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International Journal of Social and Education (INJOSEDU)
Published by CV. Adiba Aisha Amira
ISSN : -     EISSN : 30476151     DOI : Zenodo
Core Subject :
International Journal of Social and Education (INJOSEDU) is a journal that deals with social, cultural, economic, political and educational issues. Education covers all kinds of fields of education, in the sphere of family, school, and even higher education. The field of education is not confined to either general education or special education, as is the case with the social sphere.
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Articles 352 Documents
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The Impact of Agricultural Activities and Wastewater Discharge From Ogbujiriekwe Stream Nimo on Water Suitability For Domestic and Agricultural Purposes Victor Obinna Alaribe; Daniel Chinazom Anizoba; Ubah Joseph Ikenna; Louis Chukwuemeka Orakwe; John Ikedinachukwu Maduegbuna
INJOSEDU: International Journal of Social and Education Vol. 3 No. 8 (2026): International Journal of Social and Education (INJOSEDU)
Publisher : Adisam Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.23904180

Abstract

Water quality at the surface of small tropical streams is extremely vulnerable to diffuse runoff from agriculture and untreated household wastewater. Over six months, this research assessed the physico-chemical quality of Ogbujiriekwe Stream in Nimo, Anambra State, Nigeria, at four sampling stations (rainy season: June–August 2025; dry season: November 2025–January 2026). The parameters examined comprised pH, electrical conductivity (EC), total dissolved solids (TDS), nitrate-nitrogen (NO₃-N), phosphate-phosphorus (PO₄-P), sulphate, carbonate, bicarbonate, chloride, major cations (Ca²⁺, Mg²⁺, Na⁺, K⁺), boron, and ammonium-nitrogen (NH₄-N). The Weighted Arithmetic Water Quality Index (WQI) was calculated, and the findings were compared against WHO guidelines. Mean NH₄-N levels (2.6–4.6 mg L⁻¹) persistently surpassed the WHO threshold of 1.5 mg L⁻¹, and potassium was likewise elevated, pointing to inputs from agricultural fertilizers and organic waste. Every other major ion stayed within acceptable limits. WQI values spanned 132.9–159.2 (rainy season) to 173.4–244.6 (dry season), rating the water as “unsuitable for human consumption” at all stations and in both seasons.
ANTIMICROBIAL RESISTANCE AND CLINICAL SAFETY OF DOXYCYCLINE POST-EXPOSURE PROPHYLAXIS FOR BACTERIAL SEXUALLY TRANSMITTED INFECTIONS: A SYSTEMATIC REVIEW Rara Septipriskila Vira; Ketut Kwartantaya Winaya; Nyoman Yudha Santosa
INJOSEDU: International Journal of Social and Education Vol. 3 No. 8 (2026): International Journal of Social and Education (INJOSEDU)
Publisher : Adisam Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.23904237

Abstract

Objectives: To evaluate antimicrobial resistance, microbiome/resistome changes and clinical safety during event-driven doxycycline post-exposure prophylaxis (doxy-PEP), distinguishing clinical outcomes from laboratory surrogates.Methods: PubMed, Europe PMC and ClinicalTrials.gov were searched on 11 October 2026. Primary human studies were eligible; companion publications were linked to study families. Outcome-specific appraisal used RoB 2, ROBINS-I or design-appropriate JBI tools, followed by GRADE. A single review workflow was used. Synthesis followed SWiM because analysis units, phenotypes, follow-up and exposure contrasts were incompatible with pooling. Results: After deduplication, 496 database records yielded 55 retained reports; three registry results brought the evidence map to 58 reports in 37 study families. Twenty-one reports from 11 families contributed target-outcome information. High-level gonococcal tetracycline-resistance signals arose in DOXYVAC and three observational settings, with very low certainty of causal effects. These culture-conditioned results do not estimate absolute resistant-infection incidence. One selected DoxyPEP substudy showed tetracycline-resistome enrichment. In IPERGAY, gastrointestinal adverse events occurred in 62/116 versus 47/116 participants (risk ratio 1.32, 95% CI 0.999–1.74; low certainty). King County reported greater resistant S. aureus and group A streptococcal carriage in exposed screening visits, with very low certainty. DOXYVAC documented one drug-related serious fixed drug eruption. Serious-event and laboratory data did not establish comparative safety equivalence. Conclusions: Doxy-PEP has documented intolerance and organism-specific resistance signals. The magnitude of any increase in absolute resistant-infection risk remains uncertain. Clinical interpretation and surveillance should preserve distinctions between patients, sampled organisms, molecular markers and exposure periods.

Page 36 of 36 | Total Record : 352

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