzakkir
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.271

Abstract

Bajakah tampala (Spatholobus littoralis Hassk.) is a plant that lives on vines in tropical areas. This plant comes from Sebuku Village, North Kalimantan. The Bajakah Tampala plant contains saponins, flavonoids and tannins. The roots of the Bajakah Tampala plant are thought to have strong antioxidant activity which is able to reduce the activity of free radicals. The aim of this research is to analyze the antioxidant activity of Bajakah Tampala roots using the DPPH reduction method using a UV Vis spectrophotometer which is based on calculating the IC50 value. The results of this study indicate that the ethanol extract of Bajakah Tampala roots has antioxidant activity against DPPH free radicals with an IC50 value of 9.206 µg/mL. which is included in the group of very strong antioxidants.
FORMULASI LOTION ANTIOKSIDAN EKSTRAK KULIT PISANG KEPOK (Musa balbsiana colla) MENGGUNAKAN EMULGATOR TWEEN 80 DAN SPAN 80 Olii, Audia Triani; Musyid, Mumtihanah; Nurfitriani, Besse
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.272

Abstract

Kepok banana peels contain flavonoid compounds which can be used as antioxidants. Lotion is a type of cosmetic in the emollient (softener) category which has a higher air content. Its functions include maintaining skin moisture, cleaning, preventing moisture loss or retaining active ingredients on the skin. The use of an appropriate combination of emulsifiers between Tween 80 and Span 80 in lotion preparations can form an optimal oil-in-water type emulsion. The aim of this research is to optimize the formulation of kepok banana peel extract lotion (Musa balbisiana colla) with Tween 80 and Span 80 as emulsifiers. The research results showed that the lotion formula was optimized to produce a formula using Tween 80 : Span 80 of 9% : 1%, which had a pH value of 6.4467, viscosity of 12860 cPs, adhesive power of 5.66 seconds, spreadability of 6.4 cm/ seconds, and the antioxidant activity test was 79.9249. Meanwhile, the results of stability testing of the optimum lotion formula showed good stability in homogeneity, pH, spreadability and adhesion tests. However, the viscosity test was unstable.
Review Artikel : PEMANFAATAN KULIT PISANG RAJA (Musa paradisiaca L.) DALAM FORMULASI SEDIAAN KOSMETIK Olii, Audia Triani; Mursyid, Mumtihanah; Shinta, Fitriyah Maya
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.273

Abstract

Plantain peel contains flavonoid compounds that can be used as sunscreen. The purpose of this research is to optimize the preparation of plantain peel extract lotion (Musa paradisiaca L.). The use of Tween 80 and Span 80 in lotion preparations can form a stable in-water oil-type emulsion. The lotion formula is optimized then produces the optimal formula obtained on the use of Tween 80 (6.9%) and Span 80 (3.1%). The optimal formula has a pH of 5.78; viscosity of 20613.33 cPs; adhesion of 4.6 seconds; a spread of 6.23 cm/sec; and determination of an SPF value of 17.262. The optimal formula of the optimization method has insignificant differences. The stability test results of the optimum lotion formula show a stable formula result.
FORMULASI LOTION TABIR SURYA EKSTRAK KULIT PISANG Goroho (Musa acuminafe sp) MENGGUNAKAN KONSENTRASI TWEEN 80 DAN SPAN 80 Olii, Audia Triani; Mursyid, Mumtihanah; Mokodompit, Sukma Meilinda
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.275

