Indonesian Journal of Tropical and Infectious Disease
This journal is a peer-reviewed journal established to promote the recognition of emerging and reemerging diseases specifically in Indonesia, South East Asia, other tropical countries and around the world, and to improve the understanding of factors involved in disease emergence, prevention, and elimination.
The journal is intended for scientists, clinicians, and professionals in infectious diseases and related sciences. We welcome contributions from infectious disease specialists in academia, industry, clinical practice, public health, and pharmacy, as well as from specialists in economics, social sciences and other disciplines.
Articles
11 Documents
Search results for
, issue
"Vol. 2 No. 1 (2011)"
:
11 Documents
clear
<![CDATA[HEPATITIS VIRUS INFECTION IN REPEATEDLY TRANSFUSED THALASSEMIA PATIENTS ]]>
<![CDATA[Andarsini, Mia Ratwita]]>
<![CDATA[ Indonesian Journal of Tropical and Infectious Disease Vol. 2 No. 1 (2011) ]]>
Publisher : <![CDATA[Institute of Topical Disease Universitas Airlangga ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (226.225 KB)
|
DOI: 10.20473/ijtid.v2i1.190
<![CDATA[Patients of thalassemia who are conventionally treated by a regular transfusion regimen, are at a risk of developing transfusion transmitted infections, including hepatitis. The present study was conducted to evaluate the prevalence of hepatitis virus infection in repeated transfused thalassemia patients. A total of 83 patients of thalassemia who had received at least 10 transfusions were tested for HBs Ag, anti HBs and anti-HCV using ELISA. Amongst these patients, HBs Ag, anti HBs and anti HBC were detected in 1.2%, 26.5% and 12% patients respectively. the prevalence of HBV and HCV infection were in agreement with the findings in other study.]]>
<![CDATA[EXPRESSION OF b-XYLOSIDASE ENCODING GENE IN PHIS/ Bacillus megaterium MS SYSTEM ]]>
<![CDATA[Sumarsih, Sri]]>
<![CDATA[ Indonesian Journal of Tropical and Infectious Disease Vol. 2 No. 1 (2011) ]]>
Publisher : <![CDATA[Institute of Topical Disease Universitas Airlangga ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (1405.694 KB)
|
DOI: 10.20473/ijtid.v2i1.185
<![CDATA[b-Xylosidase encoding gene from G. thermoleovorans IT-08 had been expressed in the pHIS1525/ B. megaterium MS941 system. The b-xylosidase gene (xyl) was inserted into plasmid pHIS1525 and propagated in E. coli DH10b. The recombinant plasmid was transformed into B. megaterium MS941 by protoplast transformation. Transformants were selected by growing the recombinant cells on solid LB medium containing tetracycline (10 µg/ ml). The expression of the b-xylosidase gene was assayed by overlaid the recombinant B. megaterium MS941 cell with agar medium containing 0.2% ethylumbelliferyl-b-D-xyloside (MUX). This research showed that the b-xylosidase gene was succesfully sub-cloned in pHIS1525 system and expressed by the recombinant B. megaterium MS941. Theaddition of 0.5% xylose into the culture medium could increase the activity of recombinantactivity of recombinant of recombinantb-xylosidase by 2.74 fold. The recombinant B. megaterium MS941 secreted 75.56% of the expressed b-xylosidase into culture medium. The crude extract b-xylosidase showed the optimum activity at 50° C and pH 6. The recombinant b-xylosidase was purified from culture supernatant by affinity chromatographic method using agarose containing Ni-NTA (Nickel-Nitrilotriacetic acid). The pure b-xylosidase showed a specific activity of 10.06 Unit/mg protein and relative molecular weight ± 58 kDa.]]>
<![CDATA[BASIC MECHANISM OF HYPERBARIC OXYGEN IN INFECTIOUS DISEASE ]]>
<![CDATA[Widiyanti, Prihartini]]>
<![CDATA[ Indonesian Journal of Tropical and Infectious Disease Vol. 2 No. 1 (2011) ]]>
Publisher : <![CDATA[Institute of Topical Disease Universitas Airlangga ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (378.726 KB)
|
DOI: 10.20473/ijtid.v2i1.191
