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INDONESIA
Indonesian Journal Health Science and Medicine
Published by Universitas Muhammadiyah Sidoarjo
ISSN : -     EISSN : 30638186     DOI : https://doi.org/10.21070/ijhsm
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health Veterinary
Focus: The Indonesian Journal on Health Science and Medicine (IJHSM) focus to advance the field of health science and medicine by publishing high-quality, peer-reviewed research articles, reviews, and case studies. Our journal serves as a platform for researchers, clinicians, and healthcare professionals to share innovative findings, critical insights, and emerging trends in the broad domain of health science and medicine. Scope: Clinical Research and Practice Studies on the diagnosis, treatment, and prevention of diseases. Clinical trials and evidence-based practices. Advances in medical technology and therapeutics. Public Health Epidemiology and health statistics. Health policy and management. Community health initiatives and health education. Biomedical Science Research on cellular and molecular biology. Genetics and genomics. Pharmacology and toxicology. Health Care Systems and Services Health care delivery and management. Quality improvement in health care services. Health economics and health informatics. Global Health Health issues affecting populations worldwide. International health regulations and practices. Global health governance and diplomacy. Health Promotion and Disease Prevention Lifestyle and behavioral interventions. Preventive medicine and early detection. Nutritional science and physical activity. Mental Health Research on mental health disorders and treatments. Psychological well-being and mental health promotion. Integration of mental health services in primary care. Innovations in Health Education and Training Medical and health science education methodologies. Training programs for health professionals. Continuing education and professional development.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 87 Documents
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Search results for , issue "Vol. 2 No. 1 (2025): July" : 87 Documents clear
Undergraduate Nursing Students' Knowledge and Attitudes Towards Dementia: A Cross-Sectional Study in Iraq: Pengetahuan dan Sikap Mahasiswa Keperawatan terhadap Demensia: Sebuah Studi Cross-Sectional di Irak Hammooz, Asmaa
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i2.129

Abstract

Background: A reduction in cognitive function, or the ability to think, is typically the outcome of dementia, a disorder that can be caused by a number of diseases that progressively harm the brain and break down nerve cells. Objectives: to evaluate the student's knowledge and attitude regarding dementia and to determine the connection between students' demographic traits and their knowledge and attitude. Methods: Undergraduate nursing students participated in a descriptive cross-sectional study. Nonprobability purposive sampling was chosen for (264) students in the College of Nursing University of al-Qadisiyah. In order to engage in the study, the researcher uses an instrument that is divided into three parts: part one is a demographic data form; part two includes information about dementia form includes (30) items, and part three is attitude toward dementia form (9) items. Results: According to the study's findings, students' overall knowledge rating was fair, with a mean score of 0.58. Conclusion: As the student progresses through the academic stages, their knowledge increases and this knowledge is reflected in their attitudes towards dementia, the study showed that the knowledge of the student in the fourth class with, and in the attitudes. Highlights: Dementia reduces cognitive function due to brain cell damage. Assess nursing students’ dementia knowledge, attitude, and demographic influence. Cross-sectional study of 264 students using structured questionnaires. Keywords: Undergraduate Nursing student, dementia, knowledge, attitude.
A Review on the Relationship Between p53 Gene and Viruses in Endometriosis: Tinjauan tentang Hubungan Antara Gen p53 dan Virus pada Endometriosis Khzal, Alaa Mahdy Obaid
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i1.130

