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Azis Ikhsanudin
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Faculty of Pharmacy, Kampus 3 UAD, Jalan Prof. Dr. Soepomo, S.H. Janturan Yogyakarta, INDONESIA 55164
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Clinical and Pharmaceutical Sciences Journal
Published by Universitas Ahmad Dahlan
ISSN : -     EISSN : 30895669     DOI : https://doi.org/10.12928/clips.v1i1.307
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Materials Science & Nanotechnology Medicine & Pharmacology
Clinical and Pharmaceutical Sciences (CliPs) Journal utilizes contributions from academics and practitioner-researchers on Clinical dan Pharmaceutical Sciences. Clinical and Pharmaceutical Sciences Journal is a periodical scientific journal published by Universitas Ahmad Dahlan, Indonesia. The journal encourages interdisciplinary discussions and interactions in various topics related to health and pharmaceutical sciences, within or across disciplines. Clinical and Pharmaceutical Sciences Journal accepts scientific papers in the form of research reports (original article research papers), systematic review, and meta analysis with focus and scope: pharmaceutical technology, pharmacology and toxicology, pharmaceutical chemistry, pharmaceutical biology, clinical and community pharmacy, pharmacoeconomy, pharmacoepidemiology, pharmaceutical care, management of pharmacy, biopharmaceutics, pharmaceutical microbiology and biotechnology, pharmacokinetics, alternative medicines, cosmetic technology, health policy, medicine (miscellaneous), public health, environmental and occupational health, and nursing. This journal provides an innovative platform for researchers, students, practitioners, and educators to learn and contribute to this field. All articles must undergo initial Editorial screening and then undergo a rigorous double-blind peer review process before publication. Open Access Journal: All of the published manuscripts can be accessed online. Rapid Publication: After finishing the review process, revision, and editing, the accepted paper will be published online soon. Editor, reviewer, and author from the International Forum. The published article has a permanent page and Digital Object Identifier (DOI), making it easy to index many databases.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 14 Documents
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The Effect of Titanium Dioxide and Porang Starch (Amorphophallus oncophyllus) Combination on the SPF Value and Physical Properties of Sunscreen Lotion Formulation Fauzia, Afifah Hasna; Vanda Pertiwi, Deasy; Saputri, Asti Rizki; Khoirunnisa, Afifah; Bestari, Angi Nadya
Clinical and Pharmaceutical Sciences Journal Vol. 1 No. 3 (2025)
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/clips.v1i3.381

Abstract

Optimization of Dispersible Diclofenac Potassium Tablet Formula with a Combination of Explotab and Avicel PH-101 Kurniawan, Dhadhang; Andiani, Nauli Marsha; Utami, Vitis Vini Fera Ratna
Clinical and Pharmaceutical Sciences Journal Vol. 1 No. 3 (2025)
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/clips.v1i3.382

Abstract

Diclofenac potassium is a nonsteroidal anti-inflammatory drug (NSAID) frequently employed as an analgesic therapy for inflammatory conditions and pain associated with Osteoarthritis and Rheumatoid Arthritis. It is formulated as a dispersible tablet, requiring dispersion in solution prior to administration to expedite onset and facilitate use, particularly for patients with difficulty swallowing intact tablets. This study aims to investigate the effects of the optimal combination and proportion of Explotab and Avicel pH-101 in the formulation of diclofenac potassium dispersible tablets using the Simplex Lattice Design (SLD) method with two factors. The tablet formulations, based on the SLD method with Explotab (A) and Avicel pH-101 (B) as excipients, are as follows: FI (100% A), FII (75% A:25% B), FIII (50% A:50% B), FIV (25% A:75% B), and FV (100% B). The tablets were prepared via direct compression and subsequently evaluated for their physical properties, including hardness, friability, size uniformity, weight uniformity, disintegration time, dispersion time, wetting time, and content determination. The study's findings indicated that the combination of Explotab and Avicel pH-101 affected the physical properties of the tablets, notably decreasing weight uniformity, enhancing tablet hardness, reducing friability, and prolonging both disintegration and dispersion times of the diclofenac potassium dispersible tablets. The optimal formula was identified as comprising 40% Explotab and 60% Avicel pH-101. This optimal formulation was determined based on the highest total response value calculated using the Simplex Lattice Design with two factors
The Effect of Turmeric Simplicia’s (Curcuma longa L.) Washing Treatment on Total Ash, Total Plate Count, Yeast and Mold Count and Curcumin Level Harnanda Putri, Margaretha; Kawiyanto, Joko; Hartati, Puji; Nurraudah, Siti; Ahmad, Nazir
Clinical and Pharmaceutical Sciences Journal Vol. 1 No. 3 (2025)
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/clips.v1i3.472

Abstract

Turmeric (Curcuma longa L.) is one of the traditional plants of Indonesia that has antibacterial activity, helps reduce fever, osteoarthritis, and digestive disorders. The washing process of simplicia is one of the sorting processes in post-harvest handling. This study aims to obtain the best washing method for simplicia with several washing treatments against the total ash content, Total Plate Count (TPC), Yeast and Mold Count (YMC), and curcumin content in turmeric simplicia and turmeric extracts. The study was conducted experimentally with 6 variations of simplicia washing treatments, namely without washing, washing with running water, washing with water at 50°C, washing with 0.2% NaOH, washing with 0.05% HCl, and washing with 2.0% acetic acid. The results showed that washing with 2.0% acetic acid produced the lowest total ash content of the extract at 1.87%. Washing with 50°C water provided the lowest TPC value test data of 6.7 CFU/g, washing with 50ºC water provided the highest curcumin content test data of 9.38%. Based on several parameters of the test results, the washing process chosen was washing the simplicia using 50ºC water which showed high curcumin levels, TPC and YMC values that met the requirements, as well as the ease and safety of the washing method.
A Review of Ethnopharmacological Practices Among Two Indigenous Communities In Sumatra: The Anak Dalam And Mentawai Tribes Anasri, Fadhil Mubarak; Syafri, Suryati
Clinical and Pharmaceutical Sciences Journal Vol. 1 No. 3 (2025)
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/clips.v1i3.478

Abstract

Indonesia is a country rich in biodiversity and high culture, including traditional knowledge such as the use of medicinal plants. This study examines ethnopharmacological practices in two indigenous communities on the island of Sumatra: the Anak Dalam tribe in Jambi and the Mentawai tribe in West Sumatra. The study reviewed several articles on medicinal plants on Google Scholar related to the plant species used, plant parts utilized, processing methods, and indications for their use in traditional medicine. The review results show that both tribes utilize various plants to treat ailments such as fever, diarrhea, coughs, wounds, digestive disorders, and infections. Some of these are supported by scientific evidence regarding their pharmacological activities, such as Zingiber officinale, Psidium guajava, Curcuma longa, and Eurycoma longifolia. The results of this review confirm that the traditional knowledge of both communities has excellent potential for development in pharmacy and conventional medicine. Documentation and scientific study of medicinal plants are crucial for cultural preservation and the development of traditional medicine.

Page 2 of 2 | Total Record : 14

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