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Althea Medical Journal
Published by Universitas Padjadjaran
ISSN : -     EISSN : 23374330     DOI : 10.15850/amj
Core Subject : Health,
Medicine & Pharmacology
Althea Medical Journal (AMJ) is a peer reviewed electronic scientific publication journal which is published every 3 months (March, June, September, and December). Althea Medical Journal publishes articles related to research in biomedical sciences, clinical medicine, family-community medicine, and public health.
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Articles 60 Documents
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Search results for , issue "Vol 3, No 4 (2016)" : 60 Documents clear
Electrocardiogram Profile in Children with Dengue Infection at Dr. Hasan Sadikin General Hospital and Bandung City Hospital Sakinah Binti Shabbir Hussain; Rahmat Budi Kuswiyanto; Januarsih Iwan
Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Dengue is a mosquito-borne infection which causes many manifestations on the organs, mainly heart. According to the histopathological analysis in heart, there is a direct action of dengue virus towards myocardium. This study was an initial study of cardiac involvement in dengue infection using electrocardiogram as a measurement tool. Methods: This study was a descriptive cross-sectional study and data collection were performed consecutively. A total of 17 children was taken which had been diagnosed with dengue infection according to World Health Organization criteria and had fulfilled inclusion and exclusion criteria of this study in Dr. Hasan Sadikin General Hospital and Bandung City Local Hospital. Once informed consent was obtained, the electrocardiogram procedure was performed according to standard electrocardiogram procedure in pediatrics. Data were analyzed by a pediatric cardiology consultant. Data were interpreted based on the electrocardiogram characteristics according to the type of dengue infection.Results: P wave amplitude was getting shorter as the severity of dengue infection increased. P wave duration increased slightly with increased severity of dengue infection. There was a significant increase in PR interval as the severity of dengue infection increased. The same was also true for ST and QTc wave.Conclusions: The pattern of electrocardiogram profile in children with dengue infection were within normal range. [AMJ.2016;3(4):629–32] DOI: 10.15850/amj.v3n4.950
Five-Year Data of Clinical Characteristics and Laboratory Findings of Hospitalized Hemophilic Patients in Dr. Hasan Sadikin General Hospital Dina Marlina; Lelani Reniarti; Fifi Veronica
Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Hemophilia A has the highest incidence, more than 80% of 172.323 cases worldwide in 2012. It is stated that clinical characteristics of hemophilia A is worse than others, so it is required to prove and to know further about the clinical characteristics and severity likelihood in all hemophilic patients in order to prevent re-bleeding and re-injury and also for a better medical response.Methods: A retrospective cross-sectional study was carried out to 43 medical records of hospitalized hemophilic patients from 2009 to 2013 in Dr Hasan Sadikin General Hospital. The inclusion criteria were a complete patient identity (name, age, sex), written chief complaint, complete physical examination (bleeding, edema, hematoma, hemarthrosis, anemic symptoms) and laboratory test results (factor level, hemoglobin, hematocrit, platelet and Activated Partial Thromboplastin Time). The data was collected from August‒October 2014, analyzed and presented using frequency distribution.Results: Most of the patients were 5-10 years old, male and had hemophilia A. The most common complaint was external bleeding, followed by edema. From 43 patients, 38 (88%) cases were classified as severe factor deficiency, had mild to severe anemia, however the platelet count in most of the cases was in normal value. About 91% cases had prolonged Activated Partial Thromboplastin Time in moderate to severe level.Conclusions: Similar with other studies worldwide, most of the hospitalized hemophilic patients have hemophilia A. Most of the patents has moderate to severe bleeding with laboratory test result between moderate to severe level as well. [AMJ.2016;3(4):605–9]
Five Years Data of Clinical and Histopathological Characteristics of Skin Adnexal Tumors in Dr. Hasan Sadikin General Hospital Bandung Jessica Oktavianus Trisaputra; Hermin Aminah Usman; Reti Hindritiani
Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Skin adnexal tumors arise from skin adnexal differentiation. Very limited number of study has been performed on their clinical and histopathological characteristics in Dr. Hasan Sadikin General Hospital. The objectives of this study was to identify the clinical and histopathological characteristic of skin adnexal tumors during the period of 2009 to 2013.Methods: AA descriptive study performed on 79 medical records of patients with skin adnexal tumors at the Department of Anatomic Pathology in Dr. Hasan Sadikin General Hospital Bandung from 2009 to 2013. Data were collected during the period of September to October 2014. The inclusion criteria were medical records containing information on skin adnexal tumors confirmed by histopathological examination results, patient characteristics (age and gender), and the tumor characteristics (size, location, malignancy, type, and histopathological origin). Collected data were processed using computer and presented in tables.Results: This study showed that tumors occured during productive age with male to female ratio was 1.2:1. Most skin adnexal tumors were ≤5 cm in size and were distributed in the head-neck region. Most of the tumors were benign and arised from hair follicle differentiation with pilomatricoma type while the malignant tumors commonly arised from sebaceous gland differentiation with sebaceous carcinoma type.Conclusions: Most skin adnexal tumors occur in productive age with no gender prediclation. They are small in size and are distributed in the cephalic region. Most are benign tumors arising from hair follicle differentiation with some malignant tumors arising from sebaceous gland differentiation. [AMJ.2016;3(4):514–9] DOI: 10.15850/amj.v3n4.933
Effectiveness of Allergic Rhinitis Management Related to WHO Guideline on Allergic Rhinitis and Its Impact on Asthma (ARIA) Atika Aziza; Arif Dermawan; Vycke Yunivita Kusumah Dewi
Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: The standard procedure of Allergic Rhinitis (AR) Management in Indonesia is based on Allergic Rhinitis and Its Impact on Asthma (ARIA) World Health Organization (WHO) 2008 guideline; however, it needs some adjustment to get an effective use locally in Indonesia. The data related to the problem however did not exist in Indonesia. The study aimed to evaluate the effectiveness of AR patient management based on the ARIA WHO guideline in the Department of Otorhinolaryngology-Head and Neck Surgery Dr. Hasan Sadikin General Hospital Bandung.Methods: The study was conducted from September to October 2015 using quantitative descriptive design to observe the development of ARIA classification, total nasal symptom score (TNSS), and quality of life (QoL) during the first 6 months of therapy. The data were obtained from medical records of AR patients who visited the Rhinology-Allergy clinic Department of Otorhinolaryngology-Head and Neck Surgery Dr. Hasan Sadikin General Hospital within one year. Thirty three patients were included in the study using total sampling.Results: There was significant improvement (p<0.001) in ARIA classification, TNSS, and QoL between the initiation of therapy, the third, and the sixth month. In contrary, there was no significant difference in ARIA classification (p=0.109), TNSS (p=0.317), and QoL (p=1.000) between the third and the sixth month of therapy.Conclusions: Allergic rhinitis patient management based on the 2008 ARIA WHO guideline is effective. [AMJ.2016;3(4):538–44]Keywords: Allergic rhinitis, asthma, effectiveness, management DOI: 10.15850/amj.v3n4.651
Age Pattern at Menarche as Results from a Puberty Survey Naereintheni A/P Ganabathy; Anggraini Widjajakusuma; Dini Hidayat
Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Range age of menarche is 15 to 17 years old from 1950’s to 20th century. However, in the current generation, the menarche age ranges from 13 to 16 years old. The factors affecting the change in the age of menarche over time and individual variation are due to the genetic or environmental factors. This study was performed to determine age pattern at menarche in Jatinangor, Sumedang ,West Java, Indonesia.Methods: The data for this descriptive study was obtained from a puberty survey performed by faculty members of Faculty of Medicine Universitas Padjadjaran from April–September 2013 in Jatinangor, Sumedang, West Java. A total of 249 female respondents aged 11–70 years old were included in this study. The age and year onset of menarche was determined and analyzed using computer.Results: The range age of menarche in Jatinangor population from early 1963 until 2013 was 9–17 years old, with 0.8% (n=2) cases of precocious puberty in current generation (year onset of menarche, year 2004–2013). For the onset of menstruation, the current generation had a youngest age compared to the other older generations with a mean age of 12.28 years old. Furthermore, most of the respondents from the current generation reached menarche at the age of 12 years old (37.4%). Conclusions: The onset of menarche in current generation is earlier compared to the older generations with most of them reaching menarche at the age of 12 years old. [AMJ.2016;3(4):640–3] DOI: 10.15850/amj.v3n4.952
