MEDIXA: Journal of Modern Medical Insight & Experience
Focus MEDIXA: Journal of Modern Medical Insight & Experience is a peer-reviewed interdisciplinary journal that focuses on the development, application, and evaluation of modern medical knowledge, evidence-based healthcare practices, and innovative health technologies aimed at improving healthcare quality, patient safety, and human well-being. The journal prioritizes high-quality empirical research, systematic reviews, and practical studies that contribute to advancing clinical practice, public health outcomes, and health system innovation at local, national, and global levels. Scope The journal welcomes original research articles, review articles, and practical or applied studies in the following areas: Public Health and Community Health, Epidemiology and disease prevention, Health promotion and health education, Environmental and occupational health, Global and community health issues, Health policy and health management, Clinical and Medical Sciences, Internal medicine and clinical practice, Evidence-based clinical interventions, Patient safety and quality of care, Diagnostic and therapeutic innovations, Translational and applied medical research, Nursing and Midwifery, Nursing practice and management, Maternal and child health, Midwifery care and reproductive health, Patient-centered care and holistic nursing, Community and family nursing, Health Technology and Medical Informatics, Digital health and telemedicine, Health information systems, Artificial intelligence in healthcare, Medical devices and healthcare innovation, Data analytics and decision support systems in health, Preventive and Promotive Medicine, Preventive medicine strategies, Lifestyle medicine and wellness, Nutrition and health behavior, Non-communicable and communicable disease prevention, Screening and early detection programs, Interdisciplinary Health Studies, Health education and literacy, Psychology and behavioral health, Health economics and policy, Sociology of health and illness, Integration of technology, policy, and healthcare practice. MEDIXA encourages interdisciplinary collaboration among researchers, academics, clinicians, nurses, midwives, public health practitioners, and health technology experts to disseminate scientific findings and practical experiences that contribute to the advancement of modern healthcare and medical science.
Articles
15 Documents
<![CDATA[Gut Microbiome Dysbiosis in Type 2 Diabetes Mellitus: Mechanistic Pathways, Subtype Classification, and Therapeutic Interventions ]]>
<![CDATA[Adeel Asghar]]>
<![CDATA[ MEDIXA : Journal of Modern Medical Insight & Experience Vol. 1 No. 3 (2026): September 2026 ]]>
Publisher : <![CDATA[CV. Laskar Karya ]]>
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DOI: 10.65678/medixa.v1i3.409
<![CDATA[The global health burden of type 2 diabetes mellitus (T2DM) is growing, with over 537 million adults currently affected and a projected rise to 783 million by 2045. Despite the availability of pharmacological and lifestyle interventions, current therapies rarely reverse the underlying metabolic dysfunction, and most prior microbiome reviews have treated gut dysbiosis as a single undifferentiated phenomenon rather than distinguishing mechanistically distinct subtypes, which limits translation into targeted treatment. This review addresses that gap by synthesizing evidence from 83 original research studies sourced from PubMed, Scopus, Web of Science, and Embase (2015-2026). Gut microbiome dysbiosis is associated with insulin resistance through overlapping mechanisms, including disruption of intestinal barrier function by lipopolysaccharide (LPS)-driven endotoxemia and depletion of short-chain fatty acid (SCFA)-producing commensals such as Akkermansia muciniphila, Faecalibacterium prausnitzii, and Roseburia species. The meta-analysis reveals a substantial reduction in Akkermansia muciniphila abundance (Hedges’ g = -0.68, p = 0.002) and an overall HbA1c decrease of -0.72% (95% CI -1.12% to -0.32%) following synbiotic treatment. Building on this evidence, we propose a model that differentiates inflammatory-dominant from SCFA-depleted dysbiosis subtypes to guide targeted approaches such as probiotics, synbiotics, dietary fiber modulation, and fecal microbiota transplantation. In conclusion, the gut microbiome is a promising diagnostic biomarker and therapeutic target for T2DM, though subtype-stratified confirmatory trials are still needed.]]>
