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Alchemy : Journal of Chemistry
Published by Universitas Islam Negeri Maulana Malik Ibrahim Malang
ISSN : 20861710     EISSN : 24606871     DOI : http://dx.doi.org/10.18860/al
Core Subject : Science, Engineering,
Chemical Engineering, Chemistry & Bioengineering Chemistry Energy Materials Science & Nanotechnology
ALCHEMY: Journal of Chemistry (eISSN 2460-6871) is a scientific journal that focus on chemistry. This journal publishes a scientific article that cover research and review articles. Research topics for this journal such as natural science, physical chemistry, inorganic chemistry, organic chemistry, environment, biochemistry, marine, energy and other related-sciences. ALCHEMY: Journal of Chemistry also accepts article about halal products and chemistry on Islamic perspectives.
Arjuna Subject : Kimia(semua kategori) - Kimia (Lain-Lain)
Articles 6 Documents
 1 
Search results for , issue "ALCHEMY (Vol. 4, No.2" : 6 Documents clear
Antioxidant Activity of Flavonoid from Rhizome Kaemferia galanga L. Extract Hayati, Elok Kamilah; Ningsih, Rachmawati; Latifah, Latifah
ALCHEMY ALCHEMY (Vol. 4, No.2
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (320.957 KB) | DOI: 10.18860/al.v4i2.3203

Abstract

Kaemferia galanga L. rhizome is a traditional crop which is widely used for herbal medicine.  This research is started from the extraction of maceration using ethanol 80% and partition with chloroform:water. 80 % ethanol extract and chloroform fraction tested antioxidant activity with DPPH (1,1-diphenyl-2-picrylhydrazyl), phytochemicals with reagents, separation of the active compound by TLC (thin layer chromatography) analytical and preparative TLC, the identification of compounds with sliding reagent using UV-Vis. The test results on the antioxidant activity of 80% ethanol extract of 64,93% (100 ppm) and chloroform fraction of 54,9 % (100 ppm) with indigo IC50 of 13,07 mg/mL and 81,9 mg mL. 80 % ethanol extract and chloroform fraction has potential as a source of natural antioxidants. Phytochemical test showed 80% ethanol extract contains flavonoids, alkaloids and tannins. At the chloroform fraction extract containing flavonoids. The separation of the active compounds with analytical TLC using eluent PE: ethyl acetate (5: 1) resulted in 7 stain (Rf 0,06 to 0,96) and preparative TLC produce 8 spots (Rf from 0,19 to 0,83). Results from UV-Vis spectrum can be presumed that such a class of flavonoid compounds flavanones or dihidroflavonol. It can be seen from the wavelength range 210-285 nm in the bands I and 300-550 nm in band II. The addition of the reagent slide showed the presence of hydroxyl groups in ring A, B and C and O-hydroxy on ring A. Keywords: antioxidant activity, Kaemferia galanga rizhome, sliding reagent, Thin Layer Chromatography, 1,1-diphenyl-2-picrylhydrazyl 
Antibacterial Activity of the Red Algae Eucheuma cottonii Extract from Tanjung Coast, Sumenep Madura Andriani, Zulli; Fasya, Ahmad Ghanaim; Hanapi, Ahmad
ALCHEMY ALCHEMY (Vol. 4, No.2
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (262.778 KB) | DOI: 10.18860/al.v4i2.3197

Abstract

AbstractRed alge Euchema cottonii is one of the biological source that has benefits. The aim of this study is to determine the effectiveness of antibacterial red algae Eucheuma cottonii extract. Isolation of active compounds was performed by maceration method using methanol. The methanol extract was hydrolyzed using HCl 2 N and partitioned by ethyl acetate, chloroform, petroleum ether and n-hexane solvents. The antibacterial assessment was determined using disc diffusion method againts bacteria Staphylococcus aureus and Escherichia coli. Identification of active compound was conducted by reagents test. The results showed that the best solvent to extract algae was methanol with 20.7% rendemen. The methanol extract 4% gives the highest inhibition at concentrations was 7.85 mm; followed by n-hexane and chloroform were 1.0 and 0.6 mm. However, bath ethyl acetate and petroleum ether extract depicted no inhibition zone. The identification test showed the presence of flavonoids, triterpenoids, steroids and alkaloids in the methanol extract. The extract of n-hexane contained triterpenoids and alkaloids, while the chloroform extract contained flavonoids, triterpenoids and alkaloids. Keywords:  Euchema cottonii, antibacterial, disc diffusion
The Temperature and Time Influence of Immersion in Water Solvent against Formaldehyde Salted Level Belanak Fish (Mugil cephalus) Farid, Mohammad; Jannah, Akyunul; Maunatin, Anik
ALCHEMY ALCHEMY (Vol. 4, No.2
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (306.107 KB) | DOI: 10.18860/al.v4i2.3202

