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Contact Name
Azis Ikhsanudin
Contact Email
azis.ikhsanudin@pharm.uad.ac.id
Phone
+6289506685859
Journal Mail Official
clips@uad.ac.id
Editorial Address
Faculty of Pharmacy, Kampus 3 UAD, Jalan Prof. Dr. Soepomo, S.H. Janturan Yogyakarta, INDONESIA 55164
Location
Kota yogyakarta,
Daerah istimewa yogyakarta
INDONESIA
Clinical and Pharmaceutical Sciences Journal
ISSN : -     EISSN : 30895669     DOI : https://doi.org/10.12928/clips.v1i1.307
Core Subject : Health, Science,
Clinical and Pharmaceutical Sciences (CliPs) Journal utilizes contributions from academics and practitioner-researchers on Clinical dan Pharmaceutical Sciences. Clinical and Pharmaceutical Sciences Journal is a periodical scientific journal published by Universitas Ahmad Dahlan, Indonesia. The journal encourages interdisciplinary discussions and interactions in various topics related to health and pharmaceutical sciences, within or across disciplines. Clinical and Pharmaceutical Sciences Journal accepts scientific papers in the form of research reports (original article research papers), systematic review, and meta analysis with focus and scope: pharmaceutical technology, pharmacology and toxicology, pharmaceutical chemistry, pharmaceutical biology, clinical and community pharmacy, pharmacoeconomy, pharmacoepidemiology, pharmaceutical care, management of pharmacy, biopharmaceutics, pharmaceutical microbiology and biotechnology, pharmacokinetics, alternative medicines, cosmetic technology, health policy, medicine (miscellaneous), public health, environmental and occupational health, and nursing. This journal provides an innovative platform for researchers, students, practitioners, and educators to learn and contribute to this field. All articles must undergo initial Editorial screening and then undergo a rigorous double-blind peer review process before publication. Open Access Journal: All of the published manuscripts can be accessed online. Rapid Publication: After finishing the review process, revision, and editing, the accepted paper will be published online soon. Editor, reviewer, and author from the International Forum. The published article has a permanent page and Digital Object Identifier (DOI), making it easy to index many databases.
Articles 31 Documents
Inhibition Strength of Free Radicals of DPPH and Staphylococcus aureus by Ethanol Extract of Papaya Leaves (Carica papaya L) mustofa Ahda; Aisah Erna Wanti; Rizki Dwi Mantoro; Iin Narwanti; Norsyafikah Asyilla Nordin
Clinical and Pharmaceutical Sciences Journal Vol. 2 No. 3 (2026)
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/vp78ec88

Abstract

Papaya (Carica papaya L.) leaves are a significant source of bioactive compounds that warrant scientific attention. This study conclusively evaluates the potency of papaya leaf extract as a valuable herbal ingredient for pharmaceutical applications. Papaya leaves were extracted by maceration using 70% and 96% ethanol for 24 h. Our investigation examined the antioxidant activity of the papaya leaf extract using the DPPH radical scavenging assay, alongside an analysis of its antibacterial properties against Staphylococcus aureus. The results revealed that the TPC of the 70% ethanol extract is remarkably higher at 65.27 ± 1.21% compared to only 12.64 ± 0.27% for the 96% ethanol extract. This significant discrepancy in phenolic content directly correlates with the variations observed in antioxidant and antibacterial activities. Although both extracts exhibited a low capacity to scavenge DPPH free radicals, the inhibition zones against S. aureus were measured at 1.47 ± 0.05 mm for the 70% ethanol extract and 1.37 ± 0.05 mm for the 96% ethanol extract (at a concentration of 8 mg/mL), clearly indicating their limited antibacterial efficacy under the tested conditions. These findings underscore the crucial influence of ethanol concentration on the total phenolic content of papaya leaf extracts. While the antioxidant and antibacterial activities remain limited, the data presented here provide essential insights that pave the way for future research into the phytochemical properties and potential applications of papaya leaf extracts.

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