Predictor of Mortality in Acquired Immunodeficiency Syndrome Patients with Central Nervous System Opportunistic Infections Agustina Lestari; Sofiati Dian; Chrysanti Murad
Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Indonesia’s increase of acquired immunodeficiency syndrome (AIDS) cases is one of the fastest. Mortality cases of AIDS also increase per year. Central nervous system (CNS) opportunistic infection is one of the most likely manifestations on advanced stage of Human immunodeficiency virus (HIV)/AIDS patients. Common CNS opportunistic infections are toxoplasma infection and tuberculous meningitis (TBM). The study aimed to analyze the predictor of mortality in AIDS patients with CNS opportunistic infections.Methods: This study reviewed 151 medical records from AIDS patients with CNS opportunistic infection admitted to the Department of Neurology, Dr. Hasan Sadikin General Hospital Bandung from 2007-2012. This study was conducted from April to November 2013. Patients’ clinical manifestations (seizure, headache, altered consciousness), laboratory examination (CD4+ level count) and treatment history (antiretroviral or ART and cotrimoxazole) were collected. Chi-square and logistic regression test were used to determine the mortality predictor in patients.Results: Mortality rate was 37.7%. Clinical manifestations from patients were seizure 29.8%, altered consciousness 66.2%, and headache 88.7%. Patients had cotrimoxazole treatment 44.4% and 38.4% patients had ART. CD4+ level count data from 86 patients were obtained, 94% had CD4+ level count ≤200. Bivariate analysis showed altered consciousness had significant mortality predictor (Odd ratio (OR): 29.944; 95% Confidence interval (CI) 6.9–129.945; p<0,0). Multivariate analysis showed ART had highest predictive mortality value (OR: 2.968; 95% CI 1.236–7.126; p=0.015).Conclusions: Altered consciousness and no antiretroviral treatment are mortality predictors in AIDS patients with CNS opportunistic infections. [AMJ.2016;3(4):577–82] DOI: 10.15850/amj.v3n4.942
Clinical Characteristics and Side Effects of Multidrug Resistant Tuberculosis Therapy at Top Referral Hospital West Java Indonesia Rika Nurlaily Rahmawati; Emmy Hermiyanti Pranggono; Rovina Ruslami
Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: The efficacy of multidrug resistant tuberculosis (MDR TB) therapy is still being questioned. It has lesser quality, longer duration therapy and high toxicity level. This study was conducted to identify clinical characteristics and side effect of MDR TB therapy at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia as the top referral hospital in West Java. Methods: A retrospective descriptive study was performed to 142 medical records of MDR TB inpatient and outpatient at Dr. Hasan Sadikin General Hospital from January 2012–July 2013. Data was collected on October–November 2013. Data about clinical characteristics and side effects of MDR TB therapy were collected and was analyzed in the form of percentage.Results: From 142 patients, 96% had history of tuberculosis therapy. Eighty (56%) of them had positive acid fast bacilli (AFB) sputum that still remained after 5th month or more with category 2. Seventy (49%) patients used combination of pyrazinamide, capreomycin, levofloxacin, ethionamide and cycloserine (Pz-Cm-Lfx-Eto-Cs). All patients experienced side effects during therapy and the majority of them (91%) had gastroenteropathy and rheumatism. Tentamen suicide was detected in one patient. Conclusions: The MDR TB patients had history of tuberculosis therapy. The majority of patients used combination of Pz-Cm-Lfx-Eto-Cs. All patients experienced side effects during MDR TB therapy. [AMJ.2016;3(4):526–32]
Profile and Behaviour of Mother as Factor of Increasing Diarrhea Incidence Children Under Five at Jatinangor District in 2013 Rahayu Widhyasti; Nita Arisanti; Ina Rosalina
Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: In 2012, data from Health Center of Jatinangor District showed nearly 50% of diarrhea cases occured in children under five at Sayang Village and Cilayung Village. Diarrhea cannot be separated from several factors that influence it, thus to reduce the incidence rate of diarrhea needs description of factors that affect diarrhea in children so that prevention can be done maximally. Objective of this study was to describe profile and behavior of mother as one factor of increasing diarrhea incidence in children under five at Jatinangor.Methods: This study was descriptive with cross-sectional design conducted at Sayang Village and Cilayung Village in October–November 2013. The respondents of this study were 102 mothers