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All Journal Folia Medica Indonesiana Jurnal NERS Majalah Kedokteran Gigi Indonesia JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya The Southeast Asian Journal of Midwifery Care : Jurnal Ilmiah Ilmu Kesehatan Jurnal Respirasi (JR) Biomolecular and Health Science Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Pediomaternal Nursing Journal JURNAL PENELITIAN KEBIDANAN & KESPRO Indian Journal of Forensic Medicine & Toxicology INDONESIAN MIDWIFERY HEALTH AND SCIENCES JOURNAL Indonesian Community Journal Indonesian Andrology and Biomedical Journal AKSONA Strada Jurnal Ilmiah Kesehatan (SJIK)

Gadis Meinar Sari

Departemen Ilmu Faal, Fakultas Kedokteran, Universitas Airlangga

Author-ID : 2650022

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

Published : 32 Documents Claim Missing Document

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Calorie Restriction and Moderate-Intensity Continuous Exercise Decrease Free Fatty Acid Levels and Visceral Fat Weight on High Calorie Diet Female Mice Ahmad Rukhani Lutfi; Lilik Herawati; Widjiati; Gadis Meinar Sari
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14944

Objective: This study aimed to analyze the effect of a combination of calorie restriction and moderateintensity continuous exercise on FFA levels and visceral fat weight in female mice exposed to a high-caloriediet.Material and Method: This research was randomized posttest used only control group design with femalemice as the sampl Balb/c mice (Mus musculus), 8 weeks old, 20-30 grams. It was randomly divided into fourgroups, namely C (control group), G1 (moderate-intensity continuous exercise group), G2 (calorie restrictiongroup), and G3 (combination group calorie restriction and moderate-intensity continuous exercise) wherein every group consisted six female mice. Providing a high-calorie diet using ad libitum plus D40 as muchas 3-5% of calories (0.0325 mL/gBB) for 4 weeks. The provision of a high-calorie diet was done usingthe sonde technique. Calorie restriction was done 3x/week in 4 weeks by limiting calorie intake to 50% ofstandard foods. The moderate-intensity continuous exercise was carried out by swimming for 15 minutesplus 6% gBB loading, it was done 3 times/week for 4 weeks. The measurement of cholesterol, visceral fatweight, and FFA level was done at the end of treatments.Results: The results found that the mean of cholesterol of C C (171.00±47.74 mg/dL), G1 (126.00±15.92 mg/dL), G2 (131.50±22.37 mg/dL), G3 (121.17±21.23 mg/dL) dan (p=0.032). The mean weight of visceral fatat C (0.68±0.23 grams), G1 (0.25±0.08 grams), G2 (0.28±0.06 grams), G3 (0.20±0.03 grams) and (p=0.000).The mean FFA levels were at C (1511.34±6.19 µmol/L), G1 (1419.31±53.61 µmol/L), G2 (1458.20±28.89µmol/L), G3 (1451.55±43.77 µmol/L) and (p=0.004).Conclusion: Based on the results of the study, it could be concluded that the provision of calorie restrictionand moderate-intensity continuous exercise significantly reduced cholesterol levels, visceral fat weight, FFAlevels and in female mice exposed to a high-calorie diet

Effect of Moderate-Intensity Acute Physical Activity on Decreasing Cortisol Levels in Obese Female Cornelius Coli; RizkaEka Prasetya; GadisMeinar Sari; Purwo Sri Rejeki
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15719

Correlation between obesity and successful ovulation induction with Clomiphene citrate Rida Eka Setiani; Sri Ratna Dwiningsih; Gadis Meinar Sari
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 6, No 1 (2022): Journal Qanun Medika Vol 6 No 01
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v6i1.8309

