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JURNAL SAINS DAN TEKNOLOGI INDONESIA

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Articles 7 Documents

Search results for , issue "Vol. 9 No. 1 (2007)" : 7 Documents clear

PENGARUH SITOTOKSIK EKSTRAK BUAH MAHKOTADEWA [Phaleria macrocarpa (Scheff) Boerl.] TERHADAP SEL KANKER LESTARI HeLA Pertamawati, Pertamawati
Jurnal Sains dan Teknologi Indonesia Vol. 9 No. 1 (2007)
Publisher : Badan Pengkajian dan Penerapan Teknologi

Fruits of mahkotadewa (Phaleria macrocarpa (Scheff) Boerl). has been used to cure various health problems, including empirical treatment for cancer. The therapeutic effect of natural material is related to the chemical compounds it contain. In fruits of Phaleria macrocarpa, various chemicals are present such as flavonoid and tannin, both show anticancer activity, as well as other unknown ones presumably supportive for cancer treatment. An in vitro experiment is therefore set up with the objective of examining the effect of fruit extract on human uterine cervical carcinoma cells (HeLa cells). Various concentrations: 5, 10, 25, 50 and 100 ppm of fruit extract were evaluated. Observations were made 24, 72 and 120 hour after incubating HeLa cells in each treatments. The results showed that fruit might inhibit the growth of HeLa cells. Inhibitory concentration (IC50) of fruit extract after 24 hours of incubation is 6,21 ppm, after 72 hour of incubation is 5,09 ppm dan 5,73 ppm for 120 hour of incubation. Inhibitory potential of fruits in 72 hour of incubation is a highest ones. The effect might be associated to the active compounds contained in these material.

AKTIVITAS ANTIOKSIDAN BEBERAPA SPESIES RUMPUT LAUT DARI PULAU SUMBA supriyono, agus
Jurnal Sains dan Teknologi Indonesia Vol. 9 No. 1 (2007)
Publisher : Badan Pengkajian dan Penerapan Teknologi

The specimens of Caulerpa racemosa ,Codium edule, Halimeda tuna, Ulva reticulata, Dictyota dichotoma, Sargassum crassifolium, and Turbinaria ornata were collected from the Sumba Islands waters, Indonesia. The crude methanol extracts of those specimens, n-hexane, dichloromethane and water fraction of Sargassum crassifolium were tested for antioxidant activity using the thiocyanate method. The methanol extracts of Caulerpa racemosa, Halimeda tuna, Ulva reticulata, Dictyota dichotoma, Sargassum crassifolium, and Turbinaria ornata showed antioxidant activity, but extracts of Codium edule did not show antioxidant activity. All of the Sargassum crassifolium fractions were active, but the water fraction of this extract was more active than the other fraction.

SINTESIS DAN OPTIMALISASI GEL KITOSAN-ALGINAT Sugita, Purwantiningsih; Sjachriza, Achmad; wahyono, dwi
Jurnal Sains dan Teknologi Indonesia Vol. 9 No. 1 (2007)
Publisher : Badan Pengkajian dan Penerapan Teknologi

Shrimp shell can be used to make chitosan. The objective of this work is to sythesis and optimize chitosan-alginate gel by comparing its rheological properties. Rheological properties of chitosan were improved by gelation using glutaraldehyde as cross linker and natural hydrocolloids such as alginate. Rheological properties measured were strength, break point, rigidity, swelling and shrinking gel. The gel was made by mixing chitosan solution 2.5% (w/v), glutaraldehyde 4%, 5%, and 6% (v/v), and alginate 0%, 0.75%, and 1.0%. According Modde 5, the optimum gel happened at glutaraldehyde and alginateconcentration are 4.0% and 0.82%, respectively. This optimalization to adsorp metal ions gave gel strength, break point, pembengkakan, rigidity and shrinking properties are 881,4385 g cm-2, 1,0267 cm, 4,5313 g, 8,5179 g cm-1 and 1,6280 g, respectively.

SUATU KAJIAN INDUSTRI TEPUNG TAPIOKA RAKYAT (ITTARA) djumaali, djumaali
Jurnal Sains dan Teknologi Indonesia Vol. 9 No. 1 (2007)
Publisher : Badan Pengkajian dan Penerapan Teknologi

Industri Tepung Tapioka Rakyat (ITTARA), is one policy product of Lampung Province Goverment. This program is suitable to Lampung potency as the cassava producer the cassava producer for raw material that reach 1.6 million tons per annum (1971). Lampung is the second biggest producer after Java. ITTARA is built to empowered civil economy in villagge with capacity average of 2 and 10 topioca flour tons. This study is fucused at 2 ton capacity because for 10 ton capacity are required big capital and relative expensive for all farmer. ITTARA is expected able to assist increasing prosperity of cassava so that the farmer alwasy in a weak possition. This study will cover technology used, the settlement of disposal and by product and other aspects.

