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INDONESIA
STOMATOGNATIC- Jurnal Kedokteran Gigi
Published by Universitas Jember
ISSN : 16936485     EISSN : 24424935     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Terbit dua kali setahun pada bulan Maret dan Oktober. Berisi tulisan yang berupa hasil penelitian, hasil pemikiran (review article), laporan kasus (case report) dan obituary bidang Ilmu Kedokteran Gigi.
Arjuna Subject : -
Articles 8 Documents
 1 
Search results for , issue "Vol 16 No 2 (2019)" : 8 Documents clear
Pengaruh Bisphenol-A (BPA) terhadap Kadar Insulin Pada Hepar Tikus Wistar Jantan Rizky Purboningtyas; Zahreni Hamzah; Swasthi Prasetyarini
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 16 No 2 (2019)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/stoma.v16i2.23089

Abstract

Bisphenol-A (BPA) is a synthetic chemical substance in the form of monomers which is commonly used as plastic constituents. BPA is often found in household appliances, food and beverage containers, and in dental sealants and acrylic base dentures. BPA can contaminate or enter the human body mostly through oral route or swallowed along with food consumed. It is known that BPA exposure through the oral route can cause several diseases, and one of them is endocrine and metabolic problems, which is Diabetes Mellitus. This study was to analyze the decrease of insulin levels in the liver of male Wistar rats after being exposed by BPA. 18 adult male Wistar rats were divided into 3 groups. Group I (control 1) was not given any treatment, only acclimatized for 7 days. Group II (control 2) was treated with sterile aquadest orally for 28 days. Group III (treatment group) was given oral BPA treatment with a dose of 20 mg / kg body weight for 28 days. After sacrificed, the hepar was homogenated and the insulin level was determined by ELISA. Data were analyzed with One Way Anova test and LSD test. Bisphenol-A (BPA) with a dose of 20 mg/kgBB exposed for 28 days can reduce on hepar insulin levels in adult male Wistar rats.
Aktivitas Antioksidan dan Total Polisakarida Ekstrak Rumput Laut Merah, Hijau dan Coklat dari Pantai Jangkar Situbondo Didin Erma Indahyani; Depi Praharani; Izzata Barid; Ari Tri Wanodyo Handayani
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 16 No 2 (2019)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/stoma.v16i2.23094

Abstract

The antioxidant activity and polysaccharide composition of seaweed is influenced by species (red, green and brown seaweed), geographical conditions, extraction methods, solvents, temperature and the length of time of extraction. The purpose of this study was to known the total polysaccharide and antioxidant activity in red, green and brown seaweed extracts from Jangkar Situbondo beach. Method. The study was conducted on red, green and brown seaweed extracted with ethanol and water to determine total polysaccharides. Antioxidant analysis uses the method 2,2-diphenyl1-picrylhydrazyl (DPPH) radical. Total polysaccharide and antioxidant activity were observed statistically using two-way ANOVA. The results of this study show that the polysaccharide content in seaweed water extract was significantly higher than ethanol extract, especially in brown seaweed. Seaweed water extracts showed higher antioxidant activity than ethanol extracts. The antioxidant activity of brown seaweed was significantly higher than that of green and red seaweed. Conclusion. Seaweeds have high antioxidant activity in water extracts. Brown seaweed water extract contains high polysaccharides than green and red seaweed. Antioxidant activity in brown seaweed is also higher than in green and red seaweed.
Senyawa Daun Rasamala (Altingia excelsa Nornha) sebagai Penghambat Proliferasi Sel Kanker Lidah Manusia In Vitro Risyandi Anwar; Arlette Setiawan; Supriatno Supriatno; Unang Supratman
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 16 No 2 (2019)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/stoma.v16i2.23090

Abstract

Tongue cancer is a common malignant in the oral cavity and to now medically succes its no good so often treated of life. The aims of study were to identify the secondary matabolities of Rasamala leaves, to examine the compound of Rasamala leaves toward SP-C1 cell growth inhibition. True experimental laboratories design using SP- C1 oral tongue cancer cell line was used. The ethyl acetate extract was separated their secondary metabolites by various chromatographic techniques guided by antiproliferasi activity to yield five compounds, as 3,4-dihydroxy benzoic acid (1), gallic acid (2), and apigenin (3). Compounds 1-3 were tested on their antiproliferative activity against cancer cells tongue SP-C1 and showed IC 50 values of  100,  100, and  100 μg/mL, respectively. Data analysis using ANACOVA assay, Tukey HSD with the level of significance α=0.05. In conclusion, compound from Rasamala leaves have a strong anticancer activity in human oral tongue cancer SP-C1 through inhibit cell prolieration..
Cover STOMATOGNATIC Volume 16 No 2 (2019) Jurnal STOMATOGNATIC
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 16 No 2 (2019)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Perbedaan Perubahan Warna Permukaan Resin Komposit Nanohybrid Pasca Perendaman dalam Cuko Pempek (Saus Manis dan Asam) dan Jamu Kunyit Asam (Curcuma Domestica Val – Tamarindus Indica) Budiono Budiono; Nabila Farah Khoirunnisa; Seffy Vera Faylina
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 16 No 2 (2019)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/stoma.v16i2.23091

