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INDONESIA
Jurnal Kesehatan Andalas
Published by Universitas Andalas
ISSN : 23017406     EISSN : 26151138     DOI : -
Core Subject : Health,
Health Professions
Jurnal Kesehatan Andalas merupakan Jurnal yang diterbitkan oleh Fakultas Kedokteran Universitas Andalas.
Arjuna Subject : -
Articles 1,294 Documents
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Perbandingan skor SOFA pada pasien sepsis dengan dan tanpa diabetes melitus tipe 2 Nares Wari, Munsyi; Fadrian; Yerizel , Eti; Reza , Mohamad; Aprilia , Dinda; Nofita , Eka
Jurnal Kesehatan Andalas Vol. 15 No. 1 (2026): March 2026
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v15i1.2672

Abstract

Comparison of SOFA scores in septic patients with and without type 2 diabetes mellitus Sepsis is a life-threatening organ dysfunction.  A dysregulated host response to infection causes it. Organ dysfunction can be represented by an increase in the SOFA score of > 2 points. Every increase in the score reflects worsening of organ dysfunction. Type-2 Diabetes Mellitus (T2DM) is one of the most common comorbidities in sepsis patients. T2DM patients have chronic hyperglycemia. This condition can impair immune function and damage the endothelium.  Objective: To find out the comparison of SOFA scores in sepsis patients with and without T2DM. Methods: This research was an analytical, cross-sectional study using medical record data from RSUP Dr. M. Djamil Padang. The 132 samples comprised 66 sepsis patients with T2DM and 66 without T2DM. Sampling was carried out by using a stratified random sampling technique. Bivariate data analysis used an independent-samples t-tes. The mean of SOFA scores in sepsis patients with T2DM was 8.05 +_ 2.36 and the mean of SOFA scores in sepsis patients 6.38 +_ 2.96. The p-value (<0,05) in both groups was 0.001. Conclusion: There is a significant difference in SOFA scores between sepsis patients with and without T2DM. Keywords: sepsis, SOFA score, T2DM
Strategi pencegahan non-farmakologis pada rhinitis alergi dalam mengatasi keterbatasan terapi antihistamin jangka panjang: Systematic review Adji, Iwan Setiawan; Ristyana, Sabira Husna; Mahensa, Noval Gentha; Anggrahini, Witrishya; Nabilah, Aisyah; Nadhifa, Marshanda Ariella; Fatimah, Lina Nur; Nadzifa, Dhia Laila
Jurnal Kesehatan Andalas Vol. 15 No. 1 (2026): March 2026
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v15i1.2685

Abstract

Non-pharmacological prevention strategies for allergic rhinitis in addressing the limitations of long-term antihistamine therapy: A systematic review Antihistamine therapy in Allergic rhinitis is generally the primary choice for symptom management. However, long-term use often presents side effects such as sedation, tolerance, and lack of control over allergen exposure. Non-pharmacological preventive strategies are important to explore as complementary and alternative approaches. Objective: To analyze effective non-pharmacological strategies for the prevention of allergic rhinitis. Methods: A literature search was conducted across electronic databases such as PubMed, Scopus, and Google Scholar, focusing on publications published between 2015 and 2024. The selected studies included experimental studies, systematic reviews, and clinical guidelines addressing non-pharmacological interventions for allergic rhinitis. The most frequently discussed non-pharmacological strategies included environmental controls (e.g., reducing exposure to dust, mites, and air pollution), nasal saline irrigation, mask use, lifestyle modifications, and patient education. Results: Several interventions have shown significant reductions in symptom scores and improvements in patients' quality of life, especially when combined with pharmacological therapy. Non-pharmacological approaches have significant potential as long-term management strategies for allergic rhinitis. Conclusion: The combination of education, environmental modifications, and physical interventions can reduce symptom frequency and the need for antihistamines. Keywords: allergic rhinitis, antihistamines, environmental modifications, non-pharmacological, prevention
Peran stres oksidatif dalam hipertensi esensial: Systematic review Arban, Nur Ramadani; Zulkarnain, Mohammad; Novita, Emma
Jurnal Kesehatan Andalas Vol. 15 No. 1 (2026): March 2026
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v15i1.2706

Abstract

The role of oxidative stress in essential hypertension: A systematic review Oxidative stress plays a crucial role in the pathogenesis of essential hypertension. It leads to endothelial dysfunction, reduced nitric oxide (NO) bioavailability, and increased arterial stiffness, all of which contribute to elevated blood pressure. Objective: To analyze the role of oxidative stress in the pathogenesis of essential hypertension. Methods: This study was a literature review conducted by searching PubMed, ScienceDirect, and Cochrane databases from 2021 to 2025 using the keywords “Hypertension AND Oxidative Stress AND Correlation.” Of the 2700 identified articles, six studies met the inclusion and exclusion criteria and were analyzed further. Results: All selected studies demonstrated a strong relationship between oxidative stress and hypertension. Increased production of Reactive Oxygen Species (ROS) impairs endothelial function, reduces NO levels, and increases arterial stiffness. Interventions using antioxidants, such as melatonin, and dietary nitrates improved vascular function and oxidative balance. However, the outcomes varied depending on the type and dosage of antioxidants used. Conclusion: Oxidative stress plays a key role in the development of essential hypertension through endothelial damage, vascular dysfunction, and activation of the renin-angiotensin system. Antioxidant-based interventions, particularly melatonin, show promising potential to improve redox balance and reduce blood pressure. Further studies are needed to establish their long-term efficacy and safety. Keywords:  antioxidants, essential hypertension, oxidative stress, melatonin, nitric oxide  
Hubungan tingkat pendidikan, status pekerjaan, dan perbedaan rerata asupan makanan ibu hamil: Studi cross-sectional pada ibu hamil di Provinsi Sumatera Barat Dwinanda Ralni, Fristy; Lipoeto, Nur Indrawati; Fadila, Zurayya
Jurnal Kesehatan Andalas Vol. 15 No. 1 (2026): March 2026
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v15i1.2720

Abstract

Relationship between education level, employment status, and differences in average food intake among pregnant women: A cross-sectional study on pregnant women in West Sumatra Province A pregnant woman will experience weight gain. Many factors influence weight gain in pregnant women, such as level of education, employment status, and food intake. Objective: To determine the relationship between education level, employment status, and variations in average dietary intake on weight gain among pregnant women. Methods: A cross-sectional study was conducted in West Sumatra Province with 183 respondents. Data on pregnant women's weight, employment status, education level, and food intake were obtained from secondary data sources, including maternal weight measurements, sociodemographic data, and the SQ-FFQ. The analysis uses the Chi-square test and one-way ANOVA. Results: The relationship between education level and employment status with weight gain of pregnant women were obtained with values of p=0.661 and p=0.977, and the difference between the average food intake (energy, carbohydrates, protein, and fat) with the weight gain of pregnant women was obtained sequentially, with values of p=0.179, 0.568, 0.143, and 0.104. Conclusion:  There was no significant relationship between job status and education level and weight gain of pregnant women, and there was no significant average difference between food intake and weight gain of pregnant women. Keywords: education level, employment status, food intake, pregnancy weight gain

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