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Journal of Mathematical and Fundamental Sciences
ISSN : 23375760     EISSN : 23385510     DOI : https://doi.org/10.5614/j.math.fund.sci.
Core Subject : Science, Education,
Journal of Mathematical and Fundamental Sciences welcomes full research articles in the area of Mathematics and Natural Sciences from the following subject areas: Astronomy, Chemistry, Earth Sciences (Geodesy, Geology, Geophysics, Oceanography, Meteorology), Life Sciences (Agriculture, Biochemistry, Biology, Health, Medical, Pharmacy), Mathematics, Physics, and Statistics.
Articles 689 Documents
Docking Studies and Molecular Dynamics Simulation of Compounds Contained in Kaempferia Galanga L. to Lipoxygenase (LOX) for Anti-Inflammatory Drugs Supandi; Yeni; Lusi Putri Dwita
Journal of Mathematical and Fundamental Sciences Vol. 53 No. 2 (2021)
Publisher : Institute for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2021.53.2.4

Abstract

Inflammation is a self-protective response to start the healing process. An anti-inflammatory target worth developing are lipoxygenase inhibitors, which have been studied for several diseases, including severe respiratory disease. This research had the goals of estimating the activity of 21 compounds from K. galanga to inhibit the lipoxygenase (LOX) and estimating the bond stability of the ligand-LOX complex. Based on the compound’s affinity for LOX, the compounds in K. galanga were selected by utilizing the PLANTS docking software, with zileuton as the reference ligand. The GROMACS application was used to simulate the molecular dynamics of the LOX-ligand complex at 310 K. Based on the chemPLP score, most of the 21 K. galanga compounds showed a higher affinity towards 5-LOX compared to zileuton. δ-3-carene had the best affinity for 5-LOX. In the simulation of molecular dynamics until 20 ns, the RMSD of δ-3-carene and 5-LOX was not more than 0.03 nm or 0.3 Å, indicating that the whole system showed decent stability and had ‑1.67392 x 106 kcal/mol as the average potential energy. The results showed that K. galanga contains active components of 5-LOX inhibitors that could be developed.
Basin-scale Paleoecology: Using Semi-quantitative Analysis of the Ichnofabric within Kutai Basin (Indonesia) Ery Arifullah; Yahdi Zaim; Aswan; Djuhaeni
Journal of Mathematical and Fundamental Sciences Vol. 53 No. 2 (2021)
Publisher : Institute for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2021.53.2.8

Abstract

Ichnofossils are still not used in paleoecological studies, even though they are a valuable proxy for paleoecology. This study focused on a semi-quantitative approach to a number of ichnofabric variables, i.e. ichnofossil association, bioturbation index (BI), ichnodiversity (ID), number of behaviors (NB), penetration depth (PD), and burrow diameter (DM). It was proved that the scores of those variables were low to medium because of the paleoecological fluvial-marine transition depositional processes in the Serravallian-Tortonian interval in Kutai Basin, Indonesia. This paper contributes an ichnofabric model that is visualized as histograms. One histogram shows the most common ichnofossil associations found in ichnofabric units, i.e., Ophiomorpha, Skolithos, Paleophycus, Planolites, Thalassinoides, and Chondrites. The other histograms describe the ichnofabric variables scores for BI, ID, NB, PD, and DM. The variables represent low to medium scores, a characteristic of a brackish paleoecology at basin-scale, a unique indicator for the fluvial-marine transition depositional system.
Optimal Control in a Mathematical Model of Smoking Nur Ilmayasinta; Heri Purnawan
Journal of Mathematical and Fundamental Sciences Vol. 53 No. 3 (2021)
Publisher : Institute for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2021.53.3.4

Abstract

This paper presents a dynamic model of smoking with optimal control. The mathematical model is divided into 5 sub-classes, namely, non-smokers, occasional smokers, active smokers, individuals who have temporarily stopped smoking, and individuals who have stopped smoking permanently. Four optimal controls, i.e., anti-smoking education campaign, anti-smoking gum, anti-nicotine drug, and government prohibition of smoking in public spaces are considered in the model. The existence of the controls is also presented. The Pontryagin maximum principle (PMP) was used to solve the optimal control problem. The fourth-order Runge-Kutta was employed to gain the numerical solutions.
Modeling the Phenomenon of Xenophobia in Africa Reuben Iortyer Gweryina; Emilian Chinwendu Madubueze; Simon James Ogaji
Journal of Mathematical and Fundamental Sciences Vol. 53 No. 2 (2021)
Publisher : Institute for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2021.53.2.7

Abstract

In this study, we applied the principle of a competitive predator-prey system to propose a prey-predator-like model of xenophobia in Africa. The boundedness of the solution, the existence and stability of equilibrium states of the xenophobic model are discussed accordingly. As a special case, the coexistence state was found to be locally and globally stable based on the parametric conditions of effective group defense and anti-xenophobic policy implementation. The system was further analyzed by Sotomayor’s theory to show that each equilibrium point bifurcates transcritically. However, numerical proof showed period-doubling bifurcation, which makes the xenophobic situation more chaotic in Africa. Further numerical simulations support the analytical results with the view that tolerance, group defense and anti-xenophobic policies are critical parameters for the coexistence of foreigners and xenophobes.
Designing Aquifer Model for the Banks of the Serayu River, Sokawera, Somagede, Banyumas, Indonesia by Means of 1D-Electrical Resistivity Data Sehah; Hartono; Zaroh Irayani; Urip Nurwijayanto Prabowo
Journal of Mathematical and Fundamental Sciences Vol. 53 No. 3 (2021)
Publisher : Institute for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2021.53.3.1

