cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Muchtaridi
Contact Email
ijpsteditor@gmail.com
Phone
-
Journal Mail Official
ijpsteditor@gmail.com
Editorial Address
-
Location
Kota bandung,
Jawa barat
INDONESIA
Indonesian Journal of Pharmaceutical Science and Technology
Published by Universitas Padjadjaran
ISSN : 23561971     EISSN : 2406856X     DOI : -
Core Subject : Health, Science,
Computer Science & IT Medicine & Pharmacology
Jurnal Sains dan Teknologi Farmasi Indonesia (IJPST) adalah publikasi ilmiah pada seluruh aspek Sains dan Teknologi Farmasi. Jurnal ini diterbitkan 3 kali setahun untuk menyediakan forum bagi apoteker, dan profesional kesehatan lainnya untuk berbagi praktik terbaik, meningkatkan jaringan kerja dan pendekatan yang lebih kolaboratif dalam Sains dan Teknologi Farmasi.
Arjuna Subject : -
Articles 7 Documents
 1 
Search results for , issue "Vol 10, No 1 (2023)" : 7 Documents clear
Antibacterial Activity of Rosemary Oil Against Propionibacterium acnes and The Formulation into Nanoemulsion System Sani Ega Priani; Rizza F. Nurasyfa; G.C. Eka Darma; Sri P. Fitraningsih; Livia Syafnir; Robby Prayitno
Indonesian Journal of Pharmaceutical Science and Technology Vol 10, No 1 (2023)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v10i1.35770

Abstract

Acne is an inflammatory condition of the pilosebaceous unit that can occur due to infection ofPropionibacterium acnes. Rosemary essential oil contains various active compounds that haveantibacterial activity. Nanoemulsions have been developed as a delivery system to the pilosebaceousunit. This study aimed to determine the antibacterial activity of rosemary oil against P. acnes anddevelop it into a nanoemulsion system. The antibacterial activity was conducted by the agar diffusionmethod. Rosemary oil contains 1,8-cineole as the main active compound and has antibacterial activityagainst P. acnes with an inhibitory zone of 11.315±0.069 mm at a concentration of 4%. Rosemaryoil was successfully developed into a nanoemulsion system using Tween 80 as a surfactant and acombination of ethanol and PEG 400 as a co-surfactant. The rosemary nanoemulsion has a clearphysical appearance with an average globule size of 33.50±0.01 nm and a PDI value of 0.45±0.03. Thepreparation has good physical stability based on centrifugation, heating cooling, and freeze-thaw tests.The study shows that rosemary oil has antibacterial activity against P. acnes and has been successfullydeveloped into nanoemulsion preparations with good characteristics and physical stability. Keywords: Acne vulgaris, Nanoemulsion, Propionibacterium acnes, Rosemary oil.
19 Molecular Docking Analysis of Volatile Compounds from Fraction of Eichhornia crassipes Herbs Ethanol Extract As α-Glucosidase Inhibitor Diniatik Diniatik; Eka Retnowati; Asmiyenti D. Djalil
Indonesian Journal of Pharmaceutical Science and Technology Vol 10, No 1 (2023)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v10i1.32399

Abstract

Phenolics and Flavonoids Content of Wijaya Kusuma Leaves Fractions using Micro-plate Based Assay Ni Putu Ermi Hikmawanti; Agustin Yumita; Muhammad Rafiq; Lusiana Lusiana
Indonesian Journal of Pharmaceutical Science and Technology Vol 10, No 1 (2023)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v10i1.35828

Abstract

Epiphyllum oxypetalum (DC.) or Wijaya Kusuma (Cactaceae) is an ornamental plant which is knownto contain polyphenol compounds. The purpose to determine the levels of total phenolic and flavonoidcompounds in the fractions of Wijaya Kusuma leaves using microplate-based assay. Each sample wasdetermined phenolic content with Folin-ciocalteu reagent and flavonoid content using AlCl3 on themicroplate. Absorption was measured using a microplate reader. Screening of DPPH radical scavengingactivity was identified using the TLC method. The results showed that the extract and fractions ofthe leaves of Wijaya Kusuma contained phenolic and flavonoid compounds. The ether fraction hadthe highest phenolic content (35,912±0,54776 mgGAE/g) and flavonoids (0,773±0,008 mgQE/g)compared to other fractions (ether>water>ethyl acetate fraction). There is one yellow spot with an Rfvalue of 0,85 in the ether fraction which is thought to be a compound capable of scavenging the DPPHradicals. The ether fraction of Wijaya Kusuma leaves has potential as a source of polyphenols withantioxidant activity. However, further research is needed to evaluate the antioxidant capacity in theether fraction of Wijaya Kusuma leaves.Keywords: Antioxidant, Epiphyllum oxypetalum (DC.) Haw, Flavonoids, Fraction, High-throughputMicroplate Assay, Phenolics.
Analysis of Waste Minimization in Production Time to Increase Production Effectiveness Nalia El-Huda Ismail; Andri Nugraha Nugraha Sutomo; Muchtaridi Muchtaridi
Indonesian Journal of Pharmaceutical Science and Technology Vol 10, No 1 (2023)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v10i1.34905