Abstract

Ten percent of pre-menopausal women suffer from endometriosis which manifests as a chronic inflammatory disorder due to complicated and poorly understood pathogenesis. The relationship between P53 tumor suppressor genes and viral infections as causes of endometriosis needs complete evaluation in research. Studies conducted at the molecular level reveal endometriotic lesions display major P53 expression variations while functional regulation and defensive abilities change from somatic mutations and DNA polymorphisms in addition to epigenetic influences that block tumor-suppression operations. Multiple investigations have established that endometriotic tissues carry human papillomavirus (HPV) Epstein-Barr virus (EBV) and cytomegalovirus (HCMV) viral DNA sequences with varying frequency percentages. The proposed mechanisms study how viral oncoproteins activate P53 pathways in endometriosis development by damaging cell death systems and through their influence on inflammatory processes and genomic instability creation and cell motility changes. The review examines how such biological interactions impact endometriosis diagnosis and treatment options. Currently missing components of known analysis become apparent in this research as it points out needed study techniques for understanding the sophisticated relationship between sun-induced skin damage and Human Papillomavirus infections. Highlights: Endometriosis involves disrupted P53 function due to mutations, polymorphisms, and epigenetics. Viral DNA from HPV, EBV, and HCMV is found in endometriotic tissues, implicating infections in disease progression. Viral oncoproteins may alter P53 pathways, affecting inflammation, cell death, and genomic stability. Keywords: Endometriosis, P53 Tumor Suppressor, Human Papillomavirus, Viral Oncoproteins, Inflammation
Factors Influencing Antenatal Care Services Utilization in Primary Health Care Centers in the Second Sector of Basra City Center: Faktor-faktor yang Mempengaruhi Pemanfaatan Pelayanan Antenatal Care di Puskesmas di Sektor Kedua Pusat Kota Basra Hasan, Marwa Abdul-Satar; Abdul-Qader, Rasha Ahmed; Obaid, Hanadi Lazim
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i1.131

Abstract

This cross-sectional study was conducted to assess the factors influencing the utilization of ANC services. The total sample consisted of 400 cases with a previous history of pregnancy attending ANC for less than one year, was collected from 15 PHCCs in the second sector of Basra city center, through face-to-face interviews and the use of a questionnaire format during the study period which extended from the beginning of February to the end of July 2018. The results of the present study showed that (31.5%) of the participants’ ages were between 20-25 years old. About two-thirds of the studied women (68.5%) lived in the family home of their husbands; (69.0%) of them had a partner of 1–3. Both studied women, and their husbands had the highest percentage of intermediate education, (28.5%) and (29.5%) respectively. The majority of women (93.7%) were housewives, and most of their husbands were self-employed (67.3%). The highest percentage of participants (66.0%) lived in families composed of seven and above members. There were (89.5%) of women had no history of stillbirth. It was suggested that more government efforts be made to target less educated women and to inform them of the advantages of using antenatal care, this proposal also needs to include their husbands and improve family planning services. Government policy should help increase the spread of the media among mothers. Provide ultrasonic examination services (SONAR) in all primary health care centers and finally, further research should be obtained to include both urban and rural areas. Highlights: Majority were housewives, aged 20–25, with intermediate education level. Most lived in large families, husband's home, with 1–3 children. Recommend education, media access, SONAR services, and broader research coverage. Keywords: Factors, Antenatal Care Services, in Primary Health Care Centers.
Relationship Between Pitx2 Snps with Weights and Body Measurements in Goat: Hubungan Antara Pitx2 Snps dengan Bobot dan Ukuran Tubuh pada Kambing Al-Rubaye, Shaimaa G. A.; Al-Zubaidi , Zainab Hussein Kareem; Redha , Huda Muhanna Redha; Kalaf, Ali Ahmed
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i1.132

Abstract

This study was conducted at the Ruminant Research Station, affiliated with the Ministry of Agriculture, from December 1, 2021, to March 5, 2022. The objective was to investigate the relationship between single nucleotide polymorphisms (SNPs) in the Paired-like homeodomain transcription factor A (PITX1) gene and growth traits, including body measurements, in goats. A total of 52 female goats were used, including 16 native and 36 Shami goats. DNA sequencing of a 966 bp fragment from the promoter region of the PITX1 gene revealed four mutations. The SNPs G1198A and G1089A exhibited two genotypes: wild-type GG and heterozygous GA, with the mutant homozygous genotype AA not detected. For the C1194T SNP (referred to in the original text as ClYIT), three genotypes were identified: CC (wild), CT (heterozygous), and TT (mutant). Another SNP, G1003A, presented all three genotypes: GG, GA, and AA. The results showed that birth weight and body measurements, such as heart girth and body length, were significantly affected by the C1194T mutation and varied among genotypes. Most other growth traits, however, were not significantly influenced by breed differences. In detail, the highest dam birth weight was observed in the CC genotype (3.23 kg), while the CT genotype was associated with lower neonate birth weight (3.19 kg). The TT genotype (mutant) recorded the highest values for heart girth (83.4 cm) and body length (79.45 cm) in neonates. Furthermore, the G1003A mutation significantly increased dam birth weight, reaching 3.55 kg in individuals with the mutant AA genotype, although it had no significant effect on other growth traits or body dimensions. Highlights: PITX1 SNPs identified: Four mutations were found in the promoter region, notably C1194T and G1003A. Growth traits affected: C1194T and G1003A SNPs significantly influenced birth weight and body measurements. Genotype impact varies: TT and AA genotypes showed superior values in specific growth traits. Keywords: Pitx2, Goat, Snps, Growth, Traits
Why Cancer Cells Crave Sugar: A Review: Mengapa Sel Kanker Sangat Membutuhkan Gula: Sebuah Ulasan Sadiq, Dina H.
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i1.139

