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Journal of Medical Physics and Biophysics
ISSN : 23552727     EISSN : 23552719     DOI : -
Core Subject : Health, Science,
Journal of Medical Physics and Biophysics is a gold open-access journal and serves as official publication media of the Indonesian Association of Physicists in Medicine, IAPM (Aliansi Fisikawan Medik Indonesia, AFISMI). JMPB publishes articles with the general concern on the application of physics in medicine and the biological system. The role of physics highlighted in the journal can be of theoretical, experimental, or clinical nature. Review and original articles in radiation oncology, diagnostic and interventional radiology, nuclear medicine, biomaterial, physical biology, physical modeling of biological system, and other related sciences are welcome. Any opinions stated on the articles published in JMPB are those of the author(s) and do not necessarily reflect the policy of IAPM/AFISMI unless otherwise stated.
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Articles 7 Documents
Search results for , issue "Vol 4, No 1 (2017)" : 7 Documents clear
Rejuvenating scientific culture in Indonesian medical physicists and biophysicists: the role of Journal of Medical Physics and Biophysics Supriyanto Ardjo Pawiro
Journal of Medical Physics and Biophysics Vol 4, No 1 (2017)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

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Abstract

Scatter index measurement using a CT dose profiler Choirul Anam; Freddy Haryanto; Rena Widita; Idam Arif; Toshioh Fujibuchi; Takatoshi Toyoda; Geoff Dougherty
Journal of Medical Physics and Biophysics Vol 4, No 1 (2017)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

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Abstract

The CT dose index (CTDI) is usually measured using a pencil chamber with a length of 100 mm on a CTDI phantom with a length of 150 mm. The scattering radiation dose beyond 100 mm is usually still significant despite using a small beam width (below 10 mm). This study aims to measure the scattering index of CT dose for several variations of input parameters. The scatter index measurements were performed on a multi-slice CT (MSCT) Alexion™ using a CT dose profiler detector connected to a Black Piranha electrometer (RTI Electronic, Sweden). The measurements used the helical mode and a beam width of 2 x 4 mm, and resulted in 150 mm dose profiles. Values of CTDI150, CTDI130 and CTDI100 were calculated and used to obtain values of the scatter indices (SI130 and SI150). We varied input parameters, such as tube voltage, tube current, and pitch, and used two types of CTDI phantoms, i.e. body and head. In the tube voltage variation (from 80 to 135 kV), we found SI130 and SI150 values of 1.13 ± 0.01 and 1.19 ± 0.01 for the body CTDI phantom; and  SI130 and SI150 values of 1.08 ± 0.01 and 1.11 ± 0.01 for the head CTDI phantom. For tube current variations from 25 to 120 mA, and pitch variations from 0.75 to 1.5, SI130 and SI150 values were 1.14 ± 0.00 and 1.20 ± 0.00 for the body CTDI phantom; and 1.08 ± 0.00 and 1.11 ± 0.00 respectively for the head CTDI phantom. We showed that the more frequently used CTDI100 value is too small because it ignores scattering beyond the 100 mm boundary, even for beam widths less than 10 mm. The scatter index values were strongly influenced by the size of the CTDI phantom, and were slightly affected by the tube voltage. Variations in tube currents and pitch did not affect the value of the scatter index. The scatter index values of SI130 and SI150 were significantly different, and suggests that the use of SI150 is even more appropriate for describing the scattering dose.
The effects of wound dressings on the dose at surface and depth of maximum dose (dmax) for photon and electron beam radiotherapy Raizulnasuha Binti Ab Rashid; Norhayati Dollah; Reduan Abdullah; Wan Nordiana W. Abd Rahman
Journal of Medical Physics and Biophysics Vol 4, No 1 (2017)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

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Abstract

The presence of wound dressing at the patients’ skin surface during radiotherapy treatment may potentially alter the dose at surface and shift the dose distribution at depth. In this study, the effects of different types of wound dressing to the radiotherapy treatment were investigated. The dose measurement at surface and dmax were done using different energy of photon and electron beams at 100 cm source to surface distance (SSD). Markus parallel plate ionization chamber and solid water phantom were used to quantify the dose with the dressing types used are Alderm +Plus, Actisorb Plus 25, Gauze and Duoderm CGF Extra Thin. The results show increment of surface dose up to 93.9% by wet gauze for photon beams and around 21% of dose increase for electron beams. Effects of dressing to the the dose at dmax indicate shift of dose distribution towards surface with reduction of dose around 10 % in wet condition for photon beam and up to 35 % for electron beams. Significant changes in surface dose and dose at dmax due to the wound dressing indicate the presence of wound dressing during radiotherapy need to taken in account in calculating dose to the target.
Radiation Dose Measurements at Radiosensitive Organs in Overcouch Barium Enema Examination Farah Mardhiah Janudin; Akmal Sabarudin; Khadijah Mohamad Nassir
Journal of Medical Physics and Biophysics Vol 4, No 1 (2017)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