<![CDATA[Formula Milk Feeding and Diarrhea Incidence Among Infants and Toddlers in a Community Health Post, Situbondo, Indonesia ]]>
<![CDATA[Filania]]>;
<![CDATA[Iit Ermawati]]>;
<![CDATA[Bagus Supriyadi]]>
<![CDATA[ MEDIXA : Journal of Modern Medical Insight & Experience Vol. 1 No. 3 (2026): September 2026 ]]>
Publisher : <![CDATA[CV. Laskar Karya ]]>
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DOI: 10.65678/medixa.v1i3.425
<![CDATA[Diarrhea remains a significant public health problem among young children and continues to contribute to morbidity worldwide, with feeding practices being recognized as important modifiable factors associated with its occurrence. This study aimed to determine the relationship between formula milk feeding and diarrhea incidence among infants and toddlers at Tanjung Kamal Community Health Post (Pustu), Mangaran, Situbondo, Indonesia. A quantitative cross-sectional study was conducted involving 36 mother–child pairs selected using a total sampling technique from May to June 2023. Data were collected through structured questionnaires and analyzed using univariate analysis and the chi-square test for bivariate analysis. The findings showed that the majority of participants were children aged 1–3 years (61.2%) and female (66.7%). Of the total participants, 58.3% (n = 21) received formula milk, while 52.8% (n = 19) experienced diarrhea. The proportion of diarrhea cases was higher among children receiving formula milk (76.2%, n = 16/21) compared with those who did not receive formula milk (20.0%, n = 3/15). Statistical analysis revealed a significant association between formula milk feeding and diarrhea incidence (χ² = 11.09, df = 1, p < 0.001), with formula-fed children having a higher risk of experiencing diarrhea (OR = 12.8; 95% CI: 2.5–64.4). These results indicate that formula milk feeding is associated with an increased incidence of diarrhea among infants and toddlers in this community setting. Promoting exclusive breastfeeding, improving maternal knowledge regarding appropriate feeding practices, and ensuring safe formula preparation are important strategies to reduce diarrhea risk among young children.]]>
<![CDATA[Effective Cough Technique for Ineffective Airway Clearance in an Elderly Pulmonary Tuberculosis Patient: A Case Report ]]>
<![CDATA[Eko Rahman]]>;
<![CDATA[Indra Khusuma]]>
<![CDATA[ MEDIXA : Journal of Modern Medical Insight & Experience Vol. 1 No. 3 (2026): September 2026 ]]>
Publisher : <![CDATA[CV. Laskar Karya ]]>
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DOI: 10.65678/medixa.v1i3.426
<![CDATA[Ineffective airway clearance remains a leading nursing problem in patients with pulmonary tuberculosis (TB), particularly among older adults whose atypical clinical presentation often delays diagnosis and complicates respiratory management. This case is clinically noteworthy because the patient's advanced age (75 years), frail physical status, and dual burden of pulmonary TB and hypertension placed her at elevated risk of impaired secretion clearance, and her presentation illustrates how a low-cost, non-pharmacological nursing intervention can be applied safely in this vulnerable, resource-limited inpatient setting. This case report aims to describe the nursing care of an elderly patient with pulmonary TB experiencing ineffective airway clearance, managed through the application of an effective cough technique. A descriptive case study design, informed by the CARE guidelines for case reporting, was used to document the assessment, nursing diagnosis, intervention, implementation, and evaluation of care provided to a 75-year-old woman admitted with dyspnea, productive cough, and rhonchi. Data were collected through interview, physical examination, and medical record review over three consecutive days. The effective cough technique, comprising deep-breathing exercises and controlled forceful coughing, was implemented once daily across three sessions. Following the intervention, the patient's respiratory rate declined progressively from 26 breaths per minute at initial assessment to 24, 23, and 22 breaths per minute after the first, second, and third sessions respectively; sputum was expectorated more effectively, adventitious breath sounds diminished, and the patient reported reduced dyspnea and increased calmness. These outcomes are consistent with international evidence supporting breathing-cycle and coughing techniques for secretion mobilization in chronic respiratory disease. The findings reinforce the effective cough technique as an accessible, low-cost, evidence-based nursing intervention for managing ineffective airway clearance in pulmonary TB, and highlight its particular relevance for elderly patients in resource-limited settings.]]>
