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Achmad Firdaus Sani
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Journal of Neurointervention and Stroke (JNeViS)
Published by Perhimpunan Dokter Spesialis Neurologi Indonesia
ISSN : -     EISSN : 31236227     DOI : https://doi.org/10.63937/jnevis-2025.12.12
Core Subject : Health, Science,
Medicine & Pharmacology Neuroscience
Journal of Neurointervention and Stroke (JNeViS) is a peer-reviewed journal dedicated to publishing clinical, epidemiological, basic science, and translational research in vascular and interventional neurology. The journal also welcomes contributions on other neurological and neurosurgical conditions that may benefit from minimally invasive and innovative approaches across specialties such as Neurology, Radiology, and Neurosurgery. Suitable submissions for this Journal include Original Article (observational studies, clinical trials, epidemiological research, health services and outcomes studies, basic and translational research, and innovative techniques in vascular and interventional neurology), and Case Reports or Case Series.
Arjuna Subject : Kedokteran - Neurologi Klinis
Articles 15 Documents
 1   2 
Funduscopic and Transcranial Doppler Profile of the Ophthalmic Artery in Stroke Patients with Hypertensive Retinopathy Dini Adriani; Eva Dewati; Freddy Sitorus; Ni Nengah Rida Ariani; Dinda Diafiri; Tiara Kasih; Mohammad Kurniawan
Journal of Neurointervention and Stroke Vol. 1 No. 2: NOVEMBER 2025
Publisher : Neurointervention Working Group of Indonesian Neurological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63937/jnevis-2025.12.12

Abstract

Highlight: Hypertensive retinopathy may predict stroke risk TCD may complement funduscopy in stroke with HR ABSTRACT Introduction: Hypertensive retinopathy (HR) is a manifestation of chronic vascular damage and is increasingly recognized as a predictor of stroke. Funduscopy and Transcranial Doppler (TCD) examination of the ophthalmic artery may offer non-invasive insight into cerebrovascular health. Objective: To describe the demographic, funduscopic, and ophthalmic artery hemodynamic profiles in stroke patients with hypertensive retinopathy using Transcranial Doppler. Method: A cross-sectional descriptive study was conducted from May 2022 to May 2025 at Cipto Mangunkusumo National Hospital, involving 67 ischemic stroke patients with HR. Retrospective data were collected from medical records, including sociodemographics, fundus classification based on Wong and Mitchell, and Pulsatility Index (PI) values of the ophthalmic artery from TCD. Result: Mild hypertensive retinopathy is prevalent in ischemic stroke patients, and elevated ophthalmic artery PI values are suggestive of small-vessel disease. Conclusion: Funduscopy and TCD can be complementary tools in evaluating stroke risk in hypertensive.
Profile of Acute Ischemic Stroke Patients Receiving Intravenous Thrombolysis with Recombinant Tissue Plasminogen Activator at Soeradji Tirtonegoro Hospital Adika Mianoki; Fatikha Fajar Wiati; Hanum Salsabila
Journal of Neurointervention and Stroke Vol. 1 No. 2: NOVEMBER 2025
Publisher : Neurointervention Working Group of Indonesian Neurological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63937/jnevis-2025.12.13

Abstract

Highlight: Most patients showed early neurological improvements after IV thrombolysis The door-to-needle time was  longer than the recommended guidelines A patient profile may guide the optimization of stroke management ABSTRACT Introduction: Acute ischemic stroke is a leading cause of mortality and disability worldwide, including in Indonesia. Intravenous thrombolysis with recombinant tissue plasminogen activator (rtPA) is recommended for eligible patients, but data from Indonesian referral hospitals remain limited. Objective: This study aimed to describe the demographic characteristics, treatment times, and in-hospital clinical measures of patients with acute ischemic stroke receiving intravenous rtPA at Soeradji Tirtonegoro Hospital. Method: A descriptive study analyzed medical records of patients treated with intravenous rtPA between April 2022 and August 2024. Collected variables included age, sex, stroke onset, onset-to-needle time (OTN), vital parameters, comorbidities, door-to-imaging (DTI),  door-to-needle (DTN) times, early ischemic change (EIC), National Institutes of Health Stroke Scale (NIHSS) scores at admission, at 24 hours, and at discharge, Barthel Index at admission and discharge, early neurological improvement (ENI), early neurological deterioration (END), symptomatic intracerebral hemorrhage (sICH), in-hospital mortality, and length of stay (LOS). Result: Most patients were older males (62.2%; median age 62 years). Hypertension was the most common comorbidity, followed by diabetes mellitus and dyslipidemia. The median onset-to-needle time (OTN) was 240 minutes, and 80% achieved a DTI time within 25 minutes. The median DTN time was 80 minutes. Median NIHSS scores improved from 11 on admission to 6 at 24 hours and four at discharge, with ENI in 64.44% and early END in 15.56% of patients. The Barthel Index increased from 3 to 20 during hospitalization. Symptomatic intracerebral hemorrhage occurred in 6,.67%, and in-hospital mortality was 17.78 %. Conclusion: Intravenous rtPA thrombolysis improved neurological and functional measures among acute ischemic stroke patients. However, the prolonged door-to-needle time indicates the need for enhanced in-hospital workflows to accelerate treatment delivery.
Enhancing Stroke Risk Prediction with Explainable AI: Leveraging Resampling and Machine Learning for Improved Accuracy Minhazul Alam Mahin; Md. Mominul Islam; Md. Zulfikar Alam; Arnob Dutta Pollob; Oxita Zaman
Journal of Neurointervention and Stroke Vol. 1 No. 2: NOVEMBER 2025
Publisher : Neurointervention Working Group of Indonesian Neurological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63937/jnevis-2025.12.16