Abstract

In addition to causing weight gain, eating too much sugar raises the risk of obesity and diabetes, both of which raise the chance of cancer. It turns out that while eating sugar does not always cause cancer, it can cause the disease because of the way it affects your waist. Sugar is necessary for cancer cells to survive, not to proliferate and divide. Although this sugar is absorbed by all bodily tissues, it is more readily absorbed by tissues with higher energy requirements, such as cancer cells. Because of this, some people have concluded that sugar accelerates the growth of cancer cells. "I'd be shocked if cutting back on sugar didn't help lower the risk of cancer," she says. "High-fructose corn syrup, which is found in soft drinks, sweetened teas, sports drinks, and processed meals, as well as in candy, cookies, ice cream, and sweetened breakfast cereal, should be avoided. Highlights: Excess sugar raises obesity and diabetes risk, increasing cancer risk. Cancer cells absorb more sugar due to higher energy needs. Avoid high-fructose corn syrup in processed and sugary foods. Keywords: cancer, cells, crave, sugar
Biochemistry of Sleep Quality and Daytime Sleepiness for Employees and University Students: Biokimia Kualitas Tidur dan Rasa Kantuk di Siang Hari untuk Karyawan dan Mahasiswa Yunus, Tadamoun Sabah
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i1.140

Abstract

Background: In the brain, neurotransmitters and hormones interact intricately to control sleep. While adenosine builds up over time to cause tiredness, neurotransmitters like serotonin and norepinephrine encourage wakefulness. Objectives: Measuring the impact of a lack of sleep on daytime sleepiness and daily performance and identifying factors affecting sleep, such as psychological stress, working hours, and daily habits. Methods: This study employs a descriptive, analytical, cross-sectional design. To measure daytime sleepiness and sleep quality, 150 college students were given a self-administered questionnaire. Data on sleep habits and their relationships can be gathered at a single point in time according to the study's cross-sectional design. Descriptive and inferential statistics were utilized to examine the replies, and convenience sampling was employed. Results: Based on the overall statistical results, which include the descriptive statistics for the mean score of 1.52 and a standard deviation of 0.175, the final assessment of sleep quality for individuals is classified as "Bad" This indicates that the majority of participants are experiencing poor sleep quality, as reflected by the mean score falling within the "Bad" range. Conclusion: This indicates that the majority of participants are experiencing poor sleep quality, as reflected by the mean score falling within the Bad range. Highlights: Neurotransmitters and hormones regulate sleep and wakefulness in the brain. Cross-sectional survey of 150 students using descriptive, inferential statistics. Most participants showed poor sleep quality with high daytime sleepiness. Keywords: Biochemistry, Sleep Quality, Daytime Sleepiness, Employees, University Students
The Effect of Some Nanoparticles on The Growth of Multi-Resistant Escherichia Coli Bacteria Isolated From Different Sources in Diyala University: Pengaruh Beberapa Nanopartikel Terhadap Pertumbuhan Bakteri Escherichia Coli Multi Resisten yang Diisolasi dari Sumber yang Berbeda di Universitas Diyala Al-Dulaimi, Ibrahim. M.; Nuaimi , Ahmed .I. Al; hasan, Mohammed .A.
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i1.141