Abstract

Lean manufacturing has been widely applied in the industry as an effort to utilize resources efficientlyand systematically. The purpose of this study is to analyze waste time activities and to proposedminimize the time so it will increase the effectiveness of production sucralfate suspension at PT. X.The concept used in this research is lean manufacturing with a value stream mapping (VSM) approach.This method will make it easier to identify waste time activities through current state mapping, todetermine improvement points and to propose improvements by describing the value stream mapping.The research was carried out by calculating and mapping each step of the production of sucralfatesuspension. The total production time needed for the production of one batch of sucralfate suspensionis 5 hours 16 minutes with a value added activity time about 96%, and a necessary non value addedactivity time about 4%. The proposed improvement to minimize waste time is by carrying outproductions activities in parallel. Based on the proposed improvement, the total production time ofsucralfate syrup that can be reduced is 31 minutes.Keywords: Waste Time, Value Stream Mapping.
Potency of Honje Hutan Flowers (Etlingera Hemisphaerica (Blume) R.M.Sm.) as Alpha-Glucosidase Inhibitor Soraya Riyanti; Nandi Agustian; Akhirul Kahfi Syam
Indonesian Journal of Pharmaceutical Science and Technology Vol 10, No 1 (2023)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v10i1.35453

Abstract

The Pangandaran people process honje flowers into fresh drinks that are consumed for health. Theforest honje leaf extract provides antidiabetic activity at a dose of 0.39 mg/g BW can reduce bloodglucose levels by 36.16% has been reported. Limited scientific information from honje hutan flowers,it is necessary on its activity as an alpha-glucosidase inhibitor and study its chemical content. Theextraction process was macerated in 70% ethanol for 24 hours and the fractionation process wascarried out by liquid-liquid extraction method with n-hexane, ethyl acetate and water as solvents.Testing the activity of alpha-glucosidase inhibitors colorimetrically using the chromogenic substratep-nitrophenyl α-D-glucopyranoside, alpha-glucosidase enzymes derived from Saccharomycescerevisiae, measurement of absorption at a maximum wavelength of 401.3 nm and acarbose usedas a comparison drug alpha-glucosidase inhibitors. The results showed that the forest honje flowerscontain flavonoids, polyphenols, tannins, quinones, monoterpenoids, and sesquiterpenoids. IC50 valuesfor 70% ethanol extract, n-hexane, ethyl acetate, water and acarbose fractions were 136.79, 307.18,277.12, 66.18, and 14.63 g/mL respectively. The water fraction gave the best inhibitory activity againstalpha-glucosidase with an IC50 value of 66.18 g/mL.Keywords: Etlingera hemisphaerica (Blume) R.M.Sm, honje hutan flowers, alpha-glucosidaseinhibitor.
Subcronic Toxicity Of Moringa Leaf Extract (Moringa Oleivera L) On Histopathology Heart Organ Of Rats yunda putri listiani; Novi - Ayuwardani; susanti - erikania
Indonesian Journal of Pharmaceutical Science and Technology Vol 10, No 1 (2023)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v10i1.35662

Abstract

Moringa leaf (Moringa oleivera L) is a plant that has benefits as a natural medicinal ingredient. Benefits of Moringa leaves as anti-inflammatory, antimicrobial, antioxidant, antihypertensive, anticholesterol and antidiabetic. Phytochemical test Moringa leaves contain flavonoids, alkaloids, saponins, tannins, phenols and steroids. Sub-chronic toxicity test was conducted to determine the negative impact of Moringa leaves on the body if consumed for a certain period of time. The test animals used were 20 male rats with 5 doses of treatment. Parameters observed were body weight (g), relative weight of liver (%), macroscopic changes and liver histopathology. The data were analyzed by One Way Anova and continued with the Post Hoc LSD test. The results of this study showed changes in body weight of rats, changes in the relative weight of the liver, macroscopic changes in the liver in the form of consistency and surface of the liver and histopathological changes in the liver in the form of necrosis with a total liver damage of 46% and the number of normal cells by 54%. Keywords: Moringa Leaf, Subchronic Toxicity, Liver Histopathology.
Antimalarial Activity of Ethanol Extract of Sampare Leaves (Glochidion sp var. Biak) Against Plasmodium falciparum In Vitro khairuddin zainuddin umar; Yuri P.Utami; Muhammad A.Y. Ardi
Indonesian Journal of Pharmaceutical Science and Technology Vol 10, No 1 (2023)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v10i1.29477