who have infants aged 0–59 months thorough cluster sampling methods. Respondent will be interviewed and given validated questionnaire. Results: The result showed that 57.8% of mother aged 25–35 years, mostly graduated from junior high education (41.2%), and 81.4% as a housewife. Most of diarrhea occurred in children under 2 years and female. There were 73.5% mother who exclusively breastfed, 94.1% have good behavior of clean water usage, 61.8% with good hand washing behavior, and 60.8% respondents utilized healthy latrine.Conclusions: This study showed good results in behaviour of exclusive breastfeeding, behavior of clean water usage, behaviour of hand washing with clean and water flow, and behaviour of healthy latrine usage. Other factors might be contributed to increasing diarrhea incidence. [AMJ.2016;3(4):655–60] DOI: 10.15850/amj.v3n4.956
Treatment Evaluation of Melasma Patients in Dr. Hasan Sadikin General Hospital Bandung in period of 2013–2014 Ayu Adzani Sabila; Reti Hindritiani; Dimas Erlangga Luftimas
Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Melasma is hyperpigmentation of the skin especially located on face exposed to the sunlight. This condition was characterized by brown to gray-brown macula with irregular border. Difficulties in treatment of melasma arise from high tendency for relapse, expensive cost, and high risk of side effects such as erythema, sores, scales, and acne eruption. Study about evaluation of melasma therapy in Dr. Hasan Sadikin General Hospital Bandung have not ever been done before. Therefore, this study was conducted to evaluate therapy of melasma in the Policlinic of Dermatology and Venereology, Dr. Hasan Sadikin General Hospital Bandung.Methods: This study was retrospectively descriptive. Data were obtained from the new melasma patient medical records of Policlinic of Dermatology and Venereology of Dr. Hasan Sadikin General Hospital Bandung in period of January 2013–2014. Sampling method used in this study was total sampling. Treatments of melasma were evaluated by using Melasma Area Severity Index (MASI) score. Collected data were processed and presented in frequency distribution and percentage.Results: The most used topical drugs were combination of hydroquinone and tretinoin, and all of patients received sunblock. Most frequent time interval was two weeks (30.8%). The most common side effect was erythema (10 out of 22). Decreased MASI score was discovered in 48.1% and the most decreased category was mild (14 out of 25). Conclusions: The very common topical drugs used are hydroquinone and tretinoin. The side effect of the treatment is Erythema. The decreased MASI score is mild. [AMJ.2016;3(4):610–5]DOI: 10.15850/amj.v3n4.947
Clinical and Histopathological Characteristics of Psoriasis in Dr. Hasan Sadikin General Hospital Bandung from 2009 to 2013 Willy Chandra Hermawan; Hermin Aminah; Dendi Sandiono
Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Psoriasis is a chronic inflammatory skin disease characterized by alterations in epidermal growth and differentiation. Its primary cause remains unknown, and its clinical and histopathological characteristics sometimes change from time to time. The study aimed to reveal the clinical and histopathological characteristics among psoriasis patients in Dr. Hasan Sadikin General Hospital Bandung.Methods: This study involved 162 medical records of psoriasis patients who visited the Department of Dermato-Venereology and 40 medical records of psoriasis patients who visited the Department of Pathological Anatomy of Dr. Hasan Sadikin Hospital, from 2009 to 2013. Medical record data were collected to describe the patient’s clinical and histopathological characteristics of psoriasis. The collected data were analyzed by frequency distribution.Results: From the clinical medical records, the characteristics found among the psoriasis patients were: 14 (8.6%) having familial history, 160 (98.8%) having reddish plaque, 155 (95.7%) having silvery scale, 40 (24.7%) having pustules, 6 (3.7%) having positive Auspitz sign, 48 (29.6%) having nail involvement, and 20 (12.4%) having tongue involvement. In addition, from the histopathological medical records, the characteristics of epidermis among the psoriasis patients found were: 36 (90%) having hyperkeratosis with parakeratosis, 39 (98%) having rete ridge elongation and/or acanthosis, 35 (88%) having Munro’s microabcess and/or micropustules of Kogoj, 15 (38%) having thin stratum granulosum, and 30 (75%) having blood vessels dilatation.Conclusions: In psoriasis, the most common clinical characteristics are reddish plaque while the most common histopathological characteristics are elongation of the rete ridges and/or acanthosis. [AMJ.2016;3(4):556–61] DOI: 10.15850/amj.v3n4.938

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