ABSTRACTOvulation induction with clomiphene citrate is a hormonal therapy for infertile women with impaired ovarian function caused by dysregulation of the hypothalamus and pituitary, affecting egg development and ovulation. Several factors, such as obesity, influence the success rate of treatment with clomiphene citrate. According to the Asia-Pacific classification, obesity was classified into two categories, obesity type I (25-29,9 kg/m2) and obesity type II (≥30 kg/m2). The success rate of ovulation induction with clomiphene citrate in obese infertile women at Graha Amerta Fertility Clinic in Dr. Soetomo General Hospital on July 2019 – July 2020 was about 22.8%. The research aimed to analyze the correlation between obesity with successful ovulation induction with clomiphene citrate. This research method was observational analytic research with a cross-sectional approach. The data were collected from medical records of infertile obese women who undergo ovulation induction with clomiphene citrate. According to inclusion criteria, the number of samples is 79 cycles of infertile obese women who undergo ovulation induction with clomiphene citrate. Data analysis using Chi-square test. The result showed that successful ovulation induction in obese type I was 17.7% and in obese type II was 5.1%. There was a correlation between obesity with successful ovulation induction with clomiphene citrate (p=0.009). In conclusion, there was a correlation between obesity with successful ovulation induction.Keyword : ovulation induction, clomiphene citrate, obeseCorrespondence : sri-r-d@fk.unair.ac.idation induction.

Physical Exercise and Bone Health Gadis Meinar Sari
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 3, No 1 (2019)
Publisher : Universitas Muhammadiyah Surabaya

ABSTRACTExercise was a planned and structured physical activity in which there was a movement repetition to maintain or enhance one or more components of physical fitness. The physical exercise on biological functions gave positive effects such as improving, but in certain circumstances, it could also give a negative effect such as inhibiting or disturbing the level of individual, system, cell, and molecular. Likewise the effect of physical exercise on bones, many factors affected bone both positively and negatively, among others; the dose of physical exercise which included frequency, intensity, type and time. The dosage of physical exercise was individual on each person. Some studies found that moderate intensity physical exercise provided positive benefits on bones. One of them was affecting the process of proliferation and differentiation of osteoblast, which was one of bone cells that had a function to form bone matrix. Moderate intensity physical exercise combined with salmon calcitonin would increase mouse bone density. Moderate-speed walking exercise would cause changes in IL-6 serum levels which had a role in the process of stem cell differentiation into osteoprogenitor and directly affected adult osteoblasts, whereas changes in PTH serum levels in the sub-acute phase of exercise played a role in the positive uncoupling process of bone remodeling directly.Keywords : moderate intensity physical exercise, bone healthCorrespondence to : gadis-m-s@fk.unair.ac.id ABSTRAKOlahraga adalah latihan fisik yang merupakan bagian dari aktivitas fisik yang terencana, terstruktur, terdapat repetisi gerakan, dan mempunyai tujuan mempertahankan atau meningkatkan salah satu atau lebih komponen kebugaran fisik. Pengaruh latihan fisik terhadap fungsi biologis dapat memberi pengaruh positif yaitu bersifat memperbaiki, akan tetapi pada keadaan tertentu dapat pula memberikan pengaruh negatif yaitu menghambat atau mengganggu baik pada tingkat individu, sistem, sel maupun molekul. Demikian juga pengaruh latihan fisik terhadap tulang, banyak faktor yang mempengaruhi tulang secara positif maupun negatif, antara lain adalah dosis latihan fisik yang meliputi frekuensi, intensitas, jenis dan waktu melakukan latihan fisik. Dosis latihan fisik bersifat individual pada setiap orang. Beberapa penelitian menunjukkan bahwa latihan fisik intensitas sedang memberikan manfaat positif pada tulang. Antara lain mempengaruhi proses proliferasi dan diferensiasi sel osteoblas yaitu salah satu sel tulang yang berfungsi membentuk matriks tulang. Latihan fisik intensitas sedang dikombinasikan dengan salmon kalsitonin akan meningkatkan kepadatan tulang tikus. Latihan jalan dengan kecepatan sedang akan menyebabkan perubahan kadar IL-6 serum yang berperan pada proses diferensiasi stem cell menjadi osteoprogenitor dan secara langsung berpengaruh pada osteoblas dewasa, sedangkan perubahan kadar PTH serum pada fase subakut latihan berperan pada proses positive uncoupling remodeling tulang secara langsung.Kata kunci : latihan fisik intensitas sedang, kesehatan tulangKorespondensi : gadis-m-s@fk.unair.ac.id