<![CDATA[Hyperbaric oxygen therapy (HBOT) is the inhalation of 100 percent oxygen inside a hyperbaric chamber that is pressurized to greater than 1 atmosphere (atm). HBOT causes both mechanical and physiologic effects by inducing a state of increased pressure and hyperoxia. HBOT is typically administered at 1 to 3 atm. While the duration of an HBOT session is typically 90 to 120 minutes, the duration, frequency, and cumulative number of sessions have not been standardized. HBO has been use widely in treating gangrene diabetic, stroke, osteomyelitis and accelerating wound healing. The use of HBO in infectious disease is wide, so the mechanism of hyperbaric oxygen in infectious disease should be well-understand. This understanding could bring the proper and wise management of infectious disease and to prevent the side effect of each therapy.]]>
<![CDATA[THE ROLE OF POLYSACCHARIDE KRESTIN FROM Coriolus versicolor MUSHROOM ON IMMUNOGLOBULIN ISOTYPE OF MICE WHICH INFECTED BY Mycobacterium tuberculosis ]]>
<![CDATA[Permanasari, Adita Ayu]]>
<![CDATA[ Indonesian Journal of Tropical and Infectious Disease Vol. 2 No. 1 (2011) ]]>
Publisher : <![CDATA[Institute of Topical Disease Universitas Airlangga ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (532.663 KB)
|
DOI: 10.20473/ijtid.v2i1.186
<![CDATA[This research was aimed to determine the role of polysaccharide krestin (PSK) with different timing on levels and types of mice immunoglobulin (Ig) isotype which infected by Mycobacterium tuberculosis. This research used 30 adult female mice of Mus musculus strain, polysaccharide krestin was isolated from Coriolus versicolor mushroom, and for infection used Mycobacterium tuberculosis H37Rv (ATCC 27294 T) strain. Provision of polysaccharide krestin was done over 7 consecutive days via gavage. Mycobacterium tuberculosis infection was done 2 times with an interval of 1 week via intraperitoneal. Immunoglobulin isotype serums were analyzed using the ELISA test and the results were analyzed descriptively through the color reaction and OD values. The result showed the highest levels of immunoglobulin was found in the provision of PSK before and after Mycobacterium tuberculosis infection with total 6.280 of OD Ig isotype. Immunoglobulin isotype dominant was IgM with lambda light chain. The conclusion of this research was PSK increased mice Ig isotype levels at the time of provision before, after or before and after infection Mycobacterium tuberculosis. Ig isotype which was formed i.e. IgM, IgA, IgG2b, IgG3, IgG2a, IgG1 with kappa and lambda light chain.]]>
<![CDATA[UPDATE MANAGEMENT OF DENGUE COMPLICATION IN PEDIATRIC ]]>
<![CDATA[Soegijanto, Soegeng]]>
<![CDATA[ Indonesian Journal of Tropical and Infectious Disease Vol. 2 No. 1 (2011) ]]>
Publisher : <![CDATA[Institute of Topical Disease Universitas Airlangga ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (2504.235 KB)
|
DOI: 10.20473/ijtid.v2i1.91
<![CDATA[Dengue virus infection is one of the important health problems in Indonesia, although the mortality rate has been decreased but many dengue shock syndrome cases is very difficult to be solving handled. It might be due to nature course of dengue virus infection is very difficult to predict of the earlier time of severity occur. THE AIM To get idea to make update management of dengue complication in pediatric. MATERIAL AND METHOD Data were compiled from Dr. Soetomo Hospital Surabaya in 2009. The diagnosis of all cases was based on criteria WHO 1997 and PCR examination in Institute Tropical Disease for identified serotype of dengue virus infection. The unusual cases of dengue virus infection were treated following the new WHO protocol in 2009. RESULT There were only 3 cases with serotype DEN 1, consisted 2 cases had age 1–4 years and 1 had age 5–14 years. 2 cases showed a severe clinical performance as dengue shock syndrome and 1 case showed as unusual case of dengue virus infection. Three report cases of: a. Dengue hemorrhagic fever grade III which liver involvement and had bilateral pleural effusion; b. Dengue hemorrhagic grade III with liver involvement and encephalopathy; c. Dengue hemorrhagic grade III with liver involvement acute kidney injury, myocardial involvement and encephalopathy. All the patients were treated according to new edition WHO protocol and all of the involving organ recovered along with the improvement of the disease. CONCLUSION Update management of dengue complication pediatric should be learned carefully used for helping unusual cases of dengue virus infection.]]>
<![CDATA[RI SK FACTOR OF BACTEREMI A I N CHI LDREN WI TH PNEUMONIA ]]>
