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INDONESIA
Jurnal Kesehatan Andalas
Published by Universitas Andalas
ISSN : 23017406     EISSN : 26151138     DOI : -
Core Subject : Health,
Health Professions
Jurnal Kesehatan Andalas merupakan Jurnal yang diterbitkan oleh Fakultas Kedokteran Universitas Andalas.
Arjuna Subject : -
Articles 1,300 Documents
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Perbandingan skor SOFA pada pasien sepsis dengan dan tanpa diabetes melitus tipe 2 Munsyi Nares Wari; Fadrian; Eti Yerizel; Mohamad Reza; Dinda Aprilia; Eka Nofita
Jurnal Kesehatan Andalas Vol. 15 No. 1 (2026): March 2026
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v15i1.2672

Abstract

Comparison of SOFA scores in septic patients with and without type 2 diabetes mellitus Sepsis is a life-threatening organ dysfunction.  A dysregulated host response to infection causes it. Organ dysfunction can be represented by an increase in the SOFA score of > 2 points. Every increase in the score reflects worsening of organ dysfunction. Type-2 Diabetes Mellitus (T2DM) is one of the most common comorbidities in sepsis patients. T2DM patients have chronic hyperglycemia. This condition can impair immune function and damage the endothelium.  Objective: To find out the comparison of SOFA scores in sepsis patients with and without T2DM. Methods: This research was an analytical, cross-sectional study using medical record data from RSUP Dr. M. Djamil Padang. The 132 samples comprised 66 sepsis patients with T2DM and 66 without T2DM. Sampling was carried out by using a stratified random sampling technique. Bivariate data analysis used an independent-samples t-tes. The mean of SOFA scores in sepsis patients with T2DM was 8.05 +_ 2.36 and the mean of SOFA scores in sepsis patients 6.38 +_ 2.96. The p-value (<0,05) in both groups was 0.001. Conclusion: There is a significant difference in SOFA scores between sepsis patients with and without T2DM. Keywords: sepsis, SOFA score, T2DM
Strategi pencegahan non-farmakologis pada rhinitis alergi dalam mengatasi keterbatasan terapi antihistamin jangka panjang: Systematic review Iwan Setiawan Adji; Sabira Husna Ristyana; Noval Gentha Mahensa; Witrishya Anggrahini; Aisyah Nabilah; Marshanda Ariella Nadhifa; Lina Nur Fatimah; Dhia Laila Nadzifa
Jurnal Kesehatan Andalas Vol. 15 No. 1 (2026): March 2026
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v15i1.2685

Abstract

Non-pharmacological prevention strategies for allergic rhinitis in addressing the limitations of long-term antihistamine therapy: A systematic review Antihistamine therapy in Allergic rhinitis is generally the primary choice for symptom management. However, long-term use often presents side effects such as sedation, tolerance, and lack of control over allergen exposure. Non-pharmacological preventive strategies are important to explore as complementary and alternative approaches. Objective: To analyze effective non-pharmacological strategies for the prevention of allergic rhinitis. Methods: A literature search was conducted across electronic databases such as PubMed, Scopus, and Google Scholar, focusing on publications published between 2015 and 2024. The selected studies included experimental studies, systematic reviews, and clinical guidelines addressing non-pharmacological interventions for allergic rhinitis. The most frequently discussed non-pharmacological strategies included environmental controls (e.g., reducing exposure to dust, mites, and air pollution), nasal saline irrigation, mask use, lifestyle modifications, and patient education. Results: Several interventions have shown significant reductions in symptom scores and improvements in patients' quality of life, especially when combined with pharmacological therapy. Non-pharmacological approaches have significant potential as long-term management strategies for allergic rhinitis. Conclusion: The combination of education, environmental modifications, and physical interventions can reduce symptom frequency and the need for antihistamines. Keywords: allergic rhinitis, antihistamines, environmental modifications, non-pharmacological, prevention
Peran stres oksidatif dalam hipertensi esensial: Systematic review Nur Ramadani Arban; Mohammad Zulkarnain; Emma Novita
Jurnal Kesehatan Andalas Vol. 15 No. 1 (2026): March 2026
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v15i1.2706