PENGARUH JENIS DAN KONSENTRASI SEMI-REFINED CARRAGEENAN (SRC) SEBAGAI STABILISATOR TERHADAP KUALITAS ES KRIM istini, sri; zatnika, achmad
Jurnal Sains dan Teknologi Indonesia Vol. 9 No. 1 (2007)
Publisher : Badan Pengkajian dan Penerapan Teknologi

Carrageenan are natural hydrocolloids which are used as gelling agent, suspending agent, emulsifier and stabilizer. Carrageenan was extracted from Eucheuma cottonii andEucheuma spinosum seaweed species. There are three types of carragenan that commonly found that are kappa, iota and lamda carrageenan. Semi-refined carrageenan (SRC) is a seaweed flour that must be extracted to recover refined carrageenan, it is expected has ability to subtitute the function of refined carrageenan so that it could economize the using of refined carrageenan. However the price of SRC is cheaper thanrefined carrageenan. Firstly this research determined the type of SRC that could be used as stabilizer in ice cream products. That compare between kappa,iota and combination of kappa-iota SRC. Ice cream is made by blend all ingredients needed with hot water (70 – 80 0C) than homogenized using mixer at high speed in 10 minutes than the formula readyto evaluate. The evaluating include pH, overrum, density, rate the sedimentation, air particle size and melting quality. The next experiment conducted to find out the better result from the selected concentration. From the experiment we conclude that kappa SRC permitted as stabilizer in ice cream at concentration 0,0168 %.

PEMANFAATAN HIDROLISAT PATI SAGU SEBAGAI SUMBER KARBON UNTUK MEMPRODUKSI BIOPLASTIK POLIHIDROKSI ALKANOAT (PHA) OLEH Ralstonia eutropha PADA SISTIM KULTIVASI FED BATCH Syamsu, K; Fauzi, A.M; hartoto, L; suryani, a; atifah, n
Jurnal Sains dan Teknologi Indonesia Vol. 9 No. 1 (2007)
Publisher : Badan Pengkajian dan Penerapan Teknologi

The objective of this resarch has been to examine the utilization of hydrolysed sago starch as main substrate to produce PHA by Ralstonia eutropha using fed batch cultivation method. The results show that the hydrolysed sago starch can be used as carbon source for the production of PHA by Ralstonia eutropha. A higherformation and accumulation of PHA can be achieved through feeding of hydrolysed sago starch in a fedbatch cultivation method. The best treatment can increase the specific product yield up to 76.54% and product concentration up to 3.72 g/L.

PENGARUH PEMBERIAN EKSTRAK BIJI KLABET (Trigonella foenum-graecum L.) TERHADAP PERKEMBANGAN UTERUS TIKUS PUTIH BETINA GALUR WISTAR PREPUBERTAL agustini, kurnia; Wiryowidagdo, Sumali; Kusmana, Dadang
Jurnal Sains dan Teknologi Indonesia Vol. 9 No. 1 (2007)
Publisher : Badan Pengkajian dan Penerapan Teknologi

Phytoestrogen is the chemical compound contains in plant which has estrogenic like effect. Estrogen has important function on woman’s sexual organ, such as proliferation of uterine and vaginal cornification. Phytoestrogen are weak agonists for estrogen and illicit statistic significantly increases in uterine wet weight, at definite dose, in uterothrophic bioassay. Biji Klabet or Fenugreek (Trigonella foenum-graecum L.) contains steroidal sapogenins such as diosgenin, tigogenin, gitogenin, yamogenin and trigoneoside, that suspected having an estrogen-likeeffect or as phytoestrogen. The aim of this research was to investigate the estrogenic effect of fenugreek’s ethanolic extract in immature rat models. These models represent the climacteric/menopause phase, where estrogen level is verylow because ovary produces no estrogen. The testing animals were divided into five groups, namely normal group, estradiol control group and three level doses of fenugreek extract (30mg/200gBW; 60mg/200gBW and 120mg/200gBW). Theresult indicated that on 120mg/200gBW, fenugreek extract significantly (=0.05) increasing wet weight uterine and proliferation of uterine, such as uterine thickness and uterine diameters. Fenugreek extract, start on 60mg/200gBW, also induces vaginal lubrication and estrus cycle.

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