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INDONESIA
Jurnal Kesehatan Andalas
Published by Universitas Andalas
ISSN : 23017406     EISSN : 26151138     DOI : -
Core Subject : Health,
Health Professions
Jurnal Kesehatan Andalas merupakan Jurnal yang diterbitkan oleh Fakultas Kedokteran Universitas Andalas.
Arjuna Subject : -
Articles 1,282 Documents
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Perbedaan Derajat Adhesi Peritendinous Setelah Pemberian Platelet Rich Plasma (PRP) Terhadap Penyembuhan Ruptur Tendon Achilles Tikus Wistar Ananda, Gita Putri; Rahmadian, Rizki; Intan, Shinta Ayu; Rikarni, Rikarni; Rusjdi, Selfi Renita
Jurnal Kesehatan Andalas Vol. 14 No. 1 (2025): March 2025
Publisher : Faculty of Medicine, Universitas Andalas

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Abstract

Platelet-rich plasma (PRP) has been identified as a potential agent to enhance the tendon healing process and prevent complications such as adhesion and tendon displacement after surgery. Objective: To determined the difference in the degree of peritendinous adhesion after administration of platelet-rich plasma (PRP) on the healing of Achilles tendon rupture in Wistar rats. Methods: This study used a post-test only control group experimental design. Tendons in the control group were treated without PRP, while the treatment group received PRP before care. After one week, the degree of peritendinous adhesion was evaluated microscopically using the Tang scoring system. Results: The mean degree of adhesion in the control group was 3.38, and in the treatment group it was 3.83. The independent t-test yielded a non-significant value of 0.411 (p > 0.05). Conclusion: There was no significant difference in the degree of peritendinous adhesion in Achilles tendon rupture healing of Wistar rats between the group given PRP and the group not given PRP. Keywords: peritendinous adhesion, PRP, tendon rupture, Tang score
Ekstrak Cikal Tulang (Cissus quadrangularis) sebagai Alternatif Pencegahan Obesitas secara in Vivo: 29 - 34 Surya, Maria Angeline Ivana; Chandra, Magdalena Leony; Nathaniela, Jocelin; Dewi, Ni Wayan Sucindra
Jurnal Kesehatan Andalas Vol. 14 No. 1 (2025): March 2025
Publisher : Faculty of Medicine, Universitas Andalas

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Abstract

Cikal Tulang (Cissus quadrangularis) contains ketosteroids that can be used as a traditional obesity treatment. Objective: To evaluated the potential of Cikal Tulang (Cissus quadrangularis) extract in preventing obesity (loss of body weight and abdominal fat) in Galur Swiss mice. Methods: A quasi-experimental post-test only design was conducted from July to August 2021, involving 30 male Swiss albino mice aged 1.5 months with body weights of 18–30 grams. The mice were divided into five groups: negative control (high-fat diet and fructose solution), positive control (orlistat 15.6 mg/kgBW), and three treatment groups receiving Cissus quadrangularis extract at doses of 30, 90, and 180 mg/kgBW for 14 days. The extract was administered orally via a gastric sonde. Body weight and Lee index were obesity parameters, and abdominal adipose tissue was analyzed morphometrically using hematoxylin-eosin staining. Data were analyzed with One-Way ANOVA at a significance level of p < 0.05. Results: One-Way ANOVA test showed significant differences in Lee index among groups before treatment (p = 0.0097), with values >300 indicating obesity. Post-treatment, Lee index decreased across groups but without statistically significant differences (p = 0.878), with values remaining >300. Conclusion: There was no significant association between administering cikal tulang (Cissus quadrangularis) extract and its anti-obesity effect. Keywords:  anti-obesitas, cikal tulang (Cissus quadrangularis), fat

Page 129 of 129 | Total Record : 1282

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