<![CDATA[Asih, Retno]]>
<![CDATA[ Indonesian Journal of Tropical and Infectious Disease Vol. 2 No. 1 (2011) ]]>
Publisher : <![CDATA[Institute of Topical Disease Universitas Airlangga ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (361.223 KB)
|
DOI: 10.20473/ijtid.v2i1.187
<![CDATA[Background: Pneumonia is known as a frequent cause of morbidity and mortality among children in developing countries. In children,it caused predominantly by bacteria. Bacteremia has been associated with severity and mortalitas of pneumonia. Identify factors caused bacteremia important to prevent severity and mortalitas of pneumonia. Objective: The objective of this study was to identify risk factors of bacteremia in children with pneumonia. Methods: A retrospective study was conducted in children with pneumonia in Dr. Soetomo Surabaya Hospital from January 2007 to December 2008. Blood cultures be performed on all of this patients. Factors associated with bacteremia were identified following review of medical records include clinical features, laboratory , radiology and blood culture results. Results: Frequency of bacteremia was 8,2% (36 patients) of 438 children with pneumonia. Interval from onset of symptoms to hospital admission more than 5 days (22.69 CI 95%), severe malnourished (OR 9.05 CI 95%), anemia (OR 2.44 CI 95%), leucocyt counts less than 5000/mm3 and more than 20.000/mm3 (OR 2.41 CI 95%) and paO2 less than 80 mmHg (OR 4.25 CI 95%) were at increased risk of bacteremia in children with pneumonia. Conclusion: Risk factors bacteremia in children with pneumonia included age under 1 year, symptoms more than 5 days, severe malnourished ,anemia, leucosyt counts less than 5000/mmand more than 20.000/mm3 and paO2 less than 80 mmHg.]]>
<![CDATA[PROFILE OF COMMUNITY ACQUIRED PNEUMONIA IN CHILDREN AT SOETOMO HOSPITAL SURABAYA IN 00–00 ]]>
<![CDATA[Setyoningrum, Retno Asih]]>
<![CDATA[ Indonesian Journal of Tropical and Infectious Disease Vol. 2 No. 1 (2011) ]]>
Publisher : <![CDATA[Institute of Topical Disease Universitas Airlangga ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (240.945 KB)
|
DOI: 10.20473/ijtid.v2i1.92
<![CDATA[Background: Community Acquired Pneumonia (CAP) is one of the most important health problem affecting children all over the world. Clinical findings, laboratory and radiological examination of CAP may largely vary from mild to severe. Objective: To report profile of CAP in children hospitalized at Soetomo Hospital Surabaya in 2007–2008 Methods: This research was a retrospective study. Data of children with primary diagnosis of CAP in 2007–2008 were obtained from medical records of the Department of Child Health Soetomo Hospital Surabaya. The diagnosis CAP was based on WHO criteria (pneumonia clinical syndrome). The clinical features of illness, laboratory and radiological examination were recorded and presented descriptively. Results: During the study period, 438 patients were diagnosed as CAP. More than half (83.4%) patients aged 3 months– 3 year. Beside cough and tachypnea, most common symptom and signs were chest indrawing (76.2%) and fever (23.8%). Leucocytosis (39.6%). Bacteria was found in 8.2%. Accompanying diseases (i.e congenital heart disease, neurological and gastroenterological disorders) were found in 36.4%. One hundred fifty seven patients (35.8%) had malnutrition. Patchy infiltrate was found in 80.8% chest X-ray examination. Mortality was found in 4.3%. Conclusions: Community acquired pneumonia in children still count as a major problem at Soetomo Hospital Surabaya.]]>
<![CDATA[EFFECT OF CYNAMMYLDEHYDE FROM CINNAMON EXTRACT AS A NATURAL PRESERVATIVE ALTERNATIVE TO THE GROWTH OF Staphylococcus aureus BACTERIA ]]>
<![CDATA[Winias, Saka]]>
<![CDATA[ Indonesian Journal of Tropical and Infectious Disease Vol. 2 No. 1 (2011) ]]>
Publisher : <![CDATA[Institute of Topical Disease Universitas Airlangga ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (631.678 KB)
|
DOI: 10.20473/ijtid.v2i1.188