Abstract

A geoelectric survey using the 1D-electrical resistivity method was applied to design a groundwater aquifer model for the banks of the Serayu River in Sokawera Village, Somagede District, Banyumas Regency, Indonesia. The aim of this research was to identify the characteristics of aquifers in the research area based on resistivity log data. Acquisition, modeling, and interpretation of resistivity data were carried out and the results were lithological logs at seven sounding points. Correlation between the lithological logs resulted in a hydrostratigraphic model. This model is composed of several hydrological units, i.e. shallow aquifer, aquitard, and deep aquifer. The shallow aquifers are composed of sandy clay (10.81-18.21 Wm) and clayey sand (3.04-7.43 Wm) with a depth of groundwater from the water table to 27.51 m. The deep aquifers are composed of sandstone with variation of porosity (2.24-12.04 Wm) at a depth of more than 54.98 m. Based on this model, potential shallow aquifers were estimated to be at sounding points Sch-5, Sch-6, and Sch-7. This hydrostratigraphic model shows that the two types of aquifers are separated by an aquitard layer, allowing groundwater infiltration from the shallow aquifer to the deep aquifer and vice versa. Moreover, the Serayu riverbanks in this research area are estimated to be a groundwater discharge area.
The Role of Non-pharmacological Interventions on the Dynamics of Schistosomiasis Agatha Abokwara; Chinwendu Emilian Madubueze
Journal of Mathematical and Fundamental Sciences Vol. 53 No. 2 (2021)
Publisher : Institute for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2021.53.2.6

Abstract

Schistosomiasis is a neglected tropical disease affecting communities surrounded by water bodies where fishing activities take place or people go to swim, wash and cultivate crops. It poses a great risk to the health and economic life of inhabitants of the area. This study was carried out to evaluate the impact of public health education and snail control measures on the incidence of schistosomiasis. A model was developed with attention given to the snail and human populations that are the hosts of the cercariae and miracidia respectively. The existence and stability of disease-free and endemic equilibrium states were established. The disease-free and endemic equilibrium states were shown to be locally asymptotically stable whenever the basic reproduction number was less than unity. Numerical simulations of the model were carried out to evaluate the impact of interventions (public health education and snail control measures) on schistosomiasis transmission. It was observed that the implementation of low coverage snail control with highly efficacious molluscicide and massive public health education will make the basic reproduction number smaller than unity, which implies the eradication of schistosomiasis in the population.
Inherent Irreversibility of Mixed Convection within Concentric Pipes in a Porous Medium with Thermal Radiation Oluwole Daniel Makinde; Adetayo Samuel Eegunjobi
Journal of Mathematical and Fundamental Sciences Vol. 53 No. 3 (2021)
Publisher : Institute for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2021.53.3.5

Abstract

This work investigated the thermal putrefaction and inherent irreversibility in a steady flow of an incompressible inconstant viscosity radiating fluid within two concentric pipes filled with a porous medium. Following the Brinkmann-Darcy-Forchheimer approach, the nonlinear differential equations governing the model were obtained. The model boundary value problem was addressed numerically via a shooting quadrature with the Runge-Kutta-Fehlberg integration scheme. The effects of diverse emerging parameters on the fluid velocity, temperature, skin friction, Nusselt number, entropy generation rate and the Bejan number are provided in graphs and discussed in this paper.
Slater-Pauling-like Behavior of Spin Hall Conductivity in Pt-based Superlattices Abdul-Muizz Pradipto; Kohji Nakamura
Journal of Mathematical and Fundamental Sciences Vol. 53 No. 3 (2021)
Publisher : Institute for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2021.53.3.3

Abstract

The intrinsic spin Hall effect in the bulk systems of late  transition metals (Os, Ir, Pt, and Au) as well as the Pt-based superlattices were investigated by using first-principle calculations. By comparing the computed spin Hall conductivities of Pt−M superlattices (M=Os, Ir, and Au) with different compositions and those obtained from atomic bulk composition, we saw that the spin Hall conductivities (SHCs) follow the behavior described by the Slater-Pauling curve, the maximum of which is at pure Pt bulk. From the examination of the band structures of the considered systems, we found that the origin of this behavior comes from the variation of the band structures as a direct consequence of the change of the number of electrons and hybridization effects.
Delay Time Parameter and Its Confidence Interval of Predictive Time Series of COVID-19 Outbreak Between the First and the Second Wave Rapin Sunthornwat; Sirikanlaya Sookkhee
Journal of Mathematical and Fundamental Sciences Vol. 53 No. 2 (2021)
Publisher : Institute for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2021.53.2.9

Abstract

The outbreak of coronavirus disease 2019 (COVID-19) has become a major problem facing humans all around the world. For governments, in order to deal with the outbreak and protect the population, it is important to predict the number of infectious cases in the future to monitor the COVID-19 situation. This research aimed to compare the effectiveness of the logistic and the delay logistic time series in predicting the total number of infectious cases by using actual data from four countries, i.e. Thailand, South Korea, Egypt, and Nigeria. The total number of COVID-19 cases was collected during the first and the second wave of the COVID-19 outbreak. The validation and accuracy of the predictive growth curve time series were determined based on statistical values, i.e. the coefficient of determination and the root mean squared percentage error. It was found that the logistic time series was more appropriate for predicting the first wave in the four countries. For the second wave, the delay logistic time series was preferable. Moreover, the confidence interval based on Chebyshev’s inequality of delay time between the first and the second wave of the COVID-19 outbreak is also proposed.
Cover Vol. 53, No. 2, 2021 Journal of Mathematical and Fundamental Sciences
Journal of Mathematical and Fundamental Sciences Vol. 53 No. 2 (2021)
Publisher : Institute for Research and Community Services (LPPM) ITB

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