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Folia Medica Indonesiana The Unit of Journal Consortium and Folia Medica Indonesiana Faculty of Medicine, Universitas Airlangga Jl. Prof. Dr. Moestopo No.47, Pacar Kembang, Kec. Tambaksari, Surabaya, Jawa Timur 60132, Indonesia
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Jawa timur
INDONESIA
Folia Medica Indonesiana
Published by Universitas Airlangga
ISSN : 23558398     EISSN : 2599056X     DOI : https://doi.org/10.65346/2958-4515.2401
Core Subject : Health, Science,
Folia Medica Indonesiana, as indicated by its name, focuses on publishing good quality articles about research and education on health science and medicine in Indonesia. However, due to the fast growth of science and knowledge in these fields, we also welcome submitted articles from around the world, especially the ones that contain related matters from lower-middle income countries. Folia Medica Indonesiana is an open-access, peer-reviewed journal that is published online at least four times a year. The scope covers various aspects of basic medical sciences includes anatomy, physiology, pathology, microbiology, pharmacology, and molecular medicine) and clinical medicine (covers specialties like internal medicine, surgery, pediatrics, oncology, psychiatry, etc). We highlight the pathology and potential treatment of metabolic syndromes and infectious diseases. Folia Medica Indonesiana also encourages the publication of articles about health education. The scope includes, but is not limited to, articles that emphasize on preventive education on certain diseases in a community, also research report of various materials and/or methods to develop medical education. We recognize the importance of this type of articles to be published alongside the assigned topic in each of our yearly issues, to provide our readers with updated information in medical sciences’ research and education simultaneously.
Articles 15 Documents
Search results for , issue "Vol. 56, No. 2" : 15 Documents clear
Effect of Glucose Induction on Biofilm Density in Clinical Isolate Acinetobacter baumannii Patients in Intensive Care Unit of Dr. Soetomo Hospital, Surabaya Lindarto, Wira W; Wasito, Eddy Bagus; Debora, Kartuti
Folia Medica Indonesiana Vol. 56, No. 2
Publisher : Folia Medica Indonesiana

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Abstract

This study aimed to analyze the effect of glucose induction on the clinical isolate biofilm density of Acinetobacter baumannii. Thirteen clinical isolates of A. baumannii non biofilm forming were collected from non-DM patients who were treated at the ICU of Dr. Soetomo Hospital, Surabaya, was treated with the addition of 0.08% glucose, 0.15% glucose, 0.2% glucose, and 0.4% glucose in TSB growth media, followed by biofilm density examination with Tissue Culture Plate Method (TCPM) using 96 wells flatbottomed polyesterene tissue culture plate and read by autoreader ELISA with a wavelength of 630 nm (OD630). Biofilm density obtained was analyzed using ANOVA statistical analysis. The results of OD630 showed that the biofilm density increased significantly at the addition of 0.2% and 0.4% glucose. There was a significant increase in biofilm density at the addition of 0.2% and 0.4% glucose so that the management of blood sugar levels in ICU patients was needed before and when medical devices were installed.
Effect of Ethanol Extract of Date Palm Fruit (Phoenix dactylifera. L) on Spermatozoa Concentration of BALB/c Mice (Mus Musculus) Exposed to 2-Methoxyethanol Yassin, Tita Rudini; Yaudiwati, Rina; I'tishom, Reny
Folia Medica Indonesiana Vol. 56, No. 2
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Abstract

Antioxidants are important compounds for the human body because they function to capture free radicals causing degenerative diseases. Flavonoid and phenolic compounds in dates have antioxidant activity that can inhibit the increase in lipid peroxide and protein oxide. This study aims to prove the increase in the concentration of mice (Mus musculus) spermatozoa given ethanol extract dates and exposed to 2-methoxyethanol. Experimental animals used 35 mice (Mus musculus), divided into 5 groups (7 mice per group). The negative control group (K-) was the control group without administration of 2-methoxyethanol and date ethanol extract, the positive control group (K+) was given 200 mg/kg 2-methoxyethanol + CMC 0.5%, the treatment group 1 (P1) was given 200 mg/kg BW 2-methoxyethanol + 3.5 mg/gBW of ethanol extract dates, treatment group 2 (P2) were given 200 mg/kg BW 2-methoxyethanol + 7 mg/gBW of date palm ethanol extract, and treatment group 3 (P3) were given 200 mg/kg 2-methoxyethanol + 10.5 mg/gBW of ethanol extract dates. The results showed there were significant differences in spermatozoa concentrations between the positive control group (K+) and the negative control group (K-), treatment group 1 (P1) and treatment groups 2 and 3. mice (Mus musculus) exposed to 2-methoxyethanol.
Comparison between Exposure of Ciprofloxacin and Cefotaxime on Developing of Escherichia coli ESBL Amin, Muhammad; Wasito, Eddy Bagus; Triyono, Erwin Astha
Folia Medica Indonesiana Vol. 56, No. 2
Publisher : Folia Medica Indonesiana