<![CDATA[Nursing Care for a Patient with Delusion Using Al-Qur'an Reading Therapy: A Case Report ]]>
<![CDATA[Ahmad Feri Hermawan]]>;
<![CDATA[Via Olivia Adinda]]>
<![CDATA[ MEDIXA : Journal of Modern Medical Insight & Experience Vol. 1 No. 3 (2026): September 2026 ]]>
Publisher : <![CDATA[CV. Laskar Karya ]]>
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DOI: 10.65678/medixa.v1i3.427
<![CDATA[Background: Delusion is a core positive symptom of schizophrenia, and psychoreligious interventions are widely used in Indonesian psychiatric nursing, yet their effect on delusion itself is rarely documented, especially when the result is null. Methods: A descriptive single-case study with a nursing care approach, reported with reference to the CARE guidelines, was conducted on Mr. J at Dr. Radjiman Wediodiningrat Regional Mental Hospital, Lawang, Indonesia, from 30 May to 2 June 2023. Data came from interview, observation, physical examination, and record review. Al-Qur'an reading therapy (ablution, seated recitation, about 10 minutes) was given in two sessions. Results: Mr. J reported reduced stress, unease, and anxiety and a greater sense of calm. No change in the intensity or content of his delusional beliefs was observed, and no precipitating factor was identified. No standardized symptom scale was used. Conclusion: The therapy provided short-term emotional comfort but showed no demonstrable effect on delusion after two brief sessions, consistent with evidence that psychoreligious interventions are best supported for anxiety and stress. As a single case, the findings are not generalizable; the therapy is best used as a longer-term adjunct to pharmacological and psychosocial care.]]>
<![CDATA[Behavioral Factors Influencing the Incidence of Type 2 Diabetes Mellitus: A Systematic Review ]]>
<![CDATA[Audrey Salsabila]]>;
<![CDATA[Desty Aulia Shafitri]]>
<![CDATA[ MEDIXA : Journal of Modern Medical Insight & Experience Vol. 1 No. 3 (2026): September 2026 ]]>
Publisher : <![CDATA[CV. Laskar Karya ]]>
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DOI: 10.65678/medixa.v1i3.429
<![CDATA[Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder caused by insulin resistance or insufficient insulin production, and its global prevalence continues to rise. This review aimed to identify the behavioral factors most strongly associated with T2DM incidence among the productive-age population (15-64 years), to inform targeted prevention strategies. Methods: Literature was searched on Google Scholar (the only database used) with the keywords "type 2 diabetes," "behavior," and "risk factors," restricted to case-control and cross-sectional studies published between 2019 and 2024 examining behavioral factors associated with T2DM incidence among participants aged 15-64 years. Eight studies met the inclusion criteria and were synthesized qualitatively (narrative synthesis). Findings: Two behavioral factors emerged consistently across the eight included studies: unbalanced dietary patterns, particularly excessive carbohydrate and fat consumption, and insufficient physical activity, including prolonged sedentary behavior. These findings align with the broader international evidence base on dietary and physical activity determinants of T2DM risk. Conclusion: Public health interventions combining dietary modification with structured physical activity promotion, including digital and social-media-based strategies, represent a promising avenue for T2DM prevention specifically targeted at diet and physical activity, the two most actionable behavioral factors identified. Limitations of this review, including reliance on a single search database and the absence of formal risk-of-bias assessment, are discussed alongside recommendations for future, more methodologically comprehensive reviews.]]>