Effects of nano-hydroxyapatite paste on enamel microporosity after bleaching treatment Nikmatus Sa'adah; Gadis Meinar Sari; Elyana Asnar
Majalah Kedokteran Gigi Indonesia Vol 4, No 1 (2018): April
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Bleaching or teeth whitening is a popular dental conservative treatment to enhance aesthetics. Bleaching treatment in many cases has successfully improved aesthetics but still remains the side effects. It can cause some changes in enamel structure leading to demineralization characterized by the emergence of microporosity on the enamel surface. Nano-hydroxyapatite is potential to re-mineralize earlyenamel lesions. This study aims to identify the effect of nano-hydroxyapatite on enamel microporosity after bleaching treatment. Twelve rabbits were randomly divided into two groups. The control and treatment group administered a placebo and nano-hydroxyapatite paste respectively, for 7 days after bleaching treatment. Once the treatment was completed, the rabbit was sacrificed, the jaw was decapitated, upper and lower incisors of the rabbit were separated from the jaw. Subsequently, the sample preparation wasconducted for examination of enamel microporosity depth by using scanning electron microscope. The results showed the control group had more microporositycompared to the treatment group. The independent t-test result showed that enamel microporosityhad a significant value of 0.003 (p <0.05) meaning that enamel microporosity between both groups had a significant difference. The conclusion of this study was administration of nan-hydroxyapatite paste reduced enamel microporosityin the administration of nano-hydroxyapatite pastes compared to the placebo pastes after bleaching treatment.

Pengaruh Pemberian Kafein Per Oral terhadap Kadar Gula Darah pada Tikus Wistar (Rattus norvegicus) Hiperglikemia Ana Silvi Ni'ma; Gadis Meinar Sari; Lucky Prasetyowati
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 4 No. 1 (2017): Jurnal Farmasi dan Ilmu Kefarmasian Indonesia
Publisher : Universitas Airlangga

Pendahuluan: Kafein adalah zat utama yang terkandung dalam kopi yang merupakan minuman yang digemari oleh masyarakat di seluruh dunia. Pengaruh kafein terhadap kadar gula dalam darah masih belum jelas apakah dapat menaikkan atau menurunkan kadar gula darah. Beberapa penelitian membuktikan bahwa kafein dapat meningkatkan kadar gula darah melalui efeknya terhadap penurunan sensitivitas insulin. Sebaliknya, penelitian lain membuktikan bahwa kafein dapat memberikan efek perlindungan tubuh terhadap diabetes mellitus melalui pengaruhnya dalam meningkatkan sensitivitas insulin. Tujuan: Untuk mengetahui efek pemberian kafein per oral terhadap kadar gula darah pada tikus normal maupun tikus hiperglikemia. Metode: Penelitian ini menggunakan 36 tikus (Rattus norvegicus) yang dibagi menjadi 4 kelompok, yaitu kelompok tikus hiperglikemia yang diberi perlakuan (K1), kelompok tikus hiperglikemia kontrol (K2), kelompok tikus normal yang diberi perlakuan (K3) dan kelompok tikus normal kontrol (K4). Kelompok perlakuan (K1 dan K3) diberi kafein dengan dosis 3,22 mg/200 gram BB per oral setiap hari selama 3 hari. Kadar gula darah diukur sebelum dan setelah perlakuan. Analisis data menggunakan paired t-test dan effect size yang memberikan hasil signifikan apabila p < 0,05. Hasil: Hasil menunjukkan bahwa pemberian kafein secara oral memberikan efek yang signifikan terhadap kadar gula darah tikus normal dan hiperglikemia. Kesimpulan: Efek pemberian kafein terhadap kadar gula darah pada tikus normal dan hiperglikemia sebesar 81,1% dan 97,7%. Sehingga dapat disimpulkan bahwa pemberian kafein per oral terhadap kadar gula darah tikus normal dan hiperglikemia dapat meningkatkan kadar gula darah pada tikus normal dan hiperglikemia.