Abstract

Highlight: Advanced resampling techniques improved class balance in stroke datasets Gradient Boosting with SMOTE reached 92% accuracy with SHAP interpretability ABSTRACT Introduction: Stroke represents a significant global health concern, impacting millions worldwide and contributing substantially to morbidity and mortality. Early detection and accurate risk prediction remain critical for effective prevention strategies. Objective: This study aimed to improve stroke risk prediction by employing machine learning algorithms on health survey data to identify key predictors and enhance predictive performance. Method: A dataset derived from the National Health and Nutrition Examination Survey, comprising 4,603 participants, was utilized. The dataset exhibited class imbalance, with only 7.86% of individuals diagnosed with stroke. To address this imbalance, advanced resampling techniques, including SMOTE, SMOTETomek, and ADASYN, were applied. A range of tree-based algorithms was implemented, including Gradient Boosting, AdaBoost, XGBoost, and a Voting Classifier integrating Decision Tree, AdaBoost, and Gradient Boosting classifiers. Model evaluation included accuracy and AUC scores. Explainable Artificial Intelligence (XAI) analyses were conducted using SHAP (SHapley Additive exPlanations) to interpret feature importance. Result: The Gradient Boosting classifier, in conjunction with SMOTE, achieved the highest performance with an accuracy of 92% and an AUC score of 0.70. SHAP analysis identified age, general health condition, marital status, and BMI as the most influential predictors of stroke risk. Conclusion: This study underscores the essential need for ongoing advancements in early stroke detection methodologies. The findings highlight the transformative potential of machine learning and XAI in predictive healthcare, offering valuable insights for stroke prevention strategies.
Profile of Non-Hemorrhagic Stroke Patients Who Received Endovascular Stenting Services at Dr. Kariadi General Hospital Semarang Freddy Hasudungan Aritonang; Aditya Kurnianto; Yovita Andhitara
Journal of Neurointervention and Stroke Vol. 1 No. 2: NOVEMBER 2025
Publisher : Neurointervention Working Group of Indonesian Neurological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63937/jnevis-2025.12.17

Abstract

Highlight: This study describes profiles of patients who received endovascular stenting services A descriptive method study was selected to offer a thorough overview ABSTRACT Introduction: Endovascular stenting (ES) is an alternative therapy to carotid endarterectomy (CEA) and best management therapy (BMT) for intracranial and extracranial arterial stenosis with or without symptoms. Atherosclerosis can cause non-hemorrhagic stroke, and the risk factors include diabetes mellitus, dyslipidemia, smoking, hypertension, and advanced age. Objective: This study aimed to determine the profile of non-hemorrhagic stroke patients who received ES services at Dr. Kariadi General Hospital, Semarang. Method: This research used a descriptive method with sampling carried out sequentially using electronic patient medical record data from January 2023 to November 2024. Result: ES services were obtained for 67 patients, of whom 39 were men (58.2%). The largest age groups were between > 50-60 years and > 60-70 years, accounting for 37.3%. The stenosis in the proximal vertebral artery was performed by ES in 70.1% patients. ES was performed on 62.7% patients, with an average stenosis degree of 59.8% in the 50%–69% range (moderate to severe stenosis group). Risk factors for atherosclerosis in this study included hypertension in 67.2% patients and dyslipidemia in 52.2%. There were 71.6% of patients who did not have risk factors for diabetes mellitus. In this study, only 2 patients’ data from medical records were examined for smoking risk factors. Conclusion: Non-hemorrhagic stroke patients who received endovascular stenting services at Dr. Kariadi General Hospital, Semarang, were men in their 50s and 60s, with lesions in the proximal vertebral artery with an average stenosis degree of 59.8%. Risk factors included hypertension, age, and dyslipidemia.
Endovascular Stenting for Chronic Headache Secondary to Cerebral Venous Sinus Stenosis: A Case Report Izza Ayudia Hakim; Bagus Dermawan; Yingying Zhang; Guangzheng Zhang
Journal of Neurointervention and Stroke Vol. 1 No. 2: NOVEMBER 2025
Publisher : Neurointervention Working Group of Indonesian Neurological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63937/jnevis-2025.12.20

Abstract

Highlight: CVSS is an underdiagnosed but reversible cause of chronic headache Venous stenting effectively restores venous outflow and reduces ICP Early recognition and intervention lead to rapid and sustained symptoms resolution ABSTRACT Introduction: Chronic headache poses a significant diagnostic and therapeutic challenge. Cerebral venous sinus stenosis (CVSS) is an underrecognized yet important etiology in which stenosis impairs venous outflow and elevates intracranial pressure, leading to headache. Endovascular stenting offers a therapeutic approach by mechanically restoring venous flow. Case: A 43-year-old female presented with a chronic headache for 3 months, refractory to multimodal medical therapy. Digital subtraction angiography (DSA) confirmed stenosis in the bilateral transverse sinuses. The patient subsequently underwent successful endovascular venous stenting. Conclusion: This case underscores that CVSS is a potentially treatable cause of chronic headache. Endovascular intervention can provide rapid symptomatic relief for patients with medically refractory headache secondary to venous sinus stenosis. Long-term follow-up remains essential to confirm sustained benefit.

Page 2 of 2 | Total Record : 15

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