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Research Journal of Life Science
Published by Universitas Brawijaya
ISSN : -     EISSN : 23559926     DOI : https://doi.org/10.21776/ub.rjls
Core Subject : Health, Science, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology
Research Journal of Life Science (RJLS) is an open access publishes papers three times a year that emphasize the agriculture, fisheries, animal science, medicine, basic science and food technology. All articles are rigorously reviewed by reviewers. Articles should be created in a language that is easily understood by non-specialist readers in the topic of the article itself, but interested in research. The main objective of RJLS is to provide a platform for the international scholars, academicians and researchers to share the contemporary thoughts and innovations in the field of life science. RJLS aims to promote studies in life science and so become the leading international journals in life science in the world.This journal intends to provide facilities to advance the development and application of interdisciplinary and transdisciplinary research methodologies in life sciences.
Arjuna Subject : Ilmu Pertanian dan Biologi (Semua) - Ilmu Pertanian dan Biologi (Lain-Lain)
Articles 5 Documents
 1 
Search results for , issue "Vol 6, No 3 (2019)" : 5 Documents clear
Active Compounds on Squid (Loligo sp.) Ink Extract Powder as Immunostimulant Candidate to Against Shrimp Disease Rangga Idris Affandi; Mohamad Fadjar; Arning Wilujeng Ekawati
Research Journal of Life Science Vol 6, No 3 (2019)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (485.685 KB) | DOI: 10.21776/ub.rjls.2019.006.03.1

Abstract

The business of developing shrimp farming cannot be separated from the existence of disease. In shrimp farming health management, disease prevention strategies can using various methods, one of which is immunostimulant. One alternative immunostimulant source that can be used to improve the body defense system in shrimp is squid (Loligo sp.) ink extract powder who has antibacterial ability. This study aims to analyze the presence of active compound in squid ink extract powder can be used as an immunostimulant candidate to against shrimp disease. The method used in this research is descriptive explorative and experimental method. This research was conducted with several stages of squid ink extraction until it becomes powder. Identification of squid ink extract powder is using FTIR and LC-MS test. The results showed that the squid ink extract powder contained alkaloid and carboxylic acid from the FTIR test results. Based on LC-MS test results, it was found that squid ink extract powder contained betaine, cinnamic acid, and choline compounds with large amounts of content. Betaine, cinnamic acid, and choline has several biological activity as antibacterial, antioxidant, antiviral, antifungal, etc. so that it can be used as an immunostimulant against shrimp disease.
Physical and Organlopetic Properties of Nuggets from Domestic Chicken (Gallus domesticus) Meat with Different Corn Flours as Filler Wahidah Ma'ruf; Djalal Rosyidi; Lilik Eka Radiati; Purwadi Purwadi
Research Journal of Life Science Vol 6, No 3 (2019)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (337.404 KB) | DOI: 10.21776/ub.rjls.2019.006.03.2

Abstract

The research aims to understand the physical and organoleptic properties of the Indonesian domestic chicken (Gallus domesticus) nugget made with different corn flours as filler. The research was done in two research steps. The first step was to observe the physical properties of the chicken nugget through a completely randomized design, where five different corn flours were used and measured for six times each. The second step was to observe the organoleptic properties of the chicken nugget through two-factorials completely randomized design, where five different panellists (P1, P2, P3, P4, and P5) were the first factor and different corn flours were the second factor. The corn flours used in this research were yellow-corn (J1); fluffy-corn (J2); purple-corn (J3); Provit A1-corn (J4); and Provit A2-corn (J5) flour. The measured variables include cooking loss, flavor, aroma, texture, and color of the chicken nugget. The results showed that J1 chicken nugget had the lowest cooking loss at 1.27%, while the organoleptic measurements showed that J4 chicken nugget had the best organoleptic properties. The research concluded that the usage of Provit A1-corn (J4) flour would give the best overall physical and organoleptic properties of chicken nugget made from domestic chicken meat.
Simulation of Tumor Growth Model and Its Interaction with Natural-Killer Cells and T Cells Cholifatul Maulidiah; Trisilowati Trisilowati; Ummu Habibah
Research Journal of Life Science Vol 6, No 3 (2019)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.rjls.2019.006.03.5