Early Stunting Detection Education as an Effort to Increase Mother's Knowledge about Stunting Prevention Gadis Meinar Sari
Folia Medica Indonesiana Vol. 57 No. 1 (2021): March
Publisher : Universitas Airlangga

Stunting is one of the main nutritional problems that is still common in children under five and has serious health impacts. The results of National Health Research (Riskesdas) in 2018 showed the prevalence of stunting at 30.8%, indicating that 1 out of 3 Indonesian children are still stunted. Probolinggo Regency is a priority area for stunting handling in 2019 with a prevalence of 50.2% according to a report from the National Team for the Acceleration of Poverty Reduction (TNP2K). One of the factors that directly affect the incidence of stunting is low birth weight (LBW), while the mothers' knowledge level of health is an indirect factor that affects the growth conditions of children under five. The purpose of this study was to analyze the effect of providing stunting early detection education on maternal knowledge regarding stunting prevention. This is a pre experimental research study with one group pre-post test design, children aged 0-24 months as the research subjects. The case group consisted of stunted children (BL/A <-2 SD Z-score), while the control group consisted of normal children according to the BL/U indicator. The number of research subjects for the case and control groups was 40 with mothers of the toddlers as research respondents. The samples were selected using total sampling technique. Data were analyzed using dependent T test and linear regression. The results suggested that at the beginning of the session before provided education about early detection of stunting, mothers with stunting toddlers had lower level of knowledge (73.3%) than those with normal toddlers (77%). After provided with education, the knowledge level of mothers with stunted toddlers appreared to be higher (89%) than those with normal children (87.6%), with significant increase in each group (P <0.05). It can be concluded that education on stunting detection can significantly improve mothers' knowledge regarding the prevention of stunting in children aged 0-24 months. Providing regular education, both by nutrition workers at the health center and integrated service post (posyandu) cadres, is necessary as an effort to prevent stunting to the maximum.

Factors Correlated with the Intention of Iron Tablet Consumption among Female Adolescents Riri Aprianti; Gadis Meinar Sari; Tiyas Kusumaningrum
Jurnal Ners Vol. 13 No. 1 (2018): April 2018
Publisher : Universitas Airlangga

Introduction: Anaemia in female adolescents tends to have a negative impact that is likely to later arise in pregnancy, labour and childbirth. The prevalence of iron deficiency anaemia in female adolescents in Indonesia is thirty percent. Indonesia runs an iron tablet program for female adolescents. However, with the running of the program, it is not clear what factors are correlated with the intention of iron tablet consumption among female adolescents. The purpose of this study was to analyse the factors correlated with the intention of iron tablet consumption among female adolescents.Methods: This research used a cross-sectional design. The sample consisted of 100 students in senior high school in Surabaya, chosen by proportional random sampling. The independent variables were parent income, knowledge, perceived susceptibility, perceived seriousness, perceived threats, perceived benefits, perceived barriers, and perceived self-efficacy. The dependent variable was female adolescent intention related to consuming iron tablets. The data was collected using a questionnaire and analysed by a chi square test with a level of significance α<0.05.Results: There was a significant correlation between perceived threat (p=0.02), perceived benefit (p=0.01), perceived barrier (p=0.02) and perceived self-efficacy (p=0.00) and female adolescent intention related to consuming iron tablets. There was no correlation between parental income, adolescent knowledge, perceived susceptibility, and perceived seriousness with the intention to consume iron tablets.Conclusion: From this research, it has been concluded that the factors related to the intention to consume iron tablets in female adolescents were perceived threat, perceived benefit, perceived barrier and perceived self-efficacy. Increasing the confidence of female adolescents in association with the importance of avoiding anaemia by consuming iron tablets is crucial so then they can maintain their health and prevent diseases due to anaemia later on.

The Comparison of Total Cholesterol Level in DMPA and Combination Injection Contraception Users Rara Yumna Elfrida; Gadis Meinar Sari; Sri Ratna Dwiningsih; Pudji Lestari
Pediomaternal Nursing Journal Vol. 6 No. 2 (2020): VOLUME 6 NO 2 SEPTEMBER 2020
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/pmnj.v6i2.20352

Introduction: Hormonal injection contraception is the most widely used method of contraception in Indonesia. In long-term use, one of the side effects of injection contraception is changes in lipid metabolism in the body caused by the accumulation of hormones in the body. Two types of injectional contraception are widely used in Indonesia, namely combined injection and DMPA injection; different hormonal content has various side effects on the lipid profile. This study aimed to compare the total cholesterol level between acceptors of DMPA injection and combined injection.Methods: This study used an observational analytic method with a cross-sectional approach. The sample size is 60 respondents, including 30 DMPA injection acceptors and 30 combination injection acceptors. The sampling method uses a purposive sampling technique The independent variable in this study was the total cholesterol level of the acceptor, and the dependent variable was the acceptor of DMPA injection and the combination injection acceptor. Analysis of research data used the Independent T-test with α=0.05.Results: The results of the bivariate analysis found significant differences in total cholesterol levels in the DMPA injection contraception acceptor and combination injection with p= 0.037. It was found that overall cholesterol levels of DMPA injection acceptors were higher.Conclusion: There is a difference in total cholesterol levels in the DMPA injection contraception acceptor with a combination injection contraception acceptor.