Abstract

Background: Escherichia coli bacteria possess a number of virulence factors, in addition to their ability to acquire enterotoxin genes through plasmids or bacteriophages, or through genes acquired from other pathogenic bacterial genera through bacterial conjugation. The resistance to antibiotics that bacteria possess is considered one of the most important economic and health problems around the world. Nanoparticles are mainly used in antibacterial applications due to their long-term stability and biocompatibility. The mechanisms behind the antimicrobial effect of these nanoparticles are metal ion release, oxidative stress, and non-oxidative stress that occur simultaneously. Mineral nanoparticles are characterized by their broad-spectrum properties against both Gram-negative and Gram positive bacteria. Objectives: The study aimed to determine the effect of nanomaterials on the growth of E. coli bacteria Methods: Been collected of 100 samples collected from urinary tract infections and stool in Sterile bottles in different hospitals in Baquba city (Baquba Teaching Hospital and Al- Batool Hospital) It was subjected to detecting the resistance of the isolates to six antibiotics and the extent of the effect of nanomaterials on bacterial growth Results: Thirty-three isolates of E. coli bacteria were obtained. From urine and stool, the isolates were tested for resistance to six antibiotics: Amoxicillin-Clavulanic acid, Cefotaxime, Cefepime, Ciprofloxacin, Ampicillin, and Tetracycline. The effect of nanomaterials, silver and zinc nanoparticles, on bacterial growth was determined, as the results showed a decrease in bacterial growth as a result of the use of nanomaterials. Conclusion: Escherichia coli isolates are characterized by their multiple resistance to antibiotics, which increases their pathogenicity. The use of nanoparticle inhibitors of silver and zinc led to a decrease in bacterial growth, which makes them used as alternatives in treatment. Highlights: coli shows virulence, gene transfer, and antibiotic resistance. Evaluate nanomaterials' effect on E. coli bacterial growth. Silver, zinc nanoparticles reduce E. coli growth; potential antibiotic alternatives. Keywords: Escherichia coli. Nanoparticles; urinary tract infection; Antibiotic resistance
Society's Knowledge About Physiological Causes of Hair Loss: A Cross-Sectional Study at The University of Basrah: Pengetahuan Masyarakat Tentang Penyebab Fisiologis Kerontokan Rambut: Sebuah Studi Cross-Sectional di Universitas Basrah Al-Hejaj, Zahraa Mahmoud Hussain
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i1.143

Abstract

Background: About 50% of men and nearly 50% of women experience hair loss, making it one of the most prevalent aesthetic issues in the world. This condition can have a detrimental impact on each person's quality of life and can result in circumstances that can cause psychological distress and demoralization. It's critical to comprehend whether hair loss is a regular physiological process or whether it's an aberrant process brought on by issues with the scalp or its bulb, for example. Since baldness, alopecia, and all forms of hair loss are always the consequence of multiple factors that contribute to their development, defining them is frequently difficult and reductive. Objectives: To assess the knowledge about the physiological reasons that lead to hair loss and find the relationship between knowledge and socio-demographic characteristics. Material and methods: A descriptive cross-sectional study was conducted from October 10, 2024, to January 15, 2025. A random sample of 150 people from Basrah University participated in the study. To gather information and evaluate knowledge, a questionnaire was employed. Results: Most of the university population is not sure that Cushing's syndrome does not cause hair loss (44.7%), most of the university population agree Hyperthyroidism causes hair loss (76.7%), most of the university population agree Vitamin D deficiency causes hair loss (89.3%), The majority of university students concur that there is a connection between ferritin insufficiency and hair loss (40.7%), while the majority of students concur that there is a connection between zinc deficiency and hair loss (71.3%). However, half of the students disagree. The majority of university students believe that iron deficiency and hair loss are related (84.7%), that obesity causes hair loss (50%), and that heredity does not cause hair loss (76.7%). Additionally, the majority of university students (70%) concur that there is a connection between vitamin A insufficiency and hair loss, and over half (55.3%) concur that there is a connection between biotin shortage and hair loss, more than half of college students (57.3%) concur that folic acid deficiency and hair loss are related. Conclusion: According to the results of this study, most university students are well-informed about hair loss. Highlights: air loss affects 50% of men and women, impacting quality of life. Objectives: Assess knowledge on physiological causes of hair loss and socio-demographics. Conclusion: Most university students are well-informed about hair loss causes. Keywords: Society, Physiological, Hair loss, Vitamin D, knowledge
The Effect of Taxol on some Blood Parameters and Study of Histopathological Changes in the Kidneys of Laboratory Rats: Pengaruh Taxol terhadap beberapa Parameter Darah dan Studi Perubahan Histopatologi pada Ginjal Tikus Laboratorium Hammood, Zahraa Y.; Rashid, Alaa R.
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i1.144