Abstract

The role of oxidative stress in essential hypertension: A systematic review Oxidative stress plays a crucial role in the pathogenesis of essential hypertension. It leads to endothelial dysfunction, reduced nitric oxide (NO) bioavailability, and increased arterial stiffness, all of which contribute to elevated blood pressure. Objective: To analyze the role of oxidative stress in the pathogenesis of essential hypertension. Methods: This study was a literature review conducted by searching PubMed, ScienceDirect, and Cochrane databases from 2021 to 2025 using the keywords “Hypertension AND Oxidative Stress AND Correlation.” Of the 2700 identified articles, six studies met the inclusion and exclusion criteria and were analyzed further. Results: All selected studies demonstrated a strong relationship between oxidative stress and hypertension. Increased production of Reactive Oxygen Species (ROS) impairs endothelial function, reduces NO levels, and increases arterial stiffness. Interventions using antioxidants, such as melatonin, and dietary nitrates improved vascular function and oxidative balance. However, the outcomes varied depending on the type and dosage of antioxidants used. Conclusion: Oxidative stress plays a key role in the development of essential hypertension through endothelial damage, vascular dysfunction, and activation of the renin-angiotensin system. Antioxidant-based interventions, particularly melatonin, show promising potential to improve redox balance and reduce blood pressure. Further studies are needed to establish their long-term efficacy and safety. Keywords:  antioxidants, essential hypertension, oxidative stress, melatonin, nitric oxide  
Hubungan tingkat pendidikan, status pekerjaan, dan perbedaan rerata asupan makanan ibu hamil: Studi cross-sectional pada ibu hamil di Provinsi Sumatera Barat Fristy Dwinanda Ralni; Nur Indrawati Lipoeto; Zurayya Fadila
Jurnal Kesehatan Andalas Vol. 15 No. 1 (2026): March 2026
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v15i1.2720

Abstract

Relationship between education level, employment status, and differences in average food intake among pregnant women: A cross-sectional study on pregnant women in West Sumatra Province A pregnant woman will experience weight gain. Many factors influence weight gain in pregnant women, such as level of education, employment status, and food intake. Objective: To determine the relationship between education level, employment status, and variations in average dietary intake on weight gain among pregnant women. Methods: A cross-sectional study was conducted in West Sumatra Province with 183 respondents. Data on pregnant women's weight, employment status, education level, and food intake were obtained from secondary data sources, including maternal weight measurements, sociodemographic data, and the SQ-FFQ. The analysis uses the Chi-square test and one-way ANOVA. Results: The relationship between education level and employment status with weight gain of pregnant women were obtained with values of p=0.661 and p=0.977, and the difference between the average food intake (energy, carbohydrates, protein, and fat) with the weight gain of pregnant women was obtained sequentially, with values of p=0.179, 0.568, 0.143, and 0.104. Conclusion:  There was no significant relationship between job status and education level and weight gain of pregnant women, and there was no significant average difference between food intake and weight gain of pregnant women. Keywords: education level, employment status, food intake, pregnancy weight gain
Depresi berhubungan dengan perilaku self management pasien hemodialisis di RSD KRMT Wongsonegoro kota Semarang (The depression is associated with self-management behavior among hemodialysis patients at RSD KRMT Wongsonegoro Semarang city) Zain Ramadhani; Merry Tiyas Anggraini; Nina Anggraeni Noviasari
Jurnal Kesehatan Andalas Vol. 15 No. 2 (2026): July 2026
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v15i2.2752

Abstract

Chronic Kidney Disease (CKD) requires hemodialysis therapy. It obliges patients to undergo complex and lifelong treatments, resulting in physical, psychological, and social limitations. Patients frequently experience depression, either at the time of diagnosis or during the course of therapy. To optimize quality of life and survival, self-management behaviors, such as active participation in self-care, are essential for achieving optimal health and preventing further complications during treatment. Objective: To determine the relationship between depression and self-management behavior among hemodialysis patients at RSD KRMT Wongsonegoro, Semarang city. Methods: This study employed a quantitative analytic observational design with a cross-sectional approach. The subjects were 50 hemodialysis patients at RSD KRMT Wongsonegoro, Semarang City, selected using a total sampling technique based on inclusion and exclusion criteria. Data were collected through interviews using the Hamilton Depression Rating Scale and the Hemodialysis Patient Self-Care Measurement Scale. The relationship between variables was analyzed using Spearman’s Rank correlation test. Results: The majority of respondents had normal levels of depression (25; 50%), and most had moderate levels of self-management (36; 72%). Spearman’s Rank test showed a significant relationship between depression and self-management among hemodialysis patients at RSD KRMT Wongsonegoro (p = 0.044; r = 0.286), indicating a weak correlation. Conclusion: There is a significant relationship between depression and self-management behavior among hemodialysis patients at RSD KRMT Wongsonegoro, Semarang City. Keywords: depression, hemodialysis, self-management
Terapi plasmaferesis pada penderita Sindrom Guillain-Barré: Sebuah tinjauan sistematis (Plasmapheresis therapy in patients with Guillain-Barré syndrome: A systematic review) Raisa Ainul Mardiyah; Restu Susanti; Rudy Afriant; Zelly Dia Rofinda; Reno Bestari; Almurdi
Jurnal Kesehatan Andalas Vol. 15 No. 2 (2026): July 2026
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v15i2.2765