Pre-Operative Enhanced Recovery After Surgery (ERAS) Protocol Compliance Towards Major Surgery Patients at Dr. Soetomo General Hospital, Surabaya Ahmad Sabili Rifa'i; Vicky Sumarki Budipramana; Gadis Meinar Sari
Biomolecular and Health Science Journal Vol. 3 No. 1 (2020): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bhsj.v3i1.19064

Introduction: The implementation of ERAS protocol can optimize patients after surgery, which in turn can reduce burdens both for patient and hospital. The purpose of this study is to describe the compliance and consistency of ERAS in the pre-operative period of surgery patients in Dr. Soetomo General Hospital Surabaya. Methods: We conducted consecutive observation of major surgical patients for 4 weeks. The type of surgery observed was digestive, thoracic and cardiovascular, and gynecological surgery. The pre-operative period will be calculated for compliance based on the ERAS international protocol. All data of compliance presented descriptively.s.Results: A total of 36 major surgery patients of which 7 (19,4%) were digestive surgeries, 14 (38,9%) were thoracic and cardiovascular surgeries, and 15 (41,7%) were gynecological surgeries. Overall compliance of the ERAS protocol in the pre-operative period of major surgery patients was 91%. The compliance of ERAS protocol in the pre-operative period of digestive surgery patients was 80%, in thoracic and cardiovascular surgery patients was 93,4% and gynecologic surgery patients was 84.3%. Major surgery patients with ≥90% compliance was 25%. Digestive surgery patients with ≥90% compliance was 0%. Thoracic and cardiovascular surgery patients with ≥90% compliance was 64,3%. Gynecologic surgery patients with ≥90% compliance was 0%.Conclusion: : Pre-operative elements of ERAS protocol in major surgery including digestive, thoracic and cardiovascular, and gynecologic surgery in Dr. Soetomo General Hospital, Surabaya needs to be improved.

Co-Authors adella wahyuningsih Agustina Yasinta Yami Ahmad Rukhani Lutfi Ahmad Sabili Rifa'i Aizah Ari Setyana Yuli Akhmad Jayadi Akmal Zidan Alaudin Alfian Nurfaizi Alfiyah Zahra Ulya Ana Silvi Ni'ma Anggreini Wahyu Prastika Annas, Jimmy Yanuar Ashon Sa'adi Ashon Sa’adi Atika Atika Bakhtiar, Arief Budipramana, Vicky Sumarki Cakra Waritsu Choesnan Effendi Cornelius Coli Cornelius Coli Damayanti Tinduh Dian Lestari Dwikora Novembri Utomo Dyah Ayu Pradnyaparamitha Eighty Mardiyan K, Eighty Elyana Asnar Fadhilah Rahmaputri Fauziah Ariviani Felisita Maritza Abidanovanty Fitriyatul Qulub Gatut Hardianto, Gatut HERAWATI, LILIK Heri Suroto Hermina Novida, Hermina I Gusti Made Reza Gunadi Ranuh I'tishom, Reny Irdayanti Irdayanti Isnin Anang Marhana Ivon Diah Wittiarika Izzati, Dwi Jihadna Prima Santika Ruslan Musanip Kintan Adelia Farahannisa Kurniani Fatma Hardini Lucky Prasetyowati Mei Indarti Melynda Trilamsari Putri Nabila Sayyidah Fairuz Zen Nathanael Jordan Nikmatus Sa’adah Paulus Liben Prihartini Widiyanti Pudji Lestari Rara Yumna Elfrida Rejeki, Purwo Sri Rida Eka Setiani Riri Aprianti RizkaEka Prasetya Soebagjo, Hendrian Dwikoloso Sri Ratna Dwiningsih Tiyas Kusumaningrum Wahyul Anis Widjiati Yanuar Alfan Triardhana Yudi Her Octaviono Zakaria Sendy Wardana

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