Abstract

Malaria is one of the health problems in the world and in Indonesia. This disease is caused by theprotozoan parasite, the genus Plasmodium. Plasmodium falciparum is the most important parasiticdisease with high morbidity and mortality in the world and tropical countries such as Indonesia inparticular. This study aims to determine the activity of sampare leaf extract in inhibiting the growth ofthe FCR-3 strain of the P. falciparum parasite which causes malaria. Sampare leaves were extracted bymaceration method using 70% ethanol. Extract the results extraction were tested against P. falciparumby in vitro method. 32,67% Yield extract resulted from the extraction process. Phytochemical screeningshows the presence of alkaloid compounds, flavonoids, quinones, saponins, and tannins. The ethanolextract of sampare leaves had IC50 antimalarial activity of 0,125 μg/mL and was categorized very well.Keywords: Antimalarial, Glochidion sp var. Biak, IC50, Plasmodium falciparum.

Page 1 of 1 | Total Record : 7

 1 

Filter by Year

2023 2023


Reset
Filter By Issues
All Issue Vol 12 (2025): Vol. 12 Suppl. 2 (2025) 2025: Vol. 12 Suppl. 1 (2025) Vol 12, No 3 (2025) Vol 12, No 2 (2025) Vol 12, No 1 (2025) 2024: Suppl. 6, no. 3 (The 3rd Mandala Waluya International Conference on Pharmaceutical Science and Vol 11, No 3 (2024) Vol 11, No 2 (2024) Vol 11, No 1 (2024) 2024: Suppl. 6, No. 2 (Universitas Halu Uleo Conference) 2024: Suppl. 6, No. 1 (Special Issue for Mulawarman Pharmaceutical Conference) Suppl. 5, No. 2 (2023) Special Issue for The 3rd Bandung International Teleconference on Pharmacy (B Vol 10, No 3 (2023) Vol 10, No 2 (2023) Vol 10, No 1 (2023) Suppl. 5, No. 1 (2023) Vol 9, No. 3, 2022 Vol 9, No. 2, 2022 Vol 9, No 1 (2022) Suppl. 4, No. 1 (2022) Vol 8, No 3 (2021) Vol 8, No 2 (2021) Vol 8, No 1 (2021) Suppl. 3, No. 1 (2021) Vol 7, No 3 (2020) Vol 7, No 2 (2020) Vol 7, No 1 (2020) Vol 6, No 3 (2019) Vol 6, No 2 (2019) Vol 6, No 1 (2019) Vol 6, No 1 (2019 In Press) Suppl. 2, No. 3 (2019) Suppl. 2, No. 2 (2019) Suppl. 2, No. 1 (2019) Vol 5, No 3 (2018) Vol 5, No 3 (2018) Vol 5, No 2 (2018) Vol 5, No 2 (2018) Vol 5, No 1 (2018) Vol 5, No 1 (2018) Suppl 1, No. 1 (2018) Suppl 1, No. 1 (2018) Vol 4, No 3 (2017) Vol 4, No 3 (2017) Vol 4, No 2 (2017) Vol 4, No 2 (2017) Vol 4, No 1 (2017) Vol 4, No 1 (2017) Supp 1, No 1 (2017) Supp 1, No 1 (2017) Vol 3, No 3 (2016) Vol 3, No 3 (2016) Vol 3, No 2 (2016) Vol 3, No 2 (2016) Vol 3, No 1 (2016) Vol 3, No 1 (2016) Vol 2, No 3 (2015) Vol 2, No 3 (2015) Vol 2, No 2 (2015) Vol 2, No 2 (2015) Vol 2, No 1 (2015) Vol 2, No 1 (2015) Vol 1, No 2 (2014) Vol 1, No 2 (2014) Vol 1, No 1 (2014) Vol 1, No 1 (2014) More Issue