<![CDATA[Food is one of the best media for the microorganism to live and grow. Therefore, food is often broken because it has been contaminated by the microorganism. In industry country, approximately 30% of population infected by food borne disease. Food borne disease is caused of phatogen bacteria food borne. Staphylococus aureus is a kind of bacteria that can make food rotten and also it is a phatogen bacteria cause food born disease, no forming spora, positive gram bacteria and the food substance which is contaminated by Staphylococus aureus will cause poisoned becaused of enterotoxin which is heat resisting. Essential oil is antimicrobial and anti bacterial that the most effective, it can inhibit the growing of microba and bacteria. One of the example of essential oil is Cinnamon.sp oil. Cinnamon oil is antimcroba agent for bacteri and fungi because it contain cynammyldehyde and cynammyl alcohol and also eugenol. The aim of this study is to understand the antimcrobacterial potential of cynammyldehyde from cinnamon extract to Staphylococus aureus. This study is laboratory experimantal research. Essential oil from Cinnamon by destilation, then redistilation was done to get cynammyldehyde from cinnamon. Cynammyldehyde was tested to Staphylococus aureus. Test method was done as dilution in the form. From this result, it show that cynammyldehide from cinnamon extract has ability in inhibit the Staphylococus aureus growth. We can conclude that Cynammaldehyde from cinnamon extract has antibacterial effect especially for positive gram bacteria that is Staphylococcus aureus. The optimum inhibiting effort is 0.09%.]]>
<![CDATA[ASSOCIATION BETWEEN ATYPICAL DEPOLARIZATION IN CELLDYN 00 AND THE PRESENCE OF PLASMODIUM SPP IN BLOOD IN Dr. SOETOMO HOSPITAL SURABAYA ]]>
<![CDATA[Nugraha, Jusak]]>
<![CDATA[ Indonesian Journal of Tropical and Infectious Disease Vol. 2 No. 1 (2011) ]]>
Publisher : <![CDATA[Institute of Topical Disease Universitas Airlangga ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (1434.143 KB)
|
DOI: 10.20473/ijtid.v2i1.94
<![CDATA[Background: Malaria is a parasitic disease worldwide with a high morbidity and mortality. A rapid and accurate method is needed to detect the presence of malaria parasites in blood. A flagging system atypical depolarization (atypdep) in CBC results from Cell-Dyn 3200 has been related with malaria infection. Materials and Methods: An observational cross sectional approach with 48 samples obtained from inpatients of the Dr.Soetomo Hospital, Surabaya. Samples were screened by Cell-Dyn 3200 analyzer for atypdep flagging in CBC. Positive samples were later confirmed by microscope to detect malaria parasites. results: From 48 samples with atypdep flagging, 7 samples were malaria positive on peripheral blood smear (13.1%). Most frequent atypdep flagging was seen in malignancy (18.7%), and approximately 54.6% of the samples were not accompanied by fever symptoms. Lekositosis and anemia each were found in 20 samples (41.6%) and thrombocytopenia in 33.3%. conclusion: The presence of atypdep flagging in Cell-Dyn 3200 does not necessarily indicate the existence of malaria or it could be said that atypdep flagging is not always associated with presence of malaria infection. The usage of an atypdep flagging in non-endemic areas such as Surabaya is just an alert sign to evaluate malaria infection rather than a screening method to detect malaria.]]>
<![CDATA[BIOCOMPATIBILITY OF AZITROMICYN ON CONNECTIVE TISSUE ]]>
<![CDATA[Kurnia, Shafira]]>
<![CDATA[ Indonesian Journal of Tropical and Infectious Disease Vol. 2 No. 1 (2011) ]]>
Publisher : <![CDATA[Institute of Topical Disease Universitas Airlangga ]]>
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (592.551 KB)
|
DOI: 10.20473/ijtid.v2i1.189
<![CDATA[Background: periodontal disease is commonly caused by bacteria, especially actinomyces actinomycetemcomitans and porphyromonas gingivalis have an abilty enter epithelial cells objectives: to investigate systemic azithromycin as the antibiotic of choice for periodontal disease based on biocomptability test in connective tissue. Material and Methods: BHK 21 cell lines were exposed to 0.025%, 0.050%, 0.075%, and 0.1% azithromycin solution for seven times. Samples were put in incubator for 24 hours. Result: Azitrromycin 0.050%-0.1% showed significant difference between life cells percentage and control, however, azithromycin 0.025% revealed insignificant difference with control. Conclusion: 0.025% azithromycin was considered biocompatible with connective tissue and 0.050% was not.]]>