Abstract

The salted fish is one that is frequently consumed foods by the general public, but people do not realize that a lot of salted fish in the market that contained formaldehyde that can endanger the health of the body and is a food that is not suitable for consumption. The purpose of this study was to determine the temperature and the time required for formaldehyde in salted fish can be reduced. The formaldehyde method used to reduce level in foods, especially salted fish is by using immersion in water. Soaking dried fish is done by using variations in temperature and immersion time. Stage of the study was initiated with the addition of making salted fish with formalin at a concentration of 4%. The fish used is fresh mullet. Variations in temperature used is 40°C, 50°C,  60°C, and 70°C while the variation of time used is 10, 15, 20 and 25 minutes. The level of formaldehyde was analyzed by acid kromatofat and UV-Vis. The analysis results of formaldehyde levels using UV-Vis is the best temperature to reduce levels of formaldehyde in salted fish is 70 ° C by 80.2% and the best time to reduce levels of formaldehyde that is 25 min for 95.6%. Test statistics using Minitab ANOVA variance variant which shows that the influence of the decreased levels of formaldehyde salted fish and produce temperature and the best time is at a temperature of 70 °C and 25 minutes at a time. Keywords: Mugil chepalus, formaldehyde, salted fish, water solvent
Therapy Effect of Ethanol Extract of Binahong Tuber on Superoxide Dismutase (SOD) of Kidney of Rat Induced by Alloxan Ummah, Silviana Maslakhatul; Hasanah, Hafidatul
ALCHEMY ALCHEMY (Vol. 4, No.2
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (306.107 KB) | DOI: 10.18860/al.v4i2.3201

Abstract

Binahong (Anredera cordifolia (Ten.)Steenis) tuber is one of the plant that is not utilized yet for medicine. The aims of this research are to extract Binahong tuber  and determine superoxide dismutase (SOD) activity of kidney of rat (RattusNorvegicus) induced by Aloxsan. Extraction of binahong tuber was conducted by maceration method using 70% ethanol. The ethanol extract was used for therapy of Rat induced by Aloxsan and to determine SOD activity. Measuring of SOD kidney activity was conducted on 6 group of rat are D1 (control), D2 (0,5 % CMC-Na, dose 1 mL/200 g body weight), D3 (aloxsan 32 mg/200g body weight), D4, D5, D6 (aloxan 32 mg/kg body weight with therapy. Doses of extract binahong tuber were 25, 50 and 75 mg/kg body weight, respectively.The results showed that therap y of 70 % ethanol extract of Binahong tuber could increase the SOD activity of rat kidneys. But, after analyzed by ANAVA one way, the therapy did not give a real effect with value of α0,05 (0,1290,05). Duncan test showed that there was significant difference between D3 and D4. So the effective dose was 25 mg/kg body weight. Phytochemical test showed that ethanol extract of binahong tuber contained alkaloid, flavonoid, saponin, tanin and terpenoid. Keywords: Tuber of Anredera cordifolia (Ten.) Steenis, Superoxide Dismutase, Alloxan
Cation Exchange Capacity of Zeolite X from Bagasse Ash against Magnesium(II) Amalia, Suci
ALCHEMY ALCHEMY (Vol. 4, No.2
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (190.529 KB) | DOI: 10.18860/al.v4i2.3200

Abstract

Water is a substance crucial for human life and industries. The good water must be fulfill some criteria, such as absence of Ca2+ or Mg2+ cations. The cations can be reduced by ion exchange process. This study used synthesized zeolite X from bagasse ash as cation exchange for Mg2+. Mg ion was used as standard to determine hardness of water by EDTA titration. The analysis showed cation exchange capacity of zeolite X with molar ratio of  Si/Al 1; 1,5 and 2 was 1,9. The value indicated zeolite X have high capability as cation absorbents for Mg2+ ion. Keywords: bagasse ash, cation exchange capacity, magnesium(II), water hardness, zeolite X
Extraction, Toxicity Assay and Identification of Active Compounds of Red Algae (Eucheuma cottonii) from Sumenep Madura Afif, Sholeh; Fasya, Ahmad Ghanaim; Ningsih, Rachmawati
ALCHEMY ALCHEMY (Vol. 4, No.2
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (287.673 KB) | DOI: 10.18860/al.v4i2.3199

Abstract

Extraction, Toxicity Assay and Identification ofActive Compounds of Red Algae Extract (Eucheuma cottonii) from Tanjung Sumenep Madura was analysed. Extraction of active compound was conducted by maceration method  using methanol as a solvent. The methanol extract was hydrolyzed with HCl 2 N. The result was partitioned using five solvents (1-butanol, ethyl acetate, chloroform, petroleum  ether and n-hexane). Toxicity level was determined by Brine Shrimp Lethality Test (BSLT). The identification of the active compound was analyzed by phytochemical test, qualitatively. The result showed that the 1-butanol is the best solvent to extract active compounds of red algae E. Cottonii in partition process. 1-Butanol fraction gives the highest activity of toxicity with LC5070,32 ppm. LC50 value for ethyl acetate, chloroform, petroleum ether and n-hexane was 143,43; 194,40; 195,28; 303,66; and 634,97 ppm, respectively. Identification of active compounds indicated that 1-butanol fraction contains steroids and alkaloids. Keywords: Eucheuma cottonii, extraction, Brine Shrimp Lethality Test, phythochemical

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