Abstract

Plasmapheresis therapy is one of the treatment modalities for Guillain-Barré syndrome (GBS). However, this therapy poses significant challenges, particularly in Indonesia, due to its high cost and complex procedures. Objective: To describe the epidemiological characteristics of GBS patients, assess the indications, effectiveness, safety, and therapeutic responses of plasmapheresis among its variants. Methods: This systematic review was conducted by searching several databases for articles published between January 2020 and May 2025. Based on the established eligibility criteria, 10 articles were included for this review. Results: The majority of GBS patients were male, with a wide age range from 2 to 70 years old, and various GBS types. Most studies have indicated that plasmapheresis therapy significantly improved clinical outcomes in GBS patients, and that it was more effective when administered within 7–10 days of symptom onset. Plasmapheresis was also reported as a relatively safe therapy with tolerable side effects. However, GBS variants and the patient’s initial condition may influence the response to plasmapheresis therapy. Conclusion: Plasmapheresis therapy has been proven to provide meaningful clinical benefits for most GBS patients. Keywords:  efficacy, functional outcomes, Guillain-Barré syndrome, plasmapheresis, safety
Hubungan anemia defisiensi besi dengan risiko infeksi saluran kemih pada ibu hamil: Tinjauan sistematis (The association between iron-deficiency anemia and the risk of urinary tract infections in pregnant women: A systematic review) Kevin Aldenio Hatma Krista; Kehat Dowie Setiabudi Arrung; Christian Stephen Hutagalung; Theresia Avilla Ririel Kusumosih; Nur Budiono
Jurnal Kesehatan Andalas Vol. 15 No. 2 (2026): July 2026
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v15i2.2790

Abstract

Iron Deficiency Anemia (IDA) is one of the most common maternal health problems during pregnancy. It contributes substantially to maternal and fetal morbidity. Iron deficiency may impair maternal immune function, thereby increasing susceptibility to urinary tract infections (UTIs). Objective: To evaluate the association between IDA and the risk of UTIs among pregnant women. Methods: This study was developed in accordance with the PRISMA 2020 guidelines. A comprehensive literature search was conducted in PubMed/MEDLINE, Scopus, Google Scholar, and the Cochrane Library, targeting studies published between 2015 and 2025 using keywords related to iron deficiency anemia, pregnancy, and urinary tract infection. Article selection involved identification, title and abstract screening, and full-text eligibility assessment according to predefined inclusion and exclusion criteria. Eligible studies were analyzed narratively. Results: A total of 742 articles were identified during the initial search process, of which 7 studies met the inclusion criteria for final analysis. Most studies demonstrated that pregnant women with IDA had a higher risk of asymptomatic bacteriuria and UTIs compared with non-anemic pregnant women. Significant associations were reported between low hemoglobin levels and increased maternal UTI incidence. Additional factors influencing the occurrence of UTIs included gestational age, nutritional status, parity, and access to antenatal care services. Conclusion: IDA may increase the risk of UTIs through impaired maternal immune function and physiological alterations of the urinary tract during pregnancy. Keywords: asymptomatic bacteriuria, iron deficiency anemia, pregnancy, pregnant women, urinary tract infection
Hubungan derajat merokok dengan kejadian mata kering pada perokok aktif pria dewasa muda (Correlation between smoking intensity and the incidence of dry eye syndrome among young adult male active smokers) Reza Putra Bacthiar; Nika Bellarinatasari; Menik Sahariyani
Jurnal Kesehatan Andalas Vol. 15 No. 2 (2026): July 2026
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v15i2.2799