Abstract

Taxol is a microtubule inhibitor drug widely used in treatment of many types of cancer. In the present study Taxol at different doses if the rats were randomly divided into three groups, each group containing 12 laboratory rats, as follows: The control group consisted of 12 rats injected with 0.5 ml of distilled water. The low dose group consisted of 12 rats injected with 2 mg/kg of Taxol intraperitoneally. The high dose group consisted of 12 rats injected with 4 mg/kg of Taxol intraperitoneally. The results of histological examination of tissue sections showed pathological histological changes in the kidneys of laboratory rats. The results of the current study showed a significant decrease below the probability level of P≤0.05 in blood parameters including white blood cell count and percentage of lymphocytes, neutrophils, eosinophils and basophils in laboratory rats treated with (TAXOL) at two doses (2.4 mg/kg). The results of the study showed a significant decrease in the number of red blood cells below the probability level of P≤0.05 at both high and low doses, noting that the effect of the high dose was greater than the low dose. The results of histological sections of the kidneys of laboratory rats treated with Taxol showed blood congestion in the blood vessels with degenerations in the proximal and distal endothelial cells and atrophy of the renal glomeruli Highlights: Groups: Control, 2 mg/kg Taxol, 4 mg/kg Taxol (n=12/group). Blood: Taxol reduced WBC, RBC, lymphocytes, neutrophils significantly (P≤0.05). Kidney: Congestion, cell degeneration, glomerular atrophy observed in treated rats. Keywords: Taxol, Chemotherapy, nephrotoxicity, Hematological
Cisplatin-induced Genotoxicity and Protective Effect of Aqueous Ginkgo Biloba Extract in an Animal Model: Genotoksisitas yang Diinduksi Cisplatin dan Efek Perlindungan Ekstrak Ginkgo Biloba Berair dalam Model Hewan Al-Safi, Mushtaq Talib
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i1.145

Abstract

It has recently been proven that many natural compounds made from crude plant extracts offer protection from the passive effects of various contaminants. One common spice and therapeutic herb is Gingko Biloba Extract. To study the effect of aqueous Gingko Biloba Extract in inhibiting the genotoxicity of cisplatin, we gave the first group cisplatin 10mg/kg only. During the work, the second group was treated with an aqueous extract of Gingko Biloba Extract 50mg/kg then 10mg/kg cisplatin. The third group was treated with an aqueous extract of Gingko Biloba Extract 100mg/kg then cisplatin 10mg/kg. On the other hand, the last group was treated with the same aqueous extract 150mg/kg, then 10mg/kg cisplatin. To perform genetic tests, we used micronuclei and sperm abnormality tests. After the treatment with cisplatin, the micronuclei and sperm abnormality were induced; however, the treatment with aqueous extract of Gingko Biloba Extract, the micronuclei and sperm abnormality were significantly reduced in male mice. These results demonstrated that cisplatin treatment alone is not effective as cisplatin treatment in combination with aqueous extract of Gingko Biloba Extract in reducing the amount of sperm head abnormalities and micronucleus. Highlights: Groups: Cisplatin alone; Ginkgo 50, 100, 150 mg/kg + cisplatin. Tests: Micronucleus and sperm abnormality tests performed on male mice. Result: Ginkgo reduced cisplatin-induced micronuclei, sperm abnormalities significantly. Keywords: Crocus sativus, Cisplatin, Sperm head abnormalities, Micronucleus Tests

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