Abstract

This research studies about tumor growth model by involving immune system. Cells in the immune system, for instance natural killer (NK) cells and T cells, have prominent role in recognizing and eliminating tumor cells. In this paper, we construct the tumor growth model consisting of four populations namely tumor cells, NK cells, CD8+T cells, and CD4+T cells which is in the form of a non-linear differential equation. The analysis result shows that there are three tumor free equilibrium points and one coexisting equilibrium point. Some tumor free equilibrium and tumor equilibrium point exist and it is stable under certain conditions. Finally, numerical simulation is carried out to illustrate analysis result. From sensitivity analysis, it is found that the most  sensitive parameter that influence the growth rate of tumor cells are the reciprocal carrying capacity of tumor cells and the killing rate of CD8+T cells by tumor cells.
Analysis of Metabolit and Antibacterial Control of Mengkudu Leaf Extract (Morinda citrifolia) on the Bacteria of Aeromonas hydrophila Yora Utami Putri Pertiwi; Arief Prajitno; Mohamad Fadjar
Research Journal of Life Science Vol 6, No 3 (2019)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.rjls.2019.006.03.3

Abstract

A. hydrophila is an anaerobic facultative bacterium, which is a bacterium that can develop in conditions with or without oxygen. Therefore, it is necessary to use alternative materials that can be used to eliminate A. hydrophila, one of which is to use herbal medicines. The purpose of this study was to determine the content of active compounds in mengkudu leaf extract (M. citrifolia) using the disc test method. To test the content of secondary metabolites, phytochemical testing and FTIR (Fourier Transform Infrared Spectroscopy) were carried out. The results obtained are 100 ppm which is the minimum concentration that can inhibit the growth of A. hydrophila. Phytochemical test results obtained crude extract of positive mengkudu leaves alkaloids, saponins, triterpemoid and flavonoids. And in the FTIR test the most dominant content of phenol compounds contained in Mengkudu leaf extract which has a very important function that can be used as an antibacterial in this study. Further research is expected to carry out more in-depth characterization testing of active compounds through several tests including using LCMS or GCMS to determine the active ingredient of mengkudu leaves.
Morphological Characteristics of Bioactive Compounds on Api-Api Mangrove Leaves Extract (Avicennia marina) Based on Leaves Age Muhamad Zaky Zamani; Arief Prajitno; Mohamad Fadjar
Research Journal of Life Science Vol 6, No 3 (2019)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.rjls.2019.006.03.4

Abstract

Api-api leaves A. marina has a variety of active compounds that have been confirmed to too wordy be used as antibacterial agents, where harvesting of mangrove leaves is carried out at the location of Betoyoguci Gresik and differentiated by age, this age differentiation is based on morphological characteristics because it has color differences significant. Where age is one of the factors that affect the level of active compounds found in leaves. Extraction results of mangrove api-api gave different yield levels in each age level. The order of yields from the largest to the smallest is the old leaves 3%, fall 2.86% and young leaves 2.04%. Whereas based on phytochemical test the best extracts were obtained, namely old leaves, fall leaves and young leaves, FT-IR results with 10 detected absorption files which indicate the presence of functional group characteristics that can be used as an illustration of the presence of antibacterial compounds. In the LC-MS test with identification of several molecular weights which indicated a signal derivative of flavonoid compounds in the form of dihydroquercetin, quercetin-3-O-β-D-xylopyranoside, quercetin-3-O-β-D-galactopyranoside, isohametin-7-O-pentoside and routine, and derivatives of detected alkaloid compounds in the form of berberine and papaverine.

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