Abstract

Flavanoids are compounds that have activity as sunscreen. This compound is contained in banana peels and can be used as sunscreen ingredients. The purpose of this research is to optimize the preparation of goroho banana peel extract lotion (Musa acuminafe sp). The use of certain combinations of Tween 80 and Span 80 in lotion preparations has been reported to be able to form an optimal in-water oil-type emulsion. Formula optimization with various variations of Tween 80 and Span 80 concentrations using Design expert version 10 of the Simplex Lattice Design model with pH parameters, viscosity, adhesion, spreadability and SPF determination. The optimal lotion formula was obtained at the use of Tween 80 4.5% and Span 80 5.5%. The optimal formula has a pH of 5.46, a viscosity of 33226.66 dPas, a adhesion of 6.01 seconds, a spread of 6.25 cm/s, and an SPF test and has good asceptability to respondents. The optimal formula of software prediction results with research results shows insignificant differences. This shows that the Simplex Lattice Design method can be used to predict the physical properties parameters of goroho banana peel extract lotion preparations.
Perbandingan Kadar Perbandingan Kadar Fenolik Ekstrak Daun Karet Kebo (Ficus elastica) Hasil Ekstraksi Bertingkat Menggunakan Metode Spektrofotometri UV-Vis mondo, zhafira anggraini; Suhaenah, Asriani; Tahir, Masdiana
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.278

Abstract

ZHAFIRA ANGGRAINI MONDO. Comparison of Phenolic Content of Rubber Kebo (Ficus elastica) Leaf Extract Results from Multilevel Extraction Using the UV-Vis Spectrophotometry Method (Supervised by Asriani Suhaenah and Masdiana Tahir). The kebo rubber plant (Ficus elastica) is used by Indonesian people as traditional medicine, namely medicine to lower blood pressure, lower cholesterol, stroke, and reduce joint pain. Kebo rubber leaves (Ficus elastica) contain secondary metabolites such as saponins, polyphenols, flavonoids and tannins. This research aims to determine the comparison of phenolic compound levels of kebo rubber leaf extract (Ficus elastica) resulting from multilevel extraction using the UV-vis spectrophotometric method. The extraction process uses 3 different types of solvents, namely n-hexane (nonpolar), ethyl acetate (semipolar) and ethanol (polar) using a sonicator. Determination of phenolic content using the UV-Vis spectrophotometric method, with a maximum wavelength of 772 nm and using gallic acid as a comparison. The results showed that the levels were influenced by the solvent used in comparing the phenolic compound levels of kebo rubber leaf extract (Ficus elastica) with the multilevel extraction method, namely n-hexane extract 3,774 mgGAE/g, ethyl acetate extract 12,696 mgGAE/g, ethanol extract 74,396 mgGAE/g g.
PENENTUAN KADAR TANIN PENENTUAN KADAR TANIN PADA EKSTRAK ETANOL DAUN KARET KEBO (Ficus elastica Roxb. ex Hornem) DENGAN MENGGUNAKAN METODE SPEKTROFOTOMETRI UV-Vis renhoran, aulia azahra; Suhaenah, Asriani; Muflihunna, A.
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.281

Abstract

This research aims to determine the tannin content in the ethanol extract of kebo rubber leaves (Ficus elastica Roxb. ex Hornem). Rubber plants (Ficus elastica Roxb. ex Hornem) are plants that are widely used as traditional medicine, the leaves of this plant are used as medicine to treat diarrhea. , stops bleeding and treats hemorrhoids. Many of the benefits and properties of the kebo rubber plant (Ficus elastica Roxb. ex Hornem) cannot be separated from the compounds contained in it, such as phenolics, tannins, flavonoids and saponins. Simplicia was extracted using the maceration method with 96% concentration of ethanol solvent for 3x24 hours. Determination of tannin content using the UV-Vis spectrophotometric method, with a maximum wavelength of 772 nm, using gallic acid as a comparison. The research results showed that the total tannin content in the ethanol extract was an average of 31.708mgQE/g.
Comparasion Of Levels Perbandingan Kadar Flavonoid Ekstrak Daun Karet Kebo (Ficus elastica)Hasil Ekstraksi Bertingkat Menggunaka evatiara, nur; Suhaenah, Asriani; Tahir, Masdiana
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.282