Abstract

Smoking is a lifestyle risk factor that disrupts ocular surface homeostasis through toxic exposure to the tear film and systemic effects on lacrimal gland function. Objective: To determine the association between smoking intensity and dry eye syndrome among young adult male active smokers. Methods: This analytic observational study employed a cross-sectional design and enrolled 65 subjects (130 eyes) from 297 male students at the Faculty of Medicine, Universitas Islam Sultan Agung. Smoking intensity was categorized into mild, moderate, and heavy. Clinical evaluation included the Ocular Surface Disease Index (OSDI) questionnaire, Tear Break-Up Time (TBUT) test, and Schirmer I test. Data were analyzed using the Chi-square test and Somers’d coefficient (p < 0.05). Results: The mean subject age was 20.02 ± 1.36 years. Dry eye syndrome affected 81 eyes (62.3%). A significant association was found between smoking intensity and dry eye syndrome (p < 0.001), with a moderate strength of association (d = 0.490). Dry eye occurrence increased with smoking intensity: 36.7% in the mild group, 83.3% in the moderate group, and 86.4% in the heavy group. Conclusion: Smoking intensity is significantly associated with dry eye syndrome among young adult male active smokers. Ocular surface disruption was found to worsen as smoking intensity increased. Practitioners should conduct routine screening and provide smoking cessation education from a young age. Comprehensive prevention is warranted, considering the mild group already exhibits a high incidence of dry eye. Keywords:  active smokers, dry eye syndrome, ocular surface, risk factor, smoking intensity
Analisis perencanaan strategis rumah sakit khusus bedah Ropanasuri tahun 2026–2030 (Strategic planning analysis of Ropanasuri specialized surgicalhospital for 2026–2030) Faris Muhammad; Rizanda Machmud; Nelmi Silvia
Jurnal Kesehatan Andalas Vol. 15 No. 2 (2026): July 2026
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v15i2.2802

Abstract

RSKB Ropanasuri has experienced a decline in service performance over the past two years, reflected by decreases in outpatient visits, surgical procedures, inpatient admissions, and bed utilization. Changes in the National Health Insurance (JKN) policy, digital transformation, technological advances, and increasing competition require the development of an adaptive strategic plan. Objective: To formulate the strategic plan for RSKB Ropanasuri for the 2026–2030 period. Methods: This qualitative descriptive study employed in-depth interviews, document reviews, observations, and the Consensus Decision Making Group (CDMG) approach. Strategic analysis was conducted using the Internal Factor Evaluation (IFE), External Factor Evaluation (EFE), SWOT, Internal–External (IE), and Quantitative Strategic Planning Matrix (QSPM). Results: The IFE score of 2.59 and EFE score of 2.63 positioned RSKB Ropanasuri in Cell V of the IE Matrix (hold and maintain). Priority strategies included organizational transformation and capacity development, enhancement of specialized surgical services, and diversification of non-JKN revenue sources. Conclusion: The 2026–2030 strategic plan focuses on strengthening internal capacity, expanding specialized services, and diversifying revenue to improve competitiveness, service quality, and long-term sustainability. Keywords: QSPM, specialized surgical hospital, strategic planning
Optimalisasi pengendalian tuberkulosis paru melalui pendekatan keluarga di puskesmas: Studi kasus Pesanggaran (Optimization of pulmonary tuberculosis control through a family-based approach at community health centers: A case study in Pesanggaran) Lilik Djuari; Ryan Sedjati Prakuswo; Eukesh Kumar Krishna Kumar; Edi Nurcahyo Safii; Komang Heru Setiawan; Abdullah Machin
Jurnal Kesehatan Andalas Vol. 15 No. 2 (2026): July 2026
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v15i2.2804

Abstract

A family-based approach has emerged as an important strategy for enhancing pulmonary tuberculosis (TB) control at the primary health care level. Objective: To examine the optimization of pulmonary tuberculosis control through a family-centered approach in the working area of Pesanggaran Primary Health Care, Banyuwangi. Methods: Data were collected through interviews, home observations, and assessments of environmental risk factors, health behaviors, and family support. The interventions provided included health education, improving medication adherence, improving home ventilation, and involving family members as treatment supporters (medication-taking supervisors/PMOs). Results: The results showed that a family-based approach was able to improve patients’ and families’ understanding of tuberculosis (TB), enhance treatment adherence, and reduce the risk factors for transmission within the home environment. Optimal family support contributed to treatment success and the prevention of complications. Conclusion: A family-based approach is effective in optimizing the control of pulmonary tuberculosis at the primary healthcare level. Integration of this approach into community health center (puskesmas) programs should be strengthened as a comprehensive strategy for TB control in the community. Keywords: family-centered approach, primary health care, pulmonary tuberculosis, treatment adherence

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