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Abstract

The objectives of this study were to measure the radiation dose on the skin surface at the selective radiosensitive organs and to compare its distributions on an anthropomorphic phantom during an overcouch barium enema examination. This study was also designed to suggest the suitable exposure parameters for the projections in overcouch barium enema examination. The eye lens, thyroid, breast, and gonad were selected in this study and the dose was measured using thermoluminesence dosimeters (TLD) with computed radiography system. Five radiographic projections were carried out including supine, prone, right lateral decubitus, left lateral decubitus, and prone-angled view (Hampton’s view) to demonstrate the entire lower gastrointestinal tract. The highest skin surface dose (SSD) was received at the gonad followed by breasts, lens, and thyroid, corresponding to 2.49 ± 1.32 mGy, 0.14 ± 0.08 mGy, 0.057 ± 0.032 mGy, and 0.044 ± 0.04 mGy, respectively. The exposure parameters for tube voltage in a range of 75 kVp to 80 kVp, and tube current between 36 mAs and 40 mAs can provide proper image quality for abdominal region for an individual with average body weight.
Injectable Bone Substitute Synthesized from Mangrove Snail Shell Yessie Widya Sari; Reza Pahlevi Rudianto; Nur Aisyah Nuzulia; Sulistioso Giat Sukaryo
Journal of Medical Physics and Biophysics Vol 4, No 1 (2017)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

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Abstract

The need for biomaterials tends to increase especially in the field of medicine caused by cases of increasing bone damage. The biomaterial that is being developed for bone implants is hydroxyapatite (HAp). The high value of imports of bone-replacement biomaterials in Indonesia is conidered as a thoughtful problem because of the high price, therefore the development of biomaterials used as a substitute for bone derived from natural materials. In this study, HAp in the form of an injectable bone substitute (IBS) was syntehsized. IBS is a bone-substitute material in the form of a suspension. IBS can be applied by injection to reach deeper areas of bone defects and be able to adjust the shape of bone or tooth defects properly. HAp was synthesized in this study with assistance of microwave irradiation. Mangrove snail shell was used as calcium sources. Furthermore, this study indicated that HAp synthesized from mangrove snail shell had a high potency to be developed as IBS.
Computer Aided Diagnosis (CAD) for mammography with Markov Random Field method with Simulated Annealing optimization Ni Larasati Kartika Sari; Prawito Prajitno; Lukmanda Evan Lubis; Djarwani Soeharso Soejoko
Journal of Medical Physics and Biophysics Vol 4, No 1 (2017)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

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Abstract

Mammography is the most effective technique to detect breast abnormalities. In most cases, mammograms are evaluated by radiologists. However, diagnosis performed radiologist has a lot of limitations. Computer Aided Diagnosis (CAD) with various methods had been developed to help radiologist in evaluating mammograms. This research developed CAD for mammography based on image segmentation using Markov Random Field with Simulated Annealing optimization (MRF/SA). We combined MRF/SA method with various preprocessing algorithms, such as median filter, histogram equalization, and CLAHE (Contrast Limited Adaptive Histogram Equalization). MRF/SA without any filter and contrast enhancement was also performed. A total of 210 mammograms with normal and abnormal findings were used. Abnormal category means mammogram with abnormalities findings whether in a form of benign lesion, malignant lesion, benign microcalcification or malignant microcalcification. ROC (Receiver Operating Characteristic) analysis was used to measure methods’ performance. The values of area under the ROC curve (AUC) for MRF/SA only, median filter + MRF/SA, histogram equalization + MRF/SA and CLAHE + MRF/SA are 0.731, 0.840, 0.798, and 0.746 respectively. Combination of median filter + MRF/SA has the highest AUC value indicated that this method has the best performance in distinguishing normal and abnormal images. Histogram equalization + MRF/SA has inferior AUC value compare to median filter + MRF/SA, but this combination has the highest sensitivity, 90.4%. This result shows that histogram equalization + MRF/SA is the most successful method in detecting abnormal images correctly.
Setup uncertainty of head and neck cancer (HNC) patients treated with Image Guided and Intensity Modulated Radiotherapy (IG-IMRT) Nada Alia M Zamri; Hafiz M Zin
Journal of Medical Physics and Biophysics Vol 4, No 1 (2017)
Publisher : Indonesian Association of Physicists in Medicine (AIPM/AFISMI)

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Abstract

Advances in radiotherapy technology has made it possible to deliver highly conformal beams such as Intensity Modulated Radiotherapy (IMRT). The treatment is often guided by on-board cone-beam CT (CBCT) imaging system known as Image Guided Radiotherapy (IGRT). This retrospective study investigates the reproducibility of treatment setup for 25 head-and-neck cancer (HNC) patients underwent IMRT treatment at a new centre using kiloVoltage CBCT based-IGRT. All patients were immobilised using the HeadSTEPTM iFRAME. The planning target volume (PTV) margin was set to 3 mm for all directions during treatment planning. The pre-treatment CBCT imaging was acquired after patient setup. The treatment setup was corrected using online correction protocol for any errors ≥ 3 mm. 231 pre-treatment CBCT scans were acquired and setup errors were recorded in left-right (LR), anterior-posterior (AP) and superior-inferior (SI) directions. The treatment setup error of ≥ 3 mm occurred in 2.2% of measurements in LR direction, 1.7% in AP direction and 6.5% in SI direction. A PTV margin of 2.96 mm, 2.55 mm and 3.30 mm in RL, AP and SI directions, respectively was calculated using Van Herk formula, when no online corrections were performed. After online correction protocol, there were no more setup errors ≥3 mm in all three directions. The PTV margin was reduced to 2.53 mm (LR), 2.39 mm (AP) and 2.81 mm (SI). Therefore, CBCT-based online correction improves the accuracy of IMRT for HNC and reduces irradiated margin by reducing both systematic and random errors.

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