Abstract

NUR EVATIARA. Comparison of flavonoid levels of rubber plant leaf extract (Ficus elastica) resulting from multilevel extraction using the UV-Vis spectrophotometric method. (Supervised by Asriani Suhaenah and Masdiana Tahir). Rubber plant (Ficus elastica) is a plant in the Moraceae family whose leaves have been empirically stated to contain secondary metabolite compounds such as saponins, polyphenols, flavonoids and tannins which have been used as medicine for coughing up blood, improving urine flow, relieving pain and improving blood circulation. The aim of this research was to determine the comparison of levels of flavonoid compounds in rubber plant leaf extract (Ficus elastica) resulting from multilevel extraction using the UV-Vis spectrophotometric method. The multistage extraction process uses 3 different types of solvents, namely n-hexane (nonpolar), ethyl acetate (semipolar), and ethanol (polar) using a sonicator. Determination of flavonoid levels using the UV-Vis spectrophotometric method, with a maximum wavelength of 432 nm and quarcetin as a comparison. The research results were influenced by the solvent used in comparing the levels of flavonoid compounds, namely rubber plant leaf extract (Ficus elastica) with a multilevel extraction method, namely N-hexane extract 7.161 mgQE/g, Ethyl acetate extract 7.663 mgQE/g, 96% Ethanol extract 10.592 mgQE/g g.
antioxidant activity Uji aktivitas antioksidan ekstrak daun karet kebo (Ficus elastica) dengan menggunakan metode maserasi bertingkat Yani, Indah Ahmad; Suhaenah, Asriani; Aminah, Aminah
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.283

Abstract

Kebo rubber (Ficus elastica) is one type of plant in Indonesia as a medicine to lower blood pressure, reduce cholesterol, stroke and reduce joint pain. In addition, Kebo rubber (Ficus elastica) leaves are one of the ficus species that are thought to be rich in polyphenolic compounds so that they can act as antioxidants. Antioxidants are compounds that can be used to counteract free radicals. Food fiber and antioxidants are two types of components that are very beneficial in improving health and being able to prevent various diseases. This study aims to analyze the antioxidant activity of rubber kebo (Ficus elastica) leaf extract using the DPPH method. The maceration process uses 3 different types of solvent, namely n-hexane (non-polae), ethyl acetate was measured at 510 nm wavelength with quercetin as the standard comparator. The measurement result for n-hexan extract obtained IC50 of 531,90 µg/mL, ethyl acetat obtained IC50 of 188,06 µg/mL, and for ethanol extract obtained IC50 of 874,73 µg/mL.
PROFIL PENYIMPANAN OBAT Profile penyimpanan obat di Puskesmas wosu Kabupaten Morowali David, Moh; Nurlina, Nurlina; Zulkarnain, Iskandar
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.284

Abstract

Drug storage profiles are an importand factor ini drug management at community health center, because with proper storage of medicines it will be easier and more effective to guarantee the quality of medicines. This research aims to determine the procedures for regulating drugs and improving the quality of drug storage at the wosu healty center, bungku barat sub-district, morowali district. Data collection was carried out through interviews and using observation sheets regarding aspects of drug storage in community health centers including general aspects, special aspectsinclude requirements for drug storage warehouses with 15 aspects assesed with a persentage of 100%, special aspects include requirements of drug preparation with 5 aspects assessed with a percentage of 100% and document review includes procedures for recording drugs. From the result of research in the field there are still several problems that do not meet standards. How ever in general the results of this study show that drug storage, preparation of drugs, and recording of drugs at the wosu comunity health center, bungku barat sub- district, morowali regency are in the good category.
Antioxidant activity Antioxidant activity of ethanol extract of bitti leaves (Vitex cofassus Reinw. ex. Blume) using the dpph free radical scavenging method Bahari, Dita Wulan; Suhaenah, Asriani; Muflihunna, A.
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 3 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i3.288

Abstract

Antioxidants are compounds that can counteract free radicals in the body, reduce oxidation in cells and cell damage. The purpose of this study was to determine the antioxidant activity of ethanol extract of bitti leaves (Vitex cofassus Reinw. Ex. Blume with DPPH (2,2- diphenyl-1-picrylhydrazyl) scavenging method. The absorbance was measured by UV-Vis spectrophotometer at 510 nm wavelength. The results showed the presence of antioxidant activity with IC50 value of 56.59 μg/mL with strong antioxidant activity category, while quercetin as a comparator has very strong antioxidant activity with IC50 value of 5.93 μg/mL.

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