Abstract

The advantages of Nanohybrid composite resin are they have a smooth surface and greater strength, also minimal shrinkage. The disadvantages of composite resin are the color changes extrinsically and intrinsically. The color is changing extrinsically because of the dyes which attached to the surface of the composite resin and the color is changing intrinsically due to oxidation of monomers. Pempek and turmeric-tamarind herbal drink (jamu) are kind of foods and beverages that are very popular among Indonesian people, both of them are causing discoloration on the surface of the composite resin. The objective was to identify the difference composite resin color change after soaking in sweet and sour sauce (cuko pempek) and turmeric-tamarind herbal drink. This study was experimental laboratory research with pre-test and post-test research design. The samples were 32 pieces of Nanohybrid composite resin with the size of 10 x 2 mm. 16 samples of each test were soaked in 5 ml “cuko pempek” and turmeric-tamarind herbal drink in 37 0 C temperature in 7 days. The color change was measured using spechtrophotometer (UV-2401 PC). Results: There are differences between Nanohybrid composite resin surface color change which were soaked in “cuko pempek” and turmeric-tamarind herbal drink which marked in an average change of dE*ab “cuko pempek” (4.7244) and turmeric and tamarind herbal drink (39.1944). The results of independent T-Test also showed a significant color change that is p = 0,000 (p <0.05). This study concluded that there were differences between Nanohybrid composite resin surface color change which are soaked in “cuko pempek” and turmeric-tamarind herbal drink.
Daya Antibakteri Ekstrak Daun Seledri (Apium graveolens L.) terhadap Porphyromonas gingivalis Anisa Luthfiyani; Peni Pujiastuti; Melok Aris W.
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 16 No 2 (2019)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/stoma.v16i2.23092

Abstract

Background: celery leaves contain antibacterial substances that can be used as medicine. These contents include flavonoids, saponins and tannins. Purpose: the aim of this study was to determine the antibacterial effect of celery leaves (Apium graveolens L.) on the growth of Porphyromonas gingivalis (P. gingivalis). Methods: celery leaves were extracted by maceration method with 96% ethanol. The antibacterial test method against P. gingivalis using the well diffusion method on BHI-A media. The concentrations of celery leaf extract used in this study were 6.25%, 12.5%, 25%, 50% and 100%. Result: The results showed that celery leaves extract (Apium graveolens L.) didn’t have the ability to inhibit the growth of Porphyromonas gingivalis. Conclusion: celery leaves didn’t have antibacterial effect against Porphyromonas gingivalis in 6,25%, 12.5%, 25%, 50% and 100% concentrations.
Efektifitas Tablet Effervescent Ekstrak Kulit Manggis (Garcinia mangostana L) sebagai Pembersih Gigi Tiruan Resin Akrilik terhadap Candida albicans Jovanna Andhara Arieputri; Dewi Kristiana; R. Rahardyan Parnaadji
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 16 No 2 (2019)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/stoma.v16i2.23088

Abstract

Denture stomatitis is inflammation of the oral mucosa in contact with the denture base caused by the fungus Candida albicans. Denture stomatitis can be prevented by cleaning the dentures either mechanically or chemically. Mangosteen peel extract has been shown to inhibit the growth of C. albicans, but its effectiveness as a denture cleaning agent needs to be improved. One way to increase effectiveness is by combining chemical cleansing and mechanical cleansing through effervescent tablets. The aim of the study was to determine the effectiveness of mangosteen peel extract effervescent tablets as an acrylic denture cleaner against C. albicans. Previously, the effervescent tablets of mangosteen peel extract were made with concentrations of 30% and 60%. Heat cured acrylic resin samples were incubated into a test tube containing C. albicans suspension for 24 hours at 37oC. Furthermore, the samples were immersed in effervescent tablets of mangosteen peel extract for 15 and 30 minutes. The number of C. albicans cells was counted using a spectrophotometer. The results showed that there was a significant reduction in the number of C. albicans cells attached to the plate surface after immersion in 30% and 60% effervescent tablets of mangosteen peel extract (p <0.05). Mangosteen peel extract effervescent tablets 60% more decreased the number of C. albicans cells. The duration of immersion did not show significantly different results (p> 0.05). Effervescent tablets of 60% concentration of mangosteen peel extract soaked for 15 minutes were the most effective as an acrylic resin denture cleaner against C. albicans.
Penatalaksanaan Periodontitis Kronik Pada Penderita Diabetes Mellitus Victoria Dewanti Arifiana; Nabila Prandita
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 16 No 2 (2019)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/stoma.v16i2.23093

Abstract

Diabetes mellitus (DM) is a metabolic disorder that can occur genetically and clinically, including heterogeneous with manifestations in the form of loss of tolerance for carbohydrates. One of the complications of diabetes mellitus in the field of dentistry is oral diabetes including dry mouth, gingivitis, calculus, alveolar bone resorption, and periodontitis. Periodontitis is an inflammatory disease of the tooth supporting tissue caused by a particular group of microorganisms usually derived from dental plaque which can result in the progressive destruction of the periodontal connective tissue and alveolar bone with pocket formation, recession, or both. This case report is to study the management of chronic periodontitis in DM sufferers. The 52-year-old female patient came with complaints of missing and perforated back teeth wanting treatment. The patient has a history of diabetes. The incidence of periodontitis in DM has a greater incidence rate, therefore the existence of glycemic control plays an important role in preventing any deterioration.

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