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This study aimed to compare ciprofloxacin and cefotaxime exposure to develop ESBL producing Escherichia coli (E. coli). A total of 16 isolates of cefotaxime sensitive E. coli and ciprofloxacin were exposed to ciprofloxacin and cefotaxime for 14 days using the Kirby-Bauer antibiotic disc diffusion method. Colonies that grew on the edge of the inhibiting zone were exposed each day by the same method. Furthermore, we observed the occurrence of resistance to cefotaxime as ESBL screening test. Isolates were resistant, the following day the ESBL was confirmed by the Modified Double Disk Sinergy Test (MDDST) method using Cefotaxime (CTX), Ceftazidime (CAZ), Aztreonam (ATM), and Amoxilin Clavulanate (AMC) antibiotic discs. From 16 isolates of ESBL producing E. coli exposed to ciprofloxacin, it was obtained 4 (25%) to ESBL E. coli. ESBL production occurred after E. coli was exposed to ciprofloxacin on days 5, 6, 7, and 12. While those exposed to cefotaxime none becomes ESBL E. coli. There was no difference between ciprofloxacin and cefotaxime exposure to develop ESBL producing E. coli (p=0.101; Chi-square).
Therapy Effect of Red Dragon Fruit (Hylocereus polyrhizus) Peel Extract to Increase the Number of Sertoli Cells On BALB/c Mice (Mus musculus) Exposed to Lead Acetate Wulandari, Evy; I'tishom, Reny; Sudjarwo, Sri Agus
Folia Medica Indonesiana Vol. 56, No. 2
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Abstract

Lead is the free radicals and heavy metals of major pollutants in the environment. Lead is toxic and cumulative. Red dragon fruit (Hylocereus polyrhizus) peel extract is a natural antioxidant. Red dragon fruit peel extract can be used to stabilize free radicals by supplementing electron deficiencies and inhibiting chain reactions. This study aimed to analyze therapy effect of red dragon fruit peel extract to increase the number of Sertoli cells on BALB/c mice (Mus musculus) exposed to lead acetate. Fourty mice were divided into 5 groups (each group consisted of 8 mice). K- group was the control group without lead acetate and dragon fruit peel extract administration, K + group was given 100 mg/KgBW lead acetate orally on the 1st day until day 14th.. P1, P2, and P3 group were continued with red dragon extract orally on the 15th day until 39th day. P1 with dose 250 mg/KgBW, P2 with dose 500 mg/KgBW, and P3 with dose 1000 mg/KgBW. The result showed significant difference (P<0.05) in the number of Sertoli cells between K+ and P1, P2, P3 group. In conclusion, dose 500 mg/kgBW of red dragon fruit peel extract can be used as the most effective therapy to increase the number of Sertoli cells on mice exposed to acetate lead.
Effect of Adaptive Exercise on Body Temperature in Children with Motoric Disorder Mulyadi, Soffil Yudha; Rejeki, Purwo Sri; Tinduh, Darmayanti; Sari, Gadis Meinar; Prasetya, Rizka Eka
Folia Medica Indonesiana Vol. 56, No. 2
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Abstract

Motoric disorder in child increased every year, especially cerebral palsy. Children with motoric disorder which is majority experiencing long immobilization results in their general condition declining. One of this declining appears on body temperature in child, even lead to hypothermia. A simple exercise which applicatively performed at home can be a simple solution to maintain general condition, especially body temperature. The purpose of this study was to determine effect of adaptive exercise on body temperature change in children with motoric disorder. This study was an experimental study of one group pre and posttest. A total of 31 children (11 girls and 20 boys) aged 2-10 years old performed adaptive exercise consist of warming up 5 minutes, core movement 25 minutes, cooling down 5 minutes. Data were analyzed by paired T test. Body temperature in pretest was 36.12 ± 0.53oC, and body temperature in posttest was 36.63 ± 0.6oC, with p = 0.00. Adaptive exercise can increase body